Table 4 Change in clinical symptoms and serum inflammatory markers over 60 months in participants who maintained sufficient vitamin D levels and participants who did not maintain sufficient vitamin D levels
Vitamin D non-maintainer | Vitamin D maintainer | Between-group change | |||
|---|---|---|---|---|---|
n | change | n | change | ||
WOMAC pain | 60 | − 15.3 (− 37.6, 7.1) | 79 | − 38.4 (− 57.9, − 18.9) | − 23.1 (− 52.9, 6.6) |
No surgery | 49 | − 10.5 (− 34.7, 13.6) | 68 | − 44.4 (− 65, − 23.8) | − 33.9 (− 65.7, − 2) |
WOMAC function | 60 | − 42.2 (− 107.8, 23.4) | 79 | − 113 (− 170.3, − 55.7) | − 70.8 (− 158.1, 16.5) |
No surgery | 49 | − 22.4 (− 92.7, 48) | 68 | − 127.9 (− 187.8, − 68) | − 105.5 (− 198.2, − 12.8) |
WOMAC stiffness | 60 | − 12.2 (− 22, − 2.5) | 79 | − 15.4 (− 23.9, − 6.9) | − 3.1 (− 16.1, 9.8) |
No surgery | 49 | − 9.3 (− 19.7, 1.2) | 68 | − 16 (− 24.8, − 7.2) | − 6.7 (− 20.4, 7) |
Study knee VAS pain | 61 | − 13.1 (− 19.4, − 6.8) | 79 | − 17.4 (− 22.9, − 11.8) | − 4.2 (− 12.7, 4.2) |
No surgery | 50 | − 12 (− 19, − 5.1) | 68 | − 18.3 (− 24.3, − 12.3) | − 6.3 (− 15.5, 2.9) |
Utility | 60 | − 0.023 (− 0.057, 0.01) | 78 | − 0.013 (− 0.042, 0.016) | 0.01 (− 0.034, 0.054) |
No surgery | 49 | − 0.031 (− 0.068, 0.005) | 67 | − 0.01 (− 0.041, 0.021) | 0.021 (− 0.027, 0.07) |
PHQ9 | 61 | 0.2 (− 0.6, 0.9) | 79 | − 0.6 (− 1.3, 0.1) | − 0.8 (− 1.8, 0.3) |
No surgery | 50 | 0.5 (− 0.3, 1.4) | 68 | − 0.5 (− 1.2, 0.3) | − 1 (− 2.1, 0.1) |
IL6 | 57 | − 5 (− 9.9, − 0.1) | 73 | − 5.1 (− 9.4, − 0.8) | − 0.1 (− 6.6, 6.5) |
No surgery | 47 | − 5.5 (− 11.4, 0.5) | 62 | − 5.5 (− 10.6, − 0.4) | − 0.1 (− 7.9, 7.8) |
hs-CRP | 57 | − 0.4 (− 0.9, 0.2) | 73 | 0.1 (− 0.4, 0.5) | 0.4 (− 0.3, 1.1) |
No surgery | 47 | − 0.3 (− 0.8, 0.3) | 62 | − 0.1 (− 0.6, 0.4) | 0.2 (− 0.6, 0.9) |