Longitudinal immune cell monitoring identified CD14++ CD16+ intermediate monocyte as a marker of relapse in patients with ANCA-associated vasculitis

Table 5 Summary of 9 AAV patients with relapse

Case no.	Age (years)/sex	Induction Tx	At onset		At remission	At relapse
Case no.	Age (years)/sex	Induction Tx	ANCA/disease	Organ involvement	ANCA status	Organ involvement	ANCA status
Case 1	38/M	PSL+IVCY	PR3⁺ GPA	CNS, ENT	Negative	CNS, ENT	Positive
Case 2	57/F		PR3⁺ GPA	CNS, ENT	Negative	CNS, ENT	Positive
Case 3	74/M		MPO⁺ MPA	ILD, kidney	Negative	ILD, kidney	Negative
Case 4	76/F	PSL+RTX	MPO⁺ MPA	ILD, kidney, PNS	Negative	ILD, kidney, PNS	Negative
Case 5	78/F		MPO⁺ GPA	ENT, ILD, PNS	Negative	ILD, PNS	Negative
Case 6	75/F		MPO⁺ MPA	PNS	Negative	PNS	Negative
Case 7	90/M	PSL+AZA	MPO⁺ MPA	ILD, kidney	Negative	Kidney	Negative
Case 8	82/F	PSL monotherapy	PR3⁺ GPA	ENT, ILD	Negative	ILD	Negative
Case 9	72/F	PSL monotherapy	MPO⁺ GPA	CNS, ENT	Negative	CNS, ENT	Positive

PSL prednisolone, IVCY intravenous cyclophosphamide, RTX rituximab, AZA azathioprine, MPA microscopic polyangiitis, GPA granulomatosis with polyangiitis, ENT ear, nose, throat, PNS peripheral nervous system, ILD interstitial lung disease

ISSN: 1478-6362