Table 2 The LRT, Cochran’s Q test, and \({\theta }^{2}\) in MR analysis with coarsened exposures for gout on hypertension under different scenarios
Remove SNPs?a | Measured confounders? | LRT (p-value) | Cochran's Q test (p-value) | \({\uptheta }^{2}\) |
|---|---|---|---|---|
No | Yes | 892.4092 (< 2.22 × 10−16) | 5.2169 (0.1566) | 0.047 |
No | No | 832.1562 (< 2.22 × 10−16) | 3.4188 (0.3314) | 0.047 |
Yes | Yes | 862.6535 (< 2.22 × 10−16) | 5.2209 (0.1563) | 0.045 |
Yes | No | 804.67 (< 2.22 × 10−16) | 3.4271 (0.3303) | 0.045 |