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  1. Obesity is associated with the development and progression of osteoarthritis (OA). Although the infrapatellar fat pad (IFP) could be involved in this association, due to its intracapsular localization in the k...

    Authors: Anja J. de Jong, Inge R. Klein-Wieringa, Stefan N. Andersen, Joanneke C. Kwekkeboom, Linda Herb-van Toorn, Badelog J. E. de Lange-Brokaar, Danny van Delft, John Garcia, Wu Wei, Huub J. L. van der Heide, Yvonne M. Bastiaansen-Jenniskens, Gerjo J. V. M. van Osch, Annemarie M. Zuurmond, Vedrana Stojanovic-Susulic, Rob G. H. H. Nelissen, René E. M. Toes…
    Citation: Arthritis Research & Therapy 2017 19:186
  2. Currently, although several categories of biological disease-modifying antirheumatic drugs (bDMARDs) are available, there are few data informing selection of initial treatment for individual patients with rheu...

    Authors: Jin Nakagawa, Yoshinobu Koyama, Atsushi Kawakami, Yukitaka Ueki, Hiroshi Tsukamoto, Takahiko Horiuchi, Shuji Nagano, Ayumi Uchino, Toshiyuki Ota, Mitsuteru Akahoshi and Koichi Akashi
    Citation: Arthritis Research & Therapy 2017 19:185
  3. The first prospective population-based study to examine risk of erectile dysfunction in men with gout in the western world has been published. It reports that following their first diagnosis of gout, men have ...

    Authors: Abhishek Abhishek and Michael Doherty
    Citation: Arthritis Research & Therapy 2017 19:184

    The original article was published in Arthritis Research & Therapy 2017 19:123

  4. Overexpression of membranous CD154 in T lymphocytes has been found previously in systemic lupus erythematosus (SLE). Because hydroxychloroquine (HCQ) has been used frequently in the treatment of lupus, we soug...

    Authors: Shu-Fen Wu, Chia-Bin Chang, Jui-Mei Hsu, Ming-Chi Lu, Ning-Sheng Lai, Chin Li and Chien-Hsueh Tung
    Citation: Arthritis Research & Therapy 2017 19:183
  5. Methotrexate (MTX) is the standard first-line therapy in rheumatoid arthritis (RA) with variable clinical efficacy that is difficult to predict. The glycosylation status of immunoglobulin G (IgG) is altered in...

    Authors: Susanna L. Lundström, Aase H. Hensvold, Dorothea Rutishauser, Lars Klareskog, A. Jimmy Ytterberg, Roman A. Zubarev and Anca I. Catrina
    Citation: Arthritis Research & Therapy 2017 19:182
  6. Few clinical trials have investigated the safety and efficacy of mesenchymal stem cells for the management of post-traumatic osteoarthritis. The objectives of this pilot study were to determine the safety and ...

    Authors: Yuanyuan Wang, Andrew Shimmin, Peter Ghosh, Paul Marks, James Linklater, David Connell, Stephen Hall, Donna Skerrett, Silviu Itescu and Flavia M. Cicuttini
    Citation: Arthritis Research & Therapy 2017 19:180
  7. Lysyl oxidase like-2 (LOXL2) is a copper-dependent amine oxidase. Our previous studies showed that LOXL2 is elevated during mouse fracture healing. The goal of this study was to evaluate the potential of LOXL2...

    Authors: Weam Alshenibr, Mustafa M. Tashkandi, Saqer F. Alsaqer, Yazeed Alkheriji, Amelia Wise, Sadanand Fulzele, Pushkar Mehra, Mary B. Goldring, Louis C. Gerstenfeld and Manish V. Bais
    Citation: Arthritis Research & Therapy 2017 19:179
  8. Primary Sjögren’s syndrome (pSS) is a common chronic autoimmune disease characterized by lymphocytic infiltration of exocrine glands and peripheral lymphocyte perturbation. In the current study, we aimed to in...

    Authors: Cristiano Alessandri, Francesco Ciccia, Roberta Priori, Elisa Astorri, Giuliana Guggino, Riccardo Alessandro, Aroldo Rizzo, Fabrizio Conti, Antonina Minniti, Cristiana Barbati, Marta Vomero, Monica Pendolino, Annacarla Finucci, Elena Ortona, Tania Colasanti, Marina Pierdominici…
    Citation: Arthritis Research & Therapy 2017 19:178
  9. Ankylosing spondylitis (AS) is a chronic rheumatic and autoimmune disease. Little is known about the potential role of DNA methylation in the pathogenesis of AS. This study was undertaken to explore the potent...

    Authors: Jingcan Hao, Yang Liu, Jiawen Xu, Wenyu Wang, Yan Wen, Awen He, Qianrui Fan, Xiong Guo and Feng Zhang
    Citation: Arthritis Research & Therapy 2017 19:177

    The Correction to this article has been published in Arthritis Research & Therapy 2022 24:182

  10. A novel anti-mouse CD3ε antibody, Dow2, recognizes mouse CD3ε without activating T cells and suppresses T-cell activation. The purpose of this study was to determine whether Dow2 can inhibit T cells in uveitis.

    Authors: Sunao Sugita, Jun Shimizu, Kenichi Makabe, Hiroshi Keino, Takeshi Watanabe and Masayo Takahashi
    Citation: Arthritis Research & Therapy 2017 19:176
  11. The study was performed to evaluate whether targeted alpha-2-macroglobulin (A2M) variants have a similar or enhanced function at wild-type (wt)-A2M to attenuate cartilage degeneration in vivo.

    Authors: Yang Zhang, Xiaochun Wei, Shawn Browning, Gaetano Scuderi, Lewis S. Hanna and Lei Wei
    Citation: Arthritis Research & Therapy 2017 19:175
  12. Dermatomyositis (DM) is inflammatory myopathy or myositis characterized by muscle weakness and skin manifestations. In the differential diagnosis of DM the evaluation of the muscle biopsy is of importance amon...

    Authors: Xavier Suárez-Calvet, Eduard Gallardo, Iago Pinal-Fernandez, Noemi De Luna, Cinta Lleixà, Jordi Díaz-Manera, Ricardo Rojas-García, Ivan Castellví, M. Angeles Martínez, Josep M. Grau, Albert Selva-O’Callaghan and Isabel Illa
    Citation: Arthritis Research & Therapy 2017 19:174
  13. Nephrolithiasis (NL) is known to be associated with gout, although there are few comparative studies on risk and risk factors for NL in gout compared to population cohorts. In this cohort study we investigated...

    Authors: A. J. Landgren, L. T. H. Jacobsson, U. Lindström, T. Z. S. Sandström, P. Drivelegka, L. Björkman, E. Fjellstedt and M. Dehlin
    Citation: Arthritis Research & Therapy 2017 19:173
  14. Ultrasonography (US) and dual-energy computed tomography (DECT) can assess urate burden in gout. The objective of this study was to compare the quantification of urate deposition provided by US to the one prov...

    Authors: Tristan Pascart, Agathe Grandjean, Laurène Norberciak, Vincent Ducoulombier, Marguerite Motte, Hélène Luraschi, Marie Vandecandelaere, Catherine Godart, Eric Houvenagel, Nasser Namane and Jean-François Budzik
    Citation: Arthritis Research & Therapy 2017 19:171
  15. Methotrexate is endorsed to be used as first-line treatment in rheumatoid arthritis (RA). However, a large proportion of patients need additional treatment with a biological disease-modifying anti-rheumatic dr...

    Authors: Xavier M. Teitsma, Johannes W. G. Jacobs, Michal Mokry, Michelle E. A. Borm, Attila Pethö-Schramm, Jacob M. van Laar, Johannes W. J. Bijlsma and Floris P. J. Lafeber
    Citation: Arthritis Research & Therapy 2017 19:170
  16. There is an obvious need to identify biomarkers that could predict patient response to an osteoarthritis (OA) treatment. This post hoc study explored in a 2-year randomized controlled trial in patients with kn...

    Authors: Johanne Martel-Pelletier, Jean-Pierre Raynauld, François Mineau, François Abram, Patrice Paiement, Philippe Delorme and Jean-Pierre Pelletier
    Citation: Arthritis Research & Therapy 2017 19:169
  17. This study aimed to compare efficacy and safety of test-adalimumab (CinnoRA®, CinnaGen, Iran) to the innovator product (Humira®, AbbVie, USA) in adult patients with active rheumatoid arthritis (RA).

    Authors: Ahmadreza Jamshidi, Farhad Gharibdoost, Mahdi Vojdanian, Soosan G. Soroosh, Mohsen Soroush, Arman Ahmadzadeh, Mohammad Ali Nazarinia, Mohammad Mousavi, Hadi Karimzadeh, Mohammad Reza Shakibi, Zahra Rezaieyazdi, Maryam Sahebari, Asghar Hajiabbasi, Ali Asghar Ebrahimi, Najmeh Mahjourian and Amin Mohammadinejad Rashti
    Citation: Arthritis Research & Therapy 2017 19:168
  18. Ultrasound is used increasingly for diagnosing large vessel vasculitis (LVV). The application of Doppler in LVV is very different from in arthritic conditions. This paper aims to explain the most important Dop...

    Authors: L. Terslev, A. P. Diamantopoulos, U. Møller Døhn, W. A. Schmidt and S. Torp-Pedersen
    Citation: Arthritis Research & Therapy 2017 19:167
  19. Rheumatoid arthritis (RA) is a common autoimmune disease characterized by chronic inflammation of the joints, leading to bone erosion and joint dysfunction. Despite the recent successes of disease-modifying an...

    Authors: Susan MacLauchlan, Maria A. Zuriaga, José J. Fuster, Carla M. Cuda, Jennifer Jonason, Fernanda Behzadi, Jennifer Parker Duffen, G. Kenneth Haines III, Tamar Aprahamian, Harris Perlman and Kenneth Walsh
    Citation: Arthritis Research & Therapy 2017 19:166
  20. Systemic sclerosis (SSc) is an autoimmune disease involving the skin and several internal organs. Most therapies available for this disease are symptomatic. Given the difficulty in treating SSc, we conducted t...

    Authors: Huayong Zhang, Jun Liang, Xiaojun Tang, Dandan Wang, Xuebing Feng, Fan Wang, Bingzhu Hua, Hong Wang and Lingyun Sun
    Citation: Arthritis Research & Therapy 2017 19:165
  21. Few studies have investigated the impact of obesity on the response to tumor necrosis factor inhibitors (TNFi) in patients with axial spondyloarthritis (axSpA). The aim of our study was to investigate the impa...

    Authors: Raphael Micheroli, Monika Hebeisen, Lukas M. Wildi, Pascale Exer, Giorgio Tamborrini, Jürg Bernhard, Burkhard Möller, Pascal Zufferey, Michael J. Nissen, Almut Scherer and Adrian Ciurea
    Citation: Arthritis Research & Therapy 2017 19:164
  22. Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by uncontrolled joint inflammation and destruction of bone and cartilage. We previously reported that C-X-C motif chemokine 10 (CXCL10; a...

    Authors: Jong-Ho Lee, Bongjun Kim, Won Jong Jin, Hong-Hee Kim, Hyunil Ha and Zang Hee Lee
    Citation: Arthritis Research & Therapy 2017 19:163
  23. Systemic sclerosis is considered a disease dominated by a “loss of angiogenesis”, although in its early phases evidence indicates a disturbed angiogenic response only. In fact, microvascular changes are primar...

    Authors: Marco Matucci-Cerinic, Mirko Manetti, Cosimo Bruni, Ines Chora, Silvia Bellando-Randone, Gemma Lepri, Amato De Paulis and Serena Guiducci
    Citation: Arthritis Research & Therapy 2017 19:162
  24. Some gout-associated loci interact with dietary exposures to influence outcome. The aim of this study was to systematically investigate interactions between alcohol exposure and urate-associated loci in gout.

    Authors: Humaira Rasheed, Lisa K. Stamp, Nicola Dalbeth and Tony R. Merriman
    Citation: Arthritis Research & Therapy 2017 19:161
  25. The Fc glycosylation of immunoglobulin G (IgG) is well known to associate with rheumatoid arthritis (RA) disease activity. The same may be true for other classes of Igs. In the present study, we sought to dete...

    Authors: Albert Bondt, Simone Nicolardi, Bas C. Jansen, T. Martijn Kuijper, Johanna M. W. Hazes, Yuri E. M. van der Burgt, Manfred Wuhrer and Radboud J. E. M. Dolhain
    Citation: Arthritis Research & Therapy 2017 19:160
  26. Biologic disease-modifying antirheumatic drugs (DMARDs) are increasingly used for rheumatoid arthritis (RA) treatment. However, little is known based on contemporary data about the factors associated with DMAR...

    Authors: Yinzhu Jin, Rishi J. Desai, Jun Liu, Nam-Kyong Choi and Seoyoung C. Kim
    Citation: Arthritis Research & Therapy 2017 19:159
  27. The aim was to study changes in immunohistochemical expression markers of synovial and skin inflammation, clinical outcomes and magnetic resonance imaging (MRI) scores with abatacept treatment in patients with...

    Authors: Agnes Szentpetery, Eric Heffernan, Martina Gogarty, Lisa Mellerick, Janet McCormack, Muhammad Haroon, Musaab Elmamoun, Phil Gallagher, Genevieve Kelly, Aurelie Fabre, Brian Kirby and Oliver FitzGerald
    Citation: Arthritis Research & Therapy 2017 19:158
  28. A hallmark of osteoarthritis is increased proteolytic cleavage of aggrecan. Cross talk between cartilage and the synovium + joint capsule (SJC) can drive cartilage degradation by activating proteases in both t...

    Authors: Per Swärd, Yang Wang, Maria Hansson, L. Stefan Lohmander, Alan J. Grodzinsky and André Struglics
    Citation: Arthritis Research & Therapy 2017 19:157
  29. Systemic sclerosis (SSc; scleroderma) is an uncommon autoimmune rheumatic disease characterised by autoimmunity, vasculopathy and fibrosis. Gene expression profiling distinguishes scleroderma from normal skin,...

    Authors: Emma C. Derrett-Smith, Viktor Martyanov, Cecilia B. Chighizola, Pia Moinzadeh, Corrado Campochiaro, Korsa Khan, Tammara A. Wood, Pier Luigi Meroni, David J. Abraham, Voon H. Ong, Robert Lafyatis, Michael L. Whitfield and Christopher P. Denton
    Citation: Arthritis Research & Therapy 2017 19:156
  30. Stringent remission criteria are crucial in rheumatoid arthritis (RA) assessment. Disease activity score in 28 joints (DAS28)-remission has not been included among American College of Rheumatology/European Lea...

    Authors: M. Schoels, F. Alasti, J. S. Smolen and D. Aletaha
    Citation: Arthritis Research & Therapy 2017 19:155
  31. Histone deacetylase (HDAC) inhibitor has recently been reported to have a therapeutic effect as an anti-inflammatory agent in collagen-induced arthritis (CIA). We investigated the therapeutic effect of a new s...

    Authors: Bo Ram Oh, Dong-hyeon Suh, Daekwon Bae, Nina Ha, Young Il Choi, Hyun Jung Yoo, Jin Kyun Park, Eun Young Lee, Eun Bong Lee and Yeong Wook Song
    Citation: Arthritis Research & Therapy 2017 19:154
  32. Patients with inflammatory joint diseases (IJD) have increased risk of cardiovascular disease (CVD). Our aim was to compare CVD risk profiles in patients with IJD, including rheumatoid arthritis (RA), axial sp...

    Authors: Grunde Wibetoe, Eirik Ikdahl, Silvia Rollefstad, Inge C. Olsen, Kjetil Bergsmark, Tore K. Kvien, Anne Salberg, Dag Magnar Soldal, Gunnstein Bakland, Åse Lexberg, Bjørg-Tilde Fevang, Hans Christian Gulseth, Glenn Haugeberg and Anne Grete Semb
    Citation: Arthritis Research & Therapy 2017 19:153
  33. Authors: Santos Castañeda, Irene Llorente, Rosario García-Vicuña and Isidoro González-Álvaro
    Citation: Arthritis Research & Therapy 2017 19:152
  34. Osteoarthritis (OA) is a complex disease, which affects multiple tissues, namely the subchondral bone, articular cartilage and synovial membrane. Alterations of the subchondral bone include an increased, yet u...

    Authors: Élie Abed, Aline Delalandre and Daniel Lajeunesse
    Citation: Arthritis Research & Therapy 2017 19:151
  35. Autologous chondrocyte implantation (ACI) can be used in the treatment of focal cartilage injuries to prevent the onset of osteoarthritis (OA). However, we are yet to understand fully why some individuals do n...

    Authors: Charlotte H. Hulme, Emma L. Wilson, Mandy J. Peffers, Sally Roberts, Deborah M. Simpson, James B. Richardson, Pete Gallacher and Karina T. Wright
    Citation: Arthritis Research & Therapy 2017 19:150
  36. The World Health Organization (WHO) has ranked musculoskeletal diseases among the top ten leading causes of disability in the Middle East. The situation in the Middle East is unique as, although seventeen coun...

    Authors: Abdulla Watad, Jamal Al-Saleh, Merav Lidar, Howard Amital and Yehuda Shoenfeld
    Citation: Arthritis Research & Therapy 2017 19:149
  37. Patients with rheumatoid arthritis (RA) are at increased risk of developing cardiovascular disease (CVD). Our aim was to evaluate the impact of factors related to CVD, such as smoking, lipid levels, hypertensi...

    Authors: Heidi Kokkonen, Hans Stenlund and Solbritt Rantapää-Dahlqvist
    Citation: Arthritis Research & Therapy 2017 19:148
  38. Valid detection of inflamed joints is essential for correct classification, therapeutic decisions, prognosis and assessment of treatment efficacy in juvenile idiopathic arthritis (JIA). Fluorescence optical im...

    Authors: Ariane Klein, Georg Werner Just, Stephanie Gabriele Werner, Prasad T. Oommen, Kirsten Minden, Ingrid Becker, Hans-Eckhard Langer, Dirk Klee and Gerd Horneff
    Citation: Arthritis Research & Therapy 2017 19:147
  39. Severe chronic pain is one of the hallmarks and most debilitating manifestations of inflammatory arthritis. It represents a significant problem in the clinical management of patients with common chronic inflam...

    Authors: Bradford D. Fischer, Adeshina Adeyemo, Michael E. O’Leary and Andrea Bottaro
    Citation: Arthritis Research & Therapy 2017 19:146
  40. Prokinetics are used to treat enteric dismotility symptoms in systemic sclerosis (SSc) patients, but they often lack adequate efficacy. The most effective prokinetics belonging to the serotonin (5-HT4) receptor a...

    Authors: Barbara Vigone, Monica Caronni, Adriana Severino, Chiara Bellocchi, Anna Rita Baldassarri, Mirella Fraquelli, Gaia Montanelli, Alessandro Santaniello and Lorenzo Beretta
    Citation: Arthritis Research & Therapy 2017 19:145
  41. Despite the important role that microRNAs (miRNAs) play in immunity and inflammation, their involvement in systemic sclerosis (SSc) remains poorly characterized. miRNA-155 (miR-155) plays a role in pulmonary f...

    Authors: Carol M. Artlett, Sihem Sassi-Gaha, Jennifer L. Hope, Carol A. Feghali-Bostwick and Peter D. Katsikis
    Citation: Arthritis Research & Therapy 2017 19:144
  42. To understand the impact of yet undiagnosed non-radiographic axial spondyloarthritis (nr-axSpA) and ankylosing spondylitis (AS) on work outcomes in a cohort of patients with long-lasting chronic low back pain ...

    Authors: Lonneke van Hoeven, Annelies E. R. C. H. Boonen, Johanna M. W. Hazes and Angelique E. A. M. Weel
    Citation: Arthritis Research & Therapy 2017 19:143
  43. The peripheral blood (PB) monocyte pool contains osteoclast progenitors (OCPs), which contribute to osteoresorption in inflammatory arthritides and are influenced by the cytokine and chemokine milieu. We aimed...

    Authors: Alan Sucur, Zrinka Jajic, Marinko Artukovic, Marina Ikic Matijasevic, Branimir Anic, Darja Flegar, Antonio Markotic, Tomislav Kelava, Sanja Ivcevic, Natasa Kovacic, Vedran Katavic and Danka Grcevic
    Citation: Arthritis Research & Therapy 2017 19:142
  44. To analyze differences in the recognition of anti-citrullinated peptide/protein antibody (ACPA) citrullinated epitopes and isotypes in patients with palindromic rheumatism (PR) and rheumatoid arthritis (RA).

    Authors: Sonia Cabrera-Villalba, María José Gomara, Juan D. Cañete, Julio Ramírez, Georgina Salvador, Virginia Ruiz-Esquide, Maria Victoria Hernández, José Inciarte-Mundo, Isabel Haro and Raimon Sanmartí
    Citation: Arthritis Research & Therapy 2017 19:141
  45. Previous research indicates a role of adipokines in inflammation and osteogenesis. Hence adipokines might also have a pathophysiological role in inflammation and new bone formation in patients with ankylosing ...

    Authors: Agnes Hartl, Joachim Sieper, Uta Syrbe, Joachim Listing, Kay-Geert Hermann, Martin Rudwaleit and Denis Poddubnyy
    Citation: Arthritis Research & Therapy 2017 19:140
  46. Interferon (IFN)-α is thought to have a pivotal role in systemic lupus erythematosus (SLE), and type III IFNs (IFN-λ) were recently also associated with SLE. In this study, we measured levels of IFN-α, IFN-λ1,...

    Authors: Vilija Oke, Susanna Brauner, Anders Larsson, Johanna Gustafsson, Agneta Zickert, Iva Gunnarsson and Elisabet Svenungsson
    Citation: Arthritis Research & Therapy 2017 19:139
  47. Systemic lupus erythematosus (SLE) is a genetically complex rheumatic disease characterized by heterogeneous clinical manifestations of unknown etiology. Recent studies have suggested the existence of a geneti...

    Authors: Adrià Aterido, Antonio Julià, Patricia Carreira, Ricardo Blanco, José Javier López-Longo, José Javier Pérez Venegas, Àlex Olivé, José Luís Andreu, Maria Ángeles Aguirre-Zamorano, Paloma Vela, Joan M. Nolla, José Luís Marenco-de la Fuente, Antonio Zea, José María Pego, Mercedes Freire, Elvira Díez…
    Citation: Arthritis Research & Therapy 2017 19:138
  48. Leucine-rich alpha 2 glycoprotein (LRG) has been identified as a serum protein elevated in patients with active rheumatoid arthritis (RA). Although the function of LRG is ill-defined, LRG binds with transformi...

    Authors: Hayato Urushima, Minoru Fujimoto, Takashi Mishima, Tomoharu Ohkawara, Hiromi Honda, Hyun Lee, Hirohisa Kawahata, Satoshi Serada and Tetsuji Naka
    Citation: Arthritis Research & Therapy 2017 19:137

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  • Citation Impact 2023
    Journal Impact Factor: 4.4
    5-year Journal Impact Factor: 4.9
    Source Normalized Impact per Paper (SNIP): 1.294
    SCImago Journal Rank (SJR): 1.518

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    Submission to first editorial decision (median days): 9
    Submission to acceptance (median days): 111

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