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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Expression of interferon-regulated genes in juvenile dermatomyositis versus Mendelian autoinflammatory interferonopathies

Fig. 1

Peripheral blood interferon-regulated gene (IRG) scores in juvenile dermatomyositis (JDM) compared to monogenic autoinflammatory disease patients and healthy controls. Median and interquartile ranges are shown. Dotted horizontal line represents 95th percentile of healthy controls [22]. CANDLE (n = 11), SAVI (n = 7), NOMID (n = 18), HC (n = 26). JDM overall (n = 57):*q < 0.05, **q < 0.01. JDM-HQ (n = 14): **p < 0.01. JDM overall and JDM-HQ are higher than NOMID and HC; JDM overall is lower than CANDLE and SAVI. Abbreviations: IRG, interferon-regulated gene; JDM, juvenile dermatomyositis; JDM-HQ, highest-quartile scores in JDM; CANDLE, Chronic Atypical Neutrophilic Dermatosis with Lipodystrophy and Elevated temperature; SAVI, STING-Associated Vasculopathy with onset during Infancy; NOMID, neonatal-onset multisystem inflammatory disease; HC, healthy controls; IQR, interquartile range

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Arthritis Research & Therapy

ISSN: 1478-6362

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