- Open Access
Erratum to: Association of the FCRL3 gene with rheumatoid arthritis: a further example of population specificity?
Arthritis Research & Therapy volume 10, Article number: 405 (2008)
- The original article was published in Arthritis Research & Therapy 2006 8:R117
Following publication of our article  we have noticed the following error in nomenclature: All four polymorphisms studied were referred to as FCRL3-169*C/T.
FCRL3-169*C/T (fclr3_3, rs7528684) is correctly named.
FCRL3-169*C/T (fclr3_4, rs11264799) should be FCRL3-110*C/T (fclr3_4, rs11264799).
FCRL3-169*C/T (fclr3_5, rs945635) should be FCRL3+358*C/G (fclr3_5, rs945635).
FCRL3-169*C/T (fclr3_6, rs3761959) should be FCRL3+1370*A/G (fclr3_6, rs3761959).
Thus, Table 1 should appear as shown.
Within 'Patients and methods', the paragraph 'Polymorphisms selected' should read as follows:
Four SNPs – FCRL3-169*C/T (fclr3_3, rs7528684), FCRL3-110*C/T (fclr3_4, rs11264799), FCRL3+358*C/G (fclr3_5, rs945635) and FCRL3+1370*A/G (fclr3_6, rs3761959) – were initially selected for investigation because they had all been associated with RA in the Japanese population on single-point analysis, because the SNPs formed a haplotype associated with RA and because the most probable disease causal SNP (FCRL3-169*C/T (fclr3_3, rs7528684)) was included .
The second paragraph of 'Results' should read as follows:
No deviation from Hardy–Weinberg expectations was observed for any of the SNPs in either cases or controls. Interim analysis after genotyping a subset of the total cohort revealed that extensive linkage disequilibrium was present across the four SNPs tested. Indeed, the D' value between all the SNPs was 0.98 while the correlation between SNPs FCRL3-169*C/T (fclr3_3, rs7528684), FCRL3+358*C/G fclr3_5 (rs945635) and FCRL3+1370*A/G fclr3_6 (rs3761959) was also 0.98 in this sample. The correlation between these SNPs and FCRL3-110*C/T fclr3_4 (rs11264799) was 0.6 or greater, reflecting the difference in allele frequency of this SNP compared with the others. Hence, genotyping of all four SNPs was unnecessary and, in the remaining samples, only the putative disease causal polymorphism was genotyped.
The above changes in no way affect the conclusions of the study.
Eyre S, Bowes J, Potter C, Worthington J, Barton A: Association of the FCRL3 gene with rheumatoid arthritis: a further example of population specificity?. Arthritis Research & Therapy. 2006, 8: R117-10.1186/ar2006.
The authors declare that they have no competing interests.
The online version of the original article can be found at 10.1186/ar2006
About this article
Cite this article
Eyre, S., Bowes, J., Potter, C. et al. Erratum to: Association of the FCRL3 gene with rheumatoid arthritis: a further example of population specificity?. Arthritis Res Ther 10, 405 (2008). https://doi.org/10.1186/ar2469