Tieu J, Lundberg IE, Limaye V. Idiopathic inflammatory myositis. Best Pract Res Clin Rheumatol. 2016;30(1):149–68.
Article
PubMed
Google Scholar
Gao S, Luo H, Zhang H, Zuo X, Wang L, Zhu H. Using multi-omics methods to understand dermatomyositis/polymyositis. Autoimmun Rev. 2017;16(10):1044–8.
Article
PubMed
CAS
Google Scholar
Dimachkie MM, Barohn RJ, Amato AA. Idiopathic inflammatory myopathies. Neurol Clin. 2014;32(3):595–628. vii
Article
PubMed
PubMed Central
Google Scholar
Mammen AL. Autoimmune myopathies: autoantibodies, phenotypes and pathogenesis. Nat Rev Neurol. 2011;7(6):343–54.
Article
PubMed
CAS
Google Scholar
Ernste FC, Reed AM. Idiopathic inflammatory myopathies: current trends in pathogenesis, clinical features, and up-to-date treatment recommendations. Mayo Clin Proc. 2013;88(1):83–105.
Article
PubMed
Google Scholar
Nagaraju K, Lundberg IE. Polymyositis and dermatomyositis: pathophysiology. Rheum Dis Clin N Am. 2011;37(2):159–171, v.
Article
Google Scholar
Luo YB, Mastaglia FL. Dermatomyositis, polymyositis and immune-mediated necrotising myopathies. Biochim Biophys Acta. 2015;1852(4):622–32.
Article
PubMed
CAS
Google Scholar
Grundtman C, Malmstrom V, Lundberg IE. Immune mechanisms in the pathogenesis of idiopathic inflammatory myopathies. Arthritis Res Ther. 2007;9(2):208.
Article
PubMed
PubMed Central
CAS
Google Scholar
Day J, Otto S, Proudman S, Hayball JD, Limaye V. Dysregulated innate immune function in the aetiopathogenesis of idiopathic inflammatory myopathies. Autoimmun Rev. 2017;16(1):87–95.
Article
PubMed
CAS
Google Scholar
Rostasy KM, Piepkorn M, Goebel HH, Menck S, Hanefeld F, Schulz-Schaeffer WJ. Monocyte/macrophage differentiation in dermatomyositis and polymyositis. Muscle Nerve. 2004;30(2):225–30.
Article
PubMed
Google Scholar
Zong M, Lundberg IE. Pathogenesis, classification and treatment of inflammatory myopathies. Nat Rev Rheumatol. 2011;7(5):297–306.
Article
PubMed
CAS
Google Scholar
Heutinck KM, ten Berge IJ, Hack CE, Hamann J, Rowshani AT. Serine proteases of the human immune system in health and disease. Mol Immunol. 2010;47(11–12):1943–55.
Article
PubMed
CAS
Google Scholar
Pham CT. Neutrophil serine proteases fine-tune the inflammatory response. Int J Biochem Cell Biol. 2008;40(6–7):1317–33.
Article
PubMed
CAS
Google Scholar
Korkmaz B, Horwitz MS, Jenne DE, Gauthier F. Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases. Pharmacol Rev. 2010;62(4):726–59.
Article
PubMed
PubMed Central
CAS
Google Scholar
Cohen-Mazor M, Mazor R, Kristal B, Sela S. Elastase and cathepsin G from primed leukocytes cleave vascular endothelial cadherin in hemodialysis patients. Biomed Res Int. 2014;2014:459640.
Article
PubMed
PubMed Central
CAS
Google Scholar
Woo MM, Patterson EK, Clarson C, Cepinskas G, Bani-Yaghoub M, Stanimirovic DB, Fraser DD. Elevated leukocyte azurophilic enzymes in human diabetic ketoacidosis plasma degrade cerebrovascular endothelial junctional proteins. Crit Care Med. 2016;44(9):e846–53.
Article
PubMed
Google Scholar
Jerke U, Hernandez DP, Beaudette P, Korkmaz B, Dittmar G, Kettritz R. Neutrophil serine proteases exert proteolytic activity on endothelial cells. Kidney Int. 2015;88(4):764–75.
Article
PubMed
CAS
Google Scholar
Edens HA, Parkos CA. Neutrophil transendothelial migration and alteration in vascular permeability: focus on neutrophil-derived azurocidin. Curr Opin Hematol. 2003;10(1):25–30.
Article
PubMed
CAS
Google Scholar
Chertov O, Ueda H, Xu LL, Tani K, Murphy WJ, Wang JM, Howard OM, Sayers TJ, Oppenheim JJ. Identification of human neutrophil-derived cathepsin G and azurocidin/CAP37 as chemoattractants for mononuclear cells and neutrophils. J Exp Med. 1997;186(5):739–47.
Article
PubMed
PubMed Central
CAS
Google Scholar
Zhu H, Mi W, Luo H, Chen T, Liu S, Raman I, Zuo X, Li QZ. Whole-genome transcription and DNA methylation analysis of peripheral blood mononuclear cells identified aberrant gene regulation pathways in systemic lupus erythematosus. Arthritis Res Ther. 2016;18:162.
Article
PubMed
PubMed Central
CAS
Google Scholar
Bohan A, Peter JB. Polymyositis and dermatomyositis (first of two parts). N Engl J Med. 1975;292(7):344–7.
Article
PubMed
CAS
Google Scholar
Bohan A, Peter JB. Polymyositis and dermatomyositis (second of two parts). N Engl J Med. 1975;292(8):403–7.
Article
PubMed
CAS
Google Scholar
Gao S, Zhu H, Yang H, Zhang H, Li Q, Luo H. The role and mechanism of cathepsin G in dermatomyositis. Biomed Pharmacother. 2017;94:697–704.
Article
PubMed
CAS
Google Scholar
Zhou B, Zhu H, Luo H, Gao S, Dai X, Li Y, Zuo X. MicroRNA-202-3p regulates scleroderma fibrosis by targeting matrix metalloproteinase 1. Biomed Pharmacother. 2017;87:412–8.
Article
PubMed
CAS
Google Scholar
Zhou B, Zuo XX, Li YS, Gao SM, Dai XD, Zhu HL, Luo H. Integration of microRNA and mRNA expression profiles in the skin of systemic sclerosis patients. Sci Rep. 2017;7:42899.
Article
PubMed
PubMed Central
CAS
Google Scholar
Ama PF, Simoneau JA, Boulay MR, Serresse O, Theriault G, Bouchard C. Skeletal muscle characteristics in sedentary black and Caucasian males. J Appl Physiol. 1986;61(5):1758–61.
Article
PubMed
CAS
Google Scholar
Volochayev R, Csako G, Wesley R, Rider LG, Miller FW. Laboratory test abnormalities are common in polymyositis and dermatomyositis and differ among clinical and demographic groups. Open Rheumatol J. 2012;6:54–63.
Article
PubMed
PubMed Central
Google Scholar
Zaba LC, Fiorentino DF. Skin disease in dermatomyositis. Curr Opin Rheumatol. 2012;24(6):597–601.
Article
PubMed
Google Scholar
Oldroyd A, Lilleker J, Chinoy H. Idiopathic inflammatory myopathies—a guide to subtypes, diagnostic approach and treatment. Clin Med. 2017;17(4):322–8.
Article
Google Scholar
Wu JJ, Huang DB, Pang KR, Hsu S, Tyring SK. Thalidomide: dermatological indications, mechanisms of action and side-effects. Br J Dermatol. 2005;153(2):254–73.
Article
PubMed
CAS
Google Scholar
Sebastiani M, Puccini R, Manfredi A, Manni E, Colaci M, Mattei P, Barachini P, Ferri C. Staphylococcus protein A-based extracorporeal immunoadsorption and thalidomide in the treatment of skin manifestation of dermatomyositis: a case report. Therapeutic Apheresis Dialysis. 2009;13(3):225–8.
Article
PubMed
CAS
Google Scholar
Anic B, Cerovec M. Polymyositis/dermatomyositis--clinical picture and treatment. Reumatizam. 2012;59(2):44–50.
PubMed
Google Scholar
Owen CA, Campbell EJ. The cell biology of leukocyte-mediated proteolysis. J Leukoc Biol. 1999;65(2):137–50.
Article
PubMed
CAS
Google Scholar
Bank U, Ansorge S. More than destructive: neutrophil-derived serine proteases in cytokine bioactivity control. J Leukoc Biol. 2001;69(2):197–206.
PubMed
CAS
Google Scholar
Louthrenoo W, Weerayutwattana N, Lertprasertsuke N, Sukitawut W. Serum muscle enzymes, muscle pathology and clinical muscle weakness: correlation in Thai patients with polymyositis/dermatomyositis. J Med Assoc Thailand. 2002;85(1):26–32.
Google Scholar
Zhang L, Wu G, Gao D, Liu G, Pan L, Ni L, Li Z, Wang Q. Factors associated with interstitial lung disease in patients with polymyositis and dermatomyositis: a systematic review and meta-analysis. PLoS One. 2016;11(5):e0155381.
Article
PubMed
PubMed Central
CAS
Google Scholar
Go DJ, Lee EY, Lee EB, Song YW, Konig MF, Park JK. Elevated erythrocyte sedimentation rate is predictive of interstitial lung disease and mortality in Dermatomyositis: a Korean retrospective cohort study. J Korean Med Sci. 2016;31(3):389–96.
Article
PubMed
PubMed Central
CAS
Google Scholar
Park JK, Gelber AC, George M, Danoff SK, Qubti MA, Christopher-Stine L. Pulmonary impairment, not muscle injury, is associated with elevated ESR in the idiopathic inflammatory myopathies. Rheumatol. 2013;52(7):1336–8.
Article
Google Scholar
Cen X, Zuo C, Yang M, Yin G, Xie Q. A clinical analysis of risk factors for interstitial lung disease in patients with idiopathic inflammatory myopathy. Clin Dev Immunol. 2013;2013:648570.
Article
PubMed
PubMed Central
Google Scholar
Wu C, Wang Q, He L, Yang E, Zeng X. Hospitalization mortality and associated risk factors in patients with polymyositis and dermatomyositis: a retrospective case-control study. PLoS One. 2018;13(2):e0192491.
Article
PubMed
PubMed Central
Google Scholar
Yang W, Wang X, Zhang W, Ying H, Xu Y, Zhang J, Min Q, Chen J. Neutrophil-lymphocyte ratio and platelet-lymphocyte ratio are 2 new inflammatory markers associated with pulmonary involvement and disease activity in patients with dermatomyositis. Clinica Chim Acta. 2017;465:11–6.
Article
CAS
Google Scholar
Boehme MW, Galle P, Stremmel W. Kinetics of thrombomodulin release and endothelial cell injury by neutrophil-derived proteases and oxygen radicals. Immunol. 2002;107(3):340–9.
Article
CAS
Google Scholar
Carden D, Xiao F, Moak C, Willis BH, Robinson-Jackson S, Alexander S. Neutrophil elastase promotes lung microvascular injury and proteolysis of endothelial cadherins. Am J Phys. 1998;275(2 Pt 2):H385–92.
CAS
Google Scholar
Ionescu CV, Cepinskas G, Savickiene J, Sandig M, Kvietys PR. Neutrophils induce sequential focal changes in endothelial adherens junction components: role of elastase. Microcirculation. 2003;10(2):205–20.
Article
PubMed
CAS
Google Scholar
Chua F, Laurent GJ. Neutrophil elastase: mediator of extracellular matrix destruction and accumulation. Proc Am Thorac Soc. 2006;3(5):424–7.
Article
PubMed
CAS
Google Scholar
Ferry G, Lonchampt M, Pennel L, de Nanteuil G, Canet E, Tucker GC. Activation of MMP-9 by neutrophil elastase in an in vivo model of acute lung injury. FEBS Lett. 1997;402(2–3):111–5.
Article
PubMed
CAS
Google Scholar
Wang S, Dangerfield JP, Young RE, Nourshargh S. PECAM-1, alpha6 integrins and neutrophil elastase cooperate in mediating neutrophil transmigration. J Cell Sci. 2005;118(Pt 9):2067–76.
Article
PubMed
CAS
Google Scholar
Berger SP, Seelen MA, Hiemstra PS, Gerritsma JS, Heemskerk E, van der Woude FJ, Daha MR. Proteinase 3, the major autoantigen of Wegener's granulomatosis, enhances IL-8 production by endothelial cells in vitro. J Am Soc Nephrol. 1996;7(5):694–701.
PubMed
CAS
Google Scholar
Shamamian P, Schwartz JD, Pocock BJ, Monea S, Whiting D, Marcus SG, Mignatti P. Activation of progelatinase a (MMP-2) by neutrophil elastase, cathepsin G, and proteinase-3: a role for inflammatory cells in tumor invasion and angiogenesis. J Cell Physiol. 2001;189(2):197–206.
Article
PubMed
CAS
Google Scholar
Kuckleburg CJ, Tilkens SB, Santoso S, Newman PJ. Proteinase 3 contributes to transendothelial migration of NB1-positive neutrophils. J Immunol. 2012;188(5):2419–26.
Article
PubMed
PubMed Central
CAS
Google Scholar
Hartsock A, Nelson WJ. Adherens and tight junctions: structure, function and connections to the actin cytoskeleton. Biochim Biophys Acta. 2008;1778(3):660–9.
Article
PubMed
CAS
Google Scholar
Corada M, Mariotti M, Thurston G, Smith K, Kunkel R, Brockhaus M, Lampugnani MG, Martin-Padura I, Stoppacciaro A, Ruco L, et al. Vascular endothelial-cadherin is an important determinant of microvascular integrity in vivo. Proc Natl Acad Sci U S A. 1999;96(17):9815–20.
Article
PubMed
PubMed Central
CAS
Google Scholar
Dejana E, Orsenigo F, Lampugnani MG. The role of adherens junctions and VE-cadherin in the control of vascular permeability. J Cell Sci. 2008;121(Pt 13):2115–22.
Article
PubMed
CAS
Google Scholar