Volume 14 Supplement 3

Lupus 2012: New targets, new approaches

Meeting abstracts

Edited by Peter E Lipsky, John M Esdaile, Matthew H Liang and Paul R Fortin

Lupus 2012: New targets, new approaches.

Whistler, Canada27-30 September 2012

Page 1 of 2

Epigenetics and lupus

Authors: B Richardson

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A1

Content type: Meeting abstract Published on: 27 September 2012
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Follicular helper T Cells and the B cells they help

Authors: A Poholek, J-Y Choi, S Hernandez, J Weinstein, S Kim, V Bunin, J Odegard, L DiPlacido and J Craft

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A2

Content type: Meeting abstract Published on: 27 September 2012
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Longitudinal analysis of mRNA transcripts and plasma proteins to define a biomarker associated with lupus disease activity

Authors: M Olferiev, W-T Huang, KA Kirou, E Gkrouzman, D Lundsgaard, KS Frederiksen, J Fleckner and MK Crow

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A3

Content type: Meeting abstract Published on: 27 September 2012
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New therapies

Authors: David Wofsy

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A4

Content type: Meeting abstract Published on: 27 September 2012
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MicroRNA-3148 modulates differential gene expression of the SLE-associated TLR7 variant

Authors: Y Deng, J Zhao, D Sakurai, KM Kaufman, JC Edberg, RP Kimberly, DL Kamen, GS Gilkeson, CO Jacob, RH Scofield, CD Langefeld, JA Kelly, ME Alarcón-Riquelme, JB Harley, TJ Vyse, BI Freedman…

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A5

Content type: Meeting abstract Published on: 27 September 2012
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Differential DNA methylation associated with anti-dsDNA autoantibody production in systemic lupus erythematosus

Authors: SA Chung, J French, KE Taylor, E Elboudwarej, HL Quach, LF Barcellos and LA Criswell

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A6

Content type: Meeting abstract Published on: 27 September 2012
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Area-level socioeconomic status and variation in medication use among Medicaid enrollees with incident systemic lupus erythematosus, 2000 to 2004

Authors: CH Feldman, LT Hiraki, J Lui, GS Alarcón, MA Fischer, J Yazdany and KH Costenbader

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A7

Content type: Meeting abstract Published on: 27 September 2012
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SLE risk alleles and cell development and activation

Authors: SJ Kim, N Manjarrez Orduno, PK Gregersen and B Diamond

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A8

Content type: Meeting abstract Published on: 27 September 2012
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Genetic-epigenetic interaction in lupus

Authors: AH Sawalha

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A9

Content type: Meeting abstract Published on: 27 September 2012
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Serum chemokine levels predict flares of disease activity in two independent systemic lupus erythematosus cohorts

Authors: H Bilgic, T Koeuth, J Wilson, M Petri and E Baechler Gillespie

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A10

Content type: Meeting abstract Published on: 27 September 2012
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Major congenital anomalies in children born to women with systemic lupus erythematosus

Authors: E Vinet, CA Pineau, AE Clarke, M Kaouache, C Gordon, R Platt and S Bernatsky

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A11

Content type: Meeting abstract Published on: 27 September 2012
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Contemporary estimates of the risk of end-stage renal disease in the first decade of proliferative lupus nephritis

Authors: MM Ward and M Tektonidou

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A12

Content type: Meeting abstract Published on: 27 September 2012
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Impact of systemic lupus erythematosus organ damage on unemployment or disability from a population-based cohort

Authors: SS Lim, M Agan and CM Drenkard

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A13

Content type: Meeting abstract Published on: 27 September 2012
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Population-based study of preventable infections in hospitalized patients with systemic lupus erythematosus

Authors: CE Barber, C Barnabe, D Marshall and J Esdaile

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A14

Content type: Meeting abstract Published on: 27 September 2012
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Lung cancer in systemic lupus erythematosus

Authors: M Kale, R Ramsey-Goldman, S Bernatsky, MB Urowitz, D Gladman, PR Fortin, M Petri, E Yelin, S Manzi, S Edworthy, O Nived, S-C Bae, D Isenberg, A Rahman, JG Hanly, C Gordon…

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A15

Content type: Meeting abstract Published on: 27 September 2012
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Lymphoma risk in systemic lupus: effects of treatment versus disease activity

Authors: AE Clarke, S Bernatsky, KH Costenbader, MB Urowitz, DD Gladman, PR Fortin, M Petri, S Manzi, DA Isenberg, A Rahman, D Wallace, C Gordon, C Peschken, MA Dooley, EM Ginzler, C Aranow…

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A16

Content type: Meeting abstract Published on: 27 September 2012
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Usual source of care and geographic region are largest predictors of healthcare quality for incident lupus nephritis in US Medicaid recipients

Authors: J Yazdany, C Feldman, J Liu, MM Ward, MA Fischer and KH Costenbader

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A17

Content type: Meeting abstract Published on: 27 September 2012
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Neuropsychiatric events in SLE: determination of attribution and assessment of outcome

Authors: JG Hanly

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A18

Content type: Meeting abstract Published on: 27 September 2012
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Seafood consumption and persistent organic pollutants as triggers of autoimmunity among Gullah African Americans

Authors: DL Kamen, MM Peden-Adams, JE Vena, GS Gilkeson, TC Hulsey, L Moultrie and BE Stevens

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A19

Content type: Meeting abstract Published on: 27 September 2012
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Rising prevalence of systemic autoimmune rheumatic disease: increased awareness, increased disease or increased survival?

Authors: CA Peschken and CA Hitchon

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A20

Content type: Meeting abstract Published on: 27 September 2012
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Soluble E-selectin may predict progression of subclinical atherosclerosis, as measured by coronary artery calcium score and aorta calcium score, in women with systemic lupus erythematosus

Authors: A Lertratanakul, P Wu, A Dyer, W Pearce, G Kondos, D Edmundowicz, J Carr and R Ramsey-Goldman

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A21

Content type: Meeting abstract Published on: 27 September 2012
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Serum α-chlorofatty acid as a biomarker for baseline subclinical cardiovascular disease in systemic lupus erythematosus

Authors: MA Mahieu, C Guild, CJ Albert, G Kondos, J Carr, D Edmundowicz, DA Ford and R Ramsey-Goldman

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A22

Content type: Meeting abstract Published on: 27 September 2012
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Differing environmental risk factors for membranous versus proliferative lupus nephritis

Authors: MA Dooley, CG Parks and GS Cooper

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A23

Content type: Meeting abstract Published on: 27 September 2012
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B cells at the adaptive-innate immune system interface in SLE

Authors: JH Anolik, A Palanichamy, J Bauer, J Barnard, J Biear, R Dedrick, I Sanz, J Liesveld and E Baechler

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A24

Content type: Meeting abstract Published on: 27 September 2012
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In situ cognate interactions between T-follicular helper cells and B cells characterize severe tubulointerstitial inflammation in human lupus nephritis

Authors: MR Clark, M Giger, Y Jiang and V Liarski

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A25

Content type: Meeting abstract Published on: 27 September 2012
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SLE patients and autoantibody-positive healthy individuals display unique cytokine profiles: shared features of inflammation as well as select features of immunosuppression in autoantibody-positive healthy individuals

Authors: LL Ritterhouse, HT Maecker, CG Fathman, JT Merrill, JM Guthridge and JA James

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A26

Content type: Meeting abstract Published on: 27 September 2012
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Regulatory natural autoantibodies suppress inflammation and SLE disease activity

Authors: GJ Silverman, J Vas and C Grönwall

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A27

Content type: Meeting abstract Published on: 27 September 2012
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Genetic polymorphisms leading to altered T-cell and dendritic cell function cooperate to produce expansion of proinflammatory T-cell subsets in NZB c1 congenic mice

Authors: N Talaei, C Landolt-Marticorena, B Noamani, E Pau, N-H Chang and JE Wither

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A28

Content type: Meeting abstract Published on: 27 September 2012
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Abstract withdrawn

Authors:

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A29

Content type: Meeting abstract Published on: 27 September 2012
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Dysregulation of the serine/threonine phosphatase PP2A contributes to autoimmunity

Authors: JC Crispín

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A30

Content type: Meeting abstract Published on: 27 September 2012
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Spontaneous aggregation of the anti-viral MAVS protein in systemic lupus erythematosus: a possible cause of excessive type I interferon production

Authors: PL Cohen, B Hilliard and W-H Shao

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A31

Content type: Meeting abstract Published on: 27 September 2012
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IRF5 expression profiling in SLE patients: new leads to a pathogenic signature?

Authors: BJ Barnes, RC Stone, P Du and D Feng

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A32

Content type: Meeting abstract Published on: 27 September 2012
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Role of MIF gene polymorphisms in systemic lupus erythematosus and prospects for therapeutic intervention

Authors: R Bucala

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A33

Content type: Meeting abstract Published on: 27 September 2012
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Interplay of neutrophils and type I interferons in the development of end-organ damage in SLE

Authors: MJ Kaplan

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A34

Content type: Meeting abstract Published on: 27 September 2012
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Metabolic control of systemic lupus erythematosus: convergence of genetic and environmental factors on mitochondrial dysfunction and mTOR reveal treatment targets in lupus

Authors: A Perl

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A35

Content type: Meeting abstract Published on: 27 September 2012
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Microparticles as autoantigens in human and murine lupus

Authors: A Ullal and DS Pisetsky

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A36

Content type: Meeting abstract Published on: 27 September 2012
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Innate sensors for nucleic acids and lupus pathogenesis

Authors: AN Theofilopoulos, R Gonzalez-Quintial, Y-T Koh, R Baccala and DH Kono

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A37

Content type: Meeting abstract Published on: 27 September 2012
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Evaluating the B-cell C3d:CR2 innate-adaptive immune interaction as a therapeutic target in lupus

Authors: VM Holers, JM Thurman, JP Hannan and L Kulik

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A38

Content type: Meeting abstract Published on: 27 September 2012
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PROMISSE: progress in understanding pregnancy complications in patients with SLE

Authors: JE Salmon

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A39

Content type: Meeting abstract Published on: 27 September 2012
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Complement deficiencies and susceptibility to systemic lupus erythematosus revisited

Authors: KB Elkon, DM Santer and A Wiedeman

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A40

Content type: Meeting abstract Published on: 27 September 2012
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Connecting the molecular dots from inaccessible antigen to organ injury in the pathogenesis of cardiac manifestations of neonatal lupus

Authors: JP Buyon

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A41

Content type: Meeting abstract Published on: 27 September 2012
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MicroRNAs in innate immune responses and autoimmune diseases

Authors: EKL Chan

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A42

Content type: Meeting abstract Published on: 27 September 2012
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Skin-antigen specific antibodies are detected in UV irradiation and TLR7 agonist induced lupus-like disease in autoimmune prone NOD mice and in pediatric SLE

Authors: M Ghoreishi, L Tucker and JP Dutz

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A43

Content type: Meeting abstract Published on: 27 September 2012
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SLE: insights from array-based proteomics

Authors: T Wu, Y Du, L Davis and C Mohan

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A44

Content type: Meeting abstract Published on: 27 September 2012
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Renal flare as a biomarker of incident and progressive chronic kidney disease in patients with lupus nephritis

Authors: S Parikh, A McKinley and BH Rovin

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A45

Content type: Meeting abstract Published on: 27 September 2012
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Cytokine profiles of lupus patients with or without nephritis

Authors: BH Rovin, H Song, CL Hines and X Zhang

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A46

Content type: Meeting abstract Published on: 27 September 2012
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Which lupus trial endpoints best reflect clinical judgment or biomarker improvement?

Authors: A Thanou, M Munroe, S Kamp, F Carthen, JA James and JT Merrill

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A47

Content type: Meeting abstract Published on: 27 September 2012
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'MiLES' population-based survey of the incidence and prevalence of systemic lupus erythematosus in Southeastern Michigan

Authors: EC Somers, W Marder, P Cagnoli, EE Lewis, P DeGuire, C Gordon, CG Helmick, L Wang, JJ Wing, JP Dhar, J Liesen and WJ McCune

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A48

Content type: Meeting abstract Published on: 27 September 2012
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Sociodemographic characteristics of SLE patients in a large metropolitan area with a high Afro-Caribbean population

Authors: J Cabas-Vargas, NM Patel, J Cohen and EM Ginzler

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A49

Content type: Meeting abstract Published on: 27 September 2012
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High score on PREDICTS is associated with 10-fold increased odds for the progression of subclinical atherosclerosis in SLE

Authors: M McMahon, Lori Sahakian, J Grossman, B Skaggs, J Fitzgerald, C Charles-Schoeman, N Ragavendra, A Gorn, G Karpouzas, M Weisman, D Wallace and B Hahn

Citation: Arthritis Research & Therapy 2012 14(Suppl 3):A50

Content type: Meeting abstract Published on: 27 September 2012
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Lupus 2012: New targets, new approaches

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