van Holten J, Plater-Zyberk C, Tak PP: Interferon-beta for treatment of rheumatoid arthritis?. Arthritis Res. 2002, 4: 346-352. 10.1186/ar598.
Article
PubMed Central
PubMed
Google Scholar
Stark GR, Kerr IM, Williams BR, Silverman RH, Schreiber RD: How cells respond to interferons. Annu Rev Biochem. 1998, 67: 227-264. 10.1146/annurev.biochem.67.1.227.
Article
CAS
PubMed
Google Scholar
De ME, De Maeyer-Guignard J: Type I interferons. Int Rev Immunol. 1998, 17: 53-73.
Article
Google Scholar
Tak PP, Hart BA, Kraan MC, Jonker M, Smeets TJ, Breedveld FC: The effects of interferon beta treatment on arthritis. Rheumatology (Oxford). 1999, 38: 362-369. 10.1093/rheumatology/38.4.362.
Article
CAS
Google Scholar
Rep MH, Hintzen RQ, Polman CH, van Lier RA: Recombinant interferon-beta blocks proliferation but enhances interleukin-10 secretion by activated human T-cells. J Neuroimmunol. 1996, 67: 111-118. 10.1016/0165-5728(96)00060-4.
Article
CAS
PubMed
Google Scholar
Rep MH, Schrijver HM, van Lopik T, Hintzen RQ, Roos MT, Ader HJ, Polman CH, van Lier RA: Interferon (IFN)-beta treatment enhances CD95 and interleukin 10 expression but reduces interferon-gamma producing T cells in MS patients. J Neuroimmunol. 1999, 96: 92-100. 10.1016/S0165-5728(98)00271-9.
Article
CAS
PubMed
Google Scholar
Palmer G, Mezin F, Juge-Aubry CE, Plater-Zyberk C, Gabay C, Guerne PA: Interferon beta stimulates interleukin 1 receptor antagonist production in human articular chondrocytes and synovial fibroblasts. Ann Rheum Dis. 2004, 63: 43-49. 10.1136/ard.2002.005546.
Article
PubMed Central
CAS
PubMed
Google Scholar
Jungo F, Dayer JM, Modoux C, Hyka N, Burger D: IFN-beta inhibits the ability of T lymphocytes to induce TNF-alpha and IL-1beta production in monocytes upon direct cell-cell contact. Cytokine. 2001, 14: 272-282. 10.1006/cyto.2001.0884.
Article
CAS
PubMed
Google Scholar
Yong VW, Chabot S, Stuve O, Williams G: Interferon beta in the treatment of multiple sclerosis: mechanisms of action. Neurology. 1998, 51: 682-689.
Article
CAS
PubMed
Google Scholar
Ossege LM, Sindern E, Patzold T, Malin JP: Immunomodulatory effects of interferon-beta-1b in patients with multiple sclerosis. Int Immunopharmacol. 2001, 1: 1085-1100. 10.1016/S1567-5769(01)00039-X.
Article
CAS
PubMed
Google Scholar
Triantaphyllopoulos KA, Williams RO, Tailor H, Chernajovsky Y: Amelioration of collagen-induced arthritis and suppression of interferon-gamma, interleukin-12, and tumor necrosis factor alpha production by interferon-beta gene therapy. Arthritis Rheum. 1999, 42: 90-99. 10.1002/1529-0131(199901)42:1<90::AID-ANR12>3.0.CO;2-A.
Article
CAS
PubMed
Google Scholar
Sundel RP, Wallace CA, Zurakowski Boston D: Pilot trial of interferon beta-1a in JRA [abstract]. Arthritis Rheum. 2001, 44: s272-
Google Scholar
Smeets TJ, Dayer JM, Kraan MC, Versendaal J, Chicheportiche R, Breedveld FC, Tak PP: The effects of interferon-beta treatment of synovial inflammation and expression of metalloproteinases in patients with rheumatoid arthritis. Arthritis Rheum. 2000, 43: 270-274. 10.1002/1529-0131(200002)43:2<270::AID-ANR5>3.0.CO;2-H.
Article
CAS
PubMed
Google Scholar
Takayanagi H, Kim S, Matsuo K, Suzuki H, Suzuki T, Sato K, Yokochi T, Oda H, Nakamura K, Ida N, Wagner EF, Taniguchi T: RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-beta. Nature. 2002, 416: 744-749. 10.1038/416744a.
Article
CAS
PubMed
Google Scholar
Alliston T, Derynck R: Medicine: interfering with bone remodelling. Nature. 2002, 416: 686-687. 10.1038/416686a.
Article
CAS
PubMed
Google Scholar
Tak PP, Firestein GS: NF-kappaB: a key role in inflammatory diseases. J Clin Invest. 2001, 107: 7-11.
Article
PubMed Central
CAS
PubMed
Google Scholar
Gerlag DM, Ransone L, Tak PP, Han Z, Palanki M, Barbosa MS, Boyle D, Manning AM, Firestein GS: The effect of a T cell-specific NF-kappa B inhibitor on in vitro cytokine production and collagen-induced arthritis. J Immunol. 2000, 165: 1652-1658.
Article
CAS
PubMed
Google Scholar
Plater-Zyberk C, Buckton J, Thompson S, Spaull J, Zanders E, Papworth J, Life PF: Amelioration of arthritis in two murine models using antibodies to oncostatin M. Arthritis Rheum. 2001, 44: 2697-2702. 10.1002/1529-0131(200111)44:11<2697::AID-ART450>3.0.CO;2-#.
Article
CAS
PubMed
Google Scholar
Williams RO, Feldmann M, Maini RN: Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. Proc Natl Acad Sci USA. 1992, 89: 9784-9788.
Article
PubMed Central
CAS
PubMed
Google Scholar
Dudler J, Renggli-Zulliger N, Busso N, Lotz M, So A: Effect of interleukin 17 on proteoglycan degradation in murine knee joints. Ann Rheum Dis. 2000, 59: 529-532. 10.1136/ard.59.7.529.
Article
PubMed Central
CAS
PubMed
Google Scholar
Tak PP, Smeets TJ, Daha MR, Kluin PM, Meijers KA, Brand R, Meiders AE, Breedveld FC: Analysis of the synovial cell infiltrate in early rheumatoid synovial tissue in relation to local disease activity. Arthritis Rheum. 1997, 40: 217-225.
Article
CAS
PubMed
Google Scholar
Thurkow EW, van der Heijden IM, Breedveld FC, Smeets TJ, Daha MR, Kluin PM, Meinders AE, Tak PP: Increased expression of IL-15 in the synovium of patients with rheumatoid arthritis compared with patients with Yersinia-induced arthritis and osteoarthritis. J Pathol. 1997, 181: 444-450. 10.1002/(SICI)1096-9896(199704)181:4<444::AID-PATH778>3.3.CO;2-F.
Article
CAS
PubMed
Google Scholar
Dayer JM, Beutler B, Cerami A: Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts. J Exp Med. 1985, 162: 2163-2168. 10.1084/jem.162.6.2163.
Article
CAS
PubMed
Google Scholar
Firestein GS: Cytokine networks in rheumatoid arthritis: implications for therapy. Agents Actions Suppl. 1995, 47: 37-51.
CAS
PubMed
Google Scholar
Moore KW, O'Garra A, de Waal MR, Vieira P, Mosmann TR: Interleukin-10. Annu Rev Immunol. 1993, 11: 165-190. 10.1146/annurev.iy.11.040193.001121.
Article
CAS
PubMed
Google Scholar
Wei XQ, Leung BP, Arthur HM, McInnes IB, Liew FY: Reduced incidence and severity of collagen-induced arthritis in mice lacking IL-18. J Immunol. 2001, 166: 517-521.
Article
CAS
PubMed
Google Scholar
Buchwalder PA, Buclin T, Trinchard I, Munafo A, Biollaz J: Pharmacokinetics and pharmacodynamics of IFN-beta 1a in healthy volunteers. J Interferon Cytokine Res. 2000, 20: 857-866. 10.1089/10799900050163226.
Article
CAS
PubMed
Google Scholar
Miyazaki T, Katagiri H, Kanegae Y, Takayanagi H, Sawada Y, Yamamoto A, Pando MP, Asano T, Verma IM, Oda H, Nakamura K, Tanaka S: Reciprocal role of ERK and NF-kappaB pathways in survival and activation of osteoclasts. J Cell Biol. 2000, 148: 333-342. 10.1083/jcb.148.2.333.
Article
PubMed Central
CAS
PubMed
Google Scholar
Missbach M, Jeschke M, Feyen J, Muller K, Glatt M, Green J, Susa M: A novel inhibitor of the tyrosine kinase Src suppresses phosphorylation of its major cellular substrates and reduces bone resorption in vitro and in rodent models in vivo. Bone. 1999, 24: 437-449. 10.1016/S8756-3282(99)00020-4.
Article
CAS
PubMed
Google Scholar
Chiusaroli R, Sanjay A, Hendriksen K, Engsig MT, Horne WC, Gu H, Baron R: Deletion of the gene encoding c-Cbl alters the ability of osteoclasts to migrate, delaying resorption and ossification of cartilage during the development of long bones. Dev Biol. 2003, 261: 537-547. 10.1016/S0012-1606(03)00299-9.
Article
CAS
PubMed
Google Scholar
Berger LC, Hawley RG: Interferon-beta interrupts interleukin-6-dependent signaling events in myeloma cells. Blood. 1997, 89: 261-271.
CAS
PubMed
Google Scholar
Pilling D, Akbar AN, Girdlestone J, Orteu CH, Borthwick NJ, Amft N, Scheel-Toellner D, Buckley CD, Salmon M: Interferon-beta mediates stromal cell rescue of T cells from apoptosis. Eur J Immunol. 1999, 29: 1041-1050. 10.1002/(SICI)1521-4141(199903)29:03<1041::AID-IMMU1041>3.0.CO;2-#.
Article
CAS
PubMed
Google Scholar
Van Weyenbergh J, Wietzerbin J, Rouillard D, Barral-Netto M, Liblau R: Treatment of multiple sclerosis patients with interferon-beta primes monocyte-derived macrophages for apoptotic cell death. J Leukoc Biol. 2001, 70: 745-748.
CAS
PubMed
Google Scholar
Joosten LA, Helsen MM, van De Loo FA, van Den Berg WB: Anti-cytokine treatment of established type II collagen-induced arthritis in DBA/1 mice. A comparative study using anti-TNF alpha, anti-IL-1 alpha/beta, and IL-1Ra. Arthritis Rheum. 1996, 39: 797-809.
Article
CAS
PubMed
Google Scholar
Moreland LW, Schiff MH, Baumgartner SW, Tindall EA, Fleischmann RM, Bulpitt KJ, Weaver AL, Keystone EC, Furst DE, Meas PJ, Ruderman EM, Horwitz DA, Arkfeld DG, Garrison L, Burge DJ, Blosch CM, Lange ML, MacDonnell ND, Weinblatt ME: Etanercept therapy in rheumatoid arthritis. A randomized, controlled trial. Ann Intern Med. 1999, 130: 478-486.
Article
CAS
PubMed
Google Scholar
Weinblatt ME, Kremer JM, Bankhurst AD, Bulpitt KJ, Fleischmann RM, Fox RI, Jackson CG, Lange M, Burge DJ: A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate. N Engl J Med. 1999, 340: 253-259. 10.1056/NEJM199901283400401.
Article
CAS
PubMed
Google Scholar
Nishimoto N, Yoshizaki K, Maeda K, Kuritani T, Deguchi H, Sato B, Imai N, Suemura M, Kakehi T, Takagi N, Kishimoto T: Toxicity, pharmacokinetics, and dose-finding study of repetitive treatment with the humanized anti-interleukin 6 receptor antibody MRA in rheumatoid arthritis. Phase I/II clinical study. J Rheumatol. 2003, 30: 1426-1435.
CAS
PubMed
Google Scholar
van Roon JA, Lafeber FP, Bijlsma JW: Synergistic activity of interleukin-4 and interleukin-10 in suppression of inflammation and joint destruction in rheumatoid arthritis. Arthritis Rheum. 2001, 44: 3-12. 10.1002/1529-0131(200101)44:1<3::AID-ANR2>3.0.CO;2-U.
Article
CAS
PubMed
Google Scholar
Maini R, Paulus H, Breedveld F, Moreland LW, William St Clair E, Russel A: rHUIL-10 in subjects with active rheumatoid arthritis (RA): a phase I and cytokine response study [abstract]. Arthritis Rheum. 1997, 40: s224-
Google Scholar
Genovese M, Chakravaty E, Krishnan E, Moreland LW: A randomized, controlled trial of interferon-β-1a in patients with rheumatoid arthritis: a pilot study. Arthritis Res Ther. 2004, 6: R73-R77. 10.1186/ar1026.
Article
PubMed Central
CAS
PubMed
Google Scholar