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Table 2 Mean serum E2 levels by patient characteristics. For categorical variables, E2 levels are reported as mean (SD) by group. For continuous variables, we report the Pearson correlation

From: Estradiol levels are elevated in older men with diffuse cutaneous SSc and are associated with decreased survival

Characteristic

Group

n

E2 (SD)

p

Age at measurement

Years

83

− 0.086

0.439

Disease duration

Years

83

− 0.116

0.297

Baseline skin score

 

83

0.054

0.573

POL3

No

40

35.7 (19.9)

0.027

Yes

43

25.9 (13.2)

 

Scl-70

No

69

29.3 (16.9)

0.103

Yes

14

37.1 (18.9)

 

Other autoantibody

No

75

31.4 (17.8)

0.207

Yes

8

23.1 (11.9)

 

Organ involvement

 Lung

No

38

32.0 (20.6)

0.488

Yes

45

29.4 (14.3)

 

 Heart

No

76

29.4 (16.7)

0.037

Yes

7

43.7 (20.4)

 

 Kidney

No

65

31.0 (17.7)

0.704

Yes

18

29.2 (16.8)

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