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Abatacept (CTLA4Ig) treatment increases the remission rate in rheumatoid arthritis patients refractory to methotrexate treatment

Authors: R Westhovens, P van Riel, J Sibilia, G Vratsanos, I Nuamah and JC Becker

Citation: Arthritis Res Ther 2004 6(Suppl 1):86

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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Long-term immune reconstitution in patients treated with autologous stem cell transplantation for refractory autoimmune diseases

Authors: T Alexander, G Massenkeil, GR Burmester, A Radbruch, R Arnold, F Hiepe and A Thiel

Citation: Arthritis Res Ther 2004 6(Suppl 1):84

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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Nonviral gene therapy by electrotransfer of hTNF-α soluble receptor variants: application to the treatment of collagen arthritis

Authors: C Bloquel, P Bigey, D Scherman, MC Boissier and N Bessis

Citation: Arthritis Res Ther 2004 6(Suppl 1):82

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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Suppressor of cytokine signaling (SOCS)-3 gene transfer protects against collagen-induced arthritis

Authors: FAJ van de Loo, RL Smeets, LAB Joosten and WB van den Berg

Citation: Arthritis Res Ther 2004 6(Suppl 1):80

Content type: Meeting abstract Published on: 24 February 2004

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Host immune responses to salivary gland administration of recombinant adeno-associated virus serotype 2 vectors

Authors: MR Kok, A Voutetakis, S Yamano, J Wang, A Cotrim, H Katano, I Bossis, JA Chiorini, PP Tak and BJ Baum

Citation: Arthritis Res Ther 2004 6(Suppl 1):78

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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Radiological sacroiliitis is linked with CARD15 gene polymorphisms in patients with Crohn's disease

Authors: B Vander Cruyssen, H Peeters, D Laukens, P Coucke, H Mielants, M De Vos and F De Keyser

Citation: Arthritis Res Ther 2004 6(Suppl 1):76

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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Unraveling complexity of rheumatoid synovial gene expression by comparison with purified leukocyte profiles

Authors: T Häupl, A Grützkau, J Grün, R Baumgrass, M Janitz, B Stuhlmüller, T Rohrlach, C Kaps, M Rudwaleit, L Morawietz, J Zacher, V Krenn, G-R Burmester and A Radbruch

Citation: Arthritis Res Ther 2004 6(Suppl 1):73

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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Differential regulation of mitogenic activated protein kinases by thymosin β4 sulphoxide (Tb4SO)

Authors: M Junghae, JD Young, JA Gracie and IB McInnes

Citation: Arthritis Res Ther 2004 6(Suppl 1):71

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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A customized monocyte cDNA microarray for diagnosis of rheumatoid arthritis and prognosis of anti-TNF-α therapy

Authors: B Stuhlmüller, N Tandon, C Hultschig, RJ Kuban, M Hernandez, GR Burmester and T Häupl

Citation: Arthritis Res Ther 2004 6(Suppl 1):69

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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Involvement of SUMO-1 in the regulation of apoptosis in prosthesis loosening fibroblasts

Authors: I Meinecke, A Wille, A Cinski, W Neumann, B Ink, R Hay, S Gay and T Pap

Citation: Arthritis Res Ther 2004 6(Suppl 1):67

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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Immunization with the glycolytic enzyme glucose-6-phosphate isomerase (GPI) induces peripheral polyarthritis in genetically unaltered mice

Authors: D Schubert, B Maier, L Morawietz, V Krenn and T Kamradt

Citation: Arthritis Res Ther 2004 6(Suppl 1):65

Content type: Meeting abstract Published on: 24 February 2004

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Repair of local bone erosions and reversal of systemic bone loss upon therapy with anti-TNF in combination with OPG or PTH in TNF-mediated arthritis

Authors: K Redlich, B Görtz, S Hayer, J Zwerina, N Doerr, P Kostenuik, G Kollias, G Steiner, JS Smolen and G Schett

Citation: Arthritis Res Ther 2004 6(Suppl 1):63

Content type: Meeting abstract Published on: 24 February 2004

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The active metabolite of leflunomide, A77-1726, increases proliferation of human synovial fibroblasts in presence of IL-1β

Authors: D Magne, F Mezin, G Palmer and PA Guerne

Citation: Arthritis Res Ther 2004 6(Suppl 1):61

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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TRAIL-induced rheumatoid arthritis fibroblast-like synoviocyte proliferation is inhibited by OPG

Authors: J Morel, R Audo, V Deschamps and B Combe

Citation: Arthritis Res Ther 2004 6(Suppl 1):59

Content type: Meeting abstract Published on: 24 February 2004

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Bone morphogenic protein (BMP-2) enhances expression of type II collagen and aggrecan in human chondrocytes in 3D alginate cultures

Authors: WK Aicher, B Thunemann, C Gaissmaier, J Fritz and T Gründer

Citation: Arthritis Res Ther 2004 6(Suppl 1):56

Content type: Meeting abstract Published on: 24 February 2004

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Local interferon-β gene therapy ameliorates adjuvant arthritis in rats

Authors: P Adriaansen, J Van Holten, C Kaynor, MJ Vervoordeldonk and PP Tak

Citation: Arthritis Res Ther 2004 6(Suppl 1):54

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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CD44 regulates bone erosion and osteoclastogenesis in arthritis

Authors: S Hayer, B Goertz, J Zwerina, K Redlich, O Hoffmann, M Amling, F Hilberg, G Kollias, G Steiner, EF Wagner, JS Smolen and G Schett

Citation: Arthritis Res Ther 2004 6(Suppl 1):52

Content type: Meeting abstract Published on: 24 February 2004

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Vaccination with TNF-α modulated DCs protects against CIA in an antigen-specific manner

Authors: LM van Duivenvoorde, P Louis-Plence, F Apparailly, EIH van der Voort, TJW Huizinga, C Jorgensen and REM Toes

Citation: Arthritis Res Ther 2004 6(Suppl 1):50

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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Triggering of FcGR during dendritic cell maturation leads to a decreased expression of the chemokines DC-CK1, ELC and TARC

Authors: TRDJ Radstake, R van der Voort, C Figdor, W van den Berg, P Barrera and GJ Adema

Citation: Arthritis Res Ther 2004 6(Suppl 1):48

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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Characterization of BDCA1 and BDCA4 dendritic cell subsets in rheumatoid arthritis patients

Authors: MC Lebre, SW Tas, P Reinders-Blankert, TJM Smeets and PP Tak

Citation: Arthritis Res Ther 2004 6(Suppl 1):46

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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Effect of an empty plasmid containing CpG on dendritic cells: in vitro steady state of stimulation, in vivo prevention of collagen-induced arthritis

Authors: O Jaen, MC Boissier and G Falgarone

Citation: Arthritis Res Ther 2004 6(Suppl 1):44

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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CD25brightCD4⁺ regulatory T cells accumulate in inflamed joints of patients with chronic rheumatic disease

Authors: D Cao, R van Vollenhoven, L Klareskog, C Trollmo and V Malmström

Citation: Arthritis Res Ther 2004 6(Suppl 1):42

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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Characterization of kidney infiltrating T cells in the NZB/W F1 lupus model

Authors: P Enghard, D Langnickel, GR Burmester, F Hiepe, A Radbruch and G Riemekasten

Citation: Arthritis Res Ther 2004 6(Suppl 1):41

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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T cell response in Shigella-induced reactive arthritis

Authors: H Brandt, U Stelzl, W Kuon, T Adam, KH Nierhaus and J Sieper

Citation: Arthritis Res Ther 2004 6(Suppl 1):39

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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CD28nullCD4⁺ T cells: an effector memory T cell population in patients with rheumatoid arthritis

Authors: AER Fasth, D Cao, R van Vollenhoven, C Trollmo and V Malmström

Citation: Arthritis Res Ther 2004 6(Suppl 1):37

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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HLA-DRB1 encoded predisposition to rheumatoid arthritis: the anchor hypothesis

Authors: N de Vries, H Tijssen, PLCM van Riel, LBA van de Putte and PP Tak

Citation: Arthritis Res Ther 2004 6(Suppl 1):35

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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Characterization of the T cell response to hnRNP-A2 (RA33) in HLA-DR4 transgenic mice

Authors: M Hoffmann, S Trembleau, S Hayer, JS Smolen and G Steiner

Citation: Arthritis Res Ther 2004 6(Suppl 1):33

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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IL-13 overexpression during immune complex arthritis diminishes MMP-mediated VDIPEN expression

Authors: KC Nabbe, PL van Lent, AE Holthuysen, AE Koch and WB van den Berg

Citation: Arthritis Res Ther 2004 6(Suppl 1):31

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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Human adipose tissue: an important novel source of IL-1Ra

Authors: J-M Dayer and C Meier

Citation: Arthritis Res Ther 2004 6(Suppl 1):29

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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Effects of reduced ATP-formation on cytokine production and proliferation in human peripheral CD4⁺ T cells

Authors: R Tripmacher, T Gaber, GR Burmester, A Radbruch and A Scheffold

Citation: Arthritis Res Ther 2004 6(Suppl 1):27

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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IL-20 is expressed in inflamed synovium of patients with psoriatic arthritis and rheumatoid arthritis

Authors: TJM Smeets, Y Chandrasekher, JJ Haringman and PP Tak

Citation: Arthritis Res Ther 2004 6(Suppl 1):25

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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Cytokine imbalance in NZB/W mice is associated with autoantibody levels and nephritis

Authors: P Enghard, D Langnickel, F Hiepe, GR Burmester and G Riemekasten

Citation: Arthritis Res Ther 2004 6(Suppl 1):23

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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The rheumatoid arthritis specific Sa antigen is citrullinated vimentin

Authors: ER Vossenaar, N Depres, M Lora, A van der Heijden, E Lapointe, AJW Zendman, T Senshu, WJ van Venrooij and HA Ménard

Citation: Arthritis Res Ther 2004 6(Suppl 1):21

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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Antifilaggrin antibodies in serum and synovial fluid samples of patients with rheumatoid arthritis show similar reactivity pattern towards citrulline containing peptides

Authors: M Brózik, A Magyar, R Tobi, G Bálint, ZS Balogh, A Polgár, F Hudecz and K Merétey

Citation: Arthritis Res Ther 2004 6(Suppl 1):19

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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Diagnostic performance and predictive value of serum markers for the diagnosis of rheumatoid arthritis

Authors: IEA Hoffman, I Peene, A Union, L Meheus, L De Clercq, L Schatteman, S Poriau, H Mielants, EM Veys and F De Keyser

Citation: Arthritis Res Ther 2004 6(Suppl 1):17

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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Features of the citrullinating peptidylarginine deiminase enzymes

Authors: ER Vossenaar, AJW Zendman, R Raijmakers, TJ Welting, A van der Heijden, WAM Horstman, JH Vogelzangs, S Nijenhuis, WJ van Venrooij and GJM Pruijn

Citation: Arthritis Res Ther 2004 6(Suppl 1):15

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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Immunomics in inflammatory rheumatic diseases

Authors: Z Konthur, K Adolph, G Burguera, A Sternjak, A Förster, H Lehrach, GR Burmester and K Skriner

Citation: Arthritis Res Ther 2004 6(Suppl 1):13

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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Differential regulation of the expression of chemokine receptor 3 and 4 during plasma cell differentiation

Authors: G Muehlinghaus, L Cigliano, H Leyendeckers, S Arce, A Radbruch and RA Manz

Citation: Arthritis Res Ther 2004 6(Suppl 1):11

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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Short-lived plasmablasts and long-lived plasma cells contribute to chronic humoral autoimmunity in NZB/W mice

Authors: BF Hoyer, K Moser, AE Hauser, A Peddinghaus, C Voigt, D Eilat, A Radbruch, RA Manz and F Hiepe

Citation: Arthritis Res Ther 2004 6(Suppl 1):9

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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Human cartilage glycoprotein 39-directed T cell responses in health and arthritic diseases

Authors: JHM van Bilsen, LR Lard, EIH van der Voort, D Elferink, A Bakker, H van Dongen, AMM Miltenburg, T Huizinga, R de Vries and REM Toes

Citation: Arthritis Res Ther 2004 6(Suppl 1):7

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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Antibodies against 25-mer synthetic peptide of M3 muscarinic acetylcholine receptor

Authors: P Zigon, A Hocevar, S Cucnik, B Bozic, B Rozman, M Tomsic and T Kveder

Citation: Arthritis Res Ther 2004 6(Suppl 1):5

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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Surface-bound immune complexes containing antibodies to collagen type II induce production of TNF-α, IL-1β and IL-8 from monocytes via FcγRII

Authors: M Mullazehi, L Mathsson, J Lampa and J Rönnelid

Citation: Arthritis Res Ther 2004 6(Suppl 1):2

Content type: Meeting abstract Published on: 24 February 2004

This article is part of a Supplement: Volume 6 Supplement 1
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The active metabolite of leflunomide, A77 1726, increases the production of IL-1 receptor antagonist in human synovial fibroblasts and articular chondrocytes

Leflunomide is an immunomodulatory agent used for the treatment of rheumatoid arthritis. In this study, we investigated the effect of A77 1726 – the active metabolite of leflunomide – on the production of IL-1...

Authors: Gaby Palmer, Danielle Burger, Françoise Mezin, David Magne, Cem Gabay, Jean-Michel Dayer and Pierre-André Guerne

Citation: Arthritis Res Ther 2004 6:R181

Content type: Research article Published on: 19 February 2004
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Ovariectomized rats as a model of postmenopausal osteoarthritis: validation and application

We aimed to assess the effect of ovariectomy on cartilage turnover and degradation, to evaluate whether ovariectomized (OVX) rats could form an experimental model of postmenopausal osteoarthritis. The effect o...

Authors: Pernille Høegh-Andersen, László B Tankó, Thomas L Andersen, Carina V Lundberg, John A Mo, Anne-Marie Heegaard, Jean-Marie Delaissé and Stephan Christgau

Citation: Arthritis Res Ther 2004 6:R169

Content type: Research article Published on: 19 February 2004
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The synovial proteome: analysis of fibroblast-like synoviocytes

The present studies were initiated to determine the protein expression patterns of fibroblast-like synovial (FLS) cells derived from the synovia of rheumatoid arthritis patients. The cellular proteins were sep...

Authors: Kumar Dasuri, Mihaela Antonovici, Keding Chen, Ken Wong, Kenneth Standing, Werner Ens, Hani El-Gabalawy and John A Wilkins

Citation: Arthritis Res Ther 2004 6:R161

Content type: Research article Published on: 16 February 2004
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Bystander suppression of collagen-induced arthritis in mice fed ovalbumin

We wanted to assess whether B-cell and/or T-cell responses to collagen and thereby the course of collagen-induced arthritis could be suppressed by regulatory mechanisms associated with oral tolerance to an unr...

Authors: N Fredrik Bäckström and Ulf IH Dahlgren

Citation: Arthritis Res Ther 2004 6:R151

Content type: Research article Published on: 5 February 2004
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Rheumatoid arthritis specific anti-Sa antibodies target citrullinated vimentin

Antibodies directed to the Sa antigen are highly specific for rheumatoid arthritis (RA) and can be detected in approximately 40% of RA sera. The antigen, a doublet of protein bands of about 50 kDa, is present ...

Authors: Erik R Vossenaar, Normand Després, Elvy Lapointe, Annemarie van der Heijden, Maximillian Lora, Tatsuo Senshu, Walther J van Venrooij and Henri A Ménard

Citation: Arthritis Res Ther 2004 6:R142

Content type: Research article Published on: 5 February 2004
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Measuring effectiveness of drugs in observational databanks: promises and perils

Observational databanks have inherent strengths and shortcomings. As in randomized controlled trials, poor design of these databanks can either exaggerate or reduce estimates of drug effectiveness and can limi...

Authors: Eswar Krishnan and James F Fries

Citation: Arthritis Res Ther 2004 6:41

Content type: Commentary Published on: 5 February 2004
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Flow cytometric assessment of the signaling status of human B lymphocytes from normal and autoimmune individuals

Abnormalities in lymphocyte signaling cascades are thought to play an important role in the development of autoimmune disease. However, the large amount of cellular material needed for standard biochemical ass...

Authors: Amrie C Grammer, Randy Fischer, Olivia Lee, Xuan Zhang and Peter E Lipsky

Citation: Arthritis Res Ther 2004 6:28

Content type: Review Published on: 5 February 2004
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Role of anti-cyclic citrullinated peptide antibodies in discriminating patients with rheumatoid arthritis from patients with chronic hepatitis C infection-associated polyarticular involvement

This study was performed to assess the utility of anti-cyclic citrullinated peptide (anti-CCP) antibodies in distinguishing between patients with rheumatoid arthritis (RA) and patients with polyarticular invol...

Authors: Michele Bombardieri, Cristiano Alessandri, Giancarlo Labbadia, Cristina Iannuccelli, Francesco Carlucci, Valeria Riccieri, Vincenzo Paoletti and Guido Valesini

Citation: Arthritis Res Ther 2004 6:R137

Content type: Research article Published on: 29 January 2004
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