Braun J, Bollow M, Remlinger G, Eggens U, Rudwaleit M, Distler A, Sieper J: Prevalence of spondylarthropathies in HLA-B27 positive and negative blood donors. Arthritis Rheum. 1998, 41: 58-67. 10.1002/1529-0131(199801)41:1<58::AID-ART8>3.0.CO;2-G.
Article
CAS
PubMed
Google Scholar
Braun J, Sieper J: The sacroiliac joint in the spondyloarthropathies. Curr Opin Rheumatol. 1996, 8: 275-287. 10.1097/00002281-199607000-00003.
Article
CAS
PubMed
Google Scholar
Baraliakos X, Landewe R, Hermann KG, Listing J, Golder W, Brandt J, Rudwaleit M, Bollow M, Sieper J, Heijde van der D, Braun J: Inflammation in ankylosing spondylitis: a systematic description of the extent and frequency of acute spinal changes using magnetic resonance imaging. Ann Rheum Dis. 2005, 64: 730-734. 10.1136/ard.2004.029298.
Article
PubMed Central
CAS
PubMed
Google Scholar
Baraliakos X, Listing J, Rudwaleit M, Haibel H, Brandt J, Sieper J, Braun J: Progression of radiographic damage in patients with ankylosing spondylitis: defining the central role of syndesmophytes. Ann Rheum Dis. 2007, 66: 910-915. 10.1136/ard.2006.066415.
Article
PubMed Central
CAS
PubMed
Google Scholar
Wanders A, Landewe R, Dougados M, Mielants H, Linden van der S, Heijde van der D: Association between radiographic damage of the spine and spinal mobility for individual patients with ankylosing spondylitis: can assessment of spinal mobility be a proxy for radiographic evaluation?. Ann Rheum Dis. 2005, 64: 988-994. 10.1136/ard.2004.029728.
Article
PubMed Central
CAS
PubMed
Google Scholar
Braun J, Heijde van der D: Imaging and scoring in ankylosing spondylitis. Best Pract Res Clin Rheumatol. 2002, 16: 573-604.
Article
CAS
PubMed
Google Scholar
Heuft-Dorenbosch L, Landewe R, Weijers R, Wanders A, Houben H, Linden van der S, Heijde van der D: Combining information obtained from magnetic resonance imaging and conventional radiographs to detect sacroiliitis in patients with recent onset inflammatory back pain. Ann Rheum Dis. 2006, 65: 804-808. 10.1136/ard.2005.044206.
Article
PubMed Central
CAS
PubMed
Google Scholar
Braun J, Bollow M, Sieper J: Radiologic diagnosis and pathology of the spondyloarthropathies. Rheum Dis Clin North Am. 1998, 24: 697-735. 10.1016/S0889-857X(05)70038-7.
Article
CAS
PubMed
Google Scholar
Baraliakos X, Hermann KG, Landewe R, Listing J, Golder W, Brandt J, Rudwaleit M, Bollow M, Sieper J, Heijde van der D, Braun J: Assessment of acute spinal inflammation in patients with ankylosing spondylitis by magnetic resonance imaging (MRI): a comparison between contrast enhanced T1 and short-tau inversion recovery (STIR) sequences. Ann Rheum Dis. 2005, 64: 1141-1144. 10.1136/ard.2004.031609.
Article
PubMed Central
CAS
PubMed
Google Scholar
Creemers MC, Franssen MJ, van't Hof MA, Gribnau FW, Putte van de LB, van Riel PL: Assessment of outcome in ankylosing spondylitis: an extended radiographic scoring system. Ann Rheum Dis. 2005, 64: 127-129. 10.1136/ard.2004.020503.
Article
PubMed Central
CAS
PubMed
Google Scholar
Wanders AJ, Landewe RB, Spoorenberg A, Dougados M, Linden van der S, Mielants H, Tempel van der H, Heijde van der DM: What is the most appropriate radiologic scoring method for ankylosing spondylitis? A comparison of the available methods based on the Outcome Measures in Rheumatology Clinical Trials filter. Arthritis Rheum. 2004, 50: 2622-2632. 10.1002/art.20446.
Article
PubMed
Google Scholar
Spoorenberg A, de Vlam K, Linden van der S, Dougados M, Mielants H, Tempel van de H, Heijde van der D: Radiological scoring methods in ankylosing spondylitis. Reliability and change over 1 and 2 years. J Rheumatol. 2004, 31: 125-132.
PubMed
Google Scholar
Braun J, Baraliakos X, Golder W, Brandt J, Rudwaleit M, Listing J, Bollow M, Sieper J, Heijde Van Der D: Magnetic resonance imaging examinations of the spine in patients with ankylosing spondylitis, before and after successful therapy with infliximab: evaluation of a new scoring system. Arthritis Rheum. 2003, 48: 1126-1136. 10.1002/art.10883.
Article
CAS
PubMed
Google Scholar
Rudwaleit M, Baraliakos X, Listing J, Brandt J, Sieper J, Braun J: Magnetic resonance imaging of the spine and the sacroiliac joints in ankylosing spondylitis before and during therapy with etanercept. Ann Rheum Dis. 2005, 64: 1305-1310. 10.1136/ard.2004.032441.
Article
PubMed Central
CAS
PubMed
Google Scholar
Sieper J, Baraliakos X, Listing J, Brandt J, Haibel H, Rudwaleit M, Braun J: Persistent reduction of spinal inflammation as assessed by magnetic resonance imaging in patients with ankylosing spondylitis after 2 yrs of treatment with the anti-tumour necrosis factor agent infliximab. Rheumatology (Oxford). 2005, 44: 1525-1530. 10.1093/rheumatology/kei046.
Article
CAS
Google Scholar
Braun J, Landewe R, Hermann KG, Han J, Yan S, Williamson P, Heijde van der D: Major reduction in spinal inflammation in patients with ankylosing spondylitis after treatment with infliximab: results of a multicenter, randomized, double-blind, placebo-controlled magnetic resonance imaging study. Arthritis Rheum. 2006, 54: 1646-1652. 10.1002/art.21790.
Article
CAS
PubMed
Google Scholar
Baraliakos X, Davis J, Tsuji W, Braun J: Magnetic resonance imaging examinations of the spine in patients with ankylosing spondylitis before and after therapy with the tumor necrosis factor alpha receptor fusion protein etanercept. Arthritis Rheum. 2005, 52: 1216-1223. 10.1002/art.20977.
Article
CAS
PubMed
Google Scholar
Braun J, Bollow M, Neure L, Seipelt E, Seyrekbasan F, Herbst H, Eggens U, Distler A, Sieper J: Use of immunohistologic and in situ hybridization techniques in the examination of sacroiliac joint biopsy specimens from patients with ankylosing spondylitis. Arthritis Rheum. 1995, 38: 499-505. 10.1002/art.1780380407.
Article
CAS
PubMed
Google Scholar
François RJ, Neure L, Sieper J, Braun J: Immunohistological examination of open sacroiliac biopsies of patients with ankylosing spondylitis: detection of tumour necrosis factor {alpha} in two patients with early disease and transforming growth factor {beta} in three more advanced cases. Ann Rheum Dis. 2006, 65: 713-720. 10.1136/ard.2005.037465.
Article
PubMed Central
PubMed
Google Scholar
Lories RJ, Derese I, Luyten FP: Modulation of bone morphogenetic protein signaling inhibits the onset and progression of ankylosing enthesitis. J Clin Invest. 2005, 115: 1571-1579. 10.1172/JCI23738.
Article
PubMed Central
CAS
PubMed
Google Scholar
Braun J, Brandt J, Listing J, Zink A, Alten R, Golder W, Gromnica-Ihle E, Kellner H, Krause A, Schneider M, Sorensen H, Zeidler H, Thriene W, Sieper J: Treatment of active ankylosing spondylitis with infliximab: a randomised controlled multicentre trial. Lancet. 2002, 359: 1187-1193. 10.1016/S0140-6736(02)08215-6.
Article
CAS
PubMed
Google Scholar
Braun J, Deodhar A, Dijkmans B, Geusens P, Sieper J, Williamson P, Xu W, Visvanathan S, Baker D, Goldstein N, Heijde van der D: Efficacy and safety of infliximab in patients with ankylosing spondylitis over a two-year period. Ann Rheum Dis. 2008, 59: 1270-1278. .
CAS
Google Scholar
Davis JC, Heijde van der DM, Braun J, Dougados M, Cush J, Clegg D, Inman RD, Kivitz A, Zhou L, Solinger A, Tsuji W: Sustained durability and tolerability of etanercept in ankylosing spondylitis for 96 weeks. Ann Rheum Dis. 2005, 64: 1557-1562. 10.1136/ard.2004.035105.
Article
PubMed Central
CAS
PubMed
Google Scholar
Baraliakos X, Brandt J, Listing J, Haibel H, Sorensen H, Rudwaleit M, Sieper J, Braun J: Outcome of patients with active ankylosing spondylitis after two years of therapy with etanercept: Clinical and magnetic resonance imaging data. Arthritis Rheum. 2005, 53: 856-863. 10.1002/art.21588.
Article
CAS
PubMed
Google Scholar
Braun J, Baraliakos X, Golder W, Hermann KG, Listing J, Brandt J, Rudwaleit M, Zuehlsdorf S, Bollow M, Sieper J, Heijde van der D: Analysing chronic spinal changes in ankylosing spondylitis: a systematic comparison of conventional x rays with magnetic resonance imaging using established and new scoring systems. Ann Rheum Dis. 2004, 63: 1046-1055. 10.1136/ard.2003.019968.
Article
PubMed Central
CAS
PubMed
Google Scholar
Baraliakos X, Listing J, Rudwaleit M, Brandt J, Sieper J, Braun J: Radiographic progression in patients with ankylosing spondylitis after 2 years of treatment with the tumour necrosis factor alpha antibody infliximab. Ann Rheum Dis. 2005, 64: 1462-1466. 10.1136/ard.2004.033472.
Article
PubMed Central
CAS
PubMed
Google Scholar
Heijde van der D, Landewe R, Einstein S, Ory P, Vosse D, Ni L, Lin SL, Tsuji W, Davis JC: Radiographic progression of ankylosing spondylitis after up to two years of treatment with etanercept. Arthritis Rheum. 2008, 58: 1324-1331. 10.1002/art.23471.
Article
PubMed
Google Scholar
Baraliakos X, Listing J, Brandt J, Haibel H, Rudwaleit M, Sieper J, Braun J: Radiographic progression in patients with ankylosing spondylitis after 4 yrs of treatment with the anti-TNF-alpha antibody infliximab. Rheumatology (Oxford). 2007, 46: 1450-1453. 10.1093/rheumatology/kem166.
Article
CAS
Google Scholar
Diarra D, Stolina M, Polzer K, Zwerina J, Ominsky MS, Dwyer D, Korb A, Smolen J, Hoffmann M, Scheinecker C, Heide van der D, Landewe R, Lacey D, Richards WG, Schett G: Dickkopf-1 is a master regulator of joint remodeling. Nat Med. 2007, 13: 156-163. 10.1038/nm1538.
Article
CAS
PubMed
Google Scholar
Lories RJ, Derese I, de Bari C, Luyten FP: Evidence for uncoupling of inflammation and joint remodeling in a mouse model of spondylarthritis. Arthritis Rheum. 2007, 56: 489-497. 10.1002/art.22372.
Article
PubMed
Google Scholar
Linden van der S, Valkenburg HA, Cats A: Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria. Arthritis Rheum. 1984, 27: 361-368. 10.1002/art.1780270401.
Article
PubMed
Google Scholar
Braun J, Brandt J, Listing J, Zink A, Alten R, Burmester G, Golder W, Gromnica-Ihle E, Kellner H, Schneider M, Sorensen H, Zeidler H, Reddig J, Sieper J: Long-term efficacy and safety of infliximab in the treatment of ankylosing spondylitis: an open, observational, extension study of a three-month, randomized, placebo-controlled trial. Arthritis Rheum. 2003, 48: 2224-2233. 10.1002/art.11104.
Article
CAS
PubMed
Google Scholar
Braun J, Baraliakos X, Zelder C, Seemayer C, Gay R, Boehm H, Gay S, Neidhart M: Clinical and histopathological findings in patients with ankylosing spondylitis before and after surgical treatment for axis correction and erection of the spine. Ann Rheum Dis. 2008
Google Scholar
Baraliakos X, Listing J, Recke von der A, Braun J: Radiographic progression in ankylosing spondylitis (AS) – the natural course. A retrospective cohort study. Oral presentation given at: Annual Scientific Meeting of the American College of Rheumatology; 6–11. 2007, November ; Boston, MA
Google Scholar
Heide Van der D, Landewe R, Deodhar A, Baker D, Han J, Xu W, Williamson P, Houben H, Baraliakos X, Braun J: Radiographic progression in patients with ankylosing spondylitis after 2 years of treatment not inhibited with infliximab. Ann Rheum Dis. 2007, 66 (Suppl II): 85-
Google Scholar
Smolen JS, Heijde Van Der DM, St Clair EW, Emery P, Bathon JM, Keystone E, Maini RN, Kalden JR, Schiff M, Baker D, Han C, Han J, Bala M: Predictors of joint damage in patients with early rheumatoid arthritis treated with high-dose methotrexate with or without concomitant infliximab: results from the ASPIRE trial. Arthritis Rheum. 2006, 54: 702-710. 10.1002/art.21678.
Article
CAS
PubMed
Google Scholar
Schett G, Landewe R, Heijde van der D: Tumour necrosis factor blockers and structural remodelling in ankylosing spondylitis: what is reality and what is fiction?. Ann Rheum Dis. 2007, 66: 709-711. 10.1136/ard.2007.071159.
Article
PubMed Central
CAS
PubMed
Google Scholar
Appel H, Loddenkemper C, Grozdanovic Z, Ebhardt H, Dreimann M, Hempfing A, Stein H, Metz-Stavenhagen P, Rudwaleit M, Sieper J: Correlation of histopathological findings and magnetic resonance imaging in the spine of patients with ankylosing spondylitis. Arthritis Res Ther. 2006, 8: R143-10.1186/ar2035.
Article
PubMed Central
PubMed
Google Scholar
Sieper J, Appel H, Braun J, Rudwaleit M: Critical appraisal of assessment of structural damage in ankylosing spondylitis: implications for treatment outcomes. Arthritis Rheum. 2008, 58: 649-656. 10.1002/art.23260.
Article
PubMed
Google Scholar
Heijde van der D, Dijkmans B, Geusens P, Sieper J, DeWoody K, Williamson P, Braun J, Ankylosing Spondylitis Study for the Evaluation of Recombinant Infliximab Therapy Study Group: Efficacy and safety of infliximab in patients with ankylosing spondylitis: results of a randomized, placebo-controlled trial (ASSERT). Arthritis Rheum. 2005, 52: 582-591. 10.1002/art.20852.
Article
PubMed
Google Scholar
Visvanathan S, Wagner C, Marini JC, Baker D, Gathany T, Han J, Heijde van der D, Braun J: Inflammatory biomarkers, disease activity, and spinal disease measures in patients with ankylosing spondylitis after treatment with infliximab. Ann Rheum Dis. 2008, 67: 511-517. 10.1136/ard.2007.071605.
Article
PubMed Central
CAS
PubMed
Google Scholar
Gengenbacher M, Sebald HJ, Villiger PM, Hofstetter W, Seitz M: Infliximab inhibits bone resorption by circulating osteoclast precursor cells in patients with rheumatoid arthritis and ankylosing spondylitis. Ann Rheum Dis. 2008, 67: 620-624. 10.1136/ard.2007.076711.
Article
CAS
PubMed
Google Scholar
Allali F, Breban M, Porcher R, Maillefert JF, Dougados M, Roux C: Increase in bone mineral density of patients with spondyloarthropathy treated with anti-tumour necrosis factor alpha. Ann Rheum Dis. 2003, 62: 347-349. 10.1136/ard.62.4.347.
Article
PubMed Central
CAS
PubMed
Google Scholar
Romanus R, Yden S: Destructive and ossifying spondylitic changes in rheumatoid ankylosing spondylitis. Acta Orthop Scand. 1952, 22: 88-99.
Article
CAS
PubMed
Google Scholar
Engfeldt B, Romanus R, Yden S: Histological studies of pelvo-spondylitis ossificans (ankylosing spondylitis) correlated with clinical and radiological findings. Ann Rheum Dis. 1954, 13: 219-228. 10.1136/ard.13.3.219.
Article
PubMed Central
CAS
PubMed
Google Scholar