Volume 6 Supplement 1

24th European Workshop for Rheumatology Research

Meeting abstracts

The organizer would like to thank the following companies who have generously supported the 24th European Workshop for Rheumatology Research: Abbott Immunology (Main sponsor), Amgen, Aventis, Bristol Myers Squibb, Schering Plough, Roche, MSD, Novartis, Wyeth

24th European Workshop for Rheumatology Research.

Berlin, Germany26-29 February 2004

Page 1 of 3

Differential antibody recognition of the 349–364aa B-cell epitope of human La/SSB protein and its phosphorylated analogue

Authors: AG Terzoglou, JG Routsias, HM Moutsopoulos and AG Tzioufas

Citation: Arthritis Res Ther 2004 6(Suppl 1):1

Content type: Meeting abstract Published on: 24 February 2004
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Surface-bound immune complexes containing antibodies to collagen type II induce production of TNF-α, IL-1β and IL-8 from monocytes via FcγRII

Authors: M Mullazehi, L Mathsson, J Lampa and J Rönnelid

Citation: Arthritis Res Ther 2004 6(Suppl 1):2

Content type: Meeting abstract Published on: 24 February 2004
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Prothrombin fragment F1+2 in patients with antiphospholipid antibodies

Authors: A Ambrozic, B Bozic, S Cucnik, T Kveder and B Rozman

Citation: Arthritis Res Ther 2004 6(Suppl 1):3

Content type: Meeting abstract Published on: 24 February 2004
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Concomitant appearance of anti-cardiolipin, anti-β₂-glycoprotein I, anti-prothrombin and anti-annexin V antibodies

Authors: S Cucnik, N Gaspersic, T Kveder and B Bozic

Citation: Arthritis Res Ther 2004 6(Suppl 1):4

Content type: Meeting abstract Published on: 24 February 2004
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Antibodies against 25-mer synthetic peptide of M3 muscarinic acetylcholine receptor

Authors: P Zigon, A Hocevar, S Cucnik, B Bozic, B Rozman, M Tomsic and T Kveder

Citation: Arthritis Res Ther 2004 6(Suppl 1):5

Content type: Meeting abstract Published on: 24 February 2004
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Association of anti-ribosomal P protein antibodies with neuropsychiatric systemic lupus erythematosus

Authors: A Ambrozic, B Bozic, B Rozman, B Lestan and T Kveder

Citation: Arthritis Res Ther 2004 6(Suppl 1):6

Content type: Meeting abstract Published on: 24 February 2004
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Human cartilage glycoprotein 39-directed T cell responses in health and arthritic diseases

Authors: JHM van Bilsen, LR Lard, EIH van der Voort, D Elferink, A Bakker, H van Dongen, AMM Miltenburg, T Huizinga, R de Vries and REM Toes

Citation: Arthritis Res Ther 2004 6(Suppl 1):7

Content type: Meeting abstract Published on: 24 February 2004
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Multiplex analysis of antinuclear antibodies by flow cytometry using FIDIS

Authors: PJ Charles

Citation: Arthritis Res Ther 2004 6(Suppl 1):8

Content type: Meeting abstract Published on: 24 February 2004
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Short-lived plasmablasts and long-lived plasma cells contribute to chronic humoral autoimmunity in NZB/W mice

Authors: BF Hoyer, K Moser, AE Hauser, A Peddinghaus, C Voigt, D Eilat, A Radbruch, RA Manz and F Hiepe

Citation: Arthritis Res Ther 2004 6(Suppl 1):9

Content type: Meeting abstract Published on: 24 February 2004
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Immune complexes from RA patients induce FcγRII-dependent and RF-correlated TNF-α and IL-8 production from healthy PBMC

Authors: L Mathsson, J Lampa, M Mullazehi and J Rönnelid

Citation: Arthritis Res Ther 2004 6(Suppl 1):10

Content type: Meeting abstract Published on: 24 February 2004
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Differential regulation of the expression of chemokine receptor 3 and 4 during plasma cell differentiation

Authors: G Muehlinghaus, L Cigliano, H Leyendeckers, S Arce, A Radbruch and RA Manz

Citation: Arthritis Res Ther 2004 6(Suppl 1):11

Content type: Meeting abstract Published on: 24 February 2004
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Two B cell populations differentially expressing IgVH mRNAs in human RA synovium

Authors: S Ruzickova, O Krystufkova, L Sedova, J Niederlova, Z Cimburek, T Dörner and J Vencovsky

Citation: Arthritis Res Ther 2004 6(Suppl 1):12

Content type: Meeting abstract Published on: 24 February 2004
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Immunomics in inflammatory rheumatic diseases

Authors: Z Konthur, K Adolph, G Burguera, A Sternjak, A Förster, H Lehrach, GR Burmester and K Skriner

Citation: Arthritis Res Ther 2004 6(Suppl 1):13

Content type: Meeting abstract Published on: 24 February 2004
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VIDAS-EDRA fully automated testing of autoantibodies to citrullinated proteins for the diagnosis of rheumatoid arthritis

Authors: L Nogueira, A Foussadier, C Vincent, C Clavel, N Moinard, M Jolivet and G Serre

Citation: Arthritis Res Ther 2004 6(Suppl 1):14

Content type: Meeting abstract Published on: 24 February 2004
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Features of the citrullinating peptidylarginine deiminase enzymes

Authors: ER Vossenaar, AJW Zendman, R Raijmakers, TJ Welting, A van der Heijden, WAM Horstman, JH Vogelzangs, S Nijenhuis, WJ van Venrooij and GJM Pruijn

Citation: Arthritis Res Ther 2004 6(Suppl 1):15

Content type: Meeting abstract Published on: 24 February 2004
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False positivity of rheumatoid factor and antibodies to citrullinated peptides in systemic lupus erythematosus

Authors: IEA Hoffman, I Peene, A Union, L Meheus, T Huizinga, L Cebecauer, D Isenberg, K De Bosschere, F Hulstaert, EM Veys and F De Keyser

Citation: Arthritis Res Ther 2004 6(Suppl 1):16

Content type: Meeting abstract Published on: 24 February 2004
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Diagnostic performance and predictive value of serum markers for the diagnosis of rheumatoid arthritis

Authors: IEA Hoffman, I Peene, A Union, L Meheus, L De Clercq, L Schatteman, S Poriau, H Mielants, EM Veys and F De Keyser

Citation: Arthritis Res Ther 2004 6(Suppl 1):17

Content type: Meeting abstract Published on: 24 February 2004
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Citrullinated proteins in arthritis: presence in joints and effects on immunogenicity

Authors: K Lundberg, S Nijenhuis, E Vossenaar, L Klareskog, WJ van Venrooij and H Erlandsson Harris

Citation: Arthritis Res Ther 2004 6(Suppl 1):18

Content type: Meeting abstract Published on: 24 February 2004
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Antifilaggrin antibodies in serum and synovial fluid samples of patients with rheumatoid arthritis show similar reactivity pattern towards citrulline containing peptides

Authors: M Brózik, A Magyar, R Tobi, G Bálint, ZS Balogh, A Polgár, F Hudecz and K Merétey

Citation: Arthritis Res Ther 2004 6(Suppl 1):19

Content type: Meeting abstract Published on: 24 February 2004
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The presence of deiminated fibrin in the synovial membrane is not specific for rheumatoid arthritis

Authors: S Chapuy-Regaud, M Sebbag, D Baeten, C Clavel, F De Keyser and G Serre

Citation: Arthritis Res Ther 2004 6(Suppl 1):20

Content type: Meeting abstract Published on: 24 February 2004
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The rheumatoid arthritis specific Sa antigen is citrullinated vimentin

Authors: ER Vossenaar, N Depres, M Lora, A van der Heijden, E Lapointe, AJW Zendman, T Senshu, WJ van Venrooij and HA Ménard

Citation: Arthritis Res Ther 2004 6(Suppl 1):21

Content type: Meeting abstract Published on: 24 February 2004
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Elevated expression of IL-18 in Sjögren's syndrome: distinct expression patterns of the active and proactive forms

Authors: S Boiu-Zahiu, EK Kapsogeorgou, ID Dimitriou, MP Spahidou, HM Moutsopoulos and MN Manoussakis

Citation: Arthritis Res Ther 2004 6(Suppl 1):22

Content type: Meeting abstract Published on: 24 February 2004
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Cytokine imbalance in NZB/W mice is associated with autoantibody levels and nephritis

Authors: P Enghard, D Langnickel, F Hiepe, GR Burmester and G Riemekasten

Citation: Arthritis Res Ther 2004 6(Suppl 1):23

Content type: Meeting abstract Published on: 24 February 2004
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Anti-tumour necrosis factor therapy modulates the OPG/OPGL system in rheumatoid arthritis synovium

Authors: AI Catrina, S Ernestam, E af Klint, L Klareskog and AK Ulfgren

Citation: Arthritis Res Ther 2004 6(Suppl 1):24

Content type: Meeting abstract Published on: 24 February 2004
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IL-20 is expressed in inflamed synovium of patients with psoriatic arthritis and rheumatoid arthritis

Authors: TJM Smeets, Y Chandrasekher, JJ Haringman and PP Tak

Citation: Arthritis Res Ther 2004 6(Suppl 1):25

Content type: Meeting abstract Published on: 24 February 2004
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Cross-talk between TRAIL and TGF-β in regulation of collagen production in scleroderma lung disease

Authors: VV Yurovsky

Citation: Arthritis Res Ther 2004 6(Suppl 1):26

Content type: Meeting abstract Published on: 24 February 2004
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Effects of reduced ATP-formation on cytokine production and proliferation in human peripheral CD4⁺ T cells

Authors: R Tripmacher, T Gaber, GR Burmester, A Radbruch and A Scheffold

Citation: Arthritis Res Ther 2004 6(Suppl 1):27

Content type: Meeting abstract Published on: 24 February 2004
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Intra-articular steroid treatment reduces synovial HMGB1 but not IL-1 expression in chronic arthritis

Authors: C Grundtman, E af Klint, U Andersson, L Klareskog and A Ulfgren

Citation: Arthritis Res Ther 2004 6(Suppl 1):28

Content type: Meeting abstract Published on: 24 February 2004
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Human adipose tissue: an important novel source of IL-1Ra

Authors: J-M Dayer and C Meier

Citation: Arthritis Res Ther 2004 6(Suppl 1):29

Content type: Meeting abstract Published on: 24 February 2004
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IL-1-dependent cartilage damage in a macrophage-driven arthritis model can be circumvented by T cell IL-17

Authors: MI Koenders, E Lubberts, LAB Joosten, JK Kolls and WB van den Berg

Citation: Arthritis Res Ther 2004 6(Suppl 1):30

Content type: Meeting abstract Published on: 24 February 2004
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IL-13 overexpression during immune complex arthritis diminishes MMP-mediated VDIPEN expression

Authors: KC Nabbe, PL van Lent, AE Holthuysen, AE Koch and WB van den Berg

Citation: Arthritis Res Ther 2004 6(Suppl 1):31

Content type: Meeting abstract Published on: 24 February 2004
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Overexpression of TNF causes bilateral sacroiliitis

Authors: K Redlich, B Görtz, S Hayer, J Zwerina, G Kollias, G Steiner, JS Smolen and G Schett

Citation: Arthritis Res Ther 2004 6(Suppl 1):32

Content type: Meeting abstract Published on: 24 February 2004
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Characterization of the T cell response to hnRNP-A2 (RA33) in HLA-DR4 transgenic mice

Authors: M Hoffmann, S Trembleau, S Hayer, JS Smolen and G Steiner

Citation: Arthritis Res Ther 2004 6(Suppl 1):33

Content type: Meeting abstract Published on: 24 February 2004
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Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCP) affects severity of rheumatoid arthritis

Authors: FA van Gaalen, J van Aken, TWJ Huizinga, GMTh Schreuder, FC Breedveld, E Zanelli, WJ van Venrooij, CL Verweij, RRP de Vries and REM Toes

Citation: Arthritis Res Ther 2004 6(Suppl 1):34

Content type: Meeting abstract Published on: 24 February 2004
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HLA-DRB1 encoded predisposition to rheumatoid arthritis: the anchor hypothesis

Authors: N de Vries, H Tijssen, PLCM van Riel, LBA van de Putte and PP Tak

Citation: Arthritis Res Ther 2004 6(Suppl 1):35

Content type: Meeting abstract Published on: 24 February 2004
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Influence of the physicochemical properties of the HLA-DRB1 shared epitope negative alleles on rheumatoid arthritis susceptibility

Authors: L Michou, E Petit-Teixeira, I Lemaire, C Pierlot, J Osorio, W Frigui, S Lasbleiz, P Quillet, T Bardin, B Prum and F Cornélis

Citation: Arthritis Res Ther 2004 6(Suppl 1):36

Content type: Meeting abstract Published on: 24 February 2004
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CD28nullCD4⁺ T cells: an effector memory T cell population in patients with rheumatoid arthritis

Authors: AER Fasth, D Cao, R van Vollenhoven, C Trollmo and V Malmström

Citation: Arthritis Res Ther 2004 6(Suppl 1):37

Content type: Meeting abstract Published on: 24 February 2004
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Autoreactive T cells specific for a natural intracellular hapten: an example from patients with acute myocarditis and possible consequences for other inflammatory diseases

Authors: I Melchers, G Cicek, E Schiltz, J Staiger, F-J Neumann and R Brandsch

Citation: Arthritis Res Ther 2004 6(Suppl 1):38

Content type: Meeting abstract Published on: 24 February 2004
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T cell response in Shigella-induced reactive arthritis

Authors: H Brandt, U Stelzl, W Kuon, T Adam, KH Nierhaus and J Sieper

Citation: Arthritis Res Ther 2004 6(Suppl 1):39

Content type: Meeting abstract Published on: 24 February 2004
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CD25⁺regulatory T cells can be used therapeutically in collagen-induced arthritis

Authors: ME Morgan, R Flierman, HJ Witteveen, TWJ Huizinga, RRP de Vries and REM Toes

Citation: Arthritis Res Ther 2004 6(Suppl 1):40

Content type: Meeting abstract Published on: 24 February 2004
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Characterization of kidney infiltrating T cells in the NZB/W F1 lupus model

Authors: P Enghard, D Langnickel, GR Burmester, F Hiepe, A Radbruch and G Riemekasten

Citation: Arthritis Res Ther 2004 6(Suppl 1):41

Content type: Meeting abstract Published on: 24 February 2004
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CD25brightCD4⁺ regulatory T cells accumulate in inflamed joints of patients with chronic rheumatic disease

Authors: D Cao, R van Vollenhoven, L Klareskog, C Trollmo and V Malmström

Citation: Arthritis Res Ther 2004 6(Suppl 1):42

Content type: Meeting abstract Published on: 24 February 2004
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Increased expression of chemokines DC-CK1, ELC and TARC by dendritic cells and in synovium from patients with rheumatoid arthritis

Authors: T Radstake, R van der Voort, A Sloetjes, C Figdor, W van den Berg, P Barrera and G Adema

Citation: Arthritis Res Ther 2004 6(Suppl 1):43

Content type: Meeting abstract Published on: 24 February 2004
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Effect of an empty plasmid containing CpG on dendritic cells: in vitro steady state of stimulation, in vivo prevention of collagen-induced arthritis

Authors: O Jaen, MC Boissier and G Falgarone

Citation: Arthritis Res Ther 2004 6(Suppl 1):44

Content type: Meeting abstract Published on: 24 February 2004
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RANK and RANKL expression in rheumatoid arthritis synovium and lymph nodes as markers of dendritic cell – T cell interactions

Authors: G Page and P Miossec

Citation: Arthritis Res Ther 2004 6(Suppl 1):45

Content type: Meeting abstract Published on: 24 February 2004
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Characterization of BDCA1 and BDCA4 dendritic cell subsets in rheumatoid arthritis patients

Authors: MC Lebre, SW Tas, P Reinders-Blankert, TJM Smeets and PP Tak

Citation: Arthritis Res Ther 2004 6(Suppl 1):46

Content type: Meeting abstract Published on: 24 February 2004
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Differential dendritic cell expression in chronic inflammatory arthritis: implications for their maturation, recruitment and involvement in disease

Authors: S Jongbloed, A Fraser, JA Gracie and IB McInnes

Citation: Arthritis Res Ther 2004 6(Suppl 1):47

Content type: Meeting abstract Published on: 24 February 2004
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Triggering of FcGR during dendritic cell maturation leads to a decreased expression of the chemokines DC-CK1, ELC and TARC

Authors: TRDJ Radstake, R van der Voort, C Figdor, W van den Berg, P Barrera and GJ Adema

Citation: Arthritis Res Ther 2004 6(Suppl 1):48

Content type: Meeting abstract Published on: 24 February 2004
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Phenotypic and functional deficiencies of monocyte derived dendritic cells in systemic lupus erythematosus patients

Authors: C Scheinecker, M Köller, B Zwölfer and JS Smolen

Citation: Arthritis Res Ther 2004 6(Suppl 1):49

Content type: Meeting abstract Published on: 24 February 2004
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Vaccination with TNF-α modulated DCs protects against CIA in an antigen-specific manner

Authors: LM van Duivenvoorde, P Louis-Plence, F Apparailly, EIH van der Voort, TJW Huizinga, C Jorgensen and REM Toes

Citation: Arthritis Res Ther 2004 6(Suppl 1):50

Content type: Meeting abstract Published on: 24 February 2004
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24th European Workshop for Rheumatology Research

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