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Table 1 Characteristics of SLE patients and healthy controls studied

From: Hydroxychloroquine is associated with impaired interferon-alpha and tumor necrosis factor-alpha production by plasmacytoid dendritic cells in systemic lupus erythematosus

 

Healthy

SLE subjects

 

(n= 10)

All (n= 39)

HCQ

(n= 25)

No HCQ

(n= 14)

Age, years (SD)

30 (4.3)1

53 (12.5)1

50.4 (12.7)

57.6 (11.2)

Female, n (%)

8 (80%)

36 (92%)

22 (88%)

14 (100%)

European ancestry, n (%)

10 (100%)

39 (100%)

25 (100%)

14 (100%)

Years since SLE diagnosis (SD)

 

19.2 (9.7)

17.2 (9.4)

22.7 (9.6)

SLE activity (SLAQ)

 

10.4 (8.4)

11.8 (8.9)

8.1 (7.3)

Treatment

    

prednisone, n (%)

 

12 (30.8%)

9 (36%)

3 (21.4%)

immunosuppressant, n (%)

 

8 (20.5)

5 (20%)

3 (21.4%)

  1. 1, P < 0.0001. HCQ, hydroxycholoroquine; SD, standard deviation; SLAQ, Systemic Lupus Activity Questionnaire; SLE, systemic lupus erythematosus