Fig. 1
![Fig. 1](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs13075-021-02475-1/MediaObjects/13075_2021_2475_Fig1_HTML.png)
Expression of regulatory T cell (Treg) levels in C57BL/6.NOD-Aec1Aec (SjS) mice compared to C57BL/6 (B6) females. CD4+ T cell analysis was performed on two groups (n = 5 mice/group) of age-matched B6 and SjS females (32 weeks of age) and evaluated for the expression of IL-10, CD25, and Foxp3. Isolated lymphocytes from (a–j) head and neck lymph nodes (HNLNs) and (k–t) spleens were stained for expression of (a, b, g–l, q–t) IL-10, (c–f, i, j, m–p, s, t) CD25, and (e–j, o–t) Foxp3; **P < 0.01, ***P < 0.001, ****P < 0.0001 denote significant differences between SjS and B6 mice