Volume 3 Supplement 1

Innovative Rheumatology: Gene and Cell Therapies of Arthritis and Related Autoimmune Disorders. Second International Meeting

Meeting abstracts

21st European Workshop for Rheumatology Research.

Vienna, Austria1-4 March 2001

Adeno-associated virus preferentially transduces human compared to mouse synovium

Authors: K Jennings, S Katakura, H Burstein, G Gao, JM Wilson and R Hirsch

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P1

Content type: Meeting abstract Published on: 25 April 2001
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IKKbeta and p53 as therapeutic targets for arthritis

Authors: PP Tak

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P10

Content type: Meeting abstract Published on: 25 April 2001
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Engineering T cells and molecules for targeting joints and inflammation

Authors: Y Chernajovsky, A Annenkov, H Dreja and G Adams

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P11

Content type: Meeting abstract Published on: 25 April 2001
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Elimination of rheumatoid synovium in situ by Fas ligand 'gene scalpel™'

Authors: H Zhang, G Gao, G Clayburne, JM Wilson and HR Schumacher

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P12

Content type: Meeting abstract Published on: 25 April 2001
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Double and triple gene transfer in arthritis

Authors: U Müller-Ladner, E Neumann, M Fleck, T Pap, RE Gay, PD Robbins, JD Mountz, CH Evans, J Schölmerich and S Gay

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P13

Content type: Meeting abstract Published on: 25 April 2001
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Bone stem cell mediated gene therapy and tissue engineering

Authors: D Gazit

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P14

Content type: Meeting abstract Published on: 25 April 2001
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Enhanced chondrocyte apoptosis leads to abnormal cartilage in rats and cats with glycosaminoglycan storage diseases

Authors: CM Simonaro, ME Haskins and EH Schuchman

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P15

Content type: Meeting abstract Published on: 25 April 2001
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Transfer of protease inhibitors to inhibit cartilage destruction

Authors: WH van der Laan, T Pap, PHA Quax, JM TeKoppele, FC Breedveld, S Gay, RE Gay, JH Verheijen and TWJ Huizinga

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P16

Content type: Meeting abstract Published on: 25 April 2001
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Local interleukin-12 gene transfer promotes conversion of an acute to a chronic destructive murine streptococcal cell wall arthritis

Authors: LAB Joosten, M Heuvelmans-Jacobs, E Lubberts, FAJ van de Loo, MMA Helsen and WB van den Berg

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P17

Content type: Meeting abstract Published on: 25 April 2001
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inflammation-inducible intra-articular production of human IL-1 receptor antagonist results in a more efficient inhibition of collagen-induced arthritis than does constitutive expression of the same transgene

Authors: AC Bakker, FAJ van de Loo, MB Bennink, LAB Joosten, AW Varley, RS Munford and WB van den Berg

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P18

Content type: Meeting abstract Published on: 25 April 2001
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Using a tropism-modified adenoviral vector for the intra-articular production of IL-1 receptor antagonist results in a more efficient inhibition of collagen-induced arthritis than does a conventional Ad5 vector

Authors: AC Bakker, FAJ van de Loo, OJ Arntz, LAB Joosten, I Dmitriev, V Krasnykh, DT Curiel and WB van den Berg

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P19

Content type: Meeting abstract Published on: 25 April 2001
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Delivery of antisense constructs and ribozymes to inhibit cartilage destruction in the SCID mouse model of RA

Authors: T Pap, J Schedel, U Müller-Ladner, RE Gay, W Zacharias and S Gay

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P2

Content type: Meeting abstract Published on: 25 April 2001
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Local IL-17 gene therapy accelerates collagen arthritis with severe bone erosion and rank ligand and rank expression in synovial infiltrate and at bone erosion sites

Authors: E Lubberts, LAB Joosten, P Schwarzenberger, B Oppers, L van de Bersselaar, JK Kolls and WB van den Berg

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P20

Content type: Meeting abstract Published on: 25 April 2001
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Update on the contralateral effect in rabbit and mouse models

Authors: PD Robbins, ER Lechman, S-H Kim, A Gambotto, J Whalen, SC Ghivizanni, CH Evans, Z Mi and TJ Oligino

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P21

Content type: Meeting abstract Published on: 25 April 2001
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Viral, nonviral and peptide-mediated intra-articular transfer of genes and proteins

Authors: PD Robbins, Z Mi, X Lu, J Mai, SC Ghivizanni, CH Evans and TJ Oligino

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P22

Content type: Meeting abstract Published on: 25 April 2001
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In vitro and in vivo differentiation of mesenchymal stem cells into chondrocytes

Authors: D Noël, F Apparailly, V Millet, J Sany and C Jorgensen

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P23

Content type: Meeting abstract Published on: 25 April 2001
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Inhibition of collagen-induced arthritis in mice by inducible AAV-mediated transfer of viral IL-10 gene

Authors: F Apparailly, V Millet, C Jacquet, J Sany, C Noël and C Jorgensen

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P24

Content type: Meeting abstract Published on: 25 April 2001
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Development of lentiviral vectors for gene therapy of arthritis

Authors: M Militello, F Apparailly, Y-L Lin, C Mettling, C Jorgensen and P Corbeau

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P25

Content type: Meeting abstract Published on: 25 April 2001
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Factors influencing adenoviral gene transfer

Authors: TWJ Huizinga, P Goossens, E Pieterman, R Vogels and M Havenga

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P26

Content type: Meeting abstract Published on: 25 April 2001
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Induction of synovial apoptosis by gene transfer and peptide mediated protein transduction

Authors: TJ Oligino, Q Yao, S Wang, JC Glorioso, CH Evans, SC Ghivizzani, R Takate, R Barton and PD Robbins

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P27

Content type: Meeting abstract Published on: 25 April 2001
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Targeted adenoviral vectors

Authors: E Vigne, A Brie, K Martin, A Gillardeaux, P Opolon, M Perricaudet, M Latta-Mahieu, JF Dedieu and P Yeh

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P28

Content type: Meeting abstract Published on: 25 April 2001
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A member of the T-box family of transcription factors mediates cartilage formation in mesenchymal progenitors C3H10T1/2

Authors: A Hoffmann, S Czichos, C Kaps, D Bächner, H Mayer, BG Kurkalli, Y Zilberman, D Gazit and G Gross

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P29

Content type: Meeting abstract Published on: 25 April 2001
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Clinical evaluation of autologous chondrocytes for joint repair

Authors: M Brittberg, E Sjögren-Jansson, L Peterson and A Lindahl

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P3

Content type: Meeting abstract Published on: 25 April 2001
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Adenoviral-based overexpression of TIMP-1 reduces tissue damage in the joints of TNF-alpha transgenic mice

Authors: G Schett, S Hayer, M Tohidast-Akrad, B Jahn-Schmid, S Lang, F Kainberger, G Kollias, AC Newby, Q Xu, G Steiner and JS Smolen

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P30

Content type: Meeting abstract Published on: 25 April 2001
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Therapeutic targeting of osteoclasts by osteoprotegerin and bisphosphonates leads to a reduction of TNFalpha-mediated bone resorption

Authors: K Redlich, S Hayer, CR Dunstan, M Tohidast-Akrad, S Lang, G Kollias, G Steiner, JS Smolen and G Schett

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P31

Content type: Meeting abstract Published on: 25 April 2001
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Gene therapy for cartilage healing

Authors: SC Ghivizzani, TJ Oligino, E Gouze-Decaris, G Palmer, PD Robbins and CH Evans

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P32

Content type: Meeting abstract Published on: 25 April 2001
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Transfer and intra-articular expression of the IL-1Ra cDNA in human rheumatoid joints

Authors: CH Evans, PD Robbins, SC Ghivizzani, JH Herndon, MC Wasko, M Tomaino, R Kang, TA Muzzonigro, EM Elder, TL Whiteside and SC Watkins

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P33

Content type: Meeting abstract Published on: 25 April 2001
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In vitro and in vivo gene delivery using a lentiviral vector

Authors: E Gouze-Decaris, R Pawliuk, C Pilapil, P Leboulch, CH Evans and SC Ghivizzani

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P34

Content type: Meeting abstract Published on: 25 April 2001
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Engineered cells and cartilage healing

Authors: T Häupl, C Kaps, G Gross, GR Burmester and M Sittinger

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P35

Content type: Meeting abstract Published on: 25 April 2001
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Autologous bone marrow grafting of avascular osteonecrosis before collapse

Authors: P Hernigou

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P36

Content type: Meeting abstract Published on: 25 April 2001
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Retrovirally-engineered antigen-specific T cells home to the inflamed joints and suppress collagen-induced arthrtis

Authors: A Nakajima, CM Seroogy, MR Sandora, IH Tarner, GL Costa, C Taylor-Edwards, MH Bachman, CH Contag and C Garrison-Fathman

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P37

Content type: Meeting abstract Published on: 25 April 2001
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Retroviral gene therapy of collagen-induced arthritis by local delivery of IL-4

Authors: IH Tarner, A Nakajima, CM Seroogy, J Ermann, MR Sandora, CH Contag and CG Fathman

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P38

Content type: Meeting abstract Published on: 25 April 2001
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Identification and expression of novel genes in osteoarthritis

Authors: D Bar, A Faerman, A Grossman and O Segev

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P39

Content type: Meeting abstract Published on: 25 April 2001
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Viral gene transfer for bone healing

Authors: AWA Baltzer

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P4

Content type: Meeting abstract Published on: 25 April 2001
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Time-course of gene expression after electroporation in rat patellar chondrocytes

Authors: L Grossin, C Cournil, B Liagre, L Mir, S Etienne, C Guingamp, P Pottie, P Netter and P Gillet

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P40

Content type: Meeting abstract Published on: 25 April 2001
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Overexpression and induction of heat shock protein (Hsp) 70 protects in vitro and in vivofrom mono-iodoacetate (MIA)-induced chondrocytes death

Authors: C Cournil, B Liagre, L Grossin, C Vol, A Abid, JY Jouzeau, B Terlain, P Netter and P Gillet

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P41

Content type: Meeting abstract Published on: 25 April 2001
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High efficiency intramuscular plasmid electrotransfer: application for sustained plasmatic secretion of cytokines

Authors: D Scherman, M Bettan, V Deleuze, P Kreiss and M Bureau

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P42

Content type: Meeting abstract Published on: 25 April 2001
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Osteoprotegerin (OPG) gene therapy in animal models of osteoarticular disease

Authors: B Bolon, C Carter, M Daris, S Morony, G Campagnuolo, U Feige and J Sheng

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P5

Content type: Meeting abstract Published on: 25 April 2001
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In vivoselection of synovial specific targets using phage display technology

Authors: C Pitzalis

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P6

Content type: Meeting abstract Published on: 25 April 2001
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Evidence for re-differentiation of human chondrocytes seeded on a hyaluronan derivative scaffold

Authors: B Grigolo, G Lisignoli, A Piacentini, M Fiorini, L Roseti, EO Major, M Duca, A Pavesio and A Facchini

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P7

Content type: Meeting abstract Published on: 25 April 2001
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AKT regulates TNF-alpha-mediated apoptosis of rheumatoid arthritis synovial fibroblasts

Authors: JD Mountz, H-G Zhang, Y Wang, JF Xie, X Liang, H-C Hsu and DT Curiel

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P8

Content type: Meeting abstract Published on: 25 April 2001
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AAV mediated delivery of IL-4 prevents collagen-induced arthritis

Authors: N Bessis and M-C Boissier

Citation: Arthritis Research & Therapy 2001 3(Suppl 1):P9

Content type: Meeting abstract Published on: 25 April 2001
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Innovative Rheumatology: Gene and Cell Therapies of Arthritis and Related Autoimmune Disorders. Second International Meeting

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