Braun J, Bollow M, Remlinger G, Eggens U, Rudwaleit M, Distler A, Sieper J: Prevalence of spondyloarthropathies in HLA-B27 positive and negative blood donors. Arthritis Rheum. 1998, 41: 58-67. 10.1002/1529-0131(199801)41:1<58::AID-ART8>3.0.CO;2-G.
Article
CAS
PubMed
Google Scholar
Braun J, Bollow M, Neure L, Seipelt E, Seyrekbasan F, Herbst H, Eggens U, Distler A, Sieper J: Use of immunohistologic and in situ hybridization techniques in the examination of sacroiliac joint biopsy specimens from patients with ankylosing spondylitis. Arthritis Rheum. 1995, 38: 499-505. 10.1002/art.1780380407.
Article
CAS
PubMed
Google Scholar
Heijde van der D, Landewé , Einstein S, Ory P, Vosse D, Ni L, Lin S-L, Tsuji W, Davis JC: Radiographic progression of ankylosing spondylitis after up to two years of treatment with etanercept. Arthritis Rheum. 2008, 58: 1324-1331. 10.1002/art.23471.
Article
PubMed
Google Scholar
Heijde van der D, Landewé R, Baraliakos X, Houben H, van Tubergen A, Williamson P, Xu W, Baker D, Goldstein N, Braun J, Ankylosing Spondylitis Study for the Evaluation of Recombinant Infliximab Therapy Study Group: Radiographic findings following two years of infliximab therapy in patients with ankylosing spondylitis. Arthritis Rheum. 2008, 58: 3063-3070. 10.1002/art.23901.
Article
PubMed
Google Scholar
Heijde van der D, Kivitz A, Schiff MH, Sieper J, Dijkmans BAC, Braun J, Dougados M, Reveille JD, Wong RL, Kupper H, Davis JC, ATLAS Study Group: Efficacy and safety of adalimumab in patients with ankylosing spondylitis: results of a multicenter, randomized, double-blind, placebo-controlled trial. Arthritis Rheum. 2006, 54: 2136-2146. 10.1002/art.21913.
Article
PubMed
Google Scholar
Maksymowych WP, Rahman P, Keystone E, Wong R, Inman R, for the M03-606 Study Group: Efficacy of adalimumab in active ankylosing spondylitis (AS)-Results of the Canadian AS study [abstract]. Arthritis Rheum. 2005, 52: S217-
Google Scholar
Heijde van der D, Schiff MH, Sieper J, Kivitz A, Wong RL, Kupper H, Dijkmans BAC, Mease PJ, Davis JC, ATLAS Study Group: Adalimumab effectiveness for the treatment of ankylosing spondylitis is maintained for up to 2 years: long-term results from the ATLAS trial. Ann Rheum Dis. 2009, 68: 922-929. 10.1136/ard.2007.087270.
Article
PubMed Central
PubMed
Google Scholar
Keystone EC, Kavanaugh AF, Sharp JT, Tannenbaum H, Hua Y, Teoh LS, Fischkoff SA, Chartash EK: Radiographic, clinical, and functional outcomes of treatment with adalimumab (a human anti-tumor necrosis factor monoclonal antibody) in patients with active rheumatoid arthritis receiving concomitant methotrexate therapy: a randomized, placebo-controlled, 52-week trial. Arthritis Rheum. 2004, 50: 1400-1411. 10.1002/art.20217.
Article
CAS
PubMed
Google Scholar
Mease PJ, Kivitz AJ, Burch FX, Siegel EL, Cohen SB, Ory P, Salonen D, Rubenstein J, Sharp JT, Tsuji W: Etanercept treatment of psoriatic arthritis: safety, efficacy, and effect on disease progression. Arthritis Rheum. 2004, 50: 2264-2272. 10.1002/art.20335.
Article
CAS
PubMed
Google Scholar
Heijde van der D, Klareskog L, Rodriguez-Valverde V, Condreanu C, Bolosiu H, Melo-Gomes J, Tornero-Molina J, Wajdula J, Pedersen R, Fatenejad S, TEMPO Study Investigators: Comparison of etanercept and methotrexate, alone and combined, in the treatment of rheumatoid arthritis: two-year clinical and radiographic results from the TEMPO study, a double-blind, randomized trial. Arthritis Rheum. 2006, 54: 1063-1074. 10.1002/art.21655.
Article
PubMed
Google Scholar
Kavanaugh A, Antoni CE, Gladman D, Wassenberg S, Zhou B, Beutler A, Keenan G, Burmester G, Furst DE, Weisman MH, Kalden JR, Smolen J, Heijde van der D: The Infliximab Multinational Psoriatic Arthritis Controlled Trial (IMPACT): results of radiographic analyses after 1 year. Ann Rheum Dis. 2006, 65: 1038-1043. 10.1136/ard.2005.045658.
Article
PubMed Central
CAS
PubMed
Google Scholar
Ritchlin CT, Haas-Smith SA, Li P, Hicks DG, Schwarz EM: Mechanisms of TNF-alpha- and RANKL-mediated osteoclastogenesis and bone resorption in psoriatic arthritis. J Clin Invest. 2003, 111: 821-831.
Article
PubMed Central
CAS
PubMed
Google Scholar
Redlich K, Hayer S, Ricci R, David JP, Tohidast-Akrad M, Kollias G, Steiner G, Smolen JS, Wagner EF, Schett G: Osteoclasts are essential for TNF-alpha-mediated joint destruction. J Clin Invest. 2002, 110: 1419-1427.
Article
PubMed Central
CAS
PubMed
Google Scholar
Lam J, Takeshita S, Barker JE, Kanagawa O, Ross FP, Teitelbaum SL: TNF-alpha induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand. J Clin Invest. 2000, 106: 1481-1488. 10.1172/JCI11176.
Article
PubMed Central
CAS
PubMed
Google Scholar
Heijde van der D, Landewé R: Selection of a method for scoring radiographs for ankylosing spondylitis clinical trials, by the Assessment in Ankylosing Spondylitis Working Group and OMERACT. J Rheumatol. 2005, 32: 2048-2049.
PubMed
Google Scholar
Heijde van der D, Landewé R, Linden van der S: How should treatment effect on spinal radiographic progression in patients with ankylosing spondylitis be measured?. Arthritis Rheum. 2005, 52: 1979-1985. 10.1002/art.21133.
Article
PubMed
Google Scholar
Wanders AJ, Landewé RB, Spoorenberg A, Dougados M, Linden van der S, Mielants H, Tempel van der H, Heijde van der DM: What is the most appropriate radiologic scoring method for ankylosing spondylitis? A comparison of the available methods based on the Outcome Measures in Rheumatology Clinical Trials filter. Arthritis Rheum. 2004, 50: 2622-2632. 10.1002/art.20446.
Article
PubMed
Google Scholar
Creemers MC, Franssen MJ, van't Hof MA, Gribnau FW, Putte van de LB, van Riel PL: Assessment of outcome in ankylosing spondylitis: an extended radiographic scoring system. Ann Rheum Dis. 2005, 64: 127-129. 10.1136/ard.2004.020503.
Article
PubMed Central
CAS
PubMed
Google Scholar
Wanders A, Landewé R, Dougados M, Mielants H, Linden van der S, Heijde van der D: Association between radiographic damage of the spine and spinal mobility for individual patients with ankylosing spondylitis: can assessment of spinal mobility be a proxy for radiologic evaluation?. Ann Rheum Dis. 2005, 64: 988-994. 10.1136/ard.2004.029728.
Article
PubMed Central
CAS
PubMed
Google Scholar
Powell A, Keeling SO, Lambert RG, Russell AS, Maksymowych WP: Scoring of radiographic progression over 2 years with the mSASSS in ankylosing spondylitis: does training improve reliability?. Arthritis Rheum. 2007, 56: S256-10.1002/art.22818.
Article
Google Scholar
Wanders A, Heijde van der D, Landewé R, Béhier JM, Calin A, Olivieri I, Zeidler H, Dougados M: Nonsteroidal antiinflammatory drugs reduce radiographic progression in patients with ankylosing spondylitis: a randomized clinical trial. Arthritis Rheum. 2005, 52: 1756-1765. 10.1002/art.21054.
Article
CAS
PubMed
Google Scholar
Baraliakos X, Listing J, Brandt J, Haibel H, Rudwaleit M, Sieper J, Braun J: Radiographic progression in patients with ankylosing spondylitis after 4 yrs of treatment with the anti-TNF-alpha antibody infliximab. Rheumatology (Oxford). 2007, 46: 1450-1453. 10.1093/rheumatology/kem166.
Article
CAS
Google Scholar
Sieper J, Appel H, Braun J, Rudwaleit M: Critical appraisal of assessment of structural damage in ankylosing spondylitis. Arthritis Rheum. 2008, 58: 649-656. 10.1002/art.23260.
Article
PubMed
Google Scholar
Linden van der S, Valkenburg HA, Cats A: Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria. Arthritis Rheum. 1984, 27: 361-368. 10.1002/art.1780270401.
Article
PubMed
Google Scholar
Maksymowych WP, Rahman P, Shojania K, Olszynski WP, Thomson GTD, Ballal S, Wong RL, Inman RD, M03-606 Study Group: Beneficial effects of adalimumab on biomarkers reflecting structural damage in patients with ankylosing spondylitis. J Rheumatol. 2008, 35: 2030-2037.
CAS
PubMed
Google Scholar
Maksymowych WP, Landewé R, Conner-Spady B, Dougados M, Mielants H, Tempel van der H, Poole AR, Wang N, Heijde van der D: Serum matrix metalloproteinase 3 is an independent predictor of structural damage progression in patients with ankylosing spondylitis. Arthritis Rheum. 2007, 56: 1846-1853. 10.1002/art.22589.
Article
CAS
PubMed
Google Scholar
Bárdos T, Szabó Z, Czipri M, Vermes C, Tunyogi-Csapó M, Urban RM, Mikecz K, Glant TT: A longitudinal study on an autoimmune murine model of ankylosing spondylitis. Ann Rheum Dis. 2005, 64: 981-987. 10.1136/ard.2004.029710.
Article
PubMed Central
PubMed
Google Scholar
Lories RJ, Daans M, Derese I, Matthys P, Kasran A, Tylzanowski P, Ceuppens JL, Luyten FP: Noggin haploinsufficiency differentially affects tissue responses in destructive and remodeling arthritis. Arthritis Rheum. 2006, 54: 1736-1746. 10.1002/art.21897.
Article
CAS
PubMed
Google Scholar
Lories RJ, Derese I, de Bari C, Luyten FP: Evidence for uncoupling of inflammation and joint remodeling in a mouse model of spondylarthritis. Arthritis Rheum. 2007, 56: 489-497. 10.1002/art.22372.
Article
PubMed
Google Scholar
Baraliakos X, Listing J, Rudwaleit M, Seiper J, Braun J: The relationship between inflammation and new bone formation in patients with ankylosing spondylitis. Arthritis Res Ther. 2008, 10: R104-10.1186/ar2496.
Article
PubMed Central
PubMed
Google Scholar
Maksymowych WP, Chiowchanwisawakit P, Clare T, Pedersen SJ, Østergaard M, Lambert RGW: Inflammatory lesions of the spine on MRI predict the development of new syndesmophytes in ankylosing spondylitis: evidence for coupling between inflammation and ankylosis. Arthritis Rheum. 2009, 60: 93-102. 10.1002/art.24132.
Article
PubMed
Google Scholar
Maksymowych WP: What do biomarkers tell us about the pathogenesis of ankylosing spondylitis?. Arthritis Res Ther. 2009, 11: 101-102. 10.1186/ar2565.
Article
PubMed Central
PubMed
Google Scholar
Baraliakos X, Listing J, Rudwaleit M, Sieper J, Braun J: Evidence for a link between inflammation and new bone formation in ankylosing spondylitis -- a detailed analysis. Ann Rheum Dis. 2008, 67 (Suppl II): 130-
Google Scholar
Heidje van der D, Landewé R, Baraliakos X, Hermann K, Houben H, Hsu B, Baker D, Braun J: MRI-inflammation of the vertebral unit (VU) only marginally contributes to new syndesmophyte formation in that unit: a multi-level analysis. Ann Rheum Dis. 2008, 67 (Suppl II): 130-
Google Scholar