Handel ML, McMorrow LB, Gravallese EM: Nuclear factor-kappa B in rheumatoid synovium. Localization of p50 and p65. Arthritis Rheum. 1995, 38: 1762-1770.
Article
CAS
PubMed
Google Scholar
Asahara H, Asanuma M, Ogawa N, Nishibayashi S, Inoue H: High DNA-binding activity of transcription factor NF-kappa B in synovial membranes of patients with rheumatoid arthritis. Biochem Mol Biol Int. 1995, 37: 827-832.
CAS
PubMed
Google Scholar
Makarov SS: NF-kappa B in rheumatoid arthritis: a pivotal regulator of inflammation, hyperplasia, and tissue destruction. Arthritis Res. 2001, 3: 200-206. 10.1186/ar300.
Article
PubMed Central
CAS
PubMed
Google Scholar
Pahl HL: Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene. 1999, 18: 6853-6866. 10.1038/sj.onc.1203239.
Article
CAS
PubMed
Google Scholar
Fujisawa K, Aono H, Hasunuma T, Yamamoto K, Mita S, Nishioka K: Activation of transcription factor NF-kappa B in human synovial cells in response to tumor necrosis factor alpha. Arthritis Rheum. 1996, 39: 197-203.
Article
CAS
PubMed
Google Scholar
Bondeson J, Foxwell B, Brennan F, Feldmann M: Defining therapeutic targets by using adenovirus: blocking NF-kappaB inhibits both inflammatory and destructive mechanisms in rheumatoid synovium but spares anti-inflammatory mediators. Proc Natl Acad Sci USA. 1999, 96: 5668-5673. 10.1073/pnas.96.10.5668.
Article
PubMed Central
CAS
PubMed
Google Scholar
Pope RM: Apoptosis as a therapeutic tool in rheumatoid arthritis. Nature Rev Immunol. 2002, 2: 527-535. 10.1038/nri846.
Article
CAS
Google Scholar
Seetharaman R, Mora AL, Nabozny G, Boothby M, Chen J: Essential role of T cell NF-kappa B activation in collagen-induced arthritis. J Immunol. 1999, 163: 1577-1583.
CAS
PubMed
Google Scholar
Campbell IK, Gerondakis S, O'Donnell K, Wicks IP: Distinct roles for the NF-kappaB1 (p50) and c-Rel transcription factors in inflammatory arthritis. J Clin Invest. 2000, 105: 1799-1806.
Article
PubMed Central
CAS
PubMed
Google Scholar
Tak PP, Gerlag DM, Aupperle KR, van de Geest DA, Overbeek M, Bennett BL, Boyle DL, Manning AM, Firestein GS: Inhibitor of nuclear factor kappaB kinase beta is a key regulator of synovial inflammation. Arthritis Rheum. 2001, 44: 1897-1907. 10.1002/1529-0131(200108)44:8<1897::AID-ART328>3.0.CO;2-4.
Article
CAS
PubMed
Google Scholar
Stein B, Yang MX: Repression of the interleukin-6 promoter by estrogen receptor is mediated by NF-kappa B and C/EBP beta. Mol Cell Biol. 1995, 15: 4971-4979.
Article
PubMed Central
CAS
PubMed
Google Scholar
Ray A, Prefontaine KE, Ray P: Down-modulation of interleukin-6 gene expression by 17 beta-estradiol in the absence of high affinity DNA binding by the estrogen receptor. J Biol Chem. 1994, 269: 12940-12946.
CAS
PubMed
Google Scholar
Ray P, Ghosh SK, Zhang DH, Ray A: Repression of interleukin-6 gene expression by 17 beta-estradiol: inhibition of the DNA-binding activity of the transcription factors NF-IL6 and NF-kappa B by the estrogen receptor. FEBS Letters. 1997, 409: 79-85. 10.1016/S0014-5793(97)00487-0.
Article
CAS
PubMed
Google Scholar
Deshpande R, Khalili H, Pergolizzi RG, Michael SD, Chang MD: Estradiol down-regulates LPS-induced cytokine production and NFκB activation in murine macrophages. Am J Reprod Immunol. 1997, 38: 46-54.
Article
CAS
PubMed
Google Scholar
Sun WH, Keller ET, Stebler BS, Ershler WB: Estrogen inhibits phorbol ester-induced I kappa B alpha transcription and protein degradation. Biochem Biophys Res Commun. 1998, 244: 691-695. 10.1006/bbrc.1998.8324.
Article
CAS
PubMed
Google Scholar
Harnish DC, Scicchitano MS, Adelman SJ, Lyttle CR, Karathanasis SK: The role of CBP in estrogen receptor cross-talk with nuclear factor-kappaB in HepG2 cells. Endocrinology. 2000, 141: 3403-3411. 10.1210/en.141.9.3403.
CAS
PubMed
Google Scholar
Speir E, Yu ZX, Takeda K, Ferrans VJ, Cannon RO: Competition for p300 regulates transcription by estrogen receptors and nuclear factor-kappa B in human coronary smooth muscle cells. Circ Res. 2000, 87: 1006-1011.
Article
CAS
PubMed
Google Scholar
Kuiper GGJM, Carlsson B, Grandian K, Enmark E, Haggblad J, Nilsson S, Gustafsson JA: Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptor alpha and beta. Endocrinology. 1997, 138: 863-870. 10.1210/en.138.3.863.
CAS
PubMed
Google Scholar
Tornwall J, Carey AB, Fox RI, Fox HS: Estrogen in autoimmunity: expression of estrogen receptors in thymic and autoimmune T cells. J Gend Specif Med. 1999, 2: 33-40.
CAS
PubMed
Google Scholar
Ushiyama T, Ueyama H, Inoue K, Ohkubo I, Hukuda S: Expression of genes for estrogen receptors alpha and beta in human articular chondrocytes. Osteoartheritis Cartilage. 1999, 7: 560-566. 10.1053/joca.1999.0260.
Article
CAS
Google Scholar
Cutolo M, Accardo S, Villaggio B, Barone A, Sulli A, Coviello DA, Carabbio C, Felli L, Miceli D, Farruggio R, et al: Androgen and estrogen receptors are present in primary cultures of human synovial macrophages. J Clin Endocrinol Metab. 1996, 81: 820-827. 10.1210/jc.81.2.820.
CAS
PubMed
Google Scholar
Liu SH, al-Shaikh R, Panossian V, Yang RS, Nelson SD, Soleiman N, Finerman GA, Lane JM: Primary immunolocalization of estrogen and progesterone target cells in the human anterior cruciate ligament. J Orthop Res. 1996, 14: 526-533. 10.1002/jor.1100140405.
Article
CAS
PubMed
Google Scholar
Cowley SM, Hoare S, Mosselman S, Parker MG: Estrogen receptors alpha and beta form heterodimers on DNA. J Biol Chem. 1997, 272: 19858-19862. 10.1074/jbc.272.32.19858.
Article
CAS
PubMed
Google Scholar
Pace P, Taylor J, Suntharalingam S, Coombes RC, Ali S: Human estrogen receptor beta binds DNA in a manner similar to and dimerizes with estrogen receptor alpha. J Biol Chem. 1997, 272: 25832-25838. 10.1074/jbc.272.41.25832.
Article
CAS
PubMed
Google Scholar
Tyree CM, Zou A, Allegretto EA: 17beta-Estradiol inhibits cytokine induction of the human E-selectin promoter. J Steroid Biochem Mol Biol. 2002, 80: 291-297. 10.1016/S0960-0760(02)00022-5.
Article
CAS
PubMed
Google Scholar
Valentine JE, Kalkhoven E, White R, Hoare S, Parker MG: Mutations in the estrogen receptor ligand binding domain discriminate between hormone-dependent transactivation and transrepression. J Biol Chem. 2000, 275: 25322-25329. 10.1074/jbc.M002497200.
Article
CAS
PubMed
Google Scholar
Chadwick CC, Chippari S, Matelan E, Borges-Marcucci L, Eckert AM, Keith JC, Albert LM, Leathurby Y, Harris HA, Bhat RA, et al: Identification of pathway selective estrogen receptor ligands that inhibit NF-κB transcriptional activity. Proc Natl Acad Sci USA.
Poole AR, Coombs RR: Rheumatoid-like joint lesions in rabbits injected intravenously with bovine serum. Int Arch Allergy Appl Immunol. 1977, 54: 97-113.
Article
CAS
PubMed
Google Scholar
Mankin HJ, Dorfman H, Lippiello L, Zarins A: Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips. II. Correlation of morphology with biochemical and metabolic data. J Bone Joint Surg. 1971, 53: 523-537.
CAS
PubMed
Google Scholar
Gianazza E, Eberini I, Villa P, Fratelli M, Pinna C, Wait R, Gemeiner M, Miller I: Monitoring the effects of drug treatment in rat models of disease by serum protein analysis. J Chromatogr B Analyt Technol Biomed Life Sci. 2002, 771: 107-130. 10.1016/S0378-4347(01)00562-X.
Article
CAS
PubMed
Google Scholar
Otterness IG: The value of C-reactive protein measurement in rheumatoid arthritis. Semin Arthritis Rheum. 1994, 24: 91-104.
Article
CAS
PubMed
Google Scholar
Muller-Ladner U, Gay RE, Gay S: Activation of synoviocytes. Curr Opin Rheumatol. 2000, 12: 186-194. 10.1097/00002281-200005000-00005.
Article
CAS
PubMed
Google Scholar
Khalkhali-Ellis Z, Seftor EA, Nieva DR, Handa RJ, Price RH, Kirschmann DA, Baragi VM, Sharma RV, Bhalla RC, Moore TL, et al: Estrogen and progesterone regulation of human fibroblast-like synoviocyte function in vitro: implications in rheumatoid arthritis. J Rheum. 2000, 27: 1622-1631.
CAS
PubMed
Google Scholar
Taurog JD: Arthritis in HLA-B27 transgenic animals. Am J Med Sci. 1998, 316: 250-256. 10.1097/00000441-199810000-00005.
Article
CAS
PubMed
Google Scholar
Waksman BH: Immune regulation in adjuvant disease and other arthritis models: relevance to pathogenesis of chronic arthritis. Scan J Immunol. 2002, 56: 12-34. 10.1046/j.1365-3083.2002.01106.x.
Article
CAS
Google Scholar
Van Eden W, Waksman BH: Immune regulation in adjuvant-induced arthritis: possible implications for innovative therapeutic strategies in arthritis. Arthritis Rheum. 2003, 48: 1788-1796. 10.1002/art.11077.
Article
PubMed
Google Scholar
Tsao PW, Suzuki T, Totsuka R, Murata T, Takagi T, Ohmachi Y, Fujimura H, Takata I: The effect of dexamethasone on the expression of activated NF-kappa B in adjuvant arthritis. Clin Immunol Immunopathol. 1997, 83: 173-178. 10.1006/clin.1997.4333.
Article
CAS
PubMed
Google Scholar
Badger AM, Blake SM, Dodds RA, Griswold DE, Swift BA, Rieman DJ, Stroup GB, Hoffman SJ, Gowen M: Idoxifene, a novel selective estrogen receptor modulator, is effective in a rat model of adjuvant-induced arthritis. J Pharmacol Exp Ther. 1999, 291: 1380-1386.
CAS
PubMed
Google Scholar
Jansson L, Olsson T, Holmdahl R: Estrogen induces a potent suppression of experimental autoimmune encephalomyelitis and collagen-induced arthritis in mice. J Neuroimmunol. 1994, 53: 203-207. 10.1016/0165-5728(94)90030-2.
Article
CAS
PubMed
Google Scholar
Holmdahl R, Jansson L: Estrogen-induced suppression of collagen arthritis. III. Adult thymectomy does not affect the course of arthritis or the estrogen-mediated suppression of T-cell immunity. Brain Behav Immun. 1988, 2: 123-132. 10.1016/0889-1591(88)90013-X.
Article
CAS
PubMed
Google Scholar
Kanik KS, Wilder RL: Hormonal alterations in rheumatoid arthritis, including the effects of pregnancy. Rheum Dis Clin North Am. 2000, 26: 805-823.
Article
CAS
PubMed
Google Scholar
D'Elia HF, Larsen A, Mattsson LA, Waltbrand E, Kvist G, Mellstrom D, Saxne T, Ohlsson C, Nordborg E, Carlsten H: Influence of hormone replacement therapy on disease progression and bone mineral density in rheumatoid arthritis. J Rheum. 2003, 30: 1456-1463.
PubMed
Google Scholar
Tuck CH, Holleran S, Berglund L: Hormonal regulation of lipoprotein(a) levels: effects of estrogen replacement therapy on lipoprotein(a) and acute phase reactants in postmenopausal women. Arterioscler Thromb Vasc Biol. 1997, 17: 1822-1829.
Article
CAS
PubMed
Google Scholar
Zanger D, Yang BK, Ardans J, Waclawiw MA, Csako G, Wahl LM, Cannon RO: Divergent effects of hormone therapy on serum markers of inflammation in postmenopausal women with coronary artery disease on appropriate medical management. J Am Coll Cardiol. 2000, 36: 1797-1802. 10.1016/S0735-1097(00)00952-9.
Article
CAS
PubMed
Google Scholar
Pradhan AD, Manson JE, Rossouw JE, Siscovick DS, Mouton CP, Rifai N, Wallace RB, Jackson RD, Pettinger MB, Ridker PM: Inflammatory biomarkers, hormone replacement therapy, and incident coronary heart disease: prospective analysis from the Women's Health Initiative observational study. JAMA. 2002, 288: 980-987. 10.1001/jama.288.8.980.
Article
CAS
PubMed
Google Scholar
El-Swefy SE, Asker ME, Ali SI, Mohammed HE: A novel concept to preserve the beneficial effects of hormone replacement therapy in bilaterally female ovariectomized rats: role of lovastatin therapy. Pharmacol Res. 2002, 45: 167-173. 10.1006/phrs.2001.0876.
Article
CAS
PubMed
Google Scholar
Kido J, Kido R, Suryono , Kataoka M, Fagerhol MK, Nagata T: Calprotectin release from human neutrophils is induced by Porphyromonas gingivalis lipopolysaccharide via the CD-14–Toll-like receptor–nuclear factor kappaB pathway. J Periodontal Res. 2003, 38: 557-563. 10.1034/j.1600-0765.2003.00691.x.
Article
CAS
PubMed
Google Scholar
Han W, Lou Y, Tang J, Zhang Y, Chen Y, Li Y, Gu W, Huang J, Gui L, Tang Y, et al: Molecular cloning and characterization of chemokine-like factor 1 (CKLF1), a novel human cytokine with unique structure and potential chemotactic activity. Biochem J. 2001, 357: 127-135. 10.1042/0264-6021:3570127.
Article
PubMed Central
CAS
PubMed
Google Scholar
McInnes IB, Leung BP, Liew FY: Cell–cell interactions in synovitis. Interactions between T lymphocytes and synovial cells. Arthritis Res. 2000, 2: 374-378. 10.1186/ar115.
Article
PubMed Central
CAS
PubMed
Google Scholar
Ushiyama T, Inoue K, Nishioka J: Expression of estrogen receptor related protein (p29) and estradiol binding in human arthritic synovium. J Rheum. 1995, 22: 421-426.
CAS
PubMed
Google Scholar