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Table 4 Relation between clinical and radiographic parameters and VAS pain: generalized estimating equations

From: Radiographic damage in early rheumatoid arthritis is associated with increased disability but not with pain—a 5-year follow-up study

Variable

Crude

Adj. for sex and age

Multivariate model

β (95% CI)

β (95% CI)

β (95% CI)

Female sex

2.96 (−2.01, 7.93)

3.63 (−1.11, 8.37)

Age (per year)

−0.19 (−0.36, −0.01)

−0.26 (−0.43, −0.09)

Symptom duration (months)

−0.46 (−1.28, 0.37)

−0.56 (−1.39, 0.28)

RF seropositivity

1.70 (−3.21, 6.61)

1.44 (−3.49, 6.37)

Anti-CCP seropositivity

−1.28 (−4.06, 6.62)

1.43 (−3.81, 6.67)

SJC28

1.90 (1.53, 2.27)

1.92 (1.55, 2.30)

1.59 (1.21, 1.96)

TJC28

1.79 (1.49, 2.10)

1.78 (1.47, 2.08)

ESR (per mm/h)

0.41 (0.32, 0.51)

0.43 (0.34, 0.52)

0.34 (0.24, 0.43)

CRP (per mg/l)

0.36 (0.27, 0.44)

0.37 (0.29, 0.45)

SHS

−0.04 (−0.18, 0.10)

−0.02 (−0.15, 0.12)

ES

−0.10 (−0.22, 0.43)

0.12 (−0.19, 0.43)

JSNS

−0.12 (−0.30, 0.05)

−0.09 (−0.27, 0.09)

  1. Bold text indicates statistical significance with p-values <0.05. Italic text indicates p-values ≥0.05 and <0.10. Bold plus italic text indicates p-values <0.001. VAS visual analogue scale, CI confidence interval, RF rheumatoid factor, Anti-CCP anti-cyclic citrullinated peptide, SJC28 swollen joint count in 28 joints, TJC28 tender joint count in 28 joints, CRP C-reactive protein, ESR erythrocyte sedimentation rate, SHS Sharp-van der Heijde score, ES erosion score, JSNS joint space narrowing score