Aviña-Zubieta JA, Choi HK, Sadatsafavi M, Etminan M, Esdaile JM, Lacaille D. Risk of cardiovascular mortality in patients with rheumatoid arthritis: a meta-analysis of observational studies. Arthritis Rheum. 2008;59:1690–7.
Article
PubMed
Google Scholar
de Pablo P, Chapple ILC, Buckley CD, Dietrich T. Periodontitis in systemic rheumatic diseases. Nat Rev Rheumatol. 2009;5:218–24.
Article
PubMed
Google Scholar
Potempa J, Mydel P, Koziel J. The case for periodontitis in the pathogenesis of rheumatoid arthritis. Nat Rev Rheumatol. 2017;13:606–20.
Article
PubMed
CAS
Google Scholar
Brink M, Hansson M, Mathsson L, Jakobsson P-J, Holmdahl R, Hallmans G, et al. Multiplex analyses of antibodies against citrullinated peptides in individuals prior to development of rheumatoid arthritis. Arthritis Rheum. 2013;65:899–910.
Article
PubMed
CAS
Google Scholar
Rakieh C, Rakieh C, Nam JL, Nam JL, Hunt L, Hunt L, et al. Predicting the development of clinical arthritis in anti-CCP positive individuals with non-specific musculoskeletal symptoms: a prospective observational cohort study. Ann Rheum Dis. 2015;74:1659–66.
Article
PubMed
CAS
Google Scholar
Katchamart W, Koolvisoot A, Aromdee E, Chiowchanwesawakit P, Muengchan C. Associations of rheumatoid factor and anti-citrullinated peptide antibody with disease progression and treatment outcomes in patients with rheumatoid arthritis. Rheumatol Int. 2015;35:1693–9.
Article
PubMed
CAS
Google Scholar
Lee DM, Phillips R, Hagan EM, Chibnik LB, Costenbader KH, Schur PH. Quantifying anti-cyclic citrullinated peptide titres: clinical utility and association with tobacco exposure in patients with rheumatoid arthritis. Ann Rheum Dis. 2009;68:201–8.
Article
PubMed
CAS
Google Scholar
Roberts FA, Darveau RP. Microbial protection and virulence in periodontal tissue as a function of polymicrobial communities: symbiosis and dysbiosis. Periodontol 2000. 2015;69:18–27.
Article
PubMed
PubMed Central
Google Scholar
Hajishengallis G. Immunomicrobial pathogenesis of periodontitis: keystones, pathobionts, and host response. Trends Immunol. 2014;35:3–11.
Article
PubMed
CAS
Google Scholar
Mikuls TR, Payne JB, Yu F, Thiele GM, Reynolds RJ, Cannon GW, et al. Periodontitis and porphyromonas gingivalisin patients with rheumatoid arthritis. Arthritis Rheum. 2014;66:1090–100.
Article
Google Scholar
Ziebolz D, Pabel SO, Lange K, Krohn-Grimberghe B, Hornecker E, Mausberg RF. Clinical periodontal and microbiologic parameters in patients with rheumatoid arthritis. J Periodontol. 2011;82:1424–32.
Article
PubMed
CAS
Google Scholar
Nesse W, Nesse W, Westra J, Westra J, van der Wal JE, van der Wal JE, et al. The periodontium of periodontitis patients contains citrullinated proteins which may play a role in ACPA (anti-citrullinated protein antibody) formation. J Clin Periodontol. 2012;39:599–607.
Article
PubMed
CAS
Google Scholar
Courbon G, Rinaudo-Gaujous M, Blasco-Baque V, Auger I, Caire R, Mijola L, et al. Porphyromonas gingivalis experimentally induces periodontis and an anti-CCP2-associated arthritis in the rat. Ann Rheum Dis. 2019;78:594–99.
Johansson L, Sherina N, Kharlamova N, Potempa B, Larsson B, Israelsson L, et al. Concentration of antibodies against Porphyromonas gingivalis is increased before the onset of symptoms of rheumatoid arthritis. Arthritis Res Ther. 2016;18:201.
Article
PubMed
PubMed Central
CAS
Google Scholar
Mikuls TR, Thiele GM, Deane KD, Payne JB, O'Dell JR, Yu F, et al. Porphyromonas gingivalis and disease-related autoantibodies in individuals at increased risk of rheumatoid arthritis. Arthritis Rheum. 2012;64:3522–30.
Article
PubMed
CAS
Google Scholar
Demmer RT, Molitor JA, Jacobs DR Jr, Michalowicz BS. Periodontal disease, tooth loss and incident rheumatoid arthritis: results from the First National Health and Nutrition Examination Survey and its epidemiological follow-up study. J Clin Periodontol. 2011;38:998–1006.
Article
PubMed
PubMed Central
Google Scholar
Dissick A, Redman RS, Jones M, Rangan BV, Reimold A, Griffiths GR, et al. Association of periodontitis with rheumatoid arthritis: a pilot study. J Periodontol. 2010;81:223–30.
Article
PubMed
Google Scholar
de Pablo P, Dietrich T, McAlindon TE. Association of periodontal disease and tooth loss with rheumatoid arthritis in the US population. J Rheumatol. 2008;35:70–6.
PubMed
Google Scholar
Kaur S, White S, Bartold PM. Periodontal disease and rheumatoid arthritis: a systematic review. J Dent Res. 2013;92:399–408.
Article
PubMed
CAS
Google Scholar
Kim J-H, Choi IA, Lee JY, Kim K-H, Kim S, Koo K-T, et al. Periodontal pathogens and the association between periodontitis and rheumatoid arthritis in Korean adults. J Periodontal Implant Sci. 2018;48:347–59.
Article
PubMed
PubMed Central
CAS
Google Scholar
Rodríguez-Lozano B, González-Febles J, Garnier-Rodríguez JL, Dadlani S, Bustabad-Reyes S, Sanz M, et al. Association between severity of periodontitis and clinical activity in rheumatoid arthritis patients: a case-control study. Arthritis Res Ther. 2019;21:27.
Article
PubMed
PubMed Central
Google Scholar
de Smit M, Westra J, Vissink A, Doornbos-van der Meer B, Brouwer E, van Winkelhoff AJ. Periodontitis in established rheumatoid arthritis patients: a cross-sectional clinical, microbiological and serological study. Arthritis Res Ther. 2012;14:R222.
Article
PubMed
PubMed Central
Google Scholar
Lappin DF, Apatzidou D, Quirke A-M, Oliver-Bell J, Butcher JP, Kinane DF, et al. Influence of periodontal disease, Porphyromonas gingivalis and cigarette smoking on systemic anti-citrullinated peptide antibody titres. J Clin Periodontol. 2013;40:907–15.
Article
PubMed
CAS
Google Scholar
de Pablo P, Dietrich T, Chapple ILC, Milward M, Chowdhury M, Charles PJ, et al. The autoantibody repertoire in periodontitis: a role in the induction of autoimmunity to citrullinated proteins in rheumatoid arthritis? Ann Rheum Dis. 2014;73:580–6.
Article
PubMed
CAS
Google Scholar
Gonzalez SM, Payne JB, Yu F, Thiele GM, Erickson AR, Johnson PG, et al. Alveolar bone loss is associated with circulating anti-citrullinated protein antibody (ACPA) in patients with rheumatoid arthritis. J Periodontol. 2015;86:222–31.
Article
PubMed
CAS
Google Scholar
Lee JY, Lee JY, Choi IA, Choi IA, Kim J-H, Kim J-H, et al. Association between anti-Porphyromonas gingivalis or anti-α-enolase antibody and severity of periodontitis or rheumatoid arthritis (RA) disease activity in RA. BMC Musculoskelet Disord. 2015;16:190.
Article
PubMed
PubMed Central
CAS
Google Scholar
Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, Bingham CO, et al. 2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Arthritis Rheum. 2010;62:2569–81.
Article
PubMed
Google Scholar
Herrera D, Sanz M, Jepsen S, Needleman I, Roldán S. A systematic review on the effect of systemic antimicrobials as an adjunct to scaling and root planing in periodontitis patients. J Clin Periodontol. 2002;29:136–59.
Article
PubMed
Google Scholar
Mavrogiannis M, Mavrogiannis M, Ellis JS, Ellis JS, Thomason JM, Thomason JM, et al. The management of drug-induced gingival overgrowth. J Clin Periodontol. 2006;33:434–9.
Article
PubMed
CAS
Google Scholar
Prevoo ML, van 't Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL. Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum. 1995;38:44–8.
Article
PubMed
CAS
Google Scholar
Smolen JS, Breedveld FC, Schiff MH, Kalden JR, Emery P, Eberl G, et al. A simplified disease activity index for rheumatoid arthritis for use in clinical practice. Rheumatology (Oxford). 2003;42:244–57.
Article
CAS
Google Scholar
Silness J, Löe H. Periodontal disease in pregnancy. II. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand. 1964;22:121–35.
Article
PubMed
CAS
Google Scholar
Ainamo J, Bay I. Problems and proposals for recording gingivitis and plaque. Int Dent J. 1975;25:229–35.
PubMed
CAS
Google Scholar
Tonetti MS, Claffey N, Claffey N, European Workshop in Periodontology group C, European Workshop in Periodontology group C. Advances in the progression of periodontitis and proposal of definitions of a periodontitis case and disease progression for use in risk factor research. Group C consensus report of the 5th European Workshop in Periodontology. J Clin Periodontol. 2005;32(Suppl 6):210–3.
Article
PubMed
Google Scholar
Tonetti MS, Greenwell H, Kornman KS. Staging and grading of periodontitis: framework and proposal of a new classification and case definition. J Clin Periodontol. 2018;45:S149–61.
Article
PubMed
Google Scholar
Cohen S, Kamarck T, Mermelstein R. A global measure of perceived stress. J Health Soc Behav. 1983;24:385–96.
Article
PubMed
CAS
Google Scholar
Remor E. Psychometric properties of a European Spanish version of the Perceived Stress Scale (PSS). Span J Psychol. 2006;9:86–93.
Article
PubMed
Google Scholar
Graffar M. Une methode de classification sociales d’echantillons de population. Courrier. 1956;6:455–9.
Google Scholar
Molitor JA, Alonso A, Wener MH, Michalowics BS, Gersuk VH. Moderate to severe periodontitis increases risk of rheumatoid arthritis in non-smokers and is associated with elevated ACPA titers: The ARIC Study. Arthritis Rheum. 2009;60:1160.
Article
Google Scholar
Konig MF, Abusleme L, Reinholdt J, Palmer RJ, Teles RP, Sampson K, et al. Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis. Sci Transl Med. 2016;8:369ra176.
Article
PubMed
PubMed Central
CAS
Google Scholar
Mankia K, Cheng Z, Do T, Hunt L, Meade J, Kang J, et al. Prevalence of periodontal disease and periodontopathic bacteria in anti-cyclic citrullinated protein antibody-positive at-risk adults without arthritis. JAMA Netw Open. 2019;2:e195394.
Article
PubMed
PubMed Central
Google Scholar
Henderson B, Ward JM, Ready D. Aggregatibacter (Actinobacillus) actinomycetemcomitans: a triple A* periodontopathogen? Periodontol 2000. 2010;54:78–105.
Article
PubMed
Google Scholar
Farias BC, Souza PRE, Ferreira B, Melo RSA, Machado FB, Gusmão ES, et al. Occurrence of periodontal pathogens among patients with chronic periodontitis. Braz J Microbiol. 2012;43:909–16.
Article
PubMed
PubMed Central
CAS
Google Scholar
Polak D, Polak D, Wilensky A, Wilensky A, Shapira L, Halabi A, et al. Mouse model of experimental periodontitis induced by Porphyromonas gingivalis/Fusobacterium nucleatuminfection: bone loss and host response. J Clin Periodontol. 2009;36:406–10.
Article
PubMed
Google Scholar
Makrygiannakis D, Hermansson M, Nicholas AP, Zendman AJW, Eklund A, Grunewald J, et al. Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells. Ann Rheum Dis. 2008;67:1488–92.
Article
PubMed
CAS
Google Scholar
Martinez-Canut P, Llobell A, Romero A. Predictors of long-term outcomes in patients undergoing periodontal maintenance. J Clin Periodontol. 2017;44:620–31.
Article
PubMed
PubMed Central
Google Scholar
Beyer K, Zaura E, Brandt BW, Buijs MJ, Brun JG, Crielaard W, et al. Subgingival microbiome of rheumatoid arthritis patients in relation to their disease status and periodontal health. PLoS One. 2018;13:e0202278–18.
Article
PubMed
PubMed Central
CAS
Google Scholar
Seror R, Seror R, Le Gall-David S, Le Gall-David S, Bonnaure-Mallet M, Bonnaure-Mallet M, et al. Association of anti-porphyromonas gingivalis antibody titers with nonsmoking status in early rheumatoid arthritis: results from the prospective French cohort of patients with early rheumatoid arthritis. Arthritis Rheumatol. 2015;67:1729–37.
Article
PubMed
CAS
Google Scholar