Volume 5 Supplement 3

3rd World Congress of the Global Arthritis Research Network (GARN): International Arthritis Summit

Meeting abstracts

3rd World Congress of the Global Arthritis Research Network (GARN): International Arthritis Summit.

Summit Hall at Sheraton Resorts in Miyazaki, Japan14-17 September 2003

Page 1 of 4

DNA degradation during apoptotic cell death

Authors: S Nagata

Citation: Arthritis Res Ther 2003 5(Suppl 3):1

Content type: Oral presentation Published on: 12 September 2003
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Paracrine pathways of cartilage destruction in osteoarthritis

Authors: S Abramson, M Attur, M Dave, M Leung, J Patel, P Gomez and A Amin

Citation: Arthritis Res Ther 2003 5(Suppl 3):2

Content type: Oral presentation Published on: 12 September 2003
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Fifty years' experience in resarch for pathogenesis of rheumatoid arthritis.

Authors: NJ Zvaifler

Citation: Arthritis Res Ther 2003 5(Suppl 3):3

Content type: Oral presentation Published on: 12 September 2003
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Interferons and IRF/Stat transcription factors in the regulation of immunity, oncogenesis and bone remodeling

Authors: T Taniguchi, A Takaoka, H Takayanagi and K Honda

Citation: Arthritis Res Ther 2003 5(Suppl 3):4

Content type: Oral presentation Published on: 12 September 2003
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Delineating biologic pathways involved in skeletal growth and homeostasis through the study of rare Mendelian diseases that affect bones and joints

Authors: M Warman

Citation: Arthritis Res Ther 2003 5(Suppl 3):5

Content type: Oral presentation Published on: 12 September 2003
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Assessing the burden of musculoskeletal conditions: a joint World Health Organization–Bone and Joint Decade project

Authors: N Khaltaev, B Pfleger, AD Woolf, C Mathers, K Akesson, JM Hazes and D Symmons

Citation: Arthritis Res Ther 2003 5(Suppl 3):174

Content type: Oral presentation Published on: 12 September 2003
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Fortieth Anniversary of APLAR

Authors: P Pispati

Citation: Arthritis Res Ther 2003 5(Suppl 3):175

Content type: Oral presentation Published on: 12 September 2003
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Premise: traditional disease-modifying antirheumatic drugs are less effective and safe than targeted therapy with biologic response modifiers in rheumatoid arthritis

Authors: R Fleischmann

Citation: Arthritis Res Ther 2003 5(Suppl 3):6

Content type: Oral presentation Published on: 12 September 2003
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The use of animal models to find and understand arthritis genes

Authors: R Holmdahl

Citation: Arthritis Res Ther 2003 5(Suppl 3):7

Content type: Oral presentation Published on: 12 September 2003
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Synovial mast cells require C5a receptor (CD88) for arthritis induction

Authors: D Lee, M Brenner, C Gerard, C Benoist, D Mathis and G Watts

Citation: Arthritis Res Ther 2003 5(Suppl 3):8

Content type: Oral presentation Published on: 12 September 2003
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Albumin-based drug delivery as novel therapeutic approach for rheumatoid arthritis

Authors: A Wunder, U Muller-Ladner, E Stelzer, E Neumann, H Sinn, S Gay and C Fiehn

Citation: Arthritis Res Ther 2003 5(Suppl 3):9

Content type: Oral presentation Published on: 12 September 2003
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SKG mice, a new genetic model of rheumatoid arthritis

Authors: S Sakaguchi, T Takahashi, H Hata, T Nomura and N Sakaguchi

Citation: Arthritis Res Ther 2003 5(Suppl 3):10

Content type: Oral presentation Published on: 12 September 2003
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The role of IL-17 in the development of arthritis in mouse models

Authors: Y Iwakura, S Nakae, R Horai and S Saijo

Citation: Arthritis Res Ther 2003 5(Suppl 3):11

Content type: Oral presentation Published on: 12 September 2003
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Cytokine production by dendritic cells genetically engineered to express IL-4: induction of Th2 responses and differential regulation of IL-12 and IL-23 synthesis

Authors: D Fox, Y Morita, R Gupta, K Seidl and K McDonagh

Citation: Arthritis Res Ther 2003 5(Suppl 3):12

Content type: Oral presentation Published on: 12 September 2003
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GRAIL: a gene related to anergy in lymphocytes

Authors: G Fathman, L Soares, N Anandasabapathy and C Seroogy

Citation: Arthritis Res Ther 2003 5(Suppl 3):13

Content type: Oral presentation Published on: 12 September 2003
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Characterization of signaling complexes at the T-cell antigen receptor

Authors: L Samelson

Citation: Arthritis Res Ther 2003 5(Suppl 3):14

Content type: Oral presentation Published on: 12 September 2003
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Toll-like receptor family: receptors essential for microbial recognition and immune responses

Authors: S Akira, M Yamamoto and K Takeda

Citation: Arthritis Res Ther 2003 5(Suppl 3):15

Content type: Oral presentation Published on: 12 September 2003
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The actions of BAFF in B-lymphocyte maturation and its effects on the development of autoimmune disease

Authors: F Melchers

Citation: Arthritis Res Ther 2003 5(Suppl 3):16

Content type: Oral presentation Published on: 12 September 2003
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Proteomic surveillance of autoimmunity in osteoarthritis

Authors: T Kato, Y Xiang, T Sekine, H Nakamura, S Imajoh-Ohmi, H Fukuda and K Nishioka

Citation: Arthritis Res Ther 2003 5(Suppl 3):17

Content type: Oral presentation Published on: 12 September 2003
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Regulation of synovial cell function by adenovirus vector-mediated gene transduction

Authors: S Tanaka, H Seto, H Oda and K Nakamura

Citation: Arthritis Res Ther 2003 5(Suppl 3):18

Content type: Oral presentation Published on: 12 September 2003
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Role of BH3-only protein Bim in autoimmune and degenerative diseases

Authors: P Bouillet, S Cory, J Adams and A Strasser

Citation: Arthritis Res Ther 2003 5(Suppl 3):19

Content type: Oral presentation Published on: 12 September 2003
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Regulation of RANKL signaling in arthritic bone destruction

Authors: H Takayanagi

Citation: Arthritis Res Ther 2003 5(Suppl 3):20

Content type: Oral presentation Published on: 12 September 2003
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Transcription mechanism of chondrogenesis

Authors: H Asahara

Citation: Arthritis Res Ther 2003 5(Suppl 3):21

Content type: Oral presentation Published on: 12 September 2003
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Cellular therapies in musculoskeletal diseases: synovial-derived mesenchymal stem cells

Authors: F Luyten

Citation: Arthritis Res Ther 2003 5(Suppl 3):22

Content type: Oral presentation Published on: 12 September 2003
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Role of bone morphogenetic protein signals during skeletal development

Authors: N Tsumaki, M Horiki, T Kimura and H Yoshikawa

Citation: Arthritis Res Ther 2003 5(Suppl 3):23

Content type: Oral presentation Published on: 12 September 2003
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Implication of Synoviolin in pathogenesis of arthropathy

Authors: T Nakajima

Citation: Arthritis Res Ther 2003 5(Suppl 3):24

Content type: Oral presentation Published on: 12 September 2003
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Cyclin kinase inhibitors and interferons in lupus

Authors: A Theofilopoulos

Citation: Arthritis Res Ther 2003 5(Suppl 3):25

Content type: Oral presentation Published on: 12 September 2003
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Origins of systemic lupus erythematosus: genes, environment, and host immune response

Authors: JB Harley, JA Kelly and JA James

Citation: Arthritis Res Ther 2003 5(Suppl 3):26

Content type: Oral presentation Published on: 12 September 2003
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Analysis of B-cell subpopulations in systemic lupus erythematosus

Authors: T Dorner, A Jacobi, M Odendahl, GR Burmester, A Radbruch, G Valet and PE Lipsky

Citation: Arthritis Res Ther 2003 5(Suppl 3):27

Content type: Oral presentation Published on: 12 September 2003
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Antiphospholipid antibodies and thrombosis: pathogenesis of antiphospholipid syndrome

Authors: T Koike

Citation: Arthritis Res Ther 2003 5(Suppl 3):28

Content type: Oral presentation Published on: 12 September 2003
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A Phase I trial of B-cell depletion with anti-CD20 monoclonal antibody (rituximab) in the treatment of systemic lupus erythematosus

Authors: R Eisenberg, D Albert, J Stansberry, D Tsai, S Kolasinski and S Khan

Citation: Arthritis Res Ther 2003 5(Suppl 3):29

Content type: Oral presentation Published on: 12 September 2003
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Failure of receptor revision in the autoreactive B cells in patients with systemic lupus erythematosus

Authors: H Yoshikawa, H Nagafuchi, M Kurokawa, T Sakane and N Suzuki

Citation: Arthritis Res Ther 2003 5(Suppl 3):30

Content type: Oral presentation Published on: 12 September 2003
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Chemokines in rheumatoid arthritis: novel, potential therapeutic targets of the CCR2 chemokine receptor signaling pathway

Authors: K Matsushima, Y Terashima and M Haino

Citation: Arthritis Res Ther 2003 5(Suppl 3):31

Content type: Oral presentation Published on: 12 September 2003
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Effect of the combination of the proinflammatory cytokines IL-1, tumor necrosis factor-α and IL-17

Authors: P Miossec, C Granet and G Chevrel

Citation: Arthritis Res Ther 2003 5(Suppl 3):32

Content type: Oral presentation Published on: 12 September 2003
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Human adipose tissue is an important novel source of IL-1Ra: a new connection between immuno-inflammatory diseases and lipid metabolism

Authors: J Dayer and C Meier

Citation: Arthritis Res Ther 2003 5(Suppl 3):33

Content type: Oral presentation Published on: 12 September 2003
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IFN-β for the treatment of rheumatoid arthritis?

Authors: P Tak, J van Holten, K Reedquist, P Sattonet-Roche, T Smeets, M Vervoordeldonk and C Plater-Zyberk

Citation: Arthritis Res Ther 2003 5(Suppl 3):34

Content type: Oral presentation Published on: 12 September 2003
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PPARγ ligands inhibit catabolic and inflammatory responses in articular joint cells

Authors: H Fahmi, J-P Pelletier, F Mineau and J Martel-Pelletier

Citation: Arthritis Res Ther 2003 5(Suppl 3):35

Content type: Oral presentation Published on: 12 September 2003
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The role of mPGES-1 for prostaglandin E₂ production in primary human synovial cells

Authors: L Crofford, M Qian, A Sampey, V Lath, S Guo, M Peters-Golden and M Goldring

Citation: Arthritis Res Ther 2003 5(Suppl 3):36

Content type: Oral presentation Published on: 12 September 2003
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IL-21R mRNA is overexpressed in systemic sclerosis and contributes to the epidermal/dermal cross-talk

Authors: O Distler, J Distler, A Hirth, U Müller-Ladner, M Matucci-Cerinic, H Lorenz and S Gay

Citation: Arthritis Res Ther 2003 5(Suppl 3):37

Content type: Oral presentation Published on: 12 September 2003
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Variability of pro-apoptotic properties of cyclooxygenase-2 inhibitors in rheumatoid synovial fibroblasts and cancer cell lines

Authors: S Kawai, N Kusunoki and R Yamazaki

Citation: Arthritis Res Ther 2003 5(Suppl 3):38

Content type: Oral presentation Published on: 12 September 2003
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Complement, its role in innate immunity and autoimmunity

Authors: M Daha

Citation: Arthritis Res Ther 2003 5(Suppl 3):39

Content type: Oral presentation Published on: 12 September 2003
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Activation of synovial fibroblasts via Toll-like receptor signaling

Authors: D Kyburz, M Pierer, J Rethage, R Seibl, RE Gay, DA Carson and S Gay

Citation: Arthritis Res Ther 2003 5(Suppl 3):40

Content type: Oral presentation Published on: 12 September 2003
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TNF dependency of IL-17-induced joint pathology can be circumvented by Toll-like receptor-2 signaling

Authors: W Van den Berg, M Koenders, P van Lent, L Joosten and E Lubberts

Citation: Arthritis Res Ther 2003 5(Suppl 3):41

Content type: Oral presentation Published on: 12 September 2003
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Candidate targets for antibody therapy of rheumatoid arthritis: CD64 and IL-15

Authors: J van de Winkel

Citation: Arthritis Res Ther 2003 5(Suppl 3):42

Content type: Oral presentation Published on: 12 September 2003
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Mechanisms of resistance against Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts

Authors: T Pap, A Baier, I Meinecke, A Drynda, R Gay, W Neumann and S Gay

Citation: Arthritis Res Ther 2003 5(Suppl 3):43

Content type: Oral presentation Published on: 12 September 2003
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Immunologic reactants in the pathogenesis of atherosclerosis in rheumatic diseases

Authors: B Cronstein and A Reiss

Citation: Arthritis Res Ther 2003 5(Suppl 3):44

Content type: Oral presentation Published on: 12 September 2003
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Cell biology of synovial inflammation and secondary osteoporosis in rheumatoid arthritis

Authors: Y Tanaka, Y Okada, S Nakayamada, K Nakano, K Fujii and K Saito

Citation: Arthritis Res Ther 2003 5(Suppl 3):45

Content type: Oral presentation Published on: 12 September 2003
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New strategies for the in vivo regulation of metalloprotease gene expression in osteoarthritis chondrocytes by inflammatory mediators

Authors: JP Pelletier, C Boileau, D Schrier, C Flory, J Brunet, F Mineau, G Tardif, M Boily and J Martel-Pelletier

Citation: Arthritis Res Ther 2003 5(Suppl 3):46

Content type: Oral presentation Published on: 12 September 2003
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Regulation of collagenase-3 (MMP-13) gene and protein expression in human cartilage: when simple things get complicated

Authors: J Martel-Pelletier, G Tardif and JP Pelletier

Citation: Arthritis Res Ther 2003 5(Suppl 3):47

Content type: Oral presentation Published on: 12 September 2003
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TIMP-3 inhibits aggrecan breakdown in pig articular cartilage stimulated with IL-1

Authors: H Nagase, C Gendron and M Kashiwagi

Citation: Arthritis Res Ther 2003 5(Suppl 3):48

Content type: Oral presentation Published on: 12 September 2003
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3rd World Congress of the Global Arthritis Research Network (GARN): International Arthritis Summit

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