Skip to main content

Supplementary Table 1 Affinity data of the anti-CD4 mAb

From: Differential clinical efficacy of anti-CD4 monoclonal antibodies in rat adjuvant arthritis is paralleled by differential influence on NF-κB binding activity and TNF-α secretion of T cells

Anti-CD4 mAb

kass (M s-1)

kdiss (s-1)

KA (M-1)

W3/25

4.7 × 105

1.0 × 10-4

4.9 × 109

OX35

0.8 × 105

0.8 × 10-3

1.0 × 108

RIB5/2

2.7 × 105

3.7 × 10-3

0.7 × 108

  1. kass = association rate constant; kdiss = dissociation rate constant; KA = affinity constant (kass/kdiss).
Back to article page

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us