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Volume 8 Supplement 1

Gout and Hyperuricemia


Edited by Robert Terkeltaub and Bruce Cronstein

Supported by an educational grant from TAP Pharmaceuticals Inc.

  1. First identified by the Egyptians in 2640 BC, podagra (acute gout occurring in the first metatarsophalangeal joint) was later recognized by Hippocrates in the fifth century BC, who referred to it as 'the unwal...

    Authors: George Nuki and Peter A Simkin
    Citation: Arthritis Research & Therapy 2006 8(Suppl 1):S1
  2. Gouty arthritis is a characteristically intense acute inflammatory reaction that erupts in response to articular deposits of monosodium urate (MSU) crystals. Important recent molecular biologic advances in thi...

    Authors: Bruce N Cronstein and Robert Terkeltaub
    Citation: Arthritis Research & Therapy 2006 8(Suppl 1):S3
  3. Although dietary, genetic, or disease-related excesses in urate production may contribute to hyperuricemia, impaired renal excretion of uric acid is the dominant cause of hyperuricemia in the majority of patie...

    Authors: Robert Terkeltaub, David A Bushinsky and Michael A Becker
    Citation: Arthritis Research & Therapy 2006 8(Suppl 1):S4

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