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  23. Authors: I Kötter, M Treusch, R Vonthein, M Zierhut, A Eckstein, T Ness, I Günaydin, B Grimbacher, S Blaschke, HH Peter and N Stübiger
    Citation: Arthritis Res Ther 2003 5(Suppl 2):5
    Content type: Meeting abstract Published on:

    This article is part of a Supplement: Volume 5 Supplement 2

  28. Genetic control of immune reactions has a major role in the development of rheumatic heart disease (RHD) and differs between patients with rheumatic fever (RF). Some authors think the risk of acquiring RHD is ...

    Authors: Valda Stanevicha, Jelena Eglite, Arturs Sochnevs, Dace Gardovska, Dace Zavadska and Ruta Shantere
    Citation: Arthritis Res Ther 2003 5:R340
    Content type: Research article Published on:

  29. Fragments of fibronectin (FN) corresponding to the N-terminal heparin-binding domain have been observed to promote catabolic chondrocytic gene expression and chondrolysis. We therefore characterized FN species...

    Authors: John H Peters, Steven Carsons, Mika Yoshida, Fred Ko, Skye McDougall, Grace A Loredo and Theodore J Hahn
    Citation: Arthritis Res Ther 2003 5:R329
    Content type: Research article Published on:

  30. Vasoactive intestinal peptide (VIP) is an anti-inflammatory immunomodulatory neuropeptide with therapeutic potential demonstrated for collagen-induced arthritis. The aim of this study was to characterise its p...

    Authors: Andrew D Foey, Sarah Field, Salman Ahmed, Abhilash Jain, Marc Feldmann, Fionula M Brennan and Richard Williams
    Citation: Arthritis Res Ther 2003 5:R317
    Content type: Research article Published on:

  32. Bone erosion is a hallmark of rheumatoid arthritis. Recent evidence from experimental arthritis suggests that osteoclasts are essential for the formation of local bone erosions. Two essential regulators of ost...

    Authors: Georg Schett, Kurt Redlich and Josef S Smolen
    Citation: Arthritis Res Ther 2003 5:239
    Content type: Review Published on:

  33. Damage to cartilage is of great clinical consequence given the tissue's limited intrinsic potential for healing. Current treatments for cartilage repair are less than satisfactory, and rarely restore full func...

    Authors: Richard Tuli, Wan-Ju Li and Rocky S Tuan
    Citation: Arthritis Res Ther 2003 5:235
    Content type: Commentary Published on:

  34. Rheumatoid arthritis (RA), like many other autoimmune syndromes, is a disease of adults, with the highest incidence rates reported in the elderly. The immune system undergoes profound changes with advancing ag...

    Authors: Jörg J Goronzy and Cornelia M Weyand
    Citation: Arthritis Res Ther 2003 5:225
    Content type: Review Published on:

  36. During inflammatory processes, monocytes leave the blood stream at increased rates and enter inflammation tissue, where they undergo phenotypic transformation to mature macrophages with enhanced phagocytic act...

    Authors: Sharon D Luikart, Hollis E Krug, Robert D Nelson, Timothy Hinkel, Peter Majeski, Pankaj Gupta, Maren L Mahowald and Theodore Oegema
    Citation: Arthritis Res Ther 2003 5:R310
    Content type: Research article Published on:

  37. Osteoporosis results from a loss of bone mass and bone structure such that the bone becomes weak and fractures with very little trauma. Until recently, the approved osteoporosis therapies prevented more bone l...

    Authors: Nancy E Lane and Ariella Kelman
    Citation: Arthritis Res Ther 2003 5:214
    Content type: Review Published on:

  38. Anakinra, the recombinant form of IL-1 receptor antagonist (IL-1Ra), has been approved for clinical use in the treatment of rheumatoid arthritis as the drug Kineretâ„¢, but it must be administered daily by subcu...

    Authors: Jean-Noel Gouze, Elvire Gouze, Glyn D Palmer, Victor S Liew, Arnulf Pascher, Oliver B Betz, Thomas S Thornhill, Christopher H Evans, Alan J Grodzinsky and Steven C Ghivizzani
    Citation: Arthritis Res Ther 2003 5:R301
    Content type: Research article Published on:

  40. Circulating CD3+CD4+CD28- cells exhibit reduced apoptosis and were found to be more enriched in patients with ankylosing spondylitis than in age-matched healthy control individuals (7.40 ± 6.6% versus 1.03 ± 1.0%...

    Authors: Christina Duftner, Christian Goldberger, Albrecht Falkenbach, Reinhard Würzner, Barbara Falkensammer, Karl P Pfeiffer, Elisabeth Maerker-Hermann and Michael Schirmer
    Citation: Arthritis Res Ther 2003 5:R292
    Content type: Research article Published on:

  42. A synthetic triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid (CDDO), has been reported to have anti-inflammatory properties and to decrease the interleukin-1 (IL-1)-induced expression of matrix metal...

    Authors: Sarah Elliott, Ezra Hays, Michael Mayor, Michael Sporn and Matthew Vincenti
    Citation: Arthritis Res Ther 2003 5:R285
    Content type: Research article Published on:

  43. The aim of this research was to determine whether all memory T cells have the same propensity to migrate to the joint in patients with juvenile idiopathic arthritis. Paired synovial fluid and peripheral blood ...

    Authors: Antony PB Black, Hansha Bhayani, Clive AJ Ryder, Mark T Pugh, Janet MM Gardner-Medwin and Taunton R Southwood
    Citation: Arthritis Res Ther 2003 5:R277
    Content type: Research article Published on:

  44. An impaired differentiation of naive CD4+ T cells towards Th2 cells may contribute to the chronic tissue-destructive T-cell activity in rheumatoid arthritis (RA). The differentiation of naive CD4+ T cells into me...

    Authors: Joël AG van Roon, Catharina AFM Glaudemans, Johannes WJ Bijlsma and Floris PJG Lafeber
    Citation: Arthritis Res Ther 2003 5:R269
    Content type: Research article Published on:

  45. Behçet's disease is a multisystem disease in which there is evidence of immunological dysregulation. It has been proposed that γ/δ T cells are involved in its pathogenesis. The aim of the present study was to ...

    Authors: Giovanni Triolo, Antonina Accardo-Palumbo, Francesco Dieli, Francesco Ciccia, Angelo Ferrante, Ennio Giardina, Caterina Di Sano and Giuseppe Licata
    Citation: Arthritis Res Ther 2003 5:R262
    Content type: Research article Published on:

  46. The aim of the present study was to investigate the expression of Fas in periarticular tenocytes of patients with osteoarthritis (OA) and to study their susceptibility to Fas ligand-mediated apoptosis. Tendon ...

    Authors: Andreas Machner, Anja Baier, Aline Wille, Susanne Drynda, Géza Pap, Andreas Drynda, Christian Mawrin, Frank Bühling, Steffen Gay, Wolfram Neumann and Thomas Pap
    Citation: Arthritis Res Ther 2003 5:R253
    Content type: Research article Published on:

  47. To improve our knowledge on the pathophysiology of rheumatoid arthritis (RA), we investigated gene expression patterns in synovial tissue from RA and osteoarthritis (OA) patients. DNA oligonucleotide microarra...

    Authors: Peter Ruschpler, Peter Lorenz, Wolfram Eichler, Dirk Koczan, Claudia Hänel, Roger Scholz, Christian Melzer, Hans-Jürgen Thiesen and Peter Stiehl
    Citation: Arthritis Res Ther 2003 5:R241
    Content type: Research article Published on:

  49. We investigated whether plasma and synovial fluid (SF) samples from patients with rheumatoid arthritis (RA) contained extracellular mitochondrial DNA (mtDNA) or the oxidatively damaged DNA adduct 8-hydroxy-2'-...

    Authors: Shahin Hajizadeh, Jeroen DeGroot, Johan M TeKoppele, Andrej Tarkowski and L Vincent Collins
    Citation: Arthritis Res Ther 2003 5:R234
    Content type: Research article Published on:
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Arthritis Research & Therapy

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