Mosmann TR, Cherwinski C, Bond MW, Giedlin MA, Coffman RL: Two types of murine helper T cell clones. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol. 1986, 136: 2348-2357.
CAS
PubMed
Google Scholar
Del Prete GF, De Carli M, Mastromauro C, Biagiotti R, Macchia D, Falagiani , Ricci M, Romagnani S: Purified protein derivative of Mycobacterium tuberculosis and excretory/secretori antigen(s) of Toxocara canis expand in vitro human T cells with stable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production. J Clin Invest. 1991, 88: 346-350. 10.1172/JCI115300.
Article
PubMed Central
CAS
PubMed
Google Scholar
Abbas AK, Murphy KM, Sher A: Functional diversity of helper T lymphocytes. Nature. 1996, 383: 787-793. 10.1038/383787a0.
Article
CAS
PubMed
Google Scholar
Romagnani S: The Th1/Th2 paradigm. Immunol Today. 1997, 18: 263-266. 10.1016/S0167-5699(97)80019-9.
Article
CAS
PubMed
Google Scholar
Rengarajan J, Szabo SJ, Glimcher LH: Transcriptional regulation of Th1/Th2 polarization. Immunol Today. 2000, 21: 479-483. 10.1016/S0167-5699(00)01712-6.
Article
CAS
PubMed
Google Scholar
Weaver CT, Harrington LE, Mangan PR, Gavrieli M, Murphy KM: Th17 and effector CD4 T cell lineage with regulatory T cell ties. Immunity. 2006, 24: 677-688. 10.1016/j.immuni.2006.06.002.
Article
CAS
PubMed
Google Scholar
Manetti R, Parronchi P, Giudizi MG, Piccinni MP, Maggi E, Trinchieri G, Romagnani S: Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells. J Exp Med. 1993, 177: 1199-1204. 10.1084/jem.177.4.1199.
Article
CAS
PubMed
Google Scholar
Amsen F, Blander JM, Lee GR, Tanigaki K, Honjo T, Flavell RA: Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells. Cell. 2004, 117: 515-526. 10.1016/S0092-8674(04)00451-9.
Article
CAS
PubMed
Google Scholar
Liotta F, Frosali F, Querci V, Mantei A, Filì L, Maggi L, Mazzinghi B, Angeli R, Ronconi E, Santarlasci V, Biagioli T, Lasagni L, Ballerini C, Parronchi P, Scheffold A, Cosmi L, Maggi E, Romagnani S, Annunziato F: Human immature myeloid dendritic cells trigger a Th2-polarizing program via Jagged-1/Notch interaction. J Allergy Clin Immunol. 2008,
Google Scholar
Fallon PG, Ballantyne SJ, Mangan NE, Barlow H, Davarma A, Hewett DR, McIlgorm A, Jolin HE, McKenzie AN: Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion. J Exp Med. 2006, 203: 1105-1116. 10.1084/jem.20051615.
Article
PubMed Central
CAS
PubMed
Google Scholar
Angkasekwinal P, Park H, Wang YH, Chang SH, Corry DB, Liu VJ, Zhu Z, Domg C: Interleukin 25 promotes the initiation of proallergic type responses. J Exp Med. 2007, 204: 1509-1517. 10.1084/jem.20061675.
Article
Google Scholar
Mosmann TR, Sad S: The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol Today. 1996, 17: 138-146. 10.1016/0167-5699(96)80606-2.
Article
CAS
PubMed
Google Scholar
Cua DJ, Scherlock J, Chen Y, Murphy CA, Joyce B, Seymour B, Lucian L, To W, Kwan S, Churakova T, Zurawski S, Wickwoski M, Lira SA, Gorman D, Kastelein RA, Sedgwick JD: Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature. 2003, 421: 744-748. 10.1038/nature01355.
Article
CAS
PubMed
Google Scholar
Murphy CA, Langrish CL, Chen Y, Blumenschein W, McClanahan T, Kastelein RA, Sedgwuick JD, Cua DJ: Divergent pro-and anti-inflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation. J Exp Med. 2003, 198: 1951-1958. 10.1084/jem.20030896.
Article
PubMed Central
CAS
PubMed
Google Scholar
Zhang GX, Gran B, Yu S, Li J, Siglienti I, Chen X, Kamoun M, Rostami A: Induction of experimental autoimmune encephalomyelitis in IL-12 receptor β2-deficiet mice. IL-12 responsiveness is not required in the pathogenesis of inflammatory demyelinization in the central nervous system. J Immunol. 2003, 170: 2153-2160.
Article
CAS
PubMed
Google Scholar
Langrish CL, Chen Y, Blumenschein WM, Mattson J, Basham B, Sedgwick JD, McClanahan T, Kalestein RA, Cua DJ: IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med. 2005, 201: 233-240. 10.1084/jem.20041257.
Article
PubMed Central
CAS
PubMed
Google Scholar
Aggarwal S, Ghilardi N, Xie MH, de Sauvage J, Gurney AL: Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J Biol Chem. 2003, 278: 1910-1914. 10.1074/jbc.M207577200.
Article
CAS
PubMed
Google Scholar
Park H, Yang XO, Chang SH, Nurieva R, Wang YH, Wang Y, Hood L, Zhu Z, Tian Q, Dong C: A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol. 2005, 6: 1069-1070. 10.1038/ni1261.
Article
Google Scholar
Harrington LE, Hatton RD, Mangan PR, Turner H, Murphy TL, Murphy KM, Weaver CT: Interleukin-17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol. 2005, 6: 1069-1070. 10.1038/ni1254.
Article
Google Scholar
Nakae S, Nambu A, Sudo K, Iwakura Y: Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice. J Immunol. 2003, 171: 6173-6177.
Article
CAS
PubMed
Google Scholar
Bettelli E, Kuchroo VK: IL-12-and IL-23-induced T helper cell subsets: birds of the same feather flock together. J Exp Med. 2005, 201: 169-171. 10.1084/jem.20042279.
Article
PubMed Central
CAS
PubMed
Google Scholar
Mackenzie BS, Kastelein RA, Cua DJ: Understanding the IL-23-IL-17 immune pathway. Trends Immunol. 2006, 27: 17-23. 10.1016/j.it.2005.10.003.
Article
Google Scholar
Bettelli E, Carrier Y, Gao W, Korn T, Strom TB, Oukka M, Weiner HL, Kuchroo VK: Reciprocal developmental pathways for the generation of pathogenic effector Th17 and regulatory T cells. Nature. 2006, 441: 235-238. 10.1038/nature04753.
Article
CAS
PubMed
Google Scholar
Mangan PR, Harrington LE, O'Quinn DB, Helms WS, Bullard DC, Elson CO, Hatton RD, Wahl SM, Schoeb TR, Weaver CT: Transforming growth factor beta induces development of the T(H)17 lineage. Nature. 2006, 441: 231-234. 10.1038/nature04754.
Article
CAS
PubMed
Google Scholar
Veldhoen M, Hocking RJ, Atkins CJ, Locksley RM, Stockinger B: TGF-beta in the context of an inflammatory cytokine milieu supports differentiation of IL-17-producing T cells. Immunity. 2006, 25: 179-189. 10.1016/j.immuni.2006.01.001.
Article
Google Scholar
Nurieva R, Yang XO, Martinez G, Zhang Y, Pasnopoulos AD, Ma L, Schluns K, Tian Q, Watowich SS, Jetten AM, Dong C: Essential autocrine regulation by IL-21 in the generation of inflammatory T cells. Nature. 2007, 448: 480-483. 10.1038/nature05969.
Article
CAS
PubMed
Google Scholar
Korn T, Bettelli E, Gao W, Awashi A, Jager A, Strom TB, Oukksa M, Kuchroo VK: IL-21 initiates an alternative pathway to onduce pro-inflammatory Th17 cells. Nature. 2007, 448: 484-487. 10.1038/nature05970.
Article
PubMed Central
CAS
PubMed
Google Scholar
Kimura A, Naka T, Kishimoto T: IL-6-dependent and -independent pathways in the development of interleukin-17-producing T helper cells. Proc Natl Acad Sci USA. 2007, 104: 12099-12104. 10.1073/pnas.0705268104.
Article
PubMed Central
CAS
PubMed
Google Scholar
Ivanov II, Mackenzie BS, Zhou L, Tadokoro CE, Lepelley A, LKafaille JJ, Cua DJ, Littman DR: The orphan nuclear receptor RORγt directs the differentiation program of proinflammatopry IL-17+ T helper cells. Cell. 2006, 126: 1121-1131. 10.1016/j.cell.2006.07.035.
Article
CAS
PubMed
Google Scholar
Yang XO, Pappau BP, Nurieva R, Akimzhanov A, Kang HS, Chung Y, Ma L, Shah B, Panopoulos AD, Schluns KS, Watowich SS, Tian Q, Jetten AM, Dong C: T helper 17 lineage differentiation is programmed by organ nuclear receptors RORα and RORγ. Immunity. 2008, 28: 29-39. 10.1016/j.immuni.2007.11.016.
Article
PubMed Central
CAS
PubMed
Google Scholar
Bryant VL, Ma CS, Avery DT, Li Y, Good KL, Corcoran LM, de Waal Malefyt R, Tangye SG: Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: predominant role of IL-21 produced by CXCR5+ T follicular helper cells. J Immunol. 2007, 179: 8180-8190.
Article
CAS
PubMed
Google Scholar
Zheng Y, Danilenko DM, Valdez P, Kasman I, Eastham-Anderson J, Wu J, Ouyang W: Interleukin-22, a Th17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis. Nature. 2007, 445: 648-651. 10.1038/nature05505.
Article
CAS
PubMed
Google Scholar
Zenewicz LA, Yancopoulos GD, Valenzuela DM, Murphy AL, Karow M, Flavell RA: Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation. Immunity. 2007, 27: 647-659. 10.1016/j.immuni.2007.07.023.
Article
PubMed Central
CAS
PubMed
Google Scholar
Lubberts E: IL17/Th17 targeting: On the road to prevent chronic destructive arthritis?. Cytokine. 2007, 41: 84-91. 10.1016/j.cyto.2007.09.014.
Article
PubMed
Google Scholar
Laurence A, Tato CT, Davidson TS, Kanno Y, Chen Z, Yao Z, Blank RB, Meylan F, Siegel R, Hennighausen L, Shevach EM, O'Shea JJ: Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation. Immunity. 2007, 26: 371-381. 10.1016/j.immuni.2007.02.009.
Article
CAS
PubMed
Google Scholar
Kleinsheck MA, Owyang A, Jooyce-Shaikh B, Langrish CL, Chen Y, Gorman DM, Blumenschein WM, McClanahan T, Brombacher F, Hurst SD, Kastelein RA, Cua DJ: IL-25 regulates Th17 function in autoimmune inflammation. J Exp Med. 2007, 204: 161-170. 10.1084/jem.20061738.
Article
Google Scholar
Fitzgerald DC, Ciric B, Touil T, Harle H, Grammatikopolou J, Das Sarma J, Gran B, Zhang G-X, Rostami A: Suppressive effect of IL-27 on encephalitogenic Th17 cells and the effector phase of experimental autoimmune encephalomyelitis. J Immunol. 2007, 179: 3268-3275.
Article
CAS
PubMed
Google Scholar
Awasthi A, Carrier Y, Peron JP, Bettelli E, Kamanaka M, Flavell RA, Kuchroo VK, Oukka M, Weiner HL: A dominant function for interleukin-27 in generating interleukin-10-producing anti-inflammatory T cells. Nat Immunol. 2007, 8: 1380-1389. 10.1038/ni1541.
Article
CAS
PubMed
Google Scholar
Fitzgerald DC, Zhang GX, El-Behi M, Fonseca-Kelly Z, Li H, Yu S, Saris CL, Bran B, Ciric B, Rostami A: Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin-27-stimulated T cells. Nat Immunol. 2007, 8: 1372-1379. 10.1038/ni1540.
Article
CAS
PubMed
Google Scholar
Chen Q, Ghilardi N, Baker T, Xie M-H, Gurner A, Grewal IS, de Sauvage FJ: Development of Th1-type immune responses requires the type I cytokine receptor TCCR. Nature 2000. 2007, 407: 916-920.
Google Scholar
Aujla S, Dubin PJ, Kolls JK: Th17 cells and mucosal host defence. Semin Immunol. 2007, 19: 377-382. 10.1016/j.smim.2007.10.009.
Article
PubMed Central
CAS
PubMed
Google Scholar
Zelante T, De Luca A, Bonifazi P, Montagnoli C, Bozza S, Moretti S, Belladonna ML, Vacca C, Conte C, Mosci P, Bistoni F, Puccetti P, Kastelein RA, Kopf M, Romani L: IL-23 and the Th17 pathway promote inflammation and impari antifungal immune resistance. Eur J Immunol. 2007, 37: 2695-2706. 10.1002/eji.200737409.
Article
CAS
PubMed
Google Scholar
Koenders MI, Lubberts E, Oppers-Walgren B, van den Bersselaar L, Helsen MM, Di Padova FE, Boots AM, Joosten LA, van den Berg WB: Blocking of interleukin-17 during reactivation of experimental arthritis prevents joint inflammation and bone erosion by decreasing RANKL and interleukin-1. Am J Pathol. 2005, 167: 141-149.
Article
PubMed Central
CAS
PubMed
Google Scholar
Uyttenhove C, Sommereyns C, Thèate I, Mivhiels T, Van Snick J: Anti-IL-17 autovaccine prevents clinical and histological manifestations of experimental autoimmune enecephalomyelitis. Ann N Y Acad Sci. 2007, 1110: 330-336. 10.1196/annals.1423.035.
Article
CAS
PubMed
Google Scholar
Ferber IA, Brocce S, Taylor Edwards C, Ridgway W, Dinisco C, Steinman L, Dal ton D, Fathman CG: Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE). J Immunol. 1996, 156: 5-7.
CAS
PubMed
Google Scholar
Kageyama Y, Koide Y, Yoshida A, Uchijima M, Arai T, Miyamoto S, Ozeki T, Hiyoshi M, Kushida K, Inoue T: Reduced susceptibility to collagen-induced arthritis in mice deficient in IFN-gamma receptor. J Immunol. 1998, 161: 1542-1548.
CAS
PubMed
Google Scholar
Thakker P, Leach MW, Kuang W, Benoit SE, Leonard JP, Marusic S: IL-23 is critical in the induction but not in the effector phase of experimental autoimmune encephalomyelitis. J Immunol. 2007, 178: 2589-2598.
Article
CAS
PubMed
Google Scholar
Gocke AR, Cravens PD, Ben LH, Hussain RZ, Northrop SC, Racke MK, Lovett-Racke AE: T-bet regulates the fate of Th1 and Th17 lymphocytes in autoimmunity. J Immunol. 2007, 178: 1341-1348.
Article
CAS
PubMed
Google Scholar
Kullberg MC, Jankovic D, Feng CG, Hue S, Gorelick PL, Mckenzie BS, Cua DJ, Powrie F, Cheever AW, Maloy KJ, Sher A: IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis. J Exp Med. 2006, 203: 2485-2494. 10.1084/jem.20061082.
Article
PubMed Central
CAS
PubMed
Google Scholar
Li M, Wan YY, Flavell RA: T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1-and Th17-cell differentiation. Immunity. 2007, 26: 579-591. 10.1016/j.immuni.2007.03.014.
Article
CAS
PubMed
Google Scholar
McGeachy MJ, Bak-Jensen KS, Chen Y, Tato CM, Blumenschein W, McClanahan T, Cua DJ: TGF-β and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain Th-cell-mediated pathology. Nat Immunol. 2007, 8: 1390-1397. 10.1038/ni1539.
Article
CAS
PubMed
Google Scholar
Zhang GX, Xiao BG, Bai XF, van der Meide PH, Orn A, Link H: Mice with IFN-gamma receptor deficiency are less susceptible to experimental autoimmune myasthenia gravis. J Immunol. 1999, 162: 3775-3781.
CAS
PubMed
Google Scholar
Yu S, Medling B, Yagita H, Braley-Mullen H: Characteristics of inflammatory cells in spontaneous autoimmune thyroiditis of NOD.H-2h4 mice. J Autoimmun. 2001, 16: 37-45. 10.1006/jaut.2000.0458.
Article
CAS
PubMed
Google Scholar
Haas C, Ryffel B, Le Hir M: IFN-gamma is essential for the development of autoimmune glomerulonephritis in MRL/Ipr mice. J Immunol. 1997, 158: 5484-5491.
CAS
PubMed
Google Scholar
Egwuagu CE, Sztein J, Mahdi RM, Li W, Chao-Chan C, Smith JA, Charukamnoetkanok P, Chepelinsky AB: IFN-gamma increases the severity and accelerates the onset of experimental auto-immune uveitis in transgenic rats. J Immunol. 1999, 162: 510-517.
CAS
PubMed
Google Scholar
Jones LS, Rizzo LV, Agarwal RK, Tarrant TK, Chan CC, Wiggert B, Caspi RR: IFN-gamma-deficient mice develop experimental autoimmune uveitis in the context of a deviant effector response. J Immunol. 1997, 158: 5997-6005.
CAS
PubMed
Google Scholar
Schwarting A, Tesch G, Kinoshita K, Maron R, Weiner HL, Kelley VR: IL-12 drives IFN-gamma-dependent autoimmune kidney disease in MRL-Fas(lpr) mice. J Immunol. 1999, 163: 6884-6891.
CAS
PubMed
Google Scholar
Schwarting A, Wada T, Kinoshita K, Tesch G, Kelley VR: IFN-gamma receptor signaling is essential for the initiation, acceleration, and destruction of autoimmune kidney disease in MRL-Fas(lpr) mice. J Immunol. 1998, 161: 494-503.
CAS
PubMed
Google Scholar
Wang B, Andre I, Gonzalez A, Katz JD, Aguet M, Benoist C, Mathis D: Interferon-gamma impacts at multiple points during the progression of autoimmune diabetes. Proc Natl Acad Sci USA. 1997, 94: 13844-13489. 10.1073/pnas.94.25.13844.
Article
PubMed Central
CAS
PubMed
Google Scholar
Finnegan A, Grusby MJ, Kaplan CD, O'Neill SK, Eibel H, Koreny T, Czipri M, Mikecz K, Zhang J: IL-4 and IL-12 regulate proteoglycan-induced arthritis through Stat-dependent mechanisms. J Immunol. 2002, 169: 3345-3352.
Article
CAS
PubMed
Google Scholar
Acosta-Rodriguez EV, Rivino L, Geginat J, Jarrossay D, Gattorno M, Lanzavecchia A, Sallusto F: Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells. Nat Immunol. 2007, 8: 639-646. 10.1038/ni1467.
Article
CAS
PubMed
Google Scholar
Annunziato F, Cosmi L, Santarlasci V, Maggi L, Liotta F, Mazzinghi B, Parente E, Filì L, Ferri S, Frosali F, Giudici F, Romagnani P, Parronchi P, Tonelli F, Maggi E, Romagnani S: Phenotypic and functional features of human Th17 cells. J Exp Med. 2007, 204: 1849-1861. 10.1084/jem.20070663.
Article
PubMed Central
CAS
PubMed
Google Scholar
Acosta-Rodriguez EV, Napoletani G, Lanzavecchia A, Sallusto F: Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17-producing human T helper cells. Nat Immunol. 2007, 8: 942-949. 10.1038/ni1496.
Article
CAS
PubMed
Google Scholar
Chen Z, Tato CM, Muul L, Laurence A, O'Shea JJ: Distinct regulation of interleukin-17 in human T helper lymphocytes. Arthritis Rheum. 2007, 56: 2936-2946. 10.1002/art.22866.
Article
PubMed Central
CAS
PubMed
Google Scholar
Wilson NJ, Boniface K, Chan JR, McKenzie B, Blumenschein WM, Mattson JD, Basham B, Smith K, Chen T, Morel F, Lecron J-C, Kastelein RA, Cua DJ, McClanahan TK, Bowman EP, de Waal Malefyt R: Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nat Immunol. 2007, 8: 950-957. 10.1038/ni1497.
Article
CAS
PubMed
Google Scholar
van Beelen AJ, Zelinkova Z, Taanman-Kueter EW, Muller FJ, Hommes DW, Zaat SAJ, Kapsenberg ML, de Jong EC: Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells. Immunity. 2007, 27: 1-10. 10.1016/j.immuni.2007.07.003.
Article
Google Scholar
Laurence A, O'Shea JJ: Th17 differentiation: of mice and men. Nat Immunol. 2007, 9: 903-905. 10.1038/ni0907-903.
Article
Google Scholar
Matusevicius D, Kivisakk P, He B, Kostulas N, Ozenci V, Fredrikson S, Link H: Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis. Mult Scler. 1999, 5: 101-104.
Article
CAS
PubMed
Google Scholar
Kebir H, Kteymborg K, Ifergan I, Dodelet-Devillers A, Cayrol R, Bernard M, Giuliani F, Arbour N, Becher B, Prat A: Human Th17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation. Nat Med. 2007, 13: 1173-1175. 10.1038/nm1651.
Article
CAS
PubMed
Google Scholar
Kotake S, Udagawa N, Takahashi N, Matsuzaki K, Itoh K, Ishiyama S, Saito S, Inoue K, Kamatani N, Gillespie MT, Martin TJ, Suda T: IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J Clin Invest. 1999, 103: 1345-1352. 10.1172/JCI5703.
Article
PubMed Central
CAS
PubMed
Google Scholar
Honorati MC, Meliconi R, Pulsatelli L, Cane S, Frizziero L, Facchini A: High in vivo expression of interleukin-17 receptor in synovial endothelial cells and chondrocytes from arthritis patients. Rheumatology. 2001, 40: 522-527. 10.1093/rheumatology/40.5.522.
Article
CAS
PubMed
Google Scholar
Wong CK, Ho CY, Li EK, Lam CW: Elevation of proinflammatory cytokine (IL-18, IL-17, IL-12) and Th2 cytokine (IL-4) concentrations in patients with systemic lupus erythematosus. Lupus. 2000, 9: 589-593. 10.1191/096120300678828703.
Article
CAS
PubMed
Google Scholar
Kurasawa K, Hirose K, Sano H, Endo H, Shinkai H, Nawata Y, Takabayashi K, Iwamoto I: Increased interleukin-17 production in patients with systemic sclerosis. Arthritis Rheum. 2000, 43: 2455-2463. 10.1002/1529-0131(200011)43:11<2455::AID-ANR12>3.0.CO;2-K.
Article
CAS
PubMed
Google Scholar
Hirota K, Yoshitomi H, Hashimoto M, Maeda S, Teradaira S, Sugimoto N, Yamaguchi T, Naomura T, Ito H, Nakamura T, Sakaguchi N, Sakaguchi S: Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model. J Exp Med. 2007, 204: 2803-2812. 10.1084/jem.20071397.
Article
PubMed Central
CAS
PubMed
Google Scholar
Nielsen OH, Kirman I, Rudiger N, Hendel J, Vainer B: Upregulation of interleukin-12 and -17 in active inflammatory bowel disease. Scand J Gastroenterol. 2003, 38: 180-185. 10.1080/00365520310000672.
Article
CAS
PubMed
Google Scholar
Fujino S, Andoh A, Bamba S, Ogawa A, Hata K, Araki Y, Bamba T, Fujiyama Y: Increased expression of interleukin 17 in inflammatory bowel disease. Gut. 2003, 52: 65-70. 10.1136/gut.52.1.65.
Article
PubMed Central
CAS
PubMed
Google Scholar
Seiderer J, Elben I, Diegelmann J, Glas J, Stallhofer J, Tillack C, Pfennig S, Jurgens M, Schmechel S, Konrad A, Goke B, Ochsenkuhn T, Muller-Myhsok B, Lohse P, Brands S: Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL-17F p.His161Arg polymorphism in IBD. Inflamm Bowel Dis. 2008, 14: 437-445. 10.1002/ibd.20339.
Article
PubMed
Google Scholar
Albanesi C, Cavani A, Girolomoni G: IL-17 is produced by nickel-specific T lymphocytes and regulates ICAM-1 expression and chemokine production in human keratinmocytes: synergistic effects with IFN-gamma and TNF-alpha. J Immunol. 1999, 162: 494-502.
CAS
PubMed
Google Scholar
van Beleen AJ, Teunissen MBM, Kapsenberg ML, de Jong EC: Interleukin-17 in inflammatory skin disorders. Curr Opin Allergy Clin Immunol. 2007, 7: 374-381.
Article
Google Scholar
Yamada H, Nakashima Y, Okazaki K, Mawatari T, Fukushi JI, Kaibara N, Hori A, Iwamoto Y, Yoshikai Y: Th1 but not Th17 cells predominate in the joints of patients with rheumatoid arthritis. Ann Rheum Dis. 2007,
Google Scholar
Bullens DM, Truyen E, Coteur L, Dilissen E, Hellings PW, Dupont LJ, Ceuppens JL: IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocyte influx?. Respir Res. 2006, 7: 135-143. 10.1186/1465-9921-7-135.
Article
PubMed Central
PubMed
Google Scholar