Table 2 Characteristics of patients with Behçet’s syndrome after clustering on clinical manifestations
Characteristics | C1 (n = 307) | C2 (n = 124) | C3 (n = 156) | C4 (n = 142) | C5 (n = 131) |
|---|---|---|---|---|---|
Demographics | |||||
Age (IQR), years | 36 (27–47) | 39 (29–48) | 37 (28–48) | 33 (27–42) | 37 (29–44) |
Age at onset (IQR), years | 28 (20–38) | 28 (19–37) | 28 (19–38) | 25 (20–32) | 27 (21–35) |
Disease duration (IQR), years | 6 (3–10) | 9 (4–10) | 6 (3–10) | 7 (4–10) | 6 (3–10) |
Krause score | 3 (2–3) | 4 (3.3–5) | 4 (4–5) | 6 (5–6) | 6 (5–7) |
Sex ratio (M/F) | 0.64:1 | 0.97:1 | 1.08:1 | 2.94:1 | 2.54:1 |
Classification criteria | |||||
JPN (%) | 52.4 | 41.9 | 22.4 | 83.8 | 43.5 |
CHN (%) | 100 | 99.2 | 94.2 | 99.3 | 91.6 |
ICBD (%) | 100 | 79.0 | 62.8 | 99.3 | 87.8 |
ISG (%) | 52.8 | 45.2 | 23.1 | 81.7 | 43.5 |
Clinical manifestation | |||||
Oral ulceration (%) | 100 | 100 | 98.0 | 99.2 | 100 |
Genital ulceration (%) | 100 | 75.8 | 61.5 | 58.5 | 63.4 |
Erythema nodosum (%) | 40.7 | 44.4 | 19.2 | 48.6 | 49.6 |
Folliculitis (%) | 20.8 | 28.2 | 25.6 | 28.2 | 22.1 |
Arthritis/arthralgia (%) | 0 | 100 | 1.3 | 16.9 | 23.7 |
Major organ involvement | |||||
Uveitis (%) | 0 | 0 | 0 | 100 | 9.9 |
Intestinal involvement (%) | 0 | 14.5 | 92.3 | 5.6 | 6.1 |
Esophageal lesions (%) | 0 | 1.6 | 20.5 | 0.7 | 0.8 |
Vascular involvement (%) | 0 | 0 | 0 | 0 | 44.3 |
Cardiac lesion (%) | 0 | 0 | 0 | 0 | 33.6 |
Myelodysplastic syndrome (%) | 0.3 | 1.6 | 1.9 | 0 | 0 |
Central nervous system involvement (%) | 0 | 0.8 | 1.9 | 0.7 | 19.8 |