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  1. Authors: Jun Qin, Liang Shang, An-song Ping, Jing Li, Xiao-jun Li, Hong Yu, Jacques Magdalou, Liao-bin Chen and Hui Wang
    Citation: Arthritis Research & Therapy 2013 15:407
    Content type: Erratum Published on:

    The original article was published in Arthritis Research & Therapy 2012 14:R242

  3. It is well established that an intimate connection exists between inflammation and neoplasia. Indeed, particular chronic infections and autoimmune processes giving rise to prolonged site-specific inflammation ...

    Authors: Jonathan P Sherlock, Andrew D Filer, John D Isaacs and Christopher D Buckley
    Citation: Arthritis Research & Therapy 2013 15:114
    Content type: Commentary Published on:

  4. Degeneration of the intervertebral disc (IVD) is characterized by marked degradation and restructuring of the annulus fibrosus (AF). Although several matrix metalloproteinases (MMPs) have been found to be more...

    Authors: Anshu Rastogi, Hyunchul Kim, Julianne D Twomey and Adam H Hsieh
    Citation: Arthritis Research & Therapy 2013 15:R57
    Content type: Research article Published on:

  5. Whereas the overall association between smoking and rheumatoid arthritis (RA) must be regarded as established, considerably less is known about how much smoking is needed to increase the risk of RA, that is, t...

    Authors: Daniela Di Giuseppe, Nicola Orsini, Lars Alfredsson, Johan Askling and Alicja Wolk
    Citation: Arthritis Research & Therapy 2013 15:R56
    Content type: Research article Published on:

  6. We sought to assess whether nailfold videocapillaroscopy (NVC) patterns are associated with levels of angiogenic factors in systemic sclerosis (SSc).

    Authors: Jérôme Avouac, Maeva Vallucci, Vanessa Smith, Patricia Senet, Barbara Ruiz, Alberto Sulli, Carmen Pizzorni, Camille Frances, Gilles Chiocchia, Maurizio Cutolo and Yannick Allanore
    Citation: Arthritis Research & Therapy 2013 15:R55
    Content type: Research article Published on:

  7. Treprostinil diethanolamine is an innovative salt form of the prostacyclin analogue, treprostinil sodium, developed as an oral sustained release (SR) osmotic tablet. The availability of a formulation permittin...

    Authors: Ami A Shah, Elena Schiopu, Laura K Hummers, Michael Wade, Kristine Phillips, Cynthia Anderson, Robert Wise, Francesco Boin, James R Seibold, Fredrick Wigley and Kristan D Rollins
    Citation: Arthritis Research & Therapy 2013 15:R54
    Content type: Research article Published on:

  8. Synovial macrophages, which can release proinflammatory factors, are responsible for the upregulation of cartilage-breakdown proteases and play critical roles in cartilage degradation during the progression of...

    Authors: Chih-Chang Yeh, Shun-Fu Chang, Ting-Ying Huang, Hsin-I Chang, Hsing-Chun Kuo, Yi-Chien Wu, Ching-Hsiang Hsieh, Chung-Sheng Shi and Cheng-Nan Chen
    Citation: Arthritis Research & Therapy 2013 15:R53
    Content type: Research article Published on:

  9. The objective was to investigate potential gene-environment interaction between body mass index (BMI) and each of eight TGFβ1 polymorphisms in knee and hip osteoarthritis (OA).

    Authors: Stella G Muthuri, Sally Doherty, Weiya Zhang, Rose A Maciewicz, Kenneth R Muir and Michael Doherty
    Citation: Arthritis Research & Therapy 2013 15:R52
    Content type: Research article Published on:

  10. Peroxisome proliferator-activated receptor (PPAR) agonists are widely used drugs in the treatment of diabetes and dyslipidemia. In addition to their metabolic effects, PPAR isoforms PPARα and PPARγ are also in...

    Authors: Erja-Leena Paukkeri, Tiina Leppänen, Mira Lindholm, Mun Fei Yam, Mohd Zaini Asmawi, Anne Kolmonen, Paula H Aulaskari and Eeva Moilanen
    Citation: Arthritis Research & Therapy 2013 15:R51
    Content type: Research article Published on:

  11. Autoantibodies to the Th/To antigen have been described in systemic sclerosis (SSc) and several proteins of the macromolecular Th/To complex have been reported to react with anti-Th/To antibodies. However, ant...

    Authors: Michael Mahler, Cristina Gascon, Sima Patel, Angela Ceribelli, Marvin J Fritzler, Andreas Swart, Edward KL Chan and Minoru Satoh
    Citation: Arthritis Research & Therapy 2013 15:R50
    Content type: Research article Published on:

  12. miRNAs have been shown to play essential regulatory roles in the innate immune system. They function at multiple levels to shape the innate immune response and maintain homeostasis by direct suppression of the...

    Authors: Xiaobing Luo, Koustubh Ranade, Ronel Talker, Bahija Jallal, Nan Shen and Yihong Yao
    Citation: Arthritis Research & Therapy 2013 15:210
    Content type: Review Published on:

  13. Adult and juvenile dermatomyositis share the hallmark features of pathognomic skin rash and muscle inflammation, but are heterogeneous disorders with a range of additional disease features and complications. T...

    Authors: Sarah L Tansley, Neil J McHugh and Lucy R Wedderburn
    Citation: Arthritis Research & Therapy 2013 15:211
    Content type: Review Published on:

  14. An NZB-derived genetic locus (Sle2c2) that suppresses autoantibody production in a mouse model of induced systemic lupus erythematosus contains a polymorphism in the gene encoding the G-CSF receptor. This study w...

    Authors: Margareta Lantow, Ramya Sivakumar, Leilani Zeumer, Clive Wasserfall, Ying-Yi Zheng, Mark A Atkinson and Laurence Morel
    Citation: Arthritis Research & Therapy 2013 15:R49
    Content type: Research article Published on:

  15. Autoantibodies and clinical manifestations in polymyositis/dermatomyositis (PM/DM) are affected by both genetic and environmental factors. The high prevalence of DM and anti-Mi-2 in Central America is thought ...

    Authors: Marcelo H Petri, Minoru Satoh, Beatriz T Martin-Marquez, Raul Vargas-Ramírez, Luis J Jara, Miguel A Saavedra, Claudia Cruz-Gonzalez, Lilia Andrade-Ortega, Olga Vera-Lastra, Mario Salazar-Páramo, Rosa E Prieto-Parra, Laura Gonzalez-Lopez, Jorge I Gamez-Nava, Hermes U Ramírez-Sánchez, Jason YF Chan, Steven J Ross…
    Citation: Arthritis Research & Therapy 2013 15:R48
    Content type: Research article Published on:

  16. B lymphocytes are the source of humoral immunity and are thus a critical component of the adaptive immune system. However, B cells can also be pathogenic and the origin of disease. Deregulated B-cell function ...

    Authors: Stephan Blüml, Kathleen McKeever, Rachel Ettinger, Josef Smolen and Ronald Herbst
    Citation: Arthritis Research & Therapy 2013 15(Suppl 1):S4
    Content type: Review Published on:

    This article is part of a Supplement: Volume 15 Supplement 1

  20. β2-microglobulin (β2m) is required for the surface expression of MHC class I and class I-like proteins such as CD1d, Qa1 and neonatal Fc receptor (FcRn), all of which may impact the development of autoimmunity...

    Authors: Ram Raj Singh, Jun-Qi Yang, Peter J Kim and Ramesh C Halder
    Citation: Arthritis Research & Therapy 2013 15:R47
    Content type: Research article Published on:

  21. Exercise training has emerged as a promising therapeutic strategy to counteract physical dysfunction in adult systemic lupus erythematosus. However, no longitudinal studies have evaluated the effects of an exe...

    Authors: Danilo ML Prado, Fabiana B Benatti, Ana L de Sá-Pinto, Ana P Hayashi, Bruno Gualano, Rosa MR Pereira, Adriana ME Sallum, Eloisa Bonfá, Clovis A Silva and Hamilton Roschel
    Citation: Arthritis Research & Therapy 2013 15:R46
    Content type: Research article Published on:

  22. In humans, different B-cell subpopulations can be distinguished in peripheral bloodand other tissues on the basis of differential expression of various surface markers.These different subsets correspond to dif...

    Authors: Maria J Leandro
    Citation: Arthritis Research & Therapy 2013 15(Suppl 1):S3
    Content type: Review Published on:

    This article is part of a Supplement: Volume 15 Supplement 1

  23. Over the past few decades small animal models mainly involving rodents and rabbits have been developed whereby needle puncture, stab incision or enzymatic approaches have been validated to create the degenerat...

    Authors: Mark Erwin
    Citation: Arthritis Research & Therapy 2013 15:113
    Content type: Editorial Published on:

  25. Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis has been implicated in the pathology of rheumatoid arthritis (RA), particularly as vulnerable personality types are exposed to chronic stress. Emo...

    Authors: Taavi Tillmann, Rajeev Krishnadas, Jonathan Cavanagh and KV Petrides
    Citation: Arthritis Research & Therapy 2013 15:R45
    Content type: Research article Published on:

  26. Although it is generally accepted that osteoarthritis is a degenerative condition of the cartilage, other tissues such as synovium in which immunological and inflammatory reactions occur contribute to the deve...

    Authors: Peter LEM van Lent and Wim B van den Berg
    Citation: Arthritis Research & Therapy 2013 15:112
    Content type: Editorial Published on:

  27. Magnetic resonance imaging (MRI) is increasingly being used in clinical trials of rheumatoid arthritis (RA) because of its superiority over x-ray radiography (XR) in detecting and monitoring change in bone ero...

    Authors: Charles G Peterfy, Ewa Olech, Julie C DiCarlo, Joan T Merrill, Peter J Countryman and Norman B Gaylis
    Citation: Arthritis Research & Therapy 2013 15:R44
    Content type: Research article Published on:

  29. Numerous studies across different health systems have documented that many patients with rheumatoid arthritis (RA) do not receive disease-modifying anti-rheumatic drugs (DMARDs). Relatively little is known abo...

    Authors: Daniel H Solomon, Edward Yelin, Jeffrey N Katz, Bing Lu, Tamara Shaykevich and John Z Ayanian
    Citation: Arthritis Research & Therapy 2013 15:R43
    Content type: Research article Published on:

  30. Although alcohol consumption is a common lifestyle behavior with previous studies reporting positive effects of alcohol on chronic pain and rheumatoid arthritis, no studies to this date have examined alcohol c...

    Authors: Chul H Kim, Ann Vincent, Daniel J Clauw, Connie A Luedtke, Jeffrey M Thompson, Terry D Schneekloth and Terry H Oh
    Citation: Arthritis Research & Therapy 2013 15:R42
    Content type: Research article Published on:

  32. Growth arrest-specific gene 6 protein (GAS6) and protein S (ProS) are vitamin K-dependent proteins present in plasma with important regulatory functions in systems of response and repair to damage. They intera...

    Authors: Pedro Recarte-Pelz, Dolors Tàssies, Gerard Espinosa, Begoña Hurtado, Núria Sala, Ricard Cervera, Joan Carles Reverter and Pablo García de Frutos
    Citation: Arthritis Research & Therapy 2013 15:R41
    Content type: Research article Published on:

    The Erratum to this article has been published in Arthritis Research & Therapy 2014 16:404

  37. Neuropsychiatric manifestations are common in childhood-onset systemic lupus erythematosus (cSLE) and often include neurocognitive dysfunction (NCD). Functional magnetic resonance imaging (fMRI) can measure br...

    Authors: Mark W DiFrancesco, Darren R Gitelman, Marisa S Klein-Gitelman, Anna Carmela P Sagcal-Gironella, Frank Zelko, Dean Beebe, Todd Parrish, Jessica Hummel, Jun Ying and Hermine I Brunner
    Citation: Arthritis Research & Therapy 2013 15:R40
    Content type: Research article Published on:

  39. The objective of this study was to investigate the potential role of the Toll-like receptor 7 (TLR7) signaling pathway in the pathogenesis of adult-onset Still's disease (AOSD).

    Authors: Der-Yuan Chen, Chi-Chen Lin, Yi-Ming Chen, Joung-Liang Lan, Wei-Ting Hung, Hsin-Hua Chen, Kuo-Lung Lai and Chia-Wei Hsieh
    Citation: Arthritis Research & Therapy 2013 15:R39
    Content type: Research article Published on:

  40. In lupus erythematosus, elevated serum creatinine levels and urinary abnormalities implicate a kidney disorder, which may not always be lupus nephritis as defined by the current classification of the Internati...

    Authors: Hans-Joachim Anders and Jan J Weening
    Citation: Arthritis Research & Therapy 2013 15:108
    Content type: Editorial Published on:

  41. Interleukin (IL)-36 refers to three related IL-1 family cytokines, IL-36α, IL-36β, and IL-36γ, that bind to the IL-36 receptor (IL-36R). IL-36 exerts proinflammatory effects in skin and lung and stimulates T c...

    Authors: Céline Lamacchia, Gaby Palmer, Emiliana Rodriguez, Praxedis Martin, Solenne Vigne, Christian A Seemayer, Dominique Talabot-Ayer, Jennifer E Towne and Cem Gabay
    Citation: Arthritis Research & Therapy 2013 15:R38
    Content type: Research article Published on:

  42. Detection of (subclinical) synovitis is relevant for both early diagnosis and monitoring of therapy of rheumatoid arthritis (RA). Previously, the potential of imaging (sub)clinical arthritis was demonstrated b...

    Authors: Yoony YJ Gent, Karin Weijers, Carla FM Molthoff, Albert D Windhorst, Marc C Huisman, Desirée EC Smith, Sumith A Kularatne, Gerrit Jansen, Philip S Low, Adriaan A Lammertsma and Conny J van der Laken
    Citation: Arthritis Research & Therapy 2013 15:R37
    Content type: Research article Published on:

  43. Manuscripts and abstracts from biomedical journals frequently do not contain proper information for meeting required standards and serving the multiple needs of their end users. Reporting guidelines and checkl...

    Authors: Robin Christensen, Henning Bliddal and Marius Henriksen
    Citation: Arthritis Research & Therapy 2013 15:109
    Content type: Commentary Published on:

  44. Lupus nephritis (LN) is a severe and frequent manifestation of systemic lupus erythematosus (SLE). Early detection of initial renal manifestations and relapses during follow-up is pivotal to prevent loss of re...

    Authors: Sebastian Dolff, Wayel H Abdulahad, Suzanne Arends, Marcory CRF van Dijk, Pieter C Limburg, Cees GM Kallenberg and Marc Bijl
    Citation: Arthritis Research & Therapy 2013 15:R36
    Content type: Research article Published on:

  45. The ability to ameliorate murine lupus renders regulatory T cells (Treg) a promising tool for the treatment of systemic lupus erythematosus (SLE). In consideration to the clinical translation of a Treg-based i...

    Authors: Olivia Weigert, Caroline von Spee, Reinmar Undeutsch, Lutz Kloke, Jens Y Humrich and Gabriela Riemekasten
    Citation: Arthritis Research & Therapy 2013 15:R35
    Content type: Research article Published on:

  46. Severe fatigue is a major health problem in fibromyalgia (FM). Obesity is common in FM, but the influence of adipokines and growth factors is not clear. The aim was to examine effects of exercise on fatigue, i...

    Authors: Jan L Bjersing, Malin Erlandsson, Maria I Bokarewa and Kaisa Mannerkorpi
    Citation: Arthritis Research & Therapy 2013 15:R34
    Content type: Research article Published on:

  47. Interleukin-1 (IL-1) blockade is the treatment of choice of cryopyrin associated periodic syndromes (CAPS). Anti-IL-1 monoclonal antibody (canakinumab) was recently registered. However no clear data are availa...

    Authors: Roberta Caorsi, Loredana Lepore, Francesco Zulian, Maria Alessio, Achille Stabile, Antonella Insalaco, Martina Finetti, Antonella Battagliese, Giorgia Martini, Chiara Bibalo, Alberto Martini and Marco Gattorno
    Citation: Arthritis Research & Therapy 2013 15:R33
    Content type: Research article Published on:

  49. Atherosclerosis, now regarded as a chronic inflammatory disease of the arterial wall, and its clinical manifestations have increasingly been associated with rheumatoid arthritis (RA), supporting the notion tha...

    Authors: Ghada S Hassan, Daniel Yacoub, Nada Alaaeddine, Amal Nadiri, Yahye Merhi and Walid Mourad
    Citation: Arthritis Research & Therapy 2013 15:206
    Content type: Review Published on:

  50. Collagen peptides have been reported to possess various biological activities for various cell types. The purposes of this study were, first, to examine the therapeutic effects of collagen tripeptide (Ctp) in ...

    Authors: Takuya Naraoka, Yasuyuki Ishibashi, Eiichi Tsuda, Yuji Yamamoto, Tomomi Kusumi and Satoshi Toh
    Citation: Arthritis Research & Therapy 2013 15:R32
    Content type: Research article Published on:
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Arthritis Research & Therapy

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