Ravetch JV, Clynes RA: Divergent roles for Fc receptors and complement in vivo. Annu Rev Immunol. 1998, 16: 421-432. 10.1146/annurev.immunol.16.1.421.
Article
CAS
PubMed
Google Scholar
Baumann U, Kohl J, Tschernig T, Schwerter-Strumpf K, Verbeek JS, Schmidt RE, Gessner JE: A codominant role of Fc gamma RI/III and C5aR in the reverse Arthus reaction. J Immunol. 2000, 164: 1065-1070.
Article
CAS
PubMed
Google Scholar
Sylvestre D, Clynes R, Ma M, Warren H, Carroll MC, Ravetch JV: Immunoglobulin G-mediated inflammatory responses develop normally in complement-deficient mice. J Exp Med. 1996, 184: 2385-2392. 10.1084/jem.184.6.2385.
Article
PubMed Central
CAS
PubMed
Google Scholar
Nimmerjahn F, Ravetch JV: FcgammaRs in health and disease. Curr Top Microbiol Immunol. 2011, 350: 105-125.
CAS
PubMed
Google Scholar
Walport MJ: Complement. Second of two parts. N Engl J Med. 2001, 344: 1140-1144. 10.1056/NEJM200104123441506.
Article
CAS
PubMed
Google Scholar
Walport MJ: Complement. First of two parts. N Engl J Med. 2001, 344: 1058-1066. 10.1056/NEJM200104053441406.
Article
CAS
PubMed
Google Scholar
Kitamura H, Matsumoto M, Nagaki K: C3-independent immune haemolysis: haemolysis of EAC14oxy2 cells by C5-C9 without participation of C3. Immunology. 1984, 53: 575-582.
PubMed Central
CAS
PubMed
Google Scholar
Salama A, Bhakdi S, Mueller-Eckhardt C: Evidence suggesting the occurrence of C3-independent intravascular immune hemolysis. Reactive hemolysis in vivo. Transfusion. 1987, 27: 49-53. 10.1046/j.1537-2995.1987.27187121473.x.
Article
CAS
PubMed
Google Scholar
Huber-Lang M, Sarma JV, Zetoune FS, Rittirsch D, Neff TA, McGuire SR, Lambris JD, Warner RL, Flierl MA, Hoesel LM, Gebhard F, Younger JG, Drouin SM, Wetsel RA, Ward PA: Generation of C5a in the absence of C3: a new complement activation pathway. Nat Med. 2006, 12: 682-687. 10.1038/nm1419.
Article
CAS
PubMed
Google Scholar
Girardi G, Redecha P, Salmon JE: Heparin prevents antiphospholipid antibody-induced fetal loss by inhibiting complement activation. Nat Med. 2004, 10: 1222-1226. 10.1038/nm1121.
Article
CAS
PubMed
Google Scholar
Yu G, Sun Y, Foerster K, Manuel J, Molina H, Levy GA, Gorczynski RM, Clark DA: LPS-induced murine abortions require C5 but not C3, and are prevented by upregulating expression of the CD200 tolerance signaling molecule. Am J Reprod Immunol. 2008, 60: 135-140. 10.1111/j.1600-0897.2008.00605.x.
Article
PubMed
Google Scholar
Amara U, Flierl MA, Rittirsch D, Klos A, Chen H, Acker B, Bruckner UB, Nilsson B, Gebhard F, Lambris JD, Huber-Lang M: Molecular intercommunication between the complement and coagulation systems. J Immunol. 2010, 185: 5628-5636. 10.4049/jimmunol.0903678.
Article
PubMed Central
CAS
PubMed
Google Scholar
Kumar V, Ali SR, Konrad S, Zwirner J, Verbeek JS, Schmidt RE, Gessner JE: Cell-derived anaphylatoxins as key mediators of antibody-dependent type II autoimmunity in mice. J Clin Invest. 2006, 116: 512-520. 10.1172/JCI25536.
Article
PubMed Central
CAS
PubMed
Google Scholar
Syed SN, Konrad S, Wiege K, Nieswandt B, Nimmerjahn F, Schmidt RE, Gessner JE: Both FcgammaRIV and FcgammaRIII are essential receptors mediating type II and type III autoimmune responses via FcRgamma-LAT-dependent generation of C5a. Eur J Immunol. 2009, 39: 3343-3356. 10.1002/eji.200939884.
Article
CAS
PubMed
Google Scholar
Baumann U, Chouchakova N, Gewecke B, Kohl J, Carroll MC, Schmidt RE, Gessner JE: Distinct tissue site-specific requirements of mast cells and complement components C3/C5a receptor in IgG immune complex-induced injury of skin and lung. J Immunol. 2001, 167: 1022-1027.
Article
CAS
PubMed
Google Scholar
Kouskoff V, Korganow AS, Duchatelle V, Degott C, Benoist C, Mathis D: Organ-specific disease provoked by systemic autoimmunity. Cell. 1996, 87: 811-822. 10.1016/S0092-8674(00)81989-3.
Article
CAS
PubMed
Google Scholar
Matsumoto I, Staub A, Benoist C, Mathis D: Arthritis provoked by linked T and B cell recognition of a glycolytic enzyme. Science. 1999, 286: 1732-1735. 10.1126/science.286.5445.1732.
Article
CAS
PubMed
Google Scholar
Korganow AS, Ji H, Mangialaio S, Duchatelle V, Pelanda R, Martin T, Degott C, Kikutani H, Rajewsky K, Pasquali JL, Benoist C, Mathis D: From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins. Immunity. 1999, 10: 451-461. 10.1016/S1074-7613(00)80045-X.
Article
CAS
PubMed
Google Scholar
Corr M, Crain B: The role of FcgammaR signaling in the K/B × N serum transfer model of arthritis. J Immunol. 2002, 169: 6604-6609.
Article
CAS
PubMed
Google Scholar
Ji H, Ohmura K, Mahmood U, Lee DM, Hofhuis FM, Boackle SA, Takahashi K, Holers VM, Walport M, Gerard C, Ezekowitz A, Carroll MC, Brenner M, Weissleder R, Verbeek JS, Duchatelle V, Degott C, Benoist C, Mathis D: Arthritis critically dependent on innate immune system players. Immunity. 2002, 16: 157-168. 10.1016/S1074-7613(02)00275-3.
Article
CAS
PubMed
Google Scholar
Ji H, Gauguier D, Ohmura K, Gonzalez A, Duchatelle V, Danoy P, Garchon HJ, Degott C, Lathrop M, Benoist C, Mathis D: Genetic influences on the end-stage effector phase of arthritis. J Exp Med. 2001, 194: 321-330. 10.1084/jem.194.3.321.
Article
PubMed Central
CAS
PubMed
Google Scholar
Binstadt BA, Hebert JL, Ortiz-Lopez A, Bronson R, Benoist C, Mathis D: The same systemic autoimmune disease provokes arthritis and endocarditis via distinct mechanisms. Proc Natl Acad Sci USA. 2009, 106: 16758-16763. 10.1073/pnas.0909132106.
Article
PubMed Central
CAS
PubMed
Google Scholar
Wetsel RA, Fleischer DT, Haviland DL: Deficiency of the murine fifth complement component (C5). A 2-base pair gene deletion in a 5'-exon. J Biol Chem. 1990, 265: 2435-2440.
CAS
PubMed
Google Scholar
Wessels MR, Butko P, Ma M, Warren HB, Lage AL, Carroll MC: Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity. Proc Natl Acad Sci USA. 1995, 92: 11490-11494. 10.1073/pnas.92.25.11490.
Article
PubMed Central
CAS
PubMed
Google Scholar
Takai T, Li M, Sylvestre D, Clynes R, Ravetch JV: FcR gamma chain deletion results in pleiotrophic effector cell defects. Cell. 1994, 76: 519-529. 10.1016/0092-8674(94)90115-5.
Article
CAS
PubMed
Google Scholar
Frei Y, Lambris JD, Stockinger B: Generation of a monoclonal antibody to mouse C5 application in an ELISA assay for detection of anti-C5 antibodies. Mol Cell Probes. 1987, 1: 141-149. 10.1016/0890-8508(87)90022-3.
Article
CAS
PubMed
Google Scholar
Schulze EB, Hedley BD, Goodale D, Postenka CO, Al-Katib W, Tuck AB, Chambers AF, Allan AL: The thrombin inhibitor Argatroban reduces breast cancer malignancy and metastasis via osteopontin-dependent and osteopontin-independent mechanisms. Breast Cancer Res Treat. 2008, 112: 243-254. 10.1007/s10549-007-9865-4.
Article
CAS
PubMed
Google Scholar
Asanuma K, Wakabayashi H, Hayashi T, Okuyama N, Seto M, Matsumine A, Kusuzaki K, Suzuki K, Uchida A: Thrombin inhibitor, argatroban, prevents tumor cell migration and bone metastasis. Oncology. 2004, 67: 166-173. 10.1159/000081004.
Article
CAS
PubMed
Google Scholar
Tsao PY, Arora V, Ji MQ, Wright AC, Eisenberg RA: KRN/I-Ag7 mouse arthritis is independent of complement C3. J Clin Immunol. 2011, 31: 857-863. 10.1007/s10875-011-9562-2.
Article
PubMed Central
CAS
PubMed
Google Scholar
Kim TS, Park M, Nepomuceno RR, Palmarini G, Winokur S, Cotman CA, Bengtsson U, Tenner AJ: Characterization of the murine homolog of C1qR(P): identical cellular expression pattern, chromosomal location and functional activity of the human and murine C1qR(P). Mol Immunol. 2000, 37: 377-389. 10.1016/S0161-5890(00)00057-2.
Article
CAS
PubMed
Google Scholar
Hashimoto M, Hirota K, Yoshitomi H, Maeda S, Teradaira S, Akizuki S, Prieto-Martin P, Nomura T, Sakaguchi N, Kohl J, Heyman B, Takahashi M, Fujita T, Mimori T, Sakaguchi S: Complement drives Th17 cell differentiation and triggers autoimmune arthritis. J Exp Med. 2010, 207: 1135-1143. 10.1084/jem.20092301.
Article
PubMed Central
CAS
PubMed
Google Scholar
Jacobs JP, Wu HJ, Benoist C, Mathis D: IL-17-producing T cells can augment autoantibody-induced arthritis. Proc Natl Acad Sci USA. 2009, 106: 21789-21794. 10.1073/pnas.0912152106.
Article
PubMed Central
CAS
PubMed
Google Scholar
Wu HJ, Ivanov II, Darce J, Hattori K, Shima T, Umesaki Y, Littman DR, Benoist C, Mathis D: Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells. Immunity. 2010, 32: 815-827. 10.1016/j.immuni.2010.06.001.
Article
PubMed Central
CAS
PubMed
Google Scholar
Foerster K, He W, Manuel J, Bartczak A, Liu M, Markert UR, Levy GA, Clark DA: LPS-induced occult loss in mice requires FGL2. Am J Reprod Immunol. 2007, 58: 524-529. 10.1111/j.1600-0897.2007.00543.x.
Article
PubMed
Google Scholar
Marty I, Peclat V, Kirdaite G, Salvi R, So A, Busso N: Amelioration of collagen-induced arthritis by thrombin inhibition. J Clin Invest. 2001, 107: 631-640. 10.1172/JCI11064.
Article
PubMed Central
CAS
PubMed
Google Scholar
Krisinger MJ, Goebeler V, Lu Z, Meixner SC, Myles T, Pryzdial EL, Conway EM: Thrombin generates previously unidentified C5 products that support the terminal complement activation pathway. Blood. 2012, 120: 1717-1725. 10.1182/blood-2012-02-412080.
Article
CAS
PubMed
Google Scholar
Thiagarajan P, Dannenbring R, Matsuura K, Tramontano A, Gololobov G, Paul S: Monoclonal antibody light chain with prothrombinase activity. Biochemistry. 2000, 39: 6459-6465. 10.1021/bi992588w.
Article
CAS
PubMed
Google Scholar
Woodruff TM, Nandakumar KS, Tedesco F: Inhibiting the C5-C5a receptor axis. Mol Immunol. 2011, 48: 1631-1642. 10.1016/j.molimm.2011.04.014.
Article
CAS
PubMed
Google Scholar
Fischetti F, Durigutto P, Macor P, Marzari R, Carretta R, Tedesco F: Selective therapeutic control of C5a and the terminal complement complex by anti-C5 single-chain Fv in an experimental model of antigen-induced arthritis in rats. Arthritis Rheum. 2007, 56: 1187-1197. 10.1002/art.22492.
Article
CAS
PubMed
Google Scholar