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Supplementary Table 1 Affinity data of the anti-CD4 mAb

From: Differential clinical efficacy of anti-CD4 monoclonal antibodies in rat adjuvant arthritis is paralleled by differential influence on NF-κB binding activity and TNF-α secretion of T cells

Anti-CD4 mAb kass (M s-1) kdiss (s-1) KA (M-1)
W3/25 4.7 × 105 1.0 × 10-4 4.9 × 109
OX35 0.8 × 105 0.8 × 10-3 1.0 × 108
RIB5/2 2.7 × 105 3.7 × 10-3 0.7 × 108
  1. kass = association rate constant; kdiss = dissociation rate constant; KA = affinity constant (kass/kdiss).