Firestein GS: Evolving concepts of rheumatoid arthritis. Nature. 2003, 423: 356-361. 10.1038/nature01661.
Article
CAS
PubMed
Google Scholar
Maruotti N, Cantatore FP, Crivellato E, Vacca A, Ribatti D: Angiogenesis in rheumatoid arthritis. Histol Histopathol. 2006, 21: 557-566.
CAS
PubMed
Google Scholar
De Bandt M, Ben Mahdi MH, Ollivier V, Grossin M, Dupuis M, Gaudry M, Bohlen P, Lipson KE, Rice A, Wu Y, et al: Blockade of vascular endothelial growth factor receptor I (VEGF-RI), but not VEGF-RII, suppresses joint destruction in the K/B × N model of rheumatoid arthritis. J Immunol. 2003, 171: 4853-4859.
Article
CAS
PubMed
Google Scholar
Oliver G, Detmar M: The rediscovery of the lymphatic system: old and new insights into the development and biological function of the lymphatic vasculature. Genes Dev. 2002, 16: 773-783. 10.1101/gad.975002.
Article
CAS
PubMed
Google Scholar
Podgrabinska S, Braun P, Velasco P, Kloos B, Pepper MS, Skobe M: Molecular characterization of lymphatic endothelial cells. Proc Natl Acad Sci USA. 2002, 99: 16069-16074. 10.1073/pnas.242401399.
Article
PubMed Central
CAS
PubMed
Google Scholar
Kriehuber E, Breiteneder-Geleff S, Groeger M, Soleiman A, Schoppmann SF, Stingl G, Kerjaschki D, Maurer D: Isolation and characterization of dermal lymphatic and blood endothelial cells reveal stable and functionally specialized cell lineages. J Exp Med. 2001, 194: 797-808. 10.1084/jem.194.6.797.
Article
PubMed Central
CAS
PubMed
Google Scholar
Mäkinen T, Veikkola T, Mustjoki S, Karpanen T, Catimel B, Nice EC, Wise L, Mercer A, Kowalski H, Kerjaschki D, et al: Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3. EMBO J. 2001, 20: 4762-4773. 10.1093/emboj/20.17.4762.
Article
PubMed Central
PubMed
Google Scholar
Hirakawa S, Hong YK, Harvey N, Schacht V, Matsuda K, Libermann T, Detmar M: Identification of vascular lineage-specific genes by transcriptional profiling of isolated blood vascular and lymphatic endothelial cells. Am J Pathol. 2003, 162: 575-586.
Article
PubMed Central
CAS
PubMed
Google Scholar
Cao R, Eriksson A, Kubo H, Alitalo K, Cao Y, Thyberg J: Comparative evaluation of FGF-2-, VEGF-A-, and VEGF-C-induced angiogenesis, lymphangiogenesis, vascular fenestrations, and permeability. Circ Res. 2004, 94: 664-670. 10.1161/01.RES.0000118600.91698.BB.
Article
CAS
PubMed
Google Scholar
Brown P: Lymphatic system: unlocking the drains. Nature. 2005, 436: 456-458. 10.1038/436456a.
Article
CAS
PubMed
Google Scholar
Alitalo K, Tammela T, Petrova TV: Lymphangiogenesis in development and human disease. Nature. 2005, 438: 946-953. 10.1038/nature04480.
Article
CAS
PubMed
Google Scholar
Karkkainen MJ, Haiko P, Sainio K, Partanen J, Taipale J, Petrova TV, Jeltsch M, Jackson DG, Talikka M, Rauvala H, et al: Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Nat Immunol. 2004, 5: 74-80. 10.1038/ni1013.
Article
CAS
PubMed
Google Scholar
Lee J, Gray A, Yuan J, Luoh SM, Avraham H, Wood WI: Vascular endothelial growth factor-related protein: a ligand and specific activator of the tyrosine kinase receptor Flt4. Proc Natl Acad Sci USA. 1996, 93: 1988-1992. 10.1073/pnas.93.5.1988.
Article
PubMed Central
CAS
PubMed
Google Scholar
Kerjaschki D, Huttary N, Raab I, Regele H, Bojarski-Nagy K, Bartel G, Kröber SM, Greinix H, Rosenmaier A, Karlhofer F, et al: Lymphatic endothelial progenitor cells contribute to de novo lymphangiogenesis in human renal transplants. Nat Med. 2006, 12: 230-234. 10.1038/nm1340.
Article
CAS
PubMed
Google Scholar
Maruyama K, Ii M, Cursiefen C, Jackson DG, Keino H, Tomita M, Van Rooijen N, Takenaka H, D'Amore PA, Stein-Streilein J, et al: Inflammation-induced lymphangiogenesis in the cornea arises from CD11b-positive macrophages. J Clin Invest. 2005, 115: 2363-2372. 10.1172/JCI23874.
Article
PubMed Central
CAS
PubMed
Google Scholar
Hamrah P, Chen L, Zhang Q, Dana MR: Novel expression of vascular endothelial growth factor receptor (VEGFR)-3 and VEGF-C on corneal dendritic cells. Am J Pathol. 2003, 163: 57-68.
Article
PubMed Central
CAS
PubMed
Google Scholar
Baluk P, Tammela T, Ator E, Lyubynska N, Achen MG, Hicklin DJ, Jeltsch M, Petrova TV, Pytowski B, Stacker SA, et al: Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation. J Clin Invest. 2005, 115: 247-257. 10.1172/JCI200522037.
Article
PubMed Central
CAS
PubMed
Google Scholar
Chilov D, Kukk E, Taira S, Jeltsch M, Kaukonen J, Palotie A, Joukov V, Alitalo K: Genomic organization of human and mouse genes for vascular endothelial growth factor C. J Biol Chem. 1997, 272: 25176-25183. 10.1074/jbc.272.40.25176.
Article
CAS
PubMed
Google Scholar
Ristimäki A, Narko K, Enholm B, Joukov V, Alitalo K: Proinflammatory cytokines regulate expression of the lymphatic endothelial mitogen vascular endothelial growth factor-C. J Biol Chem. 1998, 273: 8413-8418. 10.1074/jbc.273.14.8413.
Article
PubMed
Google Scholar
Li P, Schwarz EM, O'Keefe RJ, Ma L, Looney RJ, Ritchlin CT, Boyce BF, Xing L: Systemic tumor necrosis factor alpha mediates an increase in peripheral CD11bhigh osteoclast precursors in tumor necrosis factor alpha-transgenic mice. Arthritis Rheum. 2004, 50: 265-276. 10.1002/art.11419.
Article
CAS
PubMed
Google Scholar
Kim N, Kadono Y, Takami M, Lee J, Lee SH, Okada F, Kim JH, Kobayashi T, Odgren PR, Nakano H, et al: Osteoclast differentiation independent of the TRANCE-RANK-TRAF6 axis. J Exp Med. 2005, 202: 589-595. 10.1084/jem.20050978.
Article
PubMed Central
CAS
PubMed
Google Scholar
Xing L, Schwarz EM, Boyce BF: Osteoclast precursors, RANKL/RANK, and immunology. Immunol Rev. 2005, 208: 19-29. 10.1111/j.0105-2896.2005.00336.x.
Article
CAS
PubMed
Google Scholar
Kouskoff V, Korganow AS, Duchatelle V, Degott C, Benoist C, Mathis D: Organ-specific disease provoked by systemic autoimmunity. Cell. 1996, 87: 811-822. 10.1016/S0092-8674(00)81989-3.
Article
CAS
PubMed
Google Scholar
Takeshita S, Kaji K, Kudo A: Identification and characterization of the new osteoclast progenitor with macrophage phenotypes being able to differentiate into mature osteoclasts. J Bone Miner Res. 2000, 15: 1477-1488. 10.1359/jbmr.2000.15.8.1477.
Article
CAS
PubMed
Google Scholar
Zhang Q, Badell IR, Schwarz EM, Boulukos KE, Yao Z, Boyce BF, Xing L: Tumor necrosis factor prevents alendronate-induced osteoclast apoptosis in vivo by stimulating Bcl-xL expression through Ets-2. Arthritis Rheum. 2005, 52: 2708-2718. 10.1002/art.21236.
Article
CAS
PubMed
Google Scholar
Brühl H, Cihak J, Schneider MA, Plachý J, Rupp T, Wenzel I, Shakarami M, Milz S, Ellwart JW, Stangassinger M, et al: Dual role of CCR2 during initiation and progression of collagen-induced arthritis: evidence for regulatory activity of CCR2+ T cells. J Immunol. 2004, 172: 890-898.
Article
PubMed
Google Scholar
Kamata K, Kamijo S, Nakajima A, Koyanagi A, Kurosawa H, Yagita H, Okumura K: Involvement of TNF-like weak inducer of apoptosis in the pathogenesis of collagen-induced arthritis. J Immunol. 2006, 177: 6433-6439.
Article
CAS
PubMed
Google Scholar
Yao Z, Li P, Zhang Q, Schwarz EM, Keng P, Arbini A, Boyce BF, Xing L: Tumor necrosis factor-{alpha} increases circulating osteoclast precursor numbers by promoting their proliferation and differentiation in the bone marrow through up-regulation of c-Fms expression. J Biol Chem. 2006, 281: 11846-11855. 10.1074/jbc.M512624200.
Article
CAS
PubMed
Google Scholar
Boyce BF: Bone biopsy and histomorphometry in metabolic bone disease. New Techniques in Metabolic Bone Disease. Edited by: Stevenson JC. 1990, London: Butterworths, 110-131.
Chapter
Google Scholar
Feng JQ, Xing L, Zhang JH, Zhao M, Horn D, Chan J, Boyce BF, Harris SE, Mundy GR, Chen D: NF-kappaB specifically activates BMP-2 gene expression in growth plate chondrocytes in vivo and in a chondrocyte cell line in vitro. J Biol Chem. 2003, 278: 29130-29135. 10.1074/jbc.M212296200.
Article
CAS
PubMed
Google Scholar
Proulx TS, Kwok E, Beck CA, Shealy D, Ritchlin CT, Awad HA, Boyce BF, Xing L, Schwarz EM: Longitudinal assessment of synovial, lymph node, and bone volumes in inflammatory arthritis in mice using in vivoMRI and micro-CT. Arthritis Rheum.
Ritchlin CT, Haas-Smith SA, Li P, Hicks DG, Schwarz EM: Mechanisms of TNF-alpha- and RANKL-mediated osteoclastogenesis and bone resorption in psoriatic arthritis. J Clin Invest. 2003, 111: 821-831. 10.1172/JCI200316069.
Article
PubMed Central
CAS
PubMed
Google Scholar
Xing L, Schwarz EM: Circulating osteoclast precursors: a mechanism and a marker of erosive arthritis. Curr Rheumatol Rev. 2005, 1: 21-28. 10.2174/1573397052954127.
Article
CAS
Google Scholar
Battegay EJ, Raines EW, Colbert T, Ross R: TNF-alpha stimulation of fibroblast proliferation. Dependence on platelet-derived growth factor (PDGF) secretion and alteration of PDGF receptor expression. J Immunol. 1995, 154: 6040-6047.
CAS
PubMed
Google Scholar
Su JL, Yang PC, Shih JY, Yang CY, Wei LH, Hsieh CY, Chou CH, Jeng YM, Wang MY, Chang KJ, et al: The VEGF-C/Flt-4 axis promotes invasion and metastasis of cancer cells. Cancer Cell. 2006, 9: 209-223. 10.1016/j.ccr.2006.02.018.
Article
CAS
PubMed
Google Scholar
Roy H, Bhardwaj S, Yla-Herttuala S: Biology of vascular endothelial growth factors. FEBS Lett. 2006, 580: 2879-2887. 10.1016/j.febslet.2006.03.087.
Article
CAS
PubMed
Google Scholar
Yao Z, Xing L, Qin C, Schwarz EM, Boyce BF: Osteoclast precursors induce their differentiation to osteoclasts by interacting with bone matrix and secreting cytokines. JBMR. 2006, 21 (Suppl 2): S262-
Google Scholar
Zhang YH, Heulsmann A, Tondravi MM, Mukherjee A, Abu-Amer Y: Tumor necrosis factor-alpha (TNF) stimulates RANKL-induced osteoclastogenesis via coupling of TNF type 1 receptor and RANK signaling pathways. J Biol Chem. 2001, 276: 563-568. 10.1074/jbc.M008198200.
Article
CAS
PubMed
Google Scholar
Tsai PW, Shiah SG, Lin MT, Wu CW, Kuo ML: Up-regulation of vascular endothelial growth factor C in breast cancer cells by heregulin-beta 1. A critical role of p38/nuclear factor-kappa B signaling pathway. J Biol Chem. 2003, 278: 5750-5759. 10.1074/jbc.M204863200.
Article
CAS
PubMed
Google Scholar
Tammela T, Enholm B, Alitalo K, Paavonen K: The biology of vascular endothelial growth factors. Cardiovasc Res. 2005, 65: 550-563. 10.1016/j.cardiores.2004.12.002.
Article
CAS
PubMed
Google Scholar
Yin G, Liu W, An P, Li P, Ding I, Planelles V, Schwarz EM, Min W: Endostatin gene transfer inhibits joint angiogenesis and pannus formation in inflammatory arthritis. Mol Ther. 2002, 5 (5 Pt 1): 547-554. 10.1006/mthe.2002.0590.
Article
CAS
PubMed
Google Scholar
Olszewski WL, Pazdur J, Kubasiewicz E, Zaleska M, Cooke CJ, Miller NE: Lymph draining from foot joints in rheumatoid arthritis provides insight into local cytokine and chemokine production and transport to lymph nodes. Arthritis Rheum. 2001, 44: 541-549. 10.1002/1529-0131(200103)44:3<541::AID-ANR102>3.0.CO;2-6.
Article
CAS
PubMed
Google Scholar
Huh YM, Kim S, Suh JS, Song H, Song K, Shin KH: The role of popliteal lymph nodes in differentiating rheumatoid arthritis from osteoarthritis by using CE 3D FSPGR MR imaging: relationship of the inflamed synovial volume. Korean J Radiol. 2005, 6: 117-124.
Article
PubMed Central
PubMed
Google Scholar
Goldman J, Le TX, Skobe M, Swartz MA: Overexpression of VEGF-C causes transient lymphatic hyperplasia but not increased lymphangiogenesis in regenerating skin. Circ Res. 2005, 96: 1193-1199. 10.1161/01.RES.0000168918.27576.78.
Article
CAS
PubMed
Google Scholar
Wauke K, Nagashima M, Ishiwata T, Asano G, Yoshino S: Expression and localization of vascular endothelial growth factor-C in rheumatoid arthritis synovial tissue. J Rheumatol. 2002, 29: 34-38.
CAS
PubMed
Google Scholar
Cha HS, Bae EK, Koh JH, Chai JY, Jeon CH, Ahn KS, Kim J, Koh EM: Tumor necrosis factor-alpha induces vascular endothelial growth factor-C expression in rheumatoid synoviocytes. J Rheumatol. 2007, 34: 16-19.
PubMed
Google Scholar
Kerjaschki D: Lymphatic neoangiogenesis in renal transplants: a driving force of chronic rejection?. J Nephrol. 2006, 19: 403-406.
CAS
PubMed
Google Scholar
Tammali R, Ramana KV, Srivastava SK: Aldose reductase regulates TNF-alpha-induced PGE2 production in human colon cancer cells. Cancer Lett. 2007, 252: 299-306. 10.1016/j.canlet.2007.01.001.
Article
PubMed Central
CAS
PubMed
Google Scholar
Timoshenko AV, Chakraborty C, Wagner GF, Lala PK: COX-2-mediated stimulation of the lymphangiogenic factor VEGF-C in human breast cancer. Br J Cancer. 2006, 94: 1154-1163. 10.1038/sj.bjc.6603067.
Article
PubMed Central
CAS
PubMed
Google Scholar
Silverman MD, Haas CS, Rad AM, Arbab AS, Koch AE: The role of vascular cell adhesion molecule 1/very late activation antigen 4 in endothelial progenitor cell recruitment to rheumatoid arthritis synovium. Arthritis Rheum. 2007, 56: 1817-1826. 10.1002/art.22706.
Article
CAS
PubMed
Google Scholar
Bashyam H: Vessel-widening by VEGF. J Exp Med. 2007, 204: 1240-10.1084/jem.2046iti4.
Article
Google Scholar
Braverman IM, Yen A: Microcirculation in psoriatic skin. J Invest Dermatol. 1974, 62: 493-502. 10.1111/1523-1747.ep12681007.
Article
CAS
PubMed
Google Scholar
Ryan TJ: Microcirculation in psoriasis: blood vessels, lymphatics and tissue fluid. Pharmacol Ther. 1980, 10: 27-64. 10.1016/0163-7258(80)90008-X.
Article
CAS
PubMed
Google Scholar
Kovi J, Duong HD, Hoang CT: Ultrastructure of intestinal lymphatics in Crohn's disease. Am J Clin Pathol. 1981, 76: 385-394.
CAS
PubMed
Google Scholar
Cursiefen C, Cao J, Chen L, Liu Y, Maruyama K, Jackson D, Kruse FE, Wiegand SJ, Dana MR, Streilein JW: Inhibition of hemangiogenesis and lymphangiogenesis after normal-risk corneal transplantation by neutralizing VEGF promotes graft survival. Invest Ophthalmol Vis Sci. 2004, 45: 2666-2673. 10.1167/iovs.03-1380.
Article
PubMed
Google Scholar
Kajiya K, Detmar M: An important role of lymphatic vessels in the control of UVB-induced edema formation and inflammation. J Invest Dermatol. 2006, 126: 919-921. 10.1038/sj.jid.5700126.
Article
CAS
PubMed
Google Scholar