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  1. Ankylosing Spondylitis (AS) is characterised by limitations in physical function. The Bath Ankylosing Spondylitis Functional Index (BASFI) is considered to be the gold-standard to assess physical function in A...

    Authors: Salima FE van Weely, J Christiaan van Denderen, Martijn PM Steultjens, Marike van der Leeden, Michael T Nurmohamed, Joost Dekker, Ben AC Dijkmans and Irene E van der Horst-Bruinsma
    Citation: Arthritis Research & Therapy 2012 14:R52
    Content type: Research article Published on:

  5. The longitudinal degradation mechanism of extracellular matrix (ECM) in the interbertebral disc remains unclear. Our objective was to elucidate catabolic and anabolic gene expression profiles and their balance...

    Authors: Takashi Yurube, Toru Takada, Teppei Suzuki, Kenichiro Kakutani, Koichiro Maeno, Minoru Doita, Masahiro Kurosaka and Kotaro Nishida
    Citation: Arthritis Research & Therapy 2012 14:R51
    Content type: Research article Published on:

  6. Autoantibodies to Ro52 recently identified as TRIM21 are among the most common autoantibodies in systemic autoimmune rheumatic diseases, but their clinical association remains poorly understood. We undertook t...

    Authors: Marie Hudson, Janet Pope, Michael Mahler, Solène Tatibouet, Russell Steele, Murray Baron and Marvin J Fritzler
    Citation: Arthritis Research & Therapy 2012 14:R50
    Content type: Research article Published on:

  7. Previous studies have indicated that transforming growth factor β (TGF-β) signaling has a critical role in cartilage homeostasis and repair, yet the mechanisms of TGF-β's chondroprotective effects are not know...

    Authors: Girish Ramaswamy, Philip Sohn, Alan Eberhardt and Rosa Serra
    Citation: Arthritis Research & Therapy 2012 14:R49
    Content type: Research article Published on:

  8. Polymyositis (PM) and dermatomyositis (DM) are chronic inflammatory muscle diseases, in which chemokines are thought to contribute to inflammatory cell migration into muscle. In this study, we retrospectively ...

    Authors: Fumihito Suzuki, Tetsuo Kubota, Yasunari Miyazaki, Kinya Ishikawa, Masashi Ebisawa, Shunsei Hirohata, Takashi Ogura, Hidehiro Mizusawa, Toshio Imai, Nobuyuki Miyasaka and Toshihiro Nanki
    Citation: Arthritis Research & Therapy 2012 14:R48
    Content type: Research article Published on:

  9. In their recent study, Sohn and colleagues identify multiple plasma proteins in the synovial fluid of patients with osteoarthritis (OA) and demonstrate the capacity of several of the proteins to activate macro...

    Authors: Steven R Goldring and Carla R Scanzello
    Citation: Arthritis Research & Therapy 2012 14:111
    Content type: Editorial Published on:

  10. Patient-reported physical function is an established outcome domain in clinical studies in rheumatology. To overcome the limitations of the current generation of questionnaires, the Patient-Reported Outcomes M...

    Authors: Martijn AH Oude Voshaar, Peter M ten Klooster, Erik Taal, Eswar Krishnan and Mart AFJ van de Laar
    Citation: Arthritis Research & Therapy 2012 14:R47
    Content type: Research article Published on:

  11. Systemic lupus erythematosus (SLE) is a chronic autoimmune disease. Cardiovascular disease (CVD) is common and a major cause of mortality. Studies on cardiovascular morbidity are abundant, whereas mortality st...

    Authors: Johanna T Gustafsson, Julia F Simard, Iva Gunnarsson, Kerstin Elvin, Ingrid E Lundberg, Lars-Olof Hansson, Anders Larsson and Elisabet Svenungsson
    Citation: Arthritis Research & Therapy 2012 14:R46
    Content type: Research article Published on:

  12. Osteoclastogenesis plays an important role in the bone erosion of rheumatoid arthritis (RA). Recently, Notch receptors have been implicated in the development of osteoclasts. However, the responsible Notch lig...

    Authors: Chiyoko Sekine, Akemi Koyanagi, Noriko Koyama, Katsuto Hozumi, Shigeru Chiba and Hideo Yagita
    Citation: Arthritis Research & Therapy 2012 14:R45
    Content type: Research article Published on:

  13. Rheumatoid arthritis (RA) is associated with increased cardiovascular morbidity and mortality attributed to both classical risk factors and chronic inflammation. We assessed longitudinally the factors associat...

    Authors: Evangelia Zampeli, Athanase Protogerou, Kimon Stamatelopoulos, Kalliopi Fragiadaki, Christina G Katsiari, Katerina Kyrkou, Christos M Papamichael, Myron Mavrikakis, Peter Nightingale, George D Kitas and Petros P Sfikakis
    Citation: Arthritis Research & Therapy 2012 14:R44
    Content type: Research article Published on:

  14. Rheumatoid arthritis (RA) is associated with hypogalactosylation of immunoglobulin G (IgG). We examined whether a proxy measure for galactosylation of IgG N-glycans could predict response to therapy or was dif...

    Authors: Altan Ercan, Jing Cui, Melissa M Hazen, Franak Batliwalla, Louise Royle, Pauline M Rudd, Jonathan S Coblyn, Nancy Shadick, Michael E Weinblatt, Peter Gregersen, David M Lee and Peter A Nigrovic
    Citation: Arthritis Research & Therapy 2012 14:R43
    Content type: Research article Published on:

  15. Rheumatoid arthritis (RA) is an inflammatory disease associated with accelerated atherosclerosis and high risk of cardiovascular (CV) disease. Since genome-wide association studies demonstrated association bet...

    Authors: Raquel López-Mejías, Carlos González-Juanatey, Mercedes García-Bermúdez, Santos Castañeda, José A Miranda-Filloy, Ricardo Blanco, Javier Llorca, Javier Martín and Miguel A González-Gay
    Citation: Arthritis Research & Therapy 2012 14:R42
    Content type: Research article Published on:

  22. Authors: Tomoo Sato, Ryoji Fujii, Koji Konomi, Naoko Yagishita, Satoko Aratani, Natsumi Araya, Hiroyuki Aono, Kazuo Yudoh, Noboru Suzuki, Moroe Beppu, Yoshihisa Yamano, Kusuki Nishioka and Toshihiro Nakajima
    Citation: Arthritis Research & Therapy 2012 14(Suppl 1):P61
    Content type: Poster presentation Published on:

    This article is part of a Supplement: Volume 14 Supplement 1

  38. Authors: Katsuya Hirasaka, Edward M Mills, Shohei Kohno, Tomoki Abe, Chika Ikeda, Tasuku Maeda, Shigetada Kondo, Ayako Maita, Yuushi Okumura and Takeshi Nikawa
    Citation: Arthritis Research & Therapy 2012 14(Suppl 1):P24
    Content type: Poster presentation Published on:

    This article is part of a Supplement: Volume 14 Supplement 1

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Arthritis Research & Therapy

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