United States Bone and Joint Decade: The Burden of Musculoskeletal Diseases in the United States. 2008, Rosemont, IL: American Academy of Orthopaedic Surgeons
Google Scholar
Chitnavis J, Sinsheimer JS, Clipsham K, Loughlin J, Sykes B, Burge PD, Carr AJ: Genetic influences in end-stage osteoarthritis. Sibling risks of hip and knee replacement for idiopathic osteoarthritis. J Bone Joint Surg Br. 1997, 79: 660-664. 10.1302/0301-620X.79B4.7437.
Article
CAS
PubMed
Google Scholar
McDonnell SM, Sinsheimer J, Price AJ, Carr AJ: Genetic influences in the aetiology of anteromedial osteoarthritis of the knee. J Bone Joint Surg Br. 2007, 89: 901-903. 10.1302/0301-620X.89B7.18915.
Article
CAS
PubMed
Google Scholar
Ryder JJ, Garrison K, Song F, Hooper L, Skinner J, Loke Y, Loughlin J, Higgins JP, MacGregor AJ: Genetic associations in peripheral joint osteoarthritis and spinal degenerative disease: a systematic review. Ann Rheum Dis. 2008, 67: 584-591.
Article
CAS
PubMed
Google Scholar
Evangelou E, Chapman K, Meulenbelt I, Karassa FB, Loughlin J, Carr A, Doherty M, Doherty S, Gomez-Reino JJ, Gonzalez A, Halldorsson BV, Hauksson VB, Hofman A, Hart DJ, Ikegawa S, Ingvarsson T, Jiang Q, Jonsdottir I, Jonsson H, Kerkhof HJM, Kloppenburg M, Lane NE, Li J, Lories RJ, van Meurs JBJ, Na"kki A, Nevitt MC, Rodriguez-Lopez J, Shi D, Slagboom E, et al: Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand. Arthritis Rheum. 2009, 60: 1710-1721. 10.1002/art.24524.
Article
PubMed Central
CAS
PubMed
Google Scholar
Chu CR, Beynnon BD, Buckwalter JA, Garrett WE, Katz JN, Rodeo SA, Spindler KP, Stanton RA: Closing the gap between bench and bedside research for early arthritis therapies (EARTH): report from the AOSSM/NIH U-13 Post-Joint Injury Osteoarthritis Conference II. Am J Sports Med. 2011, 39: 1569-1578. 10.1177/0363546511411654.
Article
PubMed Central
PubMed
Google Scholar
Brown TD, Johnston RC, Saltzman CL, Marsh JL, Buckwalter JA: Posttraumatic osteoarthritis: a first estimate of incidence, prevalence, and burden of disease. J Orthop Trauma. 2006, 20: 739-744. 10.1097/01.bot.0000246468.80635.ef.
Article
PubMed
Google Scholar
Gelber AC, Hochberg MC, Mead LA, Wang NY, Wigley FM, Klag MJ: Joint injury in young adults and risk for subsequent knee and hip osteoarthritis. Ann Intern Med. 2000, 133: 321-328.
Article
CAS
PubMed
Google Scholar
Lohmander LS, Englund PM, Dahl LL, Roos EM: The long-term consequences of anterior cruciate ligament and meniscus injures: osteoarthritis. Am J Sports Med. 2007, 35: 1756-1769. 10.1177/0363546507307396.
Article
PubMed
Google Scholar
Altman R, Asch E, Bloch D, Bole G, Borenstein D, Brandt K, Christy W, Cooke TD, Greenwald R, Hochberg M, Howell D, Kaplan D, Koopman W, Longley III S, Mankin H, McShane DJ, Medsger T, Meenan R, Mikkelsen W, Moskowitz R, Murphy W, Rothschild B, Segal M, Sokoloff L, Wolfe F: Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. Arthritis Rheum. 1986, 29: 1039-1049. 10.1002/art.1780290816.
Article
CAS
PubMed
Google Scholar
Services USDoHaH: Clinical Development Programs for Drugs, Devices, and Biological Products Intended for the Treatment of Osteoarthritis (OA). 1999, Rockville, MD: Center for Devices and Radiological Health
Google Scholar
Chu CR, Williams A, Tolliver D, Kwoh CK, Bruno S, Irrgang JJ: Clinical optical coherence tomography of early articular cartilage degeneration in patients with degenerative meniscal tears. Arthritis Rheum. 2010, 62: 1412-1420. 10.1002/art.27378.
Article
PubMed Central
PubMed
Google Scholar
Kieser CW, Jackson RW: Severin Nordentoft: the first arthroscopist. Arthroscopy. 2001, 17: 532-535. 10.1053/jars.2001.24058.
Article
CAS
PubMed
Google Scholar
Outerbridge RE: The etiology of chondromalacia patellae. J Bone Joint Surg Br. 1961, 43-B: 752-757.
CAS
PubMed
Google Scholar
Chu CR, Lin D, Geisler JL, Chu CT, Fu FH, Pan YT: Arthroscopic microscopy of articular cartilage using optical coherence tomography. Am J Sports Med. 2004, 32: 699-709. 10.1177/0363546503261736.
Article
PubMed
Google Scholar
Drexler W, Stamper D, Jesser C, Li XD, Pitris C, Saunders K, Martin S, Lodge MB, Fujimoto JG, Brezinski ME: Correlation of collagen organization with polarization sensitive imaging of in vitro cartilage: implications for osteoarthritis. J Rheumatol. 2001, 28: 1311-1318.
CAS
PubMed
Google Scholar
Chu CR, Izzo NJ, Irrgang JJ, Ferretti M, Studer RK: Clinical diagnosis of potentially treatable early articular cartilage degeneration using optical coherence tomography. J Biomed Opt. 2007, 12: 051703-
Article
PubMed
Google Scholar
O'Malley MJ, Chu CR: Arthroscopic optical coherence tomography in diagnosis of early arthritis. Minim Invasive Surg. 2011, 2011: 671308-
PubMed Central
PubMed
Google Scholar
Bear DM, Szczodry M, Kramer S, Coyle CH, Smolinski P, Chu CR: Optical coherence tomography detection of subclinical traumatic cartilage injury. J Orthop Trauma. 2010, 24: 577-582. 10.1097/BOT.0b013e3181f17a3b.
Article
PubMed Central
PubMed
Google Scholar
Neogi T, Felson D, Niu J, Lynch J, Nevitt M, Guermazi A, Roemer F, Lewis CE, Wallace B, Zhang Y: Cartilage loss occurs in the same subregions as subchondral bone attrition: a within-knee subregion-matched approach from the Multicenter Osteoarthritis Study. Arthritis Rheum. 2009, 61: 1539-1544. 10.1002/art.24824.
Article
PubMed Central
CAS
PubMed
Google Scholar
Felson DT, Lynch J, Guermazi A, Roemer FW, Niu J, McAlindon T, Nevitt MC: Comparison of BLOKS and WORMS scoring systems part II. Longitudinal assessment of knee MRIs for osteoarthritis and suggested approach based on their performance: data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2010, 18: 1402-1407. 10.1016/j.joca.2010.06.016.
Article
PubMed Central
CAS
PubMed
Google Scholar
Peterfy CG, Schneider E, Nevitt M: The osteoarthritis initiative: report on the design rationale for the magnetic resonance imaging protocol for the knee. Osteoarthritis Cartilage. 2008, 16: 1433-1441. 10.1016/j.joca.2008.06.016.
Article
PubMed Central
CAS
PubMed
Google Scholar
Eckstein F, Maschek S, Wirth W, Hudelmaier M, Hitzl W, Wyman B, Nevitt M, Le Graverand MP: One year change of knee cartilage morphology in the first release of participants from the Osteoarthritis Initiative progression subcohort: association with sex, body mass index, symptoms and radiographic osteoarthritis status. Ann Rheum Dis. 2009, 68: 674-679. 10.1136/ard.2008.089904.
Article
PubMed Central
CAS
PubMed
Google Scholar
Bredella MA, Tirman PF, Peterfy CG, Zarlingo M, Feller JF, Bost FW, Belzer JP, Wischer TK, Genant HK: Accuracy of T2-weighted fast spin-echo MR imaging with fat saturation in detecting cartilage defects in the knee: comparison with arthroscopy in 130 patients. AJR Am J Roentgenol. 1999, 172: 1073-1080.
Article
CAS
PubMed
Google Scholar
Potter HG, Foo LF: Magnetic resonance imaging of articular cartilage: trauma, degeneration, and repair. Am J Sports Med. 2006, 34: 661-677. 10.1177/0363546505281938.
Article
PubMed
Google Scholar
Owman H, Tiderius CJ, Neuman P, Nyquist F, Dahlberg LE: Association between findings on delayed gadolinium-enhanced magnetic resonance imaging of cartilage and future knee osteoarthritis. Arthritis Rheum. 2008, 58: 1727-1730. 10.1002/art.23459.
Article
PubMed
Google Scholar
Roos EM, Dahlberg L: Positive effects of moderate exercise on glycosaminoglycan content in knee cartilage: a four-month, randomized, controlled trial in patients at risk of osteoarthritis. Arthritis Rheum. 2005, 52: 3507-3514. 10.1002/art.21415.
Article
CAS
PubMed
Google Scholar
Tiderius CJ, Olsson LE, Leander P, Ekberg O, Dahlberg L: Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) in early knee osteoarthritis. Magn Reson Med. 2003, 49: 488-492. 10.1002/mrm.10389.
Article
PubMed
Google Scholar
Hovis KK, Stehling C, Souza RB, Haughom BD, Baum T, Nevitt M, McCulloch C, Lynch JA, Link TM: Physical activity is associated with magnetic resonance imaging-based knee cartilage T2 measurements in asymptomatic subjects with and those without osteoarthritis risk factors. Arthritis Rheum. 2011, 63: 2248-2256. 10.1002/art.30419.
Article
PubMed Central
PubMed
Google Scholar
Li X, Benjamin Ma C, Link TM, Castillo DD, Blumenkrantz G, Lozano J, Carballido-Gamio J, Ries M, Majumdar S: vivo T(1rho) and T(2) mapping of articular cartilage in osteoarthritis of the knee using 3 T MRI. Osteoarthritis Cartilage. 2007, 15: 789-797. 10.1016/j.joca.2007.01.011.
Article
PubMed Central
CAS
PubMed
Google Scholar
Stahl R, Luke A, Li X, Carballido-Gamio J, Ma CB, Majumdar S, Link TM: T1rho, T2 and focal knee cartilage abnormalities in physically active and sedentary healthy subjects versus early OA patients - a 3.0-Tesla MRI study. Eur Radiol. 2009, 19: 132-143. 10.1007/s00330-008-1107-6.
Article
PubMed
Google Scholar
Du J, Takahashi AM, Chung CB: Ultrashort TE spectroscopic imaging (UTESI): application to the imaging of short T2 relaxation tissues in the musculoskeletal system. J Magn Reson Imaging. 2009, 29: 412-421. 10.1002/jmri.21465.
Article
PubMed
Google Scholar
Williams A, Qian Y, Chu CR: UTE-T2* mapping of human articular cartilage in vivo: a repeatability assessment. Osteoarthritis Cartilage. 2011, 19: 84-88. 10.1016/j.joca.2010.10.018.
Article
PubMed Central
CAS
PubMed
Google Scholar
Williams A, Qian Y, Golla S, Chu CR: UTE-T2* mapping detects sub-clinical meniscus injury after anterior cruciate ligament tear. Osteoarthritis Cartilage. 2012, 20: 486-494. 10.1016/j.joca.2012.01.009.
Article
CAS
PubMed
Google Scholar
Bashir A, Gray ML, Hartke J, Burstein D: Nondestructive imaging of human cartilage glycosaminoglycan concentration by MRI. Magn Reson Med. 1999, 41: 857-865. 10.1002/(SICI)1522-2594(199905)41:5<857::AID-MRM1>3.0.CO;2-E.
Article
CAS
PubMed
Google Scholar
Williams A, Sharma L, McKenzie CA, Prasad PV, Burstein D: Delayed gadolinium-enhanced magnetic resonance imaging of cartilage in knee osteoarthritis: findings at different radiographic stages of disease and relationship to malalignment. Arthritis Rheum. 2005, 52: 3528-3535. 10.1002/art.21388.
Article
CAS
PubMed
Google Scholar
Dardzinski BJ, Mosher TJ, Li S, Van Slyke MA, Smith MB: Spatial variation of T2 in human articular cartilage. Radiology. 1997, 205: 546-550.
Article
CAS
PubMed
Google Scholar
Goodwin DW, Wadghiri YZ, Zhu H, Vinton CJ, Smith ED, Dunn JF: Macroscopic structure of articular cartilage of the tibial plateau: influence of a characteristic matrix architecture on MRI appearance. AJR Am J Roentgenol. 2004, 182: 311-318.
Article
PubMed
Google Scholar
Mosher TJ, Dardzinski BJ, Smith MB: Human articular cartilage: influence of aging and early symptomatic degeneration on the spatial variation of T2 - preliminary findings at 3 T. Radiology. 2000, 214: 259-266.
Article
CAS
PubMed
Google Scholar
Menezes NM, Gray ML, Hartke JR, Burstein D: T2 and T1rho MRI in articular cartilage systems. Magn Reson Med. 2004, 51: 503-509. 10.1002/mrm.10710.
Article
CAS
PubMed
Google Scholar
Williams A, Qian Y, Bear D, Chu CR: Assessing degeneration of human articular cartilage with ultra-short echo time (UTE) T2* mapping. Osteoarthritis Cartilage. 2010, 18: 539-546. 10.1016/j.joca.2010.02.001.
Article
PubMed Central
CAS
PubMed
Google Scholar
Steinbach LS, Suh KJ: Bone marrow edema pattern around the knee on magnetic resonance imaging excluding acute traumatic lesions. Semin Musculoskelet Radiol. 2011, 15: 208-220. 10.1055/s-0031-1278421.
Article
PubMed
Google Scholar
Oda H, Igarashi M, Sase H, Sase T, Yamamoto S: Bone bruise in magnetic resonance imaging strongly correlates with the production of joint effusion and with knee osteoarthritis. J Orthop Sci. 2008, 13: 7-15. 10.1007/s00776-007-1195-1.
Article
PubMed
Google Scholar
Zhao J, Li X, Bolbos RI, Link TM, Majumdar S: Longitudinal assessment of bone marrow edema-like lesions and cartilage degeneration in osteoarthritis using 3 T MR T1rho quantification. Skeletal Radiol. 2010, 39: 523-531. 10.1007/s00256-010-0892-6.
Article
PubMed Central
PubMed
Google Scholar
Crema MD, Roemer FW, Zhu Y, Marra MD, Niu J, Zhang Y, Lynch JA, Javaid MK, Lewis CE, El-Khoury GY, Felson DT, Guermazi A: Subchondral cystlike lesions develop longitudinally in areas of bone marrow edema-like lesions in patients with or at risk for knee osteoarthritis: detection with MR imaging - the MOST study. Radiology. 2010, 256: 855-862. 10.1148/radiol.10091467.
Article
PubMed Central
PubMed
Google Scholar
Kai B, Mann SA, King C, Forster BB: Integrity of articular cartilage on T2 mapping associated with meniscal signal change. Eur J Radiol. 2010, 79: 421-427.
Article
PubMed
Google Scholar
Low AK, Chia MR, Carmody DJ, Lucas P, Hale D: Clinical significance of intrasubstance meniscal lesions on MRI. J Med Imaging Radiat Oncol. 2008, 52: 227-230. 10.1111/j.1440-1673.2008.01951.x.
Article
CAS
PubMed
Google Scholar
Roemer FW, Guermazi A, Hunter DJ, Niu J, Zhang Y, Englund M, Javaid MK, Lynch JA, Mohr A, Torner J, Lewis CE, Nevitt MC, Felson DT: The association of meniscal damage with joint effusion in persons without radiographic osteoarthritis: the Framingham and MOST osteoarthritis studies. Osteoarthritis Cartilage. 2009, 17: 748-753. 10.1016/j.joca.2008.09.013.
Article
PubMed Central
CAS
PubMed
Google Scholar
Haywood L, McWilliams DF, Pearson CI, Gill SE, Ganesan A, Wilson D, Walsh DA: Inflammation and angiogenesis in osteoarthritis. Arthritis Rheum. 2003, 48: 2173-2177. 10.1002/art.11094.
Article
CAS
PubMed
Google Scholar
Smith MD, Triantafillou S, Parker A, Youssef PP, Coleman M: Synovial membrane inflammation and cytokine production in patients with early osteoarthritis. J Rheumatol. 1997, 24: 365-371.
CAS
PubMed
Google Scholar
Myers SL, Brandt KD, Ehlich JW, Braunstein EM, Shelbourne KD, Heck DA, Kalasinski LA: Synovial inflammation in patients with early osteoarthritis of the knee. J Rheumatol. 1990, 17: 1662-1669.
CAS
PubMed
Google Scholar
Scanzello CR, McKeon B, Swaim BH, DiCarlo E, Asomugha EU, Kanda V, Nair A, Lee DM, Richmond JC, Katz JN, Crow MK, Goldring SR: Synovial inflammation in patients undergoing arthroscopic meniscectomy: molecular characterization and relationship to symptoms. Arthritis Rheum. 2011, 63: 391-400. 10.1002/art.30137.
Article
PubMed Central
PubMed
Google Scholar
Baker K, Grainger A, Niu J, Clancy M, Guermazi A, Crema M, Hughes L, Buckwalter J, Wooley A, Nevitt M, Felson DT: Relation of synovitis to knee pain using contrast-enhanced MRIs. Ann Rheum Dis. 2010, 69: 1779-1783. 10.1136/ard.2009.121426.
Article
CAS
PubMed
Google Scholar
Roemer FW, Guermazi A, Felson DT, Niu J, Nevitt MC, Crema MD, Lynch JA, Lewis CE, Torner J, Zhang Y: Presence of MRI-detected joint effusion and synovitis increases the risk of cartilage loss in knees without osteoarthritis at 30-month follow-up: the MOST study. Ann Rheum Dis. 2011, 70: 1804-1809. 10.1136/ard.2011.150243.
Article
PubMed Central
PubMed
Google Scholar
Han CW, Chu CR, Adachi N, Usas A, Fu FH, Huard J, Pan Y: Analysis of rabbit articular cartilage repair after chondrocyte implantation using optical coherence tomography. Osteoarthritis Cartilage. 2003, 11: 111-121. 10.1053/joca.2002.0862.
Article
CAS
PubMed
Google Scholar
Ugryumova N, Jacobs J, Bonesi M, Matcher SJ: Novel optical imaging technique to determine the 3-D orientation of collagen fibers in cartilage: variable-incidence angle polarization-sensitive optical coherence tomography. Osteoarthritis Cartilage. 2009, 17: 33-42. 10.1016/j.joca.2008.05.005.
Article
CAS
PubMed
Google Scholar
Mlynarik V, Trattnig S, Huber M, Zembsch A, Imhof H: The role of relaxation times in monitoring proteoglycan depletion in articular cartilage. J Magn Reson Imaging. 1999, 10: 497-502. 10.1002/(SICI)1522-2586(199910)10:4<497::AID-JMRI1>3.0.CO;2-T.
Article
CAS
PubMed
Google Scholar
Nieminen MT, Rieppo J, Silvennoinen J, Toyras J, Hakumaki JM, Hyttinen MM, Helminen HJ, Jurvelin JS: Spatial assessment of articular cartilage proteoglycans with Gd-DTPA-enhanced T1 imaging. Magn Reson Med. 2002, 48: 640-648. 10.1002/mrm.10273.
Article
CAS
PubMed
Google Scholar
Akella SV, Regatte RR, Gougoutas AJ, Borthakur A, Shapiro EM, Kneeland JB, Leigh JS, Reddy R: Proteoglycan-induced changes in T1rho-relaxation of articular cartilage at 4T. Magn Reson Med. 2001, 46: 419-423. 10.1002/mrm.1208.
Article
CAS
PubMed
Google Scholar
Bear DM, Williams A, Chu CT, Coyle CH, Chu CR: Optical coherence tomography grading correlates with MRI T2 mapping and extracellular matrix content. J Orthopaedic Res. 2010, 28: 546-552.
Google Scholar
Xia Y, Moody JB, Burton-Wurster N, Lust G: Quantitative in situ correlation between microscopic MRI and polarized light microscopy studies of articular cartilage. Osteoarthritis Cartilage. 2001, 9: 393-406. 10.1053/joca.2000.0405.
Article
CAS
PubMed
Google Scholar
Li W, Scheidegger R, Wu Y, Edelman RR, Farley M, Krishnan N, Burstein D, Prasad PV: Delayed contrast-enhanced MRI of cartilage: comparison of nonionic and ionic contrast agents. Magn Reson Med. 2010, 64: 1267-1273. 10.1002/mrm.22555.
Article
CAS
PubMed
Google Scholar
Henkelman RM, Stanisz GJ, Menezes N, Burstein D: Can MTR be used to assess cartilage in the presence of Gd-DTPA2-?. Magn Reson Med. 2002, 48: 1081-1084. 10.1002/mrm.10322.
Article
CAS
PubMed
Google Scholar
Matyas JR, Atley L, Ionescu M, Eyre DR, Poole AR: Analysis of cartilage biomarkers in the early phases of canine experimental osteoarthritis. Arthritis Rheum. 2004, 50: 543-552. 10.1002/art.20027.
Article
CAS
PubMed
Google Scholar
Heard BJ, Achari Y, Chung M, Shrive NG, Frank CB: Early joint tissue changes are highly correlated with a set of inflammatory and degradative synovial biomarkers after ACL autograft and its sham surgery in an ovine model. J Orthop Res. 2011, 29: 1185-1192. 10.1002/jor.21404.
Article
PubMed
Google Scholar
Kraus VB: Osteoarthritis year 2010 in review: biochemical markers. Osteoarthritis Cartilage. 2011, 19: 346-353. 10.1016/j.joca.2011.02.002.
Article
PubMed Central
CAS
PubMed
Google Scholar
Patra D, Sandell LJ: Recent advances in biomarkers in osteoarthritis. Curr Opin Rheumatol. 2011, 23: 465-470. 10.1097/BOR.0b013e328349a32b.
Article
CAS
PubMed
Google Scholar
Cameron ML, Fu FH, Paessler HH, Schneider M, Evans CH: Synovial fluid cytokine concentrations as possible prognostic indicators in the ACL-deficient knee. Knee Surg Sports Traumatol Arthrosc. 1994, 2: 38-44. 10.1007/BF01552652.
Article
CAS
PubMed
Google Scholar
Irie K, Uchiyama E, Iwaso H: Intraarticular inflammatory cytokines in acute anterior cruciate ligament injured knee. Knee. 2003, 10: 93-96. 10.1016/S0968-0160(02)00083-2.
Article
PubMed
Google Scholar
Catterall JB, Stabler TV, Flannery CR, Kraus VB: Changes in serum and synovial fluid biomarkers after acute injury (NCT00332254). Arthritis Res Ther. 2010, 12: R229-10.1186/ar3216.
Article
PubMed Central
PubMed
Google Scholar
Cuellar VG, Cuellar JM, Golish SR, Yeomans DC, Scuderi GJ: Cytokine profiling in acute anterior cruciate ligament injury. Arthroscopy. 2010, 26: 1296-1301. 10.1016/j.arthro.2010.02.011.
Article
PubMed
Google Scholar
Cuellar JM, Scuderi GJ, Cuellar VG, Golish SR, Yeomans DC: Diagnostic utility of cytokine biomarkers in the evaluation of acute knee pain. J Bone Joint Surg Am. 2009, 91: 2313-2320. 10.2106/JBJS.H.00835.
Article
PubMed
Google Scholar
Hollander AP, Heathfi eld TF, Webber C, Iwata Y, Bourne R, Rorabeck C, Poole AR: Increased damage to type II collagen in osteoarthritic articular cartilage detected by a new immunoassay. J Clin Invest. 1994, 93: 1722-1732. 10.1172/JCI117156.
Article
PubMed Central
CAS
PubMed
Google Scholar
Lohmander LS, Ionescu M, Jugessur H, Poole AR: Changes in joint cartilage aggrecan after knee injury and in osteoarthritis. Arthritis Rheum. 1999, 42: 534-544. 10.1002/1529-0131(199904)42:3<534::AID-ANR19>3.0.CO;2-J.
Article
CAS
PubMed
Google Scholar
Witter J, Roughley PJ, Webber C, Roberts N, Keystone E, Poole AR: The immunologic detection and characterization of cartilage proteoglycan degradation products in synovial fluids of patients with arthritis. Arthritis Rheum. 1987, 30: 519-529. 10.1002/art.1780300506.
Article
CAS
PubMed
Google Scholar
Struglics A, Hansson M, Lohmander LS: Human aggrecanase generated synovial fluid fragment levels are elevated directly after knee injuries due to proteolysis both in the inter globular and chondroitin sulfate domains. Osteoarthritis Cartilage. 2011, 19: 1047-1057. 10.1016/j.joca.2011.05.006.
Article
CAS
PubMed
Google Scholar
Larsson S, Lohmander LS, Struglics A: Synovial fluid level of aggrecan ARGS fragments is a more sensitive marker of joint disease than glycosaminoglycan or aggrecan levels: a cross-sectional study. Arthritis Res Ther. 2009, 11: R92-10.1186/ar2735.
Article
PubMed Central
PubMed
Google Scholar
Pruksakorn D, Rojanasthien S, Pothacharoen P, Luevitoonvechkij S, Wongtreratanachai P, Ong-Chai S, Kongtawelert P: Chondroitin sulfate epitope (WF6) and hyaluronic acid as serum markers of cartilage degeneration in patients following anterior cruciate ligament injury. J Sci Med Sport. 2009, 12: 445-448. 10.1016/j.jsams.2008.02.003.
Article
PubMed
Google Scholar