Table 5 Associations between the SNPs and hepatotoxicity and dyslipidemia
SNPs | Genotype (n) | Hepatotoxicity | Dyslipidemia | ||||
|---|---|---|---|---|---|---|---|
% | Genetic model | p | % | Genetic model | p | ||
rs4845625 | T/T (9) | 33.3 | Cod | 0.07 | 44.4 | Cod | 0.14 |
C/T (28) | 7.1 | Dom | 0.027 | 35.7 | Rec | 0.056 | |
C/C (25) | 4 | 16 | |||||
rs11265618 | T/T (42) | 14.3 | Cod | 0.08 | 23.8 | Cod | 0.41 |
C/T (17) | 0 | Dom | 0.026 | 41.2 | Dom | 0.19 | |
C/C (3) | 0 | 33.3 | |||||
rs4329505 | T/T (42) | 14.3 | Cod | 0.08 | 23.8 | Cod | 0.41 |
C/T (17) | 0 | Dom | 0.026 | 41.2 | Dom | 0.19 | |
C/C (3) | 0 | 33.3 | |||||
rs2228145 | A/A (22) | 13.6 | Cod | 0.75 | 50 | Cod | 0.028 |
C/A (27) | 7.4 | Dom | 0.44 | 5 | Dom | 0.008 | |
C/C (13) | 7.7 | 2 | |||||
rs4537545 | C/C (20) | 15 | Cod | 0.64 | 50 | Cod | 0.046 |
C/T (28) | 7.1 | Dom | 0.34 | 17.9 | Dom | 0.014 | |
T/T (14) | 7.1 | 21.4 | |||||