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Table 3 Characteristics of the participants among participants who maintained sufficient vitamin D levels and participants who did not maintain sufficient vitamin D levels at 60-month follow-up

From: Long-term effects of vitamin D supplementation and maintaining sufficient vitamin D on knee osteoarthritis over 5 years

 

Vitamin D non-maintainer (n = 61)

Vitamin D maintainer (n = 79)

Age, years

68.3 (6.5)

68.2 (6.6)

Female, n (%)

29 (48%)

35 (44%)

BMI, kg/m2

29.6 (6.7)

27.8 (13.4)

Serum 25(OH)D levels, nmol/l

51.1 (18.8)

69.4 (14.4)

Serum hs-CRP, mg/ml

1.9 (1.6)

2.0 (2.7)

Serum IL6, pg/mL

1.5 (3.3)

1.3 (1.2)

Knee surgerya, n (%)

11 (18%)

11 (14%)

 Total knee replacement, n (%)

10 (16%)

8 (10%)

Vitamin D supplementation from 2014 to 2016

 No regular use, n (%)

44 (72%)

48 (61%)

 Regular use for 1 or 2 years, n (%)

8 (13%)

14 (18%)

 Regular use for 3 years, n (%)

9 (15%)

17 (22%)

WOMAC

 Pain (0–500)

106.0 (96.5)

84.0 (79.2)

 Function (0–1700)

353.6 (322.1)

300.1 (293.6)

 Stiffness (0–200)

45.8 (43.6)

37.9 (36.7)

Study knee VAS pain (0–100)

33.4 (27.2)

30.4 (26.6)

AQoL utility (0–1)

0.7 (0.2)

0.7 (0.2)

PHQ-9 (0–27)

3.1 (3.1)

2.9 (3.0)

 No depression, n (%)

46 (75%)

58 (73%)

 Mild depression, n (%)

12 (20%)

17 (22%)

 Moderate to severe depression, n (%)

3 (5%)

4 (5%)

MET-min/week

3383.1 (3662.7)

3810.3 (3741.4)

Physical activity categories

  

 Low

20 (32.8%)

14 (17.7%)

 Moderate

17 (27.9%)

25 (31.6%)

 High

24 (39.3%)

40 (50.6%)

  1. Data were shown as mean (SD) or otherwise states
  2. BMI body mass index, hs-CRP high sensitivity C Reactive protein, TKR total knee replacement, WOMAC Western Ontario and McMaster Universities Osteoarthritis Index, AQoL Assessment of Quality of Life, PHQ9 Patient Health Questionnaire-9, MET metabolic equivalent of task
  3. aIncluding TKR, partial knee replacement, bone graft, and partial meniscus removal, kneecap alignment, replacement of quadriceps tendon, and arthroscopy