McInnes IB, Schett G: Cytokines in the pathogenesis of rheumatoid arthritis. Nat Rev Immunol. 2007, 7: 429-442. 10.1038/nri2094.
Article
CAS
PubMed
Google Scholar
Gaffen SL: The role of interleukin-17 in the pathogenesis of rheumatoid arthritis. Curr Rheumatol Rep. 2009, 11: 365-370. 10.1007/s11926-009-0052-y.
Article
CAS
PubMed
PubMed Central
Google Scholar
Gaffen SL: Structure and signalling in the IL-17 receptor family. Nat Rev Immunol. 2009, 9: 556-567. 10.1038/nri2586.
Article
CAS
PubMed
PubMed Central
Google Scholar
Chen DY, Chen YM, Chen HH, Hsieh CW, Lin CC, Lan JL: Increasing levels of circulating Th17 cells and interleukin-17 in rheumatoid arthritis patients with an inadequate response to anti-TNF-alpha therapy. Arthritis Res Ther. 2011, 13: R126-10.1186/ar3431.
Article
CAS
PubMed
PubMed Central
Google Scholar
Zaba LC, Cardinale I, Gilleaudeau P, Sullivan-Whalen M, Suarez Farinas M, Fuentes-Duculan J, Novitskaya I, Khatcherian A, Bluth MJ, Lowes MA, Krueger JG: Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses. J Exp Med. 2007, 204: 3183-3194. 10.1084/jem.20071094.
Article
CAS
PubMed
PubMed Central
Google Scholar
Ni Mhuircheartaigh OM, Matteson EL, Green AB, Crowson CS: Trends in serious infections in rheumatoid arthritis. J Rheumatol. 2013, 40: 611-616. 10.3899/jrheum.121075.
Article
PubMed
Google Scholar
Listing J, Gerhold K, Zink A: The risk of infections associated with rheumatoid arthritis, with its comorbidity and treatment. Rheumatology (Oxford). 2013, 52: 53-61. 10.1093/rheumatology/kes305.
Article
CAS
Google Scholar
Hueber W, Patel DD, Dryja T, Wright AM, Koroleva I, Bruin G, Antoni C, Draelos Z, Gold MH, Psoriasis Study Group, Durez P, Tak PP, Gomez-Reino JJ, Foster CS, Kim RY, Samson CM, Falk NS, Chu DS, Callanan D, Nguyen QD, Rose K, Haider A, Di Padova F: Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis. Sci Transl Med. 2010, 2: 52ra72-
Article
PubMed
Google Scholar
Patel DD, Lee DM, Kolbinger F, Antoni C: Effect of IL-17A blockade with secukinumab in autoimmune diseases. Ann Rheum Dis. 2013, 72: 116-123.
Article
Google Scholar
Genovese M, Van den Bosch F, Roberson S, Bojin S, Biagini I, Ryan P, Sloan-Lancaster J: LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis. Arthritis Rheum. 2010, 62: 929-939. 10.1002/art.27334.
Article
CAS
PubMed
Google Scholar
Leonardi C, Matheson R, Zachariae C, Cameron G, Li L, Edson-Heredia E, Braun D, Banerjee S: Anti-interleukin-17 monoclonal antibody ixekizumab in chronic plaque psoriasis. N Engl J Med. 2012, 366: 1190-1199. 10.1056/NEJMoa1109997.
Article
CAS
PubMed
Google Scholar
Papp KA, Leonardi C, Menter A, Ortonne JP, Krueger JG, Kricorian G, Aras G, Li J, Russell CB, Thompson EH, Baumgartner S: Brodalumab, an anti-interleukin-17-receptor antibody for psoriasis. N Engl J Med. 2012, 366: 1181-1189. 10.1056/NEJMoa1109017.
Article
CAS
PubMed
Google Scholar
Vautier S, Sousa Mda G, Brown GD: C-type lectins, fungi and Th17 responses. Cytokine Growth Factor Rev. 2010, 21: 405-412. 10.1016/j.cytogfr.2010.10.001.
Article
CAS
PubMed
PubMed Central
Google Scholar
Acosta-Rodriguez EV, Rivino L, Geginat J, Jarrossay D, Gattorno M, Lanzavecchia A, Sallusto F, Napolitani G: Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells. Nat Immunol. 2007, 8: 639-646. 10.1038/ni1467.
Article
CAS
PubMed
Google Scholar
Huppler AR, Bishu S, Gaffen SL: Mucocutaneous candidiasis: the IL-17 pathway and implications for targeted immunotherapy. Arthritis Res Ther. 2012, 14: 217-10.1186/ar3893.
Article
CAS
PubMed
PubMed Central
Google Scholar
Puel A, Picard C, Cypowyj S, Lilic D, Abel L, Casanova JL: Inborn errors of mucocutaneous immunity to Candida albicans in humans: a role for IL-17 cytokines?. Curr Opin Immunol. 2010, 22: 467-474. 10.1016/j.coi.2010.06.009.
Article
CAS
PubMed
PubMed Central
Google Scholar
Strangfeld A, Listing J: Infection and musculoskeletal conditions: bacterial and opportunistic infections during anti-TNF therapy. Best Pract Res Clin Rheumatol. 2006, 20: 1181-1195. 10.1016/j.berh.2006.08.010.
Article
CAS
PubMed
Google Scholar
Ford AC, Peyrin-Biroulet L: Opportunistic infections with anti-tumor necrosis factor-alpha therapy in inflammatory bowel disease: meta-analysis of randomized controlled trials. Am J Gastroenterol. 2013, 108: 1268-1276. 10.1038/ajg.2013.138.
Article
CAS
PubMed
Google Scholar
Brown GD, Denning DW, Gow NA, Levitz SM, Netea MG, White TC: Hidden killers: human fungal infections. Sci Transl Med. 2012, 4: 165rv113-
Article
Google Scholar
Acosta-Rodriguez EV, Napolitani G, Lanzavecchia A, Sallusto F: Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells. Nat Immunol. 2007, 8: 942-949.
Article
CAS
PubMed
Google Scholar
Conti H, Baker O, Freeman A, Jang W, Li R, Holland S, Edgerton M, Gaffen S: New mechanism of oral immunity to mucosal candidiasis in hyper-IgE syndrome. Mucosal Immunol. 2011, 4: 448-455. 10.1038/mi.2011.5.
Article
CAS
PubMed
PubMed Central
Google Scholar
Conti HR, Gaffen SL: Host responses to Candida albicans: Th17 cells and mucosal candidiasis. Microbes Infect. 2010, 12: 518-527. 10.1016/j.micinf.2010.03.013.
Article
CAS
PubMed
PubMed Central
Google Scholar
Dongari-Bagtoglou A, Fidel P: The host cytokine responses and protective immunity in oropharyngeal candidiasis. J Dent Res. 2005, 84: 966-977. 10.1177/154405910508401101.
Article
Google Scholar
Eyre S, Bowes J, Diogo D, Lee A, Barton A, Martin P, Zhernakova A, Stahl E, Viatte S, McAllister K, Amos CI, Padyukov L, Toes RE, Huizinga TW, Wijmenga C, Trynka G, Franke L, Westra HJ, Alfredsson L, Hu X, Sandor C, de Bakker PI, Davila S, Khor CC, Heng KK, Andrews R, Edkins S, Hunt SE, Langford C, Symmons D: High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nat Genet. 2012, 44: 1336-1340. 10.1038/ng.2462.
Article
CAS
PubMed
PubMed Central
Google Scholar
Garg A, Ahmed M, Vallejo A, Ma A, Gaffen S: The deubiquitinase A20 mediates feedback inhibition of interleukin-17 receptor signaling. Sci Signal. 2013, 6: ra44-ra55.
Article
PubMed
PubMed Central
Google Scholar
Cornelissen F, van Hamburg JP, Lubberts E: The IL-12/IL-23 axis and its role in Th17 cell development, pathology and plasticity in arthritis. Curr Opin Investig Drugs. 2009, 10: 452-462.
CAS
PubMed
Google Scholar
Iwakura Y, Ishigame H, Saijo S, Nakae S: Functional specialization of interleukin-17 family members. Immunity. 2011, 34: 149-162. 10.1016/j.immuni.2011.02.012.
Article
CAS
PubMed
Google Scholar
Miossec P, Kolls JK: Targeting IL-17 and TH17 cells in chronic inflammation. Nat Rev Drug Discov. 2012, 11: 763-776. 10.1038/nrd3794.
Article
CAS
PubMed
Google Scholar
Marijnissen RJ, Koenders MI, van de Veerdonk FL, Dulos J, Netea MG, Boots AM, Joosten LA, van den Berg WB: Exposure to Candida albicans polarizes a T-cell driven arthritis model towards Th17 responses, resulting in a more destructive arthritis. PLoS One. 2012, 7: e38889-10.1371/journal.pone.0038889.
Article
CAS
PubMed
PubMed Central
Google Scholar
Miossec P: Interleukin-17 in rheumatoid arthritis: if T cells were to contribute to inflammation and destruction through synergy. Arth Rheum. 2003, 48: 594-601. 10.1002/art.10816.
Article
CAS
Google Scholar
Shen F, Gaffen SL: Structure-function relationships in the IL-17 receptor: implications for signal transduction and therapy. Cytokine. 2008, 41: 92-104. 10.1016/j.cyto.2007.11.013.
Article
CAS
PubMed
PubMed Central
Google Scholar
McGeachy MJ, Bak-Jensen KS, Chen Y, Tato CM, Blumenschein W, McClanahan T, Cua DJ: TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology. Nat Immunol. 2007, 8: 1390-1397. 10.1038/ni1539.
Article
CAS
PubMed
Google Scholar
Ghoreschi K, Laurence A, Yang XP, Tato CM, McGeachy MJ, Konkel JE, Ramos HL, Wei L, Davidson TS, Bouladoux N, Grainger JR, Chen Q, Kanno Y, Watford WT, Sun HW, Eberl G, Shevach EM, Belkaid Y, Cua DJ, Chen W, O'Shea JJ: Generation of pathogenic T(H)17 cells in the absence of TGF-beta signalling. Nature. 2010, 467: 967-971. 10.1038/nature09447.
Article
CAS
PubMed
PubMed Central
Google Scholar
Lee Y, Awasthi A, Yosef N, Quintana FJ, Xiao S, Peters A, Wu C, Kleinewietfeld M, Kunder S, Hafler DA, Sobel RA, Regev A, Kuchroo VK: Induction and molecular signature of pathogenic TH17 cells. Nat Immunol. 2012, 13: 991-999. 10.1038/ni.2416.
Article
CAS
PubMed
PubMed Central
Google Scholar
Conti HR, Shen F, Nayyar N, Stocum E, Sun JN, Lindemann MJ, Ho AW, Hai JH, Yu JJ, Jung JW, Filler SG, Masso-Welch P, Edgerton M, Gaffen SL: Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis. J Exp Med. 2009, 206: 299-311. 10.1084/jem.20081463.
Article
CAS
PubMed
PubMed Central
Google Scholar
Farah C, Hu Y, Riminton S, Ashman R: Distinct roles for interleukin-12p40 and tumour necrosis factor in resistance to oral candidiasis defined by gene targeting. Oral Microbiol Immunol. 2006, 21: 252-255. 10.1111/j.1399-302X.2006.00288.x.
Article
CAS
PubMed
Google Scholar