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Table 1 Selected functional polymorphisms in the IL6R gene

From: Impact of IL6R genetic variants on treatment efficacy and toxicity response to sarilumab in rheumatoid arthritis

refSeg

Genomic position (GRCh38)

MAF

Alleles

rs12083537

chr1:154408627

0.21

A > G

rs11265618

chr1:154457616

0.17

C > T

rs4329505

chr1:154459944

0.17

T > C

rs2228145

chr1:154454494

0.40

A > C

rs4537545

chr1:154446403

0.41

C > T

rs4845625

chr1:154449591

0.43

T > C

  1. The minor allele is highlighted in bold
  2. Abbreviations: IL6R Interleukin 6 Receptor, MAF Minor allele frequency reported in the European population
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Arthritis Research & Therapy

ISSN: 1478-6362

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