Skip to main content

Articles

Page 129 of 155

  2. Symptoms originating from the central nervous system (CNS) frequently occur in patients with systemic lupus erythematosus (SLE). These symptoms are extremely diverse, including a state of dementia. The aim of ...

    Authors: Estelle Trysberg, Kina Höglund, Elisabet Svenungsson, Kaj Blennow and Andrej Tarkowski
    Citation: Arthritis Res Ther 2004 6:R129
    Content type: Research article Published on:

  3. Recent studies of the pathogenesis of rheumatoid arthritis (RA) have revealed that both synovial fibroblasts and T cells participate in the perpetuation of joint inflammation as dynamic partners in a mutual ac...

    Authors: Sue-Yun Hwang, Ju-Young Kim, Kyoung-Woon Kim, Mi-Kyung Park, Youngmee Moon, Wan-Uk Kim and Ho-Youn Kim
    Citation: Arthritis Res Ther 2004 6:R120
    Content type: Research article Published on:

  5. The objective of our study was to determine the regulatory effects that endogenous transforming growth factor β (TGFβ) exerts on T cells in the pathogenesis of collagen-induced arthritis (CIA). CIA was induced...

    Authors: Christoph Schramm, Jörg Kriegsmann, Martina Protschka, Samuel Huber, Torsten Hansen, Edgar Schmitt, Peter Robert Galle and Manfred Blessing
    Citation: Arthritis Res Ther 2004 6:R114
    Content type: Research article Published on:

  6. Tumor necrosis factor (TNF)-α is produced by cells of the immune system and is a key mediator in immune and inflammatory reactions. Through interaction with widely expressed receptors (TNF receptor 1 and TNF r...

    Authors: David J Gould, Carly Bright and Yuti Chernajovsky
    Citation: Arthritis Res Ther 2003 6:R103
    Content type: Research article Published on:

  9. Anti-Golgi complex antibodies (AGAs) are primarily associated with systemic lupus erythematosus and Sjögren's syndrome. Here we report on the immunoreactivity of AGAs against five Golgi autoantigens (giantin, ...

    Authors: Kazuhisa Nozawa, Marvin J Fritzler, Carlos A von Mühlen and Edward KL Chan
    Citation: Arthritis Res Ther 2003 6:R95
    Content type: Research article Published on:

  10. Autoimmune diseases are often characterized as clinical syndromes caused by the inappropriate activation of T or B cells resulting in systemic or organ-specific damage. However, studies support a role for the ...

    Authors: Anthony R French and Wayne M Yokoyama
    Citation: Arthritis Res Ther 2003 6:8
    Content type: Review Published on:

  11. This study was performed to investigate the relation between IgG autoantibodies against human C-reactive protein (anti-CRP) and disease activity measures in serial serum samples from 10 patients with systemic ...

    Authors: Christopher Sjöwall, Anders A Bengtsson, Gunnar Sturfelt and Thomas Skogh
    Citation: Arthritis Res Ther 2003 6:R87
    Content type: Research article Published on:

  14. The chimeric anti-CD20 monoclonal antibody rituximab has been used extensively in the treatment of B cell malignancies, and more recently it has emerged as a potential treatment for rheumatoid arthritis (RA), ...

    Authors: John D Hainsworth
    Citation: Arthritis Res Ther 2003 5(Suppl 4):S12
    Content type: Review Published on:

    This article is part of a Supplement: Volume 5 Supplement 4

  15. B lymphocytes play several critical roles in the pathogenesis of rheumatoid arthritis. They are the source of the rheumatoid factors and anticitrullinated protein antibodies, which contribute to immune complex...

    Authors: Gregg J Silverman and Dennis A Carson
    Citation: Arthritis Res Ther 2003 5(Suppl 4):S1
    Content type: Review Published on:

    This article is part of a Supplement: Volume 5 Supplement 4

  16. Antibodies directed to citrullinated proteins (anti-cyclic citrullinated peptide) are highly specific for rheumatoid arthritis (RA). Recent data suggest that the antibodies may be involved in the disease proce...

    Authors: Erik R Vossenaar, Albert JW Zendman and Walther J van Venrooij
    Citation: Arthritis Res Ther 2003 6:1
    Content type: Commentary Published on:

  19. MRL/Mp-lpr/lpr (MRL/lpr) mice spontaneously develop systemic lupus erythematosus (SLE)-like disease. The natural history of the pulmonary involvement and the underlying mechanism of leukocyte infiltration into th...

    Authors: Fumitaka Shiozawa, Tsuyoshi Kasama, Nobuyuki Yajima, Tsuyoshi Odai, Takeo Isozaki, Mizuho Matsunawa, Yoshiyuki Yoda, Masao Negishi, Hirotsugu Ide and Mitsuru Adachi
    Citation: Arthritis Res Ther 2003 6:R78
    Content type: Research article Published on:

  20. We investigated the role of the proinflammatory cytokine TNF-α, the second messenger C2-ceramide, and protein kinase R (PKR) in bovine articular cartilage degradation. Bovine articular cartilage explants were sti...

    Authors: Sophie J Gilbert, Victor C Duance and Deborah J Mason
    Citation: Arthritis Res Ther 2003 6:R46
    Content type: Research article Published on:

  21. The objective of this study was to evaluate the safety and possible efficacy of IFN-β-1a for the treatment of patients with rheumatoid arthritis (RA). Twenty-two patients with active RA were enrolled in a phas...

    Authors: Mark C Genovese, Eliza F Chakravarty, Eswar Krishnan and Larry W Moreland
    Citation: Arthritis Res Ther 2003 6:R73
    Content type: Research article Published on:

  22. The impact of diacerein, an effective cartilage targeted therapy that is used in patients with osteoarthritis, on the development and progression of chronic inflammatory arthritis was evaluated in a tumor necr...

    Authors: Eleni Douni, Petros P Sfikakis, Sylva Haralambous, Peter Fernandes and George Kollias
    Citation: Arthritis Res Ther 2003 6:R65
    Content type: Research article Published on:

  23. Inhibitors of p38 mitogen-activated protein kinase (MAPK) diminish inflammatory arthritis in experimental animals. This may be effected by diminishing the production of inflammatory mediators, but this kinase ...

    Authors: Rebecca K Studer, Rachel Bergman, Tiffany Stubbs and Kimberly Decker
    Citation: Arthritis Res Ther 2003 6:R56
    Content type: Research article Published on:

  24. Juvenile rheumatoid arthritis (JRA) has a complex, poorly characterized pathophysiology. Modeling of transcriptosome behavior in pathologic specimens using microarrays allows molecular dissection of complex au...

    Authors: James N Jarvis, Igor Dozmorov, Kaiyu Jiang, Mark Barton Frank, Peter Szodoray, Philip Alex and Michael Centola
    Citation: Arthritis Res Ther 2003 6:R15
    Content type: Research article Published on:

  26. The presence of anti-α-fodrin autoantibodies has been reported to be a highly specific and sensitive test for the diagnosis of Sjögren's syndrome (SjS). We looked (in Nijmegen) for anti-α-fodrin, anti-Ro60, an...

    Authors: Michiel M Zandbelt, Judith Vogelzangs, Leo BA van de Putte, Walther J van Venrooij and Frank HJ van den Hoogen
    Citation: Arthritis Res Ther 2003 6:R33
    Content type: Research article Published on:

  27. Endogenous opioid peptides have an essential role in the intrinsic modulation and control of inflammatory pain, which could be therapeutically useful. In this study, we established a muscular electroporation m...

    Authors: I-Chuan Chuang, Chien-Ming Jhao, Chih-Hsun Yang, Hsien-Chang Chang, Chien-Wen Wang, Cheng-Yuan Lu, Yao-Jen Chang, Sheng-Han Lin, Pao-Lin Huang and Lin-Cheng Yang
    Citation: Arthritis Res Ther 2003 6:R7
    Content type: Research article Published on:

  28. It is widely accepted that cell-mediated immune functions decline with age, rendering an individual more susceptible to infection and possibly cancer, as well as to age-associated autoimmune diseases. The exac...

    Authors: Tamàs Fülöp Jr, Anis Larbi, Gilles Dupuis and Graham Pawelec
    Citation: Arthritis Res Ther 2003 5:290
    Content type: Review Published on:

  30. Recent advances in the study of global patterns of gene expression with the use of microarray technology, coupled with data analysis using sophisticated statistical algorithms, have provided new insights into ...

    Authors: Mary K Crow and Jay Wohlgemuth
    Citation: Arthritis Res Ther 2003 5:279
    Content type: Review Published on:

  31. Children with rheumatic oligoarthritis and polyarthritis frequently establish persistent parvovirus B19 infections that may be associated with the production of antiphospholipid antibodies (anti-PL IgG). In th...

    Authors: Hartwig W Lehmann, Annelie Plentz, Philipp von Landenberg, Esther Müller-Godeffroy and Susanne Modrow
    Citation: Arthritis Res Ther 2003 6:R1
    Content type: Research article Published on:

  32. Synovial biomarker analysis in rheumatoid arthritis can be used to evaluate drug effect in clinical trials of novel therapeutic agents. Previous studies of synovial gene expression for these studies have mainl...

    Authors: David L Boyle, Sanna Rosengren, William Bugbee, Arthur Kavanaugh and Gary S Firestein
    Citation: Arthritis Res Ther 2003 5:R352
    Content type: Research article Published on:

  33. Arthritis susceptibility genes were sought by analysis of differential gene expression between pristane-induced arthritis (PIA)-susceptible DA rats and PIA-resistant E3 rats. Inguinal lymph nodes of naïve anim...

    Authors: Lena Wester, Dirk Koczan, Jens Holmberg, Peter Olofsson, Hans-Jürgen Thiesen, Rikard Holmdahl and Saleh Ibrahim
    Citation: Arthritis Res Ther 2003 5:R361
    Content type: Research article Published on:

  34. Synovial tissue is readily accessible by closed needle or arthroscopic biopsy. These techniques provide adequate tissue for most diagnostic requirements. Examination of synovial tissue can assist in the diagno...

    Authors: Barry Bresnihan
    Citation: Arthritis Res Ther 2003 5:271
    Content type: Review Published on:

  35. The CD20 cell marker appears early in the process of B cell development. In this review we focus on the results of attempts to utilize B cell depletion based on the use of a chimeric monoclonal antibody (MAb) ...

    Authors: Claire Gorman, Maria Leandro and David Isenberg
    Citation: Arthritis Res Ther 2003 5(Suppl 4):S17
    Content type: Review Published on:

    This article is part of a Supplement: Volume 5 Supplement 4

  36. The role of B cells in rheumatoid arthritis (RA) has been debated for decades. However, recent clinical trial data indicating that depletion of B cells in RA patients is of therapeutic benefit has validated th...

    Authors: Thomas J Oligino and Stacie A Dalrymple
    Citation: Arthritis Res Ther 2003 5(Suppl 4):S7
    Content type: Review Published on:

    This article is part of a Supplement: Volume 5 Supplement 4

  37. Etanercept can be used both as monotherapy and in combination with methotrexate (MTX), but direct comparisons of these two options have not yet been reported. In order to compare the results seen in actual pra...

    Authors: Ronald F van Vollenhoven, Sofia Ernestam, Anders Harju, Johan Bratt and Lars Klareskog
    Citation: Arthritis Res Ther 2003 5:R347
    Content type: Research article Published on:

  39. Inflammation and inflammatory responses are modulated by a bidirectional communication between the neuroendocrine and immune system. Many lines of research have established the numerous routes by which the imm...

    Authors: Farideh Eskandari, Jeanette I Webster and Esther M Sternberg
    Citation: Arthritis Res Ther 2003 5:251
    Content type: Review Published on:
  • Logo
Submit manuscript

Follow

Annual Journal Metrics

  • Citation Impact 2023
    Journal Impact Factor: 4.4
    5-year Journal Impact Factor: 4.9
    Source Normalized Impact per Paper (SNIP): 1.294
    SCImago Journal Rank (SJR): 1.518

    Speed 2023
    Submission to first editorial decision (median days): 9
    Submission to acceptance (median days): 111

    Usage 2023
    Downloads: 3,331,819
    Altmetric mentions: 1,885

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us