The MYOGEN study investigators, in addition to the authors of this article, who contributed to this study are as follows: Ingrid E. Lundberg (Rheumatology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden), Frederick W. Miller (Environmental Autoimmunity Group, Clinical Research Branch, National Institute of Environmental Health Science, National Institutes of Health, Bethesda, MD, USA), Robert G. Cooper (MRC/ARUK Institute of Ageing and Chronic Disease, University of Liverpool, UK), William E. Ollier (Division of Population Health, Health Services Research and Primary Care, School of Health Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, UK), Peter K. Gregersen (The Robert S Boas Center for Genomics and Human Genetics, Feinstein Institute for Medical Research, Manhasset, NY, USA), Jiri Vencovsky (Institute of Rheumatology and Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic), Katalin Danko (Division of Clinical Immunology, Department of Internal Medicine, University of Debrecen, Debrecen, Hungary), Vidya Limaye (Rheumatology Unit, Royal Adelaide Hospital and University of Adelaide, Adelaide, Australia), Albert Selva-O’Callaghan (Department of Internal Medicine, Vall d’Hebron General Hospital, Barcelona, Spain), Pedro M. Machado, Michael G. Hanna (MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology, London, UK), Hazel Platt (Centre for Integrated Genomic Medical Research, University of Manchester, UK), Øyvind Molberg (Department of Rheumatology, Oslo University Hospital, Oslo, Norway), Olivier Benveniste (Pitié-Salpêtrière Hospital, UPMC, Assistance Publique – Hôpitaux de Paris, Paris, France), Timothy Radstake (Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands), Jan De Bleecker, Boel De Paepe (Department of Neurology, Neuromuscular Reference Centre, Ghent University Hospital, Ghent, Belgium), Britta Maurer (Department of Rheumatology and Center of Experimental Rheumatology, University Hospital Zurich, Zurich, Switzerland), Leonid Padyukov (Rheumatology Unit, Department of Medicine, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden), Terrance P. O’Hanlon (Environmental Autoimmunity Group, Clinical Research Branch, National Institute of Environmental Health Science, National Institutes of Health, Bethesda, MD, USA), Lucy R. Wedderburn (Arthritis Research UK Centre for Adolescent Rheumatology, and Institute of Child Health, University College London, London, UK), Christopher Denton (Royal Free Hospital, London, UK), Herman Mann (Institute of Rheumatology, Prague), David Hilton-Jones (John Radcliffe Hospital, Oxford, UK), Patrick Kiely (St. George’s Hospital, London, UK), Paul H. Plotz (National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA), Mark Gourley (National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA), Galina Marder (North Shore University Hospital, Great Neck, NY, USA). Neil J. McHugh and Zoe E. Betteridge (Department of Pharmacy and Pharmacology, University of Bath, Bath, UK) generated the autoantibody data used in this study.
Funding
This study was supported by Myositis UK, Medical Research Council (MRC) UK grant MR/N003322/1; Arthritis Research UK (18474), Association Francaise Contre Les Myopathies (AFM), the European Union Sixth Framework Programme (project AutoCure; LSH-018661), the European Science Foundation (ESF) within the framework of the Research Networking Programme European Myositis Network (EUMYONET), the Swedish Research Council and the regional agreement on medical training and clinical research (ALF) between Stockholm County Council and Karolinska Institutet, and the intramural research program of the National Institute of Environmental Health Sciences (NIEHS) of the National Institutes of Health (NIH). The Czech cohort was supported by Project for Conceptual Development of Research Organization 00023728 from the Ministry of Health in the Czech Republic. JEP is supported by a University of Manchester alumni “Research Impact” doctoral studentship and president’s doctoral scholar award. This report includes description of independent research supported by the National Institute for Health Research. The views expressed in this publication are those of the author(s) and not necessarily those of the NHS, the National Institute for Health Research or the Department of Health.
Availability of data and materials
The data that support the findings of this study are available from the Myositis Genetics Consortium (MYOGEN), but restrictions apply to the availability of these data, which were used under licence for the present study, and so are not publicly available. Data are, however, available from the authors upon reasonable request and with permission of MYOGEN.