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Erratum to: mPGES-1 null mice are resistant to bleomycin-induced skin fibrosis
Arthritis Research & Therapyvolume 13, Article number: 402 (2011)
The original article was published in Arthritis Research & Therapy 2011 13:R6
Following publication of our recent article , an error in Figure 5d was noticed. In Figure 5d, the β-actin blot corresponding to α-SMA blot was captured on the chemiluminescence imaging system in an inverted orientation. Since this imager does not capture the protein marker, an error in the orientation of the membrane while capturing the picture of the blot occurred. During preparation of the figures for Figure 5d, the α-SMA blot was in right orientation but since orientation of β-actin blot was inverse as it was captured inversely resulted in non-corresponding β-actin blot with respect to α-SMA blot. We have rectified this error now and β-actin blot now corresponds to α-SMA blot. The corrected figure 5 is given here as Figure 1 and a supplementary figure 1 (Additional file 1) showing another set of blots representing Figure 5d is also provided.
McCann MR, Monemdjou R, Fahmi H, Perez G, Liu S, Shi-wen X, Parapuram SK, Kojima F, Denton CP, Abraham DJ, Martel-Pelletier J, Crofford LJ, Leask A, Kapoor M: mPGES-1 null mice are resistant to bleomycin-induced skin fibrosis. Arthritis Res Ther. 2011, 13: R6-10.1186/ar3226.
The online version of the original article can be found at 10.1186/ar3226
Matthew R McCann, Roxana Monemdjou, Andrew Leask and Mohit Kapoor contributed equally to this work.
Electronic supplementary material
Additional file 1: Supplementary Figure 1. mPGES-1 genetic deletion results in reduced α-SMA expression in response to bleomycin treatment. Protein extracts from skin tissue after 4 weeks of bleomycin or PBS treatment were subjected to Western blot analysis with an anti-α-SMA antibody. mPGES-1 null mice treated with bleomycin showed reduced α-SMA expression compared with bleomycin-treated WT mice. Representative blot from four separate animals/group/genotype is shown. (b) Graph represents α-SMA expression normalized to β-actin expression from four separate animals/group/genotype. *P < 0.05; bleomycin-treated WT and mPGES-1 null mice compared with PBS-treated mice. +P < 0.05; bleomycin-treated mPGES-1 null mice compared with bleomycin-treated WT mice. α-SMA, alpha-smooth muscle actin; β-actin, beta-actin; mPGES-1, microsomal prostaglandin E2 synthase-1. (JPEG 37 KB)
Authors’ original submitted files for images
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