Volume 14 Supplement 1

Proceedings of the 8th Global Arthritis Research Network (GARN) Meeting and 1st Bio-Rheumatology International Congress (BRIC)

Meeting abstracts

8th Global Arthritis Research Network (GARN) Meeting and 1st Bio-Rheumatology International Congress (BRIC).

Tokyo, Japan14-16 November 2011

Page 1 of 3

Future direction of pathogenesis and treatment for rheumatic disorders

Authors: Steffen Gay

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O1

Content type: Oral presentation Published on: 29 February 2012
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From rheumatic diseases to cancer - role of autoantibodies as diagnostic biomarkers

Authors: Eng M Tan

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O2

Content type: Oral presentation Published on: 29 February 2012
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Etiology and molecular pathogenesis of RA; how can we best use European initiatives to advance our knowledge?

Authors: Lars Klareskog

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O3

Content type: Oral presentation Published on: 29 February 2012
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Clinically isolated syndrome in collagen diseases; approaches and treatments

Authors: Kazumasa Yokoyama and Nobutaka Hattori

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O4

Content type: Oral presentation Published on: 29 February 2012
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Research platform for fibromyalgia in Japan

Authors: Kusuki Nishioka

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O5

Content type: Oral presentation Published on: 29 February 2012
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Recent advances in understanding of various chronic pain mechanisms through lysophosphatidic acid (LPA) receptor signaling

Authors: Hiroshi Ueda

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O6

Content type: Oral presentation Published on: 29 February 2012
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The role of mRNA degradation in immunity and inflammation

Authors: Shizuo Akira

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O7

Content type: Oral presentation Published on: 29 February 2012
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Death receptor-induced apoptosis signalling - essential guardian against autoimmune disease

Authors: Andreas Strasser, Lorraine A O'Reilly, Philipp Jost, Thomas Kaufmann, Stephanie Grabow, Elizabeth Kruse, Lin Tai, Mark Smyth and Philippe Bouillet

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O8

Content type: Oral presentation Published on: 29 February 2012
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Cancer immunotherapy; integration of T cell biology with nanogel- and vector-technology in translational research

Authors: Hiroshi Shiku

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O9

Content type: Oral presentation Published on: 29 February 2012
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Autoimmune arthritis caused by altered thymic T-cell selection due to a mutation of the ZAP-70 gene

Authors: Yoshinaga Ito and Shimon Sakaguchi

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O10

Content type: Oral presentation Published on: 29 February 2012
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Anti-Fas IgM monoclonal antibody (anti-Fas mAb) effect on haemophilic arthropathy (HA) synoviocytes

Authors: Serena Guiducci, Eloisa Romano, Claudia Ceccarelli, Daniela Melchiorre, Mirko Manetti, Anna F Milia, Lidia Ibba Manneshi, Kusuki Nishioka and Marco Matucci Cerinic

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O11

Content type: Oral presentation Published on: 29 February 2012
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Overview of osteoimmunology: What's happened? And what's going on?

Authors: Hiroshi Takayanagi

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O12

Content type: Oral presentation Published on: 29 February 2012
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Regulation of bone mass at unloaded condition by osteocyte network

Authors: Toshihisa Komori

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O13

Content type: Oral presentation Published on: 29 February 2012
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Assessment of histological alterations in cartilage and extracellular matrix driven by collagen-induced arthritis in Macaca fascicularis

Authors: Norio Amizuka, Hiromi Hongo, Muneteru Sasaki, Tomoka Hasegawa, Paulo Henrique Luiz de Freitas, Hiroshi Mori and Minqi Li

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O14

Content type: Oral presentation Published on: 29 February 2012
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Evidence for synovial fibroblasts spreading rheumatoid arthritis

Authors: Ulf Müller-Ladner, Stefanie Lefèvre, Birgit Zimmermann, Ingo H Tarner, Robert Dinser, Thomas Pap, Steffen Gay and Elena Neumann

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O15

Content type: Oral presentation Published on: 29 February 2012
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Skeletal involvement in the pathogenesis and outcomes of rheumatoid arthritis and osteoarthritis

Authors: Jean-Pierre Pelletier

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O16

Content type: Oral presentation Published on: 29 February 2012
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Fcγ receptor targeting in RA

Authors: Toshiyuki Takai, Akira Nakamura, Akiko Tobinai, Shota Endo and Masanori Inui

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O17

Content type: Oral presentation Published on: 29 February 2012
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Therapeutic targets for rheumatoid arthritis: lessons from animal models

Authors: Yoichiro Iwakura, Shinobu Saijo, Susumu Nakae, Noriyuki Fujikado, Harumichi Ishigame and Masanori Murayama

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O18

Content type: Oral presentation Published on: 29 February 2012
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Abnormal osteogenesis in osteoarthritis: gone with the Wnt?

Authors: Daniel Lajeunesse, Thomas F Chan, Aline Delalandre, Jean-Pierre Pelletier, Johanne Martel-Pelletier and Élie Abed

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O19

Content type: Oral presentation Published on: 29 February 2012
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Understanding the role of Fas-Fas ligand system in bone

Authors: Ana Marusic, Natasa Kovacic, Ivan Kresimir Lukic, Vedran Katavic and Danka Grcevic

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O20

Content type: Oral presentation Published on: 29 February 2012
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Regulation of inflammatory immune responses leading to the development of bone destructive autoimmune disease rheumatoid arthritis by IL-27

Authors: Takayuki Yoshimoto, Mingli Xu, Izuru Mizuguchi, Yukino Chiba, Sadahiro Kamiya, Masanori Matsui, Shiva Shahrara and Junichiro Mizuguchi

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O21

Content type: Oral presentation Published on: 29 February 2012
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Postnatal Syk deletion in mice clarifies the function of Syk in an anti-collagen antibody-induced arthritis model

Authors: Naoko Ozaki, Shinobu Suzuki, Hiromitsu Hara and Hiroki Yoshida

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O22

Content type: Oral presentation Published on: 29 February 2012
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Synoviolin meets metabolic disorders

Authors: Naoko Yagishita, Satoko Aratani, Daisuke Hasegawa, Yoshihisa Yamano, Kusuki Nishioka and Toshihiro Nakajima

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O23

Content type: Oral presentation Published on: 29 February 2012
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IL-17, synoviolin and rheumatoid arthritis chronicity

Authors: Pierre Miossec

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O24

Content type: Oral presentation Published on: 29 February 2012
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Implication of microRNA-140 in osteoarthritis

Authors: Johanne Martel-Pelletier

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O25

Content type: Oral presentation Published on: 29 February 2012
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Osteoclastic bone resorption directly activates osteoblast function

Authors: Nobuyuki Udagawa

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O26

Content type: Oral presentation Published on: 29 February 2012
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Directed induction of chondrogenic cells from mouse dermal fibroblast culture

Authors: Noriyuki Tsumaki

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O27

Content type: Oral presentation Published on: 29 February 2012
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A systems approach reveals that the musculoskeletal tissues development and homeostasis network

Authors: Hiroshi Asahara

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O28

Content type: Oral presentation Published on: 29 February 2012
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Angiogenesis in rheumatoid arthritis: the role of fut 1

Authors: Alisa Erika Koch

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O29

Content type: Oral presentation Published on: 29 February 2012
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Citrullination of fibrinogen: generation of neoepitopes and enhancement of immunostimulatory properties

Authors: William H Robinson and Jeremy Sokolove

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O30

Content type: Oral presentation Published on: 29 February 2012
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Novel regulatory T cells controlling antibody production and systemic autoimmunity

Authors: Kazuhiko Yamamoto, Tomohisa Okamura and Keishi Fujio

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O31

Content type: Oral presentation Published on: 29 February 2012
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Innate and adaptive immune responses to dead and dying cells

Authors: Keith B Elkon and Yueng Peng

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O32

Content type: Oral presentation Published on: 29 February 2012
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From discovery of RANKL to clinical application of anti-human RANKL antibody

Authors: Hisataka Yasuda, Yuriko Furuya and Kohji Uchida

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O33

Content type: Oral presentation Published on: 29 February 2012
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Microparticles as antigenic targets in human and murine SLE

Authors: Anirudh Ullal and David S Pisetsky

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O34

Content type: Oral presentation Published on: 29 February 2012
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New mechanisms of action and signaling by TNF-α

Authors: Lionel B Ivashkiv

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O35

Content type: Oral presentation Published on: 29 February 2012
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Synovial fibroblasts display an uncontrolled inflammatory and tissue destructive response to TNF-α

Authors: George D Kalliolias, Janice Chen, Galina Grigoriev and Lionel B Ivashkiv

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O36

Content type: Oral presentation Published on: 29 February 2012
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Interleukin-6 as a therapeutic target in locomotor disorders

Authors: Norihiro Nishimoto, Miho Murakami, Takaji Matsutani, Jun Hashimoto and Nobuhiro Takagi

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O37

Content type: Oral presentation Published on: 29 February 2012
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Signal transduction inhibitors for the treatment of rheumatoid arthritis

Authors: Yoshiya Tanaka and Kunihiro Yamaoka

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O38

Content type: Oral presentation Published on: 29 February 2012
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Adult stem cell-based therapy for degenerative joint diseases

Authors: Peter G Alexander and Rocky S Tuan

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O39

Content type: Oral presentation Published on: 29 February 2012
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Peptide therapy in sepsis and inflammation: a novel strategy to suppress inflammation

Authors: Hidechika Okada and Alan Okada

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O40

Content type: Oral presentation Published on: 29 February 2012
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Overview of biotherapy in rheumatoid arthritis (RA)

Authors: Tsutomu Takeuchi and Hideto Kameda

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O41

Content type: Oral presentation Published on: 29 February 2012
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Anti-TNF antibody therapy induces IL-17 suppressing regulatory T cells in patients with rheumatoid arthritis

Authors: Jenny McGovern, Clare A Notley, Dao Nguyen, Claudia Mauri, David A Isenberg and Michael R Ehrenstein

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O42

Content type: Oral presentation Published on: 29 February 2012
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Combined effects of the hedgehog pathway inhibitor LDE225 and nilotinib in a random mutagenesis screen

Authors: Tetsuzo Tauchi

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O43

Content type: Oral presentation Published on: 29 February 2012
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Molecular mechanism of unloading-mediated muscle atrophy and development of its countermeasures

Authors: Takeshi Nikawa

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O44

Content type: Oral presentation Published on: 29 February 2012
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Regulation of immune cell responses by semaphorins and their receptors

Authors: Atsushi Kumanogoh and Hyota Takamatsu

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O45

Content type: Oral presentation Published on: 29 February 2012
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A novel NEDD8-binding protein modulates NF-κB signaling pathway

Authors: Osamu Takashima, Fuminori Tsuruta, Manato Ebina, Yu Kigoshi, Shingo Nakamura and Tomoki Chiba

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):O46

Content type: Oral presentation Published on: 29 February 2012
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Reconstruction of injured spinal cord by epigenetic regulation of transplanted neural stem cells

Authors: Masahiko Abematsu, Keita Tsujimura, Mariko Yamano, Michiko Saito, Kenji Kohno, Takao Setoguchi, Kazunori Yone, Kinichi Nakashima and Setsuro Komiya

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):P1

Content type: Poster presentation Published on: 29 February 2012
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Fukushimura Brain Bank (FBB) -Based in a private geriatric hospital-

Authors: Hiroyasu Akatsu, Akira Hori, Hidechika Okada, Yoshio Hashizume and Takayuki Yamamoto

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):P2

Content type: Poster presentation Published on: 29 February 2012
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IL-17-producing ^©™T cells are important for the development of arthritis in a rheumatoid arthritis model

Authors: Aoi Akitsu, Harumichi Ishigame, Shigeru Kakuta, Shinobu Saijo and Yoichiro Iwakura

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):P3

Content type: Poster presentation Published on: 29 February 2012
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Osteoporosis in Iraqi patients with thalassemia

Authors: Salim M AL Jadir, Mohamed Z Jalal, Median F AL Ghreer, Mozahem S AL Hamdani and Wamid R AL Omaree

Citation: Arthritis Research & Therapy 2012 14(Suppl 1):P4

Content type: Poster presentation Published on: 29 February 2012
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Proceedings of the 8th Global Arthritis Research Network (GARN) Meeting and 1st Bio-Rheumatology International Congress (BRIC)

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