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Table 1 Clinical manifestations and laboratory data of DM patients, PM patients, and controls

From: The roles of neutrophil serine proteinases in idiopathic inflammatory myopathies

Clinical characteristic NC (n = 39) DM (n = 48) PM (n = 16) P valuea
DM vs NC PM vs NC DM vs PM
Age, mean ± SD 48.87 ± 12.40 50.25 ± 11.97 44.41 ± 11.99 0.606 0.2170 0.0889
Sex (male/female) 9/30 11/37 6/10 0.986 0.275 0.253
Disease duration (months) 15.41 ± 21.34 23.00 ± 34.25 0.3138
CK (U/L)b 842.46 ± 1969.14 4368.46 ± 7149.77 0.061
LDH (U/L)c 409.43 ± 267.63 612.02 ± 432.16 0.032*
ESR (mm/h)d 57.93 ± 95.67 43.29 ± 34.00 0.542
CRP (mg/L)e 14.92 ± 20.72 12.99 ± 23.47 0.766
IgA (mg/L)f 2625.22 ± 1408.36 2660.25 ± 1308.82 0.932
IgM (mg/L)g 1848.37 ± 1546.84 1715.38 ± 874.10 0.748
IgG (g/L)h 29.58 ± 98.34 16.70 ± 7.69 0.616
C3 (mg/l)u 888.65 ± 238.43 967.25 ± 319.90 0.318
C4 (mg/l)j 243.07 ± 127.62 299.75 ± 347.79 0.534
Jo-1 (positive/negative) 11/37 5/11 0.505
Ro-52 (positive/negative) 16/32 2/14 0.108
ILD (yes/no) 23/23 3/13 0.029*
Prednisone (yes/no) 46/2 16/0 0.407
Cyclophosphamide (yes/no) 6/42 1/15 0.488
Methotrexate (yes/no) 8/40 5/11 0.209
Azathioprine (yes/no) 9/39 5/11 0.295
Mycophenolate mofetil (yes/no) 4/40 0/16 0.212
Thalidomide (yes/no) 25/23 1/15 0.001*
Hydroxychloroquine (yes/no) 29/19 4/12 0.014*
Total glucosides of Paeonia (yes/no) 16/32 7/9 0.452
  1. There were no significant differences in age and gender between NC, DM patients, and PM patients
  2. NC normal controls, DM dermatomyositis, PM polymyositis, SD standard deviation
  3. at test, *P < 0.05 significant
  4. bNormal range of creatine kinase (CK): 40–200 U/L
  5. cNormal range of lactate dehydrogenase (LDH): 120–250 U/L
  6. dNormal range of erythrocyte sedimentation rate (ESR): 0–20 mm/h
  7. eNormal range of C-reactive protein (CRP): 0–8 mg/L
  8. fNormal range of immunoglobulin A (IgA): 690–3820 mg/L
  9. gNormal range of immunoglobulin M (IgM): 630–2770 mg/L
  10. hNormal range of immunoglobulin G (IgG): 7.23–16.85 g/L
  11. iNormal range of complement component 3 (C3): 850–1930 mg/L
  12. jNormal range of complement component 4 (C4): 120–360 mg/L