Arend WP, Dayer JM: Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis. Arthritis Rheum. 1990, 33: 305-315. 10.1002/art.1780330302.
Article
CAS
PubMed
Google Scholar
O'Neill LA: The interleukin-1 receptor/Toll-like receptor superfamily: 10 years of progress. Immunol Rev. 2008, 226: 10-18. 10.1111/j.1600-065X.2008.00701.x.
Article
PubMed
Google Scholar
Garlanda C, Riva F, Polentarutti N, Buracchi C, Sironi M, De Bortoli M, Muzio M, Bergottini R, Scanziani E, Vecchi A, Hirsch E, Mantovani A: Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family. Proc Natl Acad Sci USA. 2004, 101: 3522-3526. 10.1073/pnas.0308680101.
Article
PubMed Central
CAS
PubMed
Google Scholar
Lech M, Kulkarni OP, Pfeiffer S, Savarese E, Krug A, Garlanda C, Mantovani A, Anders HJ: Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens. J Exp Med. 2008, 205: 1879-1888. 10.1084/jem.20072646.
Article
PubMed Central
CAS
PubMed
Google Scholar
Maedler K, Sergeev P, Ehses JA, Mathe Z, Bosco D, Berney T, Dayer JM, Reinecke M, Halban PA, Donath MY: Leptin modulates beta cell expression of IL-1 receptor antagonist and release of IL-1β in human islets. Proc Natl Acad Sci USA. 2004, 101: 8138-8143. 10.1073/pnas.0305683101.
Article
PubMed Central
CAS
PubMed
Google Scholar
Molnarfi N, Gruaz L, Dayer JM, Burger D: Opposite regulation of IL-1β and secreted IL-1 receptor antagonist production by phosphatidylinositide-3 kinases in human monocytes activated by lipopolysaccharides or contact with T cells. J Immunol. 2007, 178: 446-454.
Article
CAS
PubMed
Google Scholar
Molnarfi N, Brandt KJ, Gruaz L, Dayer JM, Burger D: Differential regulation of cytokine production by PI3Kδ in human monocytes upon acute and chronic inflammatory conditions. Mol Immunol. 2008, 45: 3419-3427. 10.1016/j.molimm.2008.04.001.
Article
CAS
PubMed
Google Scholar
Burger D, Molnarfi N, Weber MS, Brandt KJ, Benkhoucha M, Gruaz L, Chofflon M, Zamvil SS, Lalive PH: Glatiramer acetate increases IL-1 receptor antagonist but decreases T cell-induced IL-1β in human monocytes and multiple sclerosis. Proc Natl Acad Sci USA. 2009, 106: 4355-4359. 10.1073/pnas.0812183106.
Article
PubMed Central
CAS
PubMed
Google Scholar
Feldmann M, Maini RN: Anti-TNF alpha therapy of rheumatoid arthritis: what have we learned?. Annu Rev Immunol. 2001, 19: 163-196. 10.1146/annurev.immunol.19.1.163.
Article
CAS
PubMed
Google Scholar
Feldmann M, Maini SR: Role of cytokines in rheumatoid arthritis: an education in pathophysiology and therapeutics. Immunol Rev. 2008, 223: 7-19. 10.1111/j.1600-065X.2008.00626.x.
Article
CAS
PubMed
Google Scholar
Brennan FM, McInnes IB: Evidence that cytokines play a role in rheumatoid arthritis. J Clin Invest. 2008, 118: 3537-3545. 10.1172/JCI36389.
Article
PubMed Central
CAS
PubMed
Google Scholar
Kishimoto T: Interleukin-6: from basic science to medicine - 40 years in immunology. Annu Rev Immunol. 2005, 23: 1-21. 10.1146/annurev.immunol.23.021704.115806.
Article
CAS
PubMed
Google Scholar
Smolen JS, Aletaha D, Koeller M, Weisman MH, Emery P: New therapies for treatment of rheumatoid arthritis. Lancet. 2007, 370: 1861-1874. 10.1016/S0140-6736(07)60784-3.
Article
CAS
PubMed
Google Scholar
Seckinger P, Isaaz S, Dayer JM: Purification and biologic characterization of a specific tumor necrosis factor alpha inhibitor. J Biol Chem. 1989, 264: 11966-11973.
CAS
PubMed
Google Scholar
Peters M, Jacobs S, Ehlers M, Vollmer P, Mullberg J, Wolf E, Brem G, Meyer zum Buschenfelde KH, Rose-John S: The function of the soluble interleukin 6 (IL-6) receptor in vivo: sensitization of human soluble IL-6 receptor transgenic mice towards IL-6 and prolongation of the plasma half-life of IL-6. J Exp Med. 1996, 183: 1399-1406. 10.1084/jem.183.4.1399.
Article
CAS
PubMed
Google Scholar
Knupfer H, Preiss R: sIL-6R: more than an agonist?. Immunol Cell Biol. 2008, 86: 87-91. 10.1038/sj.icb.7100113.
Article
PubMed
Google Scholar
Muller-Newen G, Kuster A, Hemmann U, Keul R, Horsten U, Martens A, Graeve L, Wijdenes J, Heinrich PC: Soluble IL-6 receptor potentiates the antagonistic activity of soluble gp130 on IL-6 responses. J Immunol. 1998, 161: 6347-6355.
CAS
PubMed
Google Scholar
Simonet WS, Lacey DL, Dunstan CR, Kelley M, Chang MS, Luthy R, Nguyen HQ, Wooden S, Bennett L, Boone T, Shimamoto G, DeRose M, Elliott R, Colombero A, Tan HL, Trail G, Sullivan J, Davy E, Bucay N, Renshaw-Gegg L, Hughes TM, Hill D, Pattison W, Campbell P, Sander S, Van G, Tarpley J, Derby P, Lee R, Boyle WJ: Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell. 1997, 89: 309-319. 10.1016/S0092-8674(00)80209-3.
Article
CAS
PubMed
Google Scholar
Sheridan JP, Marsters SA, Pitti RM, Gurney A, Skubatch M, Baldwin D, Ramakrishnan L, Gray CL, Baker K, Wood WI, Goddard AD, Godowski P, Ashkenazi A: Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors. Science. 1997, 277: 818-821. 10.1126/science.277.5327.818.
Article
CAS
PubMed
Google Scholar
Mehrad B, Keane MP, Strieter RM: Chemokines as mediators of angiogenesis. Thromb Haemost. 2007, 97: 755-762.
PubMed Central
CAS
PubMed
Google Scholar
Mantovani A, Bonecchi R, Locati M: Tuning inflammation and immunity by chemokine sequestration: decoys and more. Nat Rev Immunol. 2006, 6: 907-918. 10.1038/nri1964.
Article
CAS
PubMed
Google Scholar
Charo IF, Ransohoff RM: The many roles of chemokines and chemokine receptors in inflammation. N Engl J Med. 2006, 354: 610-621. 10.1056/NEJMra052723.
Article
CAS
PubMed
Google Scholar
Peiper SC, Wang ZX, Neote K, Martin AW, Showell HJ, Conklyn MJ, Ogborne K, Hadley TJ, Lu ZH, Hesselgesser J, Horuk R: The Duffy antigen/receptor for chemokines (DARC) is expressed in endothelial cells of Duffy negative individuals who lack the erythrocyte receptor. J Exp Med. 1995, 181: 1311-1317. 10.1084/jem.181.4.1311.
Article
CAS
PubMed
Google Scholar
Gardner L, Patterson AM, Ashton BA, Stone MA, Middleton J: The human Duffy antigen binds selected inflammatory but not homeostatic chemokines. Biochem Biophys Res Commun. 2004, 321: 306-312. 10.1016/j.bbrc.2004.06.146.
Article
CAS
PubMed
Google Scholar
Du J, Luan J, Liu H, Daniel TO, Peiper S, Chen TS, Yu Y, Horton LW, Nanney LB, Strieter RM, Richmond A: Potential role for Duffy antigen chemokine-binding protein in angiogenesis and maintenance of homeostasis in response to stress. J Leukoc Biol. 2002, 71: 141-153.
PubMed Central
CAS
PubMed
Google Scholar
Addison CL, Belperio JA, Burdick MD, Strieter RM: Overexpression of the duffy antigen receptor for chemokines (DARC) by NSCLC tumor cells results in increased tumor necrosis. BMC Cancer. 2004, 4: 28-10.1186/1471-2407-4-28.
Article
PubMed Central
PubMed
Google Scholar
Nibbs RJ, Kriehuber E, Ponath PD, Parent D, Qin S, Campbell JD, Henderson A, Kerjaschki D, Maurer D, Graham GJ, Rot A: The beta-chemokine receptor D6 is expressed by lymphatic endothelium and a subset of vascular tumors. Am J Pathol. 2001, 158: 867-877.
Article
PubMed Central
CAS
PubMed
Google Scholar
Jamieson T, Cook DN, Nibbs RJ, Rot A, Nixon C, McLean P, Alcami A, Lira SA, Wiekowski M, Graham GJ: The chemokine receptor D6 limits the inflammatory response in vivo. Nat Immunol. 2005, 6: 403-411. 10.1038/ni1182.
Article
CAS
PubMed
Google Scholar
Martinez de la Torre Y, Locati M, Buracchi C, Dupor J, Cook DN, Bonecchi R, Nebuloni M, Rukavina D, Vago L, Vecchi A, Lira SA, Mantovani A: Increased inflammation in mice deficient for the chemokine decoy receptor D6. Eur J Immunol. 2005, 35: 1342-1346. 10.1002/eji.200526114.
Article
CAS
PubMed
Google Scholar
Martinez de la Torre Y, Buracchi C, Borroni EM, Dupor J, Bonecchi R, Nebuloni M, Pasqualini F, Doni A, Lauri E, Agostinis C, Bulla R, Cook DN, Haribabu B, Meroni P, Rukavina D, Vago L, Tedesco F, Vecchi A, Lira SA, Locati M, Mantovani A: Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6. Proc Natl Acad Sci USA. 2007, 104: 2319-2324. 10.1073/pnas.0607514104.
Article
PubMed Central
CAS
PubMed
Google Scholar
Nibbs RJ, Gilchrist DS, King V, Ferra A, Forrow S, Hunter KD, Graham GJ: The atypical chemokine receptor D6 suppresses the development of chemically induced skin tumors. J Clin Invest. 2007, 117: 1884-1892. 10.1172/JCI30068.
Article
PubMed Central
CAS
PubMed
Google Scholar
Heinzel K, Benz C, Bleul CC: A silent chemokine receptor regulates steady-state leukocyte homing in vivo. Proc Natl Acad Sci USA. 2007, 104: 8421-8426. 10.1073/pnas.0608274104.
Article
PubMed Central
CAS
PubMed
Google Scholar
D'Amico G, Frascaroli G, Bianchi G, Transidico P, Doni A, Vecchi A, Sozzani S, Allavena P, Mantovani A: Uncoupling of inflammatory chemokine receptors by IL-10: generation of functional decoys. Nat Immunol. 2000, 1: 387-391. 10.1038/80819.
Article
PubMed
Google Scholar
Cash JL, Hart R, Russ A, Dixon JP, Colledge WH, Doran J, Hendrick AG, Carlton MB, Greaves DR: Synthetic chemerin-derived peptides suppress inflammation through ChemR23. J Exp Med. 2008, 205: 767-775. 10.1084/jem.20071601.
Article
PubMed Central
CAS
PubMed
Google Scholar
Zabel BA, Nakae S, Zuniga L, Kim JY, Ohyama T, Alt C, Pan J, Suto H, Soler D, Allen SJ, Handel TM, Song CH, Galli SJ, Butcher EC: Mast cell-expressed orphan receptor CCRL2 binds chemerin and is required for optimal induction of IgE-mediated passive cutaneous anaphylaxis. J Exp Med. 2008, 205: 2207-2220. 10.1084/jem.20080300.
Article
PubMed Central
CAS
PubMed
Google Scholar
Mosmann TR, Schumacher JH, Street NF, Budd R, O'Garra A, Fong TA, Bond MW, Moore KW, Sher A, Fiorentino DF: Diversity of cytokine synthesis and function of mouse CD4+ T cells. Immunol Rev. 1991, 123: 209-229. 10.1111/j.1600-065X.1991.tb00612.x.
Article
CAS
PubMed
Google Scholar
Romagnani S: Human TH1 and TH2 subsets: doubt no more. Immunol Today. 1991, 12: 256-257. 10.1016/0167-5699(91)90120-I.
Article
CAS
PubMed
Google Scholar
Miossec P, Berg van den W: Th1/Th2 cytokine balance in arthritis. Arthritis Rheum. 1997, 40: 2105-2115. 10.1002/art.1780401203.
Article
CAS
PubMed
Google Scholar
Lubberts E, Joosten LA, Chabaud M, Bersselaar van Den L, Oppers B, Coenen-De Roo CJ, Richards CD, Miossec P, Berg van Den WB: IL-4 gene therapy for collagen arthritis suppresses synovial IL-17 and osteoprotegerin ligand and prevents bone erosion. J Clin Invest. 2000, 105: 1697-1710. 10.1172/JCI7739.
Article
PubMed Central
CAS
PubMed
Google Scholar
Harrington LE, Hatton RD, Mangan PR, Turner H, Murphy TL, Murphy KM, Weaver CT: Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol. 2005, 6: 1123-1132. 10.1038/ni1254.
Article
CAS
PubMed
Google Scholar
Bettelli E, Korn T, Kuchroo VK: Th17: the third member of the effector T cell trilogy. Curr Opin Immunol. 2007, 19: 652-657. 10.1016/j.coi.2007.07.020.
Article
PubMed Central
CAS
PubMed
Google Scholar
Aarvak T, Chabaud M, Miossec P, Natvig JB: IL-17 is produced by some proinflammatory Th1/Th0 cells but not by Th2 cells. J Immunol. 1999, 162: 1246-1251.
CAS
PubMed
Google Scholar
Cua DJ, Sherlock J, Chen Y, Murphy CA, Joyce B, Seymour B, Lucian L, To W, Kwan S, Churakova T, Zurawski S, Wiekowski M, Lira SA, Gorman D, Kastelein RA, Sedgwick JD: Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature. 2003, 421: 744-748. 10.1038/nature01355.
Article
CAS
PubMed
Google Scholar
Miossec P: Diseases that may benefit from manipulating the Th17 pathway. Eur J Immunol. 2009, 39: 667-669. 10.1002/eji.200839088.
Article
CAS
PubMed
Google Scholar
Steinman L: A rush to judgment on Th17. J Exp Med. 2008, 205: 1517-1522. 10.1084/jem.20072066.
Article
PubMed Central
CAS
PubMed
Google Scholar
Page G, Sattler A, Kersten S, Thiel A, Radbruch A, Miossec P: Plasma cell-like morphology of Th1-cytokine-producing cells associated with the loss of CD3 expression. Am J Pathol. 2004, 164: 409-417.
Article
PubMed Central
CAS
PubMed
Google Scholar
Zheng Y, Danilenko DM, Valdez P, Kasman I, Eastham-Anderson J, Wu J, Ouyang W: Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis. Nature. 2007, 445: 648-651. 10.1038/nature05505.
Article
CAS
PubMed
Google Scholar
Zrioual S, Ecochard R, Tournadre A, Lenief V, Cazalis MA, Miossec P: Genome-wide comparison between IL-17A- and IL-17F-induced effects in human rheumatoid arthritis synoviocytes. J Immunol. 2009, 182: 3112-3120. 10.4049/jimmunol.0801967.
Article
CAS
PubMed
Google Scholar
Ishigame H, Kakuta S, Nagai T, Kadoki M, Nambu A, Komiyama Y, Fujikado N, Tanahashi Y, Akitsu A, Kotaki H, Sudo K, Nakae S, Sasakawa C, Iwakura Y: Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses. Immunity. 2009, 30: 108-119. 10.1016/j.immuni.2008.11.009.
Article
CAS
PubMed
Google Scholar
Wang YH, Angkasekwinai P, Lu N, Voo KS, Arima K, Hanabuchi S, Hippe A, Corrigan CJ, Dong C, Homey B, Yao Z, Ying S, Huston DP, Liu YJ: IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC-activated Th2 memory cells. J Exp Med. 2007, 204: 1837-1847. 10.1084/jem.20070406.
Article
PubMed Central
CAS
PubMed
Google Scholar
Shull MM, Ormsby I, Kier AB, Pawlowski S, Diebold RJ, Yin M, Allen R, Sidman C, Proetzel G, Calvin D, et al: Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease. Nature. 1992, 359: 693-699. 10.1038/359693a0.
Article
PubMed Central
CAS
PubMed
Google Scholar
Bettelli E, Carrier Y, Gao W, Korn T, Strom TB, Oukka M, Weiner HL, Kuchroo VK: Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature. 2006, 441: 235-238. 10.1038/nature04753.
Article
CAS
PubMed
Google Scholar
Yoshida H, Yoshiyuki M: Regulation of immune responses by interleukin-27. Immunol Rev. 2008, 226: 234-247. 10.1111/j.1600-065X.2008.00710.x.
Article
CAS
PubMed
Google Scholar
Fitzgerald DC, Rostami A: Therapeutic potential of IL-27 in multiple sclerosis?. Expert Opin Biol Ther. 2009, 9: 149-160. 10.1517/14712590802646936.
Article
CAS
PubMed
Google Scholar
Collison LW, Workman CJ, Kuo TT, Boyd K, Wang Y, Vignali KM, Cross R, Sehy D, Blumberg RS, Vignali DA: The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature. 2007, 450: 566-569. 10.1038/nature06306.
Article
CAS
PubMed
Google Scholar
Boissier MC, Assier E, Biton J, Denys A, Falgarone G, Bessis N: Regulatory T cells (Treg) in rheumatoid arthritis. Joint Bone Spine. 2009, 76: 10-14. 10.1016/j.jbspin.2008.08.002.
Article
CAS
PubMed
Google Scholar
Burger D, Dayer JM: Cytokines, acute-phase proteins, and hormones: IL-1 and TNF-alpha production in contact-mediated activation of monocytes by T lymphocytes. Ann N Y Acad Sci. 2002, 966: 464-473. 10.1111/j.1749-6632.2002.tb04248.x.
Article
CAS
PubMed
Google Scholar
Xiao S, Jin H, Korn T, Liu SM, Oukka M, Lim B, Kuchroo VK: Retinoic acid increases Foxp3+ regulatory T cells and inhibits development of Th17 cells by enhancing TGF-β-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression. J Immunol. 2008, 181: 2277-2284.
Article
PubMed Central
CAS
PubMed
Google Scholar
Boonstra A, Barrat FJ, Crain C, Heath VL, Savelkoul HF, O'Garra A: 1α,25-Dihydroxyvitamin has a direct effect on naive D3 CD4(+) T cells to enhance the development of Th2 cells. J Immunol. 2001, 167: 4974-4980.
Article
CAS
PubMed
Google Scholar
Urry Z, Xystrakis E, Richards DF, McDonald J, Sattar Z, Cousins DJ, Corrigan CJ, Hickman E, Brown Z, Hawrylowicz CM: Ligation of TLR9 induced on human IL-10-secreting Tregs by 1α,25-dihydroxyvitamin D3 abrogates regulatory function. J Clin Invest. 2009, 119: 387-398.
PubMed Central
CAS
PubMed
Google Scholar
Chizzolini C, Chicheportiche R, Alvarez M, de Rham C, Roux-Lombard P, Ferrari-Lacraz S, Dayer JM: Prostaglandin E2 synergistically with interleukin-23 favors human Th17 expansion. Blood. 2008, 112: 3696-3703. 10.1182/blood-2008-05-155408.
Article
PubMed Central
CAS
PubMed
Google Scholar
Chabaud M, Aarvak T, Garnero P, Natvig JB, Miossec P: Potential contribution of IL-17-producing Th(1)cells to defective repair activity in joint inflammation: partial correction with Th(2)-promoting conditions. Cytokine. 2001, 13: 113-118. 10.1006/cyto.2000.0811.
Article
CAS
PubMed
Google Scholar
Chizzolini C, Chicheportiche R, Burger D, Dayer JM: Human Th1 cells preferentially induce interleukin (IL)-1α while Th2 cells induce IL-1 receptor antagonist production upon cell/cell contact with monocytes. Eur J Immunol. 1997, 27: 171-177. 10.1002/eji.1830270125.
Article
CAS
PubMed
Google Scholar
Goldring SR, Goldring MB: Eating bone or adding it: the Wnt pathway decides. Nat Med. 2007, 13: 133-134. 10.1038/nm0207-133.
Article
CAS
PubMed
Google Scholar
Fantuzzi G: Adiponectin and inflammation: consensus and controversy. J Allergy Clin Immunol. 2008, 121: 326-330. 10.1016/j.jaci.2007.10.018.
Article
CAS
PubMed
Google Scholar
Dayer JM, Chicheportiche R, Juge-Aubry C, Meier C: Adipose tissue has anti-inflammatory properties: focus on IL-1 receptor antagonist (IL-1Ra). Ann N Y Acad Sci. 2006, 1069: 444-453. 10.1196/annals.1351.043.
Article
CAS
PubMed
Google Scholar
Hu X, Herrero C, Li WP, Antoniv TT, Falck-Pedersen E, Koch AE, Woods JM, Haines GK, Ivashkiv LB: Sensitization of IFN-γ Jak-STAT signaling during macrophage activation. Nat Immunol. 2002, 3: 859-866. 10.1038/ni828.
Article
CAS
PubMed
Google Scholar
Tassiulas I, Hu X, Ho H, Kashyap Y, Paik P, Hu Y, Lowell CA, Ivashkiv LB: Amplification of IFN-α-induced STAT1 activation and inflammatory function by Syk and ITAM-containing adaptors. Nat Immunol. 2004, 5: 1181-1189. 10.1038/ni1126.
Article
CAS
PubMed
Google Scholar
Hu X, Paik PK, Chen J, Yarilina A, Kockeritz L, Lu TT, Woodgett JR, Ivashkiv LB: IFN-γ suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB/AP-1 proteins. Immunity. 2006, 24: 563-574. 10.1016/j.immuni.2006.02.014.
Article
CAS
PubMed
Google Scholar
Sharif MN, Tassiulas I, Hu Y, Mecklenbrauker I, Tarakhovsky A, Ivashkiv LB: IFN-α priming results in a gain of proinflammatory function by IL-10: implications for systemic lupus erythematosus pathogenesis. J Immunol. 2004, 172: 6476-6481.
Article
CAS
PubMed
Google Scholar
Yoshimura A, Naka T, Kubo M: SOCS proteins, cytokine signalling and immune regulation. Nat Rev Immunol. 2007, 7: 454-465. 10.1038/nri2093.
Article
CAS
PubMed
Google Scholar