|
Associated haplotypes
|
Frequency
|
EM algorithm*
|
Logistic regression
|
Logistic regression
|
|---|
|
(rs27037 + rs27980 + rs27044)
|
AS
|
Normal
|
P -value
|
P -value
|
OR (95% CI)
|
(sex adjusted)
|
|---|
| | | | | | |
P -value
|
OR (95% CI)
|
|---|
|
GCC
|
0.085
|
0.119
|
9 × 10-3
|
7 × 10-4
|
0.69 (0.55-0.85)
|
1.9 × 10-3
|
0.69 (0.55-0.87)
|
|
TAG
|
0.008
|
0.012
|
2.6 × 10-3
|
3.9 × 10-3
|
0.21 (0.07-0.61)
|
4.3 × 10-3
|
0.21 (0.07-0.61)
|
|
TCG
|
0.475
|
0.399
|
<0.00001
|
<0.00001
|
1.36 (1.12-1.55)
|
<0.00001
|
1.38 (1.12-1.58)
|
- *The p-values for the estimated haplotypes were generated from 10,000 permutations.
