Skip to main content

Articles

Page 35 of 155

  1. Following the onset of rheumatoid arthritis (RA), patients experience a functional decline caused by various joint symptoms which affects their activities of daily living and can lead to reduced work productiv...

    Authors: Yoshiya Tanaka, Hideto Kameda, Kazuyoshi Saito, Yuko Kaneko, Eiichi Tanaka, Shinsuke Yasuda, Naoto Tamura, Keishi Fujio, Takao Fujii, Toshihisa Kojima, Tatsuhiko Anzai, Chikuma Hamada, Yoshihisa Fujino, Shinya Matsuda and Hitoshi Kohsaka
    Citation: Arthritis Research & Therapy 2018 20:151
    Content type: Research article Published on:

  2. Methotrexate (MTX) remains the disease-modifying anti-rheumatic drug of first choice in rheumatoid arthritis (RA) but response varies. Predicting non-response to MTX could enable earlier access to alternative ...

    Authors: Jamie C. Sergeant, Kimme L. Hyrich, James Anderson, Kamilla Kopec-Harding, Holly F. Hope, Deborah P. M. Symmons, Anne Barton and Suzanne M. M. Verstappen
    Citation: Arthritis Research & Therapy 2018 20:147
    Content type: Research article Published on:

  3. Anti-citrullinated protein antibody (ACPA) reactivities precede clinical onset of rheumatoid arthritis (RA), and it has been suggested that ACPA reactivities towards distinct target proteins may be associated ...

    Authors: Maria Karolina Jonsson, Aase Haj Hensvold, Monika Hansson, Anna-Birgitte Aga, Joseph Sexton, Linda Mathsson-Alm, Martin Cornillet, Guy Serre, Siri Lillegraven, Bjørg-Tilde Svanes Fevang, Anca Irinel Catrina and Espen Andre Haavardsholm
    Citation: Arthritis Research & Therapy 2018 20:146
    Content type: Research article Published on:

  4. A pivotal role for adipose tissue homeostasis in systemic sclerosis (SSc) skin fibrosis is increasingly recognized. The nuclear receptor PPAR-γ is the master regulator of adipogenesis. Peroxisome proliferator ...

    Authors: Benjamin Korman, Roberta Goncalves Marangoni, Gabriel Lord, Jerrold Olefsky, Warren Tourtellotte and John Varga
    Citation: Arthritis Research & Therapy 2018 20:145
    Content type: Research article Published on:

  5. The findings of a previous study by Jin et al. have shown that microRNA (miR)-155 was upregulated in patients with acute gouty arthritis and enhanced the proinflammatory cytokines. There is no direct evidence ...

    Authors: Qibin Yang, Quanbo Zhang, Yufeng Qing, Li Zhou, Qingsheng Mi and Jingguo Zhou
    Citation: Arthritis Research & Therapy 2018 20:144
    Content type: Research article Published on:

    The Correction to this article has been published in Arthritis Research & Therapy 2018 20:177

  6. Gout has an increasing global prevalence. Underutilization of urate-lowering therapy (ULT) is thought to be common, via both suboptimal dosing and poor medication adherence. The aims of this study were to dete...

    Authors: Huai Leng Pisaniello, Susan Lester, David Gonzalez-Chica, Nigel Stocks, Marie Longo, Greg R. Sharplin, Eleonora Dal Grande, Tiffany K. Gill, Samuel L. Whittle and Catherine L. Hill
    Citation: Arthritis Research & Therapy 2018 20:143
    Content type: Research article Published on:

  7. Takayasu arteritis (TAK) is a systemic disease characterized by large vessel involvement. Although the vascular characteristics of TAK are well characterized, there is no well-organized study demonstrating the...

    Authors: Oh Chan Kwon, Sang-Won Lee, Yong-Beom Park, Ji Seon Oh, Sang Hoon Lee, Seokchan Hong, Chang-Keun Lee, Bin Yoo and Yong-Gil Kim
    Citation: Arthritis Research & Therapy 2018 20:142
    Content type: Research article Published on:

  8. We aimed to evaluate the diagnostic utility of pelvic radiographs versus magnetic resonance imaging (MRI) of the sacroiliac joints in children with suspected sacroiliitis.

    Authors: Pamela F. Weiss, Rui Xiao, Timothy G. Brandon, David M. Biko, Walter P. Maksymowych, Robert G. Lambert, Jacob L. Jaremko and Nancy A. Chauvin
    Citation: Arthritis Research & Therapy 2018 20:141
    Content type: Research article Published on:

  9. Depression is common among patients with axial spondyloarthritis (axSpA), but reports of its prevalence are highly variable. We performed a systematic review to (i) describe the prevalence of depression in axS...

    Authors: Sizheng Zhao, Daniel Thong, Natasha Miller, Stephen J. Duffield, David M. Hughes, Laura Chadwick and Nicola J. Goodson
    Citation: Arthritis Research & Therapy 2018 20:140
    Content type: Review Published on:

  10. Detailed molecular analyses of cells from rheumatoid arthritis (RA) synovium hold promise in identifying cellular phenotypes that drive tissue pathology and joint damage. The Accelerating Medicines Partnership...

    Authors: Laura T. Donlin, Deepak A. Rao, Kevin Wei, Kamil Slowikowski, Mandy J. McGeachy, Jason D. Turner, Nida Meednu, Fumitaka Mizoguchi, Maria Gutierrez-Arcelus, David J. Lieb, Joshua Keegan, Kaylin Muskat, Joshua Hillman, Cristina Rozo, Edd Ricker, Thomas M. Eisenhaure…
    Citation: Arthritis Research & Therapy 2018 20:139
    Content type: Research article Published on:

  11. Monocyte-derived dendritic cells (moDCs) play important roles in the pathogenesis of systemic lupus erythematosus (SLE). Aberrant expression of long noncoding RNAs (lncRNAs) could affect the function of moDCs....

    Authors: Yilun Wang, Shuang Chen, Sunyi Chen, Juan Du, Jinran Lin, Haihong Qin, Jie Wang, Jun Liang and Jinhua Xu
    Citation: Arthritis Research & Therapy 2018 20:138
    Content type: Research article Published on:

  12. Accumulating evidence implicates mitochondrial DNA (mtDNA) alleles, which are independent of the nuclear genome, in disease, especially in human metabolic diseases. However, this area of investigation has lagg...

    Authors: Chia-Chun Tseng, Chung-Jen Chen, Jeng-Hsien Yen, Hsi-Yuan Huang, Jan-Gowth Chang, Shun-Jen Chang and Wei-Ting Liao
    Citation: Arthritis Research & Therapy 2018 20:137
    Content type: Research article Published on:

  13. Gout treatment remains suboptimal. Identifying populations at risk of developing gout may provide opportunities for prevention. Our aim was to assess the risk of incident gout associated with obesity, hyperten...

    Authors: Peter L. Evans, James A. Prior, John Belcher, Christian D. Mallen, Charles A. Hay and Edward Roddy
    Citation: Arthritis Research & Therapy 2018 20:136
    Content type: Research article Published on:

  14. Increased coffee intake is associated with reduced serum urate concentrations and lower risk of gout. Specific alleles of the GCKR, ABCG2, MLXIPL, and CYP1A2 genes have been associated with both reduced coffee in...

    Authors: Joseph Hutton, Tahzeeb Fatima, Tanya J. Major, Ruth Topless, Lisa K. Stamp, Tony R. Merriman and Nicola Dalbeth
    Citation: Arthritis Research & Therapy 2018 20:135
    Content type: Research article Published on:

  15. Dermatomyositis and polymyositis are the best known idiopathic inflammatory myopathies (IIMs). Classic histopathologic findings include the infiltration of inflammatory cells into muscle tissues. Neutrophil se...

    Authors: Siming Gao, Xiaoxia Zuo, Di Liu, Yizhi Xiao, Honglin Zhu, Huali Zhang and Hui Luo
    Citation: Arthritis Research & Therapy 2018 20:134
    Content type: Research article Published on:

  16. Hydroxychloroquine (HCQ) retinopathy may be more common than previously recognized; recent ophthalmology guidelines have revised recommendations from ideal body weight (IBW)-based dosing to actual body weight ...

    Authors: April M. Jorge, Ronald B. Melles, Yuqing Zhang, Na Lu, Sharan K. Rai, Lucy H. Young, Karen H. Costenbader, Rosalind Ramsey-Goldman, S. Sam Lim, John M. Esdaile, Ann E. Clarke, M. B. Urowitz, Anca Askanase, Cynthia Aranow, Michelle Petri and Hyon Choi
    Citation: Arthritis Research & Therapy 2018 20:133
    Content type: Research article Published on:

  17. Chemerin is a chemoattractant involved in immunity that also functions as an adipokine. Chemerin is secreted as an inactive precursor (chem163S), and its activation requires proteolytic cleavages at its C-term...

    Authors: Lei Zhao, Yasuto Yamaguchi, Xiaomei Ge, William H. Robinson, John Morser and Lawrence L. K. Leung
    Citation: Arthritis Research & Therapy 2018 20:132
    Content type: Research article Published on:

  18. Changes of serum concentrations of glycated, oxidized, and nitrated amino acids and hydroxyproline and anticyclic citrullinated peptide antibody status combined by machine learning techniques in algorithms hav...

    Authors: Catherine Legrand, Usman Ahmed, Attia Anwar, Kashif Rajpoot, Sabah Pasha, Cécile Lambert, Rose K. Davidson, Ian M. Clark, Paul J. Thornalley, Yves Henrotin and Naila Rabbani
    Citation: Arthritis Research & Therapy 2018 20:131
    Content type: Research article Published on:

  19. Previous studies have revealed that hepatitis B virus (HBV) infection may be related to rheumatoid arthritis (RA), but there are no studies on the presence of HBV antigens or nucleic acid in synovium from pati...

    Authors: Yu-Lan Chen, Jun Jing, Ying-Qian Mo, Jian-Da Ma, Li-Juan Yang, Le-Feng Chen, Xiang Zhang, Tao Yan, Dong-Hui Zheng, Frank Pessler and Lie Dai
    Citation: Arthritis Research & Therapy 2018 20:130
    Content type: Research article Published on:

  20. The phase III MONARCH randomized controlled trial (NCT02332590) demonstrated that in patients with rheumatoid arthritis (RA), sarilumab (anti-interleukin-6 receptor monoclonal antibody) monotherapy is superior...

    Authors: Vibeke Strand, Laure Gossec, Clare W. J. Proudfoot, Chieh-I Chen, Matthew Reaney, Sophie Guillonneau, Toshio Kimura, Janet van Adelsberg, Yong Lin, Erin K. Mangan, Hubert van Hoogstraten and Gerd R. Burmester
    Citation: Arthritis Research & Therapy 2018 20:129
    Content type: Research article Published on:

  21. In this study, we evaluated whether platelet-rich plasma (PRP) is superior to hyaluronic acid (HA) in the treatment of knee osteoarthritis.

    Authors: Yalong Di, Changxu Han, Liang Zhao and Yizhong Ren
    Citation: Arthritis Research & Therapy 2018 20:128
    Content type: Research article Published on:

  22. Rheumatoid arthritis (RA) is a chronic inflammatory disease in which adults have significant joint issues leading to poor health. Poor health is compounded by many factors, including exercise avoidance and inc...

    Authors: David B. Bartlett, Leslie H. Willis, Cris A. Slentz, Andrew Hoselton, Leslie Kelly, Janet L. Huebner, Virginia B. Kraus, Jennifer Moss, Michael J. Muehlbauer, Guillaume Spielmann, William E. Kraus, Janet M. Lord and Kim M. Huffman
    Citation: Arthritis Research & Therapy 2018 20:127
    Content type: Research article Published on:

  23. The application of more sensitive imaging techniques, such as ultrasonography (US), changed the concept of non-erosive arthritis in systemic lupus erythematosus (SLE), underlining the need for biomarkers to id...

    Authors: Fulvia Ceccarelli, Carlo Perricone, Tania Colasanti, Laura Massaro, Enrica Cipriano, Monica Pendolino, Francesco Natalucci, Riccardo Mancini, Francesca Romana Spinelli, Guido Valesini, Fabrizio Conti and Cristiano Alessandri
    Citation: Arthritis Research & Therapy 2018 20:126
    Content type: Research article Published on:

  24. Unfortunately, after publication of this article [1], it was noticed that the panel for Fig. 4b was inadvertently obscured during the production process. The full, correct Fig. 4 can be seen below and the orig...

    Authors: Jie Qian, Lingxiao Xu, Xiaoxuan Sun, Yani Wang, Wenhua Xuan, Qian Zhang, Pengfei Zhao, Qin Wu, Rui Liu, Nan Che, Fang Wang, Wenfeng Tan and Miaojia Zhang
    Citation: Arthritis Research & Therapy 2018 20:125
    Content type: Correction Published on:

    The original article was published in Arthritis Research & Therapy 2018 20:26

  25. Low C-C chemokine receptor 1 (CCR1) and interleukin (IL)-10 expression is associated with risk of Behçet’s disease (BD). The objective of the present study was to clarify the pathological roles of CCR1 and IL10 l...

    Authors: Hiroto Nakano, Yohei Kirino, Mitsuhiro Takeno, Kana Higashitani, Hideto Nagai, Ryusuke Yoshimi, Yukie Yamaguchi, Ikuma Kato, Ichiro Aoki and Hideaki Nakajima
    Citation: Arthritis Research & Therapy 2018 20:124
    Content type: Research article Published on:

  26. Rheumatoid arthritis (RA) patients are at high risk of developing cardiovascular disease (CVD). In RA, chronic inflammation may lead to endothelial dysfunction, an early indicator of CVD, owing to diminished n...

    Authors: Unnikrishnan M. Chandrasekharan, Zeneng Wang, Yuping Wu, W. H. Wilson Tang, Stanley L. Hazen, Sihe Wang and M. Elaine Husni
    Citation: Arthritis Research & Therapy 2018 20:123
    Content type: Research article Published on:

  27. Rotation or Change of Biotherapy After First Anti-TNF Treatment Failure for Rheumatoid Arthritis (ROC), registered 22 October 2009, NCT01000441

    Authors: Elodie Rivière, Jérémie Sellam, Juliette Pascaud, Philippe Ravaud, Jacques-Eric Gottenberg and Xavier Mariette
    Citation: Arthritis Research & Therapy 2018 20:122
    Content type: Letter Published on:

  28. Approaches for the prevention and treatment of hip osteoarthritis (OA) remain limited. There are recent data suggesting that low birth weight (LBW) and preterm birth may be risk factors for hip osteoarthritis....

    Authors: Sultana Monira Hussain, Ilana N. Ackerman, Yuanyuan Wang, Ella Zomer and Flavia M. Cicuttini
    Citation: Arthritis Research & Therapy 2018 20:121
    Content type: Review Published on:

  29. The pathogenesis of sacroiliitis is unclear; therefore, we aimed to systematically study the immunopathology of sacroiliitis in patients with axial spondyloarthritis (axSpA), and explore the relationship betwe...

    Authors: Dan min Wang, Ling Lin, Jian hua Peng, Yao Gong, Zhi duo Hou, Su biao Chen and Zheng yu Xiao
    Citation: Arthritis Research & Therapy 2018 20:120
    Content type: Research article Published on:

  30. Epidemiologic studies have highlighted the association of environmental factors with the development and progression of autoimmune and chronic inflammatory diseases. Among the environmental factors, smoking ha...

    Authors: Jhimmy Talbot, Raphael S. Peres, Larissa G. Pinto, Rene D. R. Oliveira, Kalil A. Lima, Paula B. Donate, Jaqueline R. Silva, Bernard Ryffel, Thiago M. Cunha, José C. Alves-Filho, Foo Y. Liew, Paulo Louzada-Junior and Fernando de Queiroz Cunha
    Citation: Arthritis Research & Therapy 2018 20:119
    Content type: Research article Published on:

  31. Systemic lupus erythematosus (SLE) is a chronic and incurable autoimmune disease involving the dysfunction of lymphocytes. Circular RNAs (circRNAs) are noncoding RNAs (ncRNAs) with a covalently closed loop str...

    Authors: Xin Wang, Chengzhong Zhang, Zhouwei Wu, Yue Chen and Weimin Shi
    Citation: Arthritis Research & Therapy 2018 20:118
    Content type: Research article Published on:

  32. The prevalence of dermatomyositis (DM) versus DM and polymyositis (PM) combined has been shown to be negatively associated with latitude. This observation has been attributed to increasing exposure to ultravio...

    Authors: Joanna E. Parkes, Simon Rothwell, Alexander Oldroyd, Hector Chinoy and Janine A. Lamb
    Citation: Arthritis Research & Therapy 2018 20:117
    Content type: Research article Published on:

  33. There is growing evidence that mast cells (MCs) play a role in knee osteoarthritis (OA). H1-antihistamines block H1-receptors of histamine, which is an important mediator of MCs. There is a lack of data on whethe...

    Authors: Ivan Shirinsky and Valery Shirinsky
    Citation: Arthritis Research & Therapy 2018 20:116
    Content type: Research article Published on:

  34. IL-17A has recently emerged as a potential target that regulates the extensive inflammation and abnormal bone formation observed in ankylosing spondylitis (AS). Blocking IL-17A is expected to inhibit bony anky...

    Authors: Sungsin Jo, Sung Eun Wang, Young Lim Lee, Suman Kang, Bitnara Lee, Jinil Han, Il-Hoon Sung, Ye-Soo Park, Sang-Cheol Bae and Tae-Hwan Kim
    Citation: Arthritis Research & Therapy 2018 20:115
    Content type: Research article Published on:

  35. B cells exert their pathogenic action in rheumatoid arthritis (RA) locally in the synovium. This study was undertaken to elucidate the chemokines responsible for the recruitment of B cells in the inflamed syno...

    Authors: Estefanía Armas-González, María Jesús Domínguez-Luis, Ana Díaz-Martín, Mayte Arce-Franco, Javier Castro-Hernández, Gabriela Danelon, Vanesa Hernández-Hernández, Sagrario Bustabad-Reyes, Alberto Cantabrana, Mariagrazia Uguccioni and Federico Díaz-González
    Citation: Arthritis Research & Therapy 2018 20:114
    Content type: Research article Published on:

  36. Pain is one of the most important domains affecting health-related quality of life (HRQoL) in patients with psoriatic arthritis (PsA). Secukinumab has demonstrated rapid and sustained improvements in signs and...

    Authors: Iain B. McInnes, Philip J. Mease, Georg Schett, Bruce Kirkham, Vibeke Strand, Nicole Williams, Todd Fox, Luminita Pricop, Steffen M. Jugl and Kunal K. Gandhi
    Citation: Arthritis Research & Therapy 2018 20:113
    Content type: Research article Published on:

  37. Aerobic exercise in general and high-intensity interval training (HIIT) specifically is known to improve vascular function in a range of clinical conditions. HIIT in particular has demonstrated improvements in...

    Authors: A. Mitropoulos, A. Gumber, H. Crank, M. Akil and M. Klonizakis
    Citation: Arthritis Research & Therapy 2018 20:112
    Content type: Research article Published on:

  38. Gout is a metabolic disease and is the most common form of inflammatory arthritis affecting men. However, the pathogenesis of gout is still uncertain, and novel biomarkers are needed for early prediction and d...

    Authors: Yannan Zhang, Huanzhen Zhang, Dong Chang, Fuchuan Guo, Hongzhi Pan and Yuexin Yang
    Citation: Arthritis Research & Therapy 2018 20:111
    Content type: Research article Published on:

  39. Prior qualitative research on gout has focused primarily on barriers to disease management. Our objective was to use patients’ perspectives to construct an explanatory framework to understand how patients beco...

    Authors: Alyssa Howren, Susan M. Cox, Kam Shojania, Sharan K. Rai, Hyon K. Choi and Mary A. De Vera
    Citation: Arthritis Research & Therapy 2018 20:110
    Content type: Research article Published on:

  41. The aim of this study is to examine the occurrence of comorbidities at the time of first diagnosis of gout compared with matched population controls, overall and by sex, as well as to examine the crude and age...

    Authors: Panagiota Drivelegka, Valgerdur Sigurdardottir, Anna Svärd, Lennart T. H. Jacobsson and Mats Dehlin
    Citation: Arthritis Research & Therapy 2018 20:108
    Content type: Research article Published on:

    The Correction to this article has been published in Arthritis Research & Therapy 2018 20:206

  42. The relationship between inflammation and blood pressure (BP) has been studied mainly in the general population. In this study, we examined the association between inflammation and BP across a broader range of...

    Authors: Zhi Yu, Seoyoung C. Kim, Kathleen Vanni, Jie Huang, Rishi Desai, Shawn N. Murphy, Daniel H. Solomon and Katherine P. Liao
    Citation: Arthritis Research & Therapy 2018 20:107
    Content type: Research article Published on:

    The Correction to this article has been published in Arthritis Research & Therapy 2019 21:170

  43. The perceived bother of skin and joint-related manifestations of psoriatic disease may differ among patients, rheumatologists, and dermatologists. This study identified and compared the patient and dermatologi...

    Authors: M. Elaine Husni, Anthony Fernandez, Brett Hauber, Rakesh Singh, Joshua Posner, Jessie Sutphin and Arijit Ganguli
    Citation: Arthritis Research & Therapy 2018 20:102
    Content type: Research article Published on:

  44. Achieving the best possible health-related quality of life (HRQoL) for a patient is an important treatment goal in juvenile idiopathic arthritis (JIA). We investigated the 36-month trajectories of HRQoL in chi...

    Authors: Miriam Listing, Kirsten Mönkemöller, Ina Liedmann, Martina Niewerth, Claudia Sengler, Joachim Listing, Dirk Foell, Arnd Heiligenhaus, Ariane Klein, Gerd Horneff, Gerd Ganser, Johannes-Peter Haas, Jens Klotsche and Kirsten Minden
    Citation: Arthritis Research & Therapy 2018 20:106
    Content type: Research article Published on:

  45. Evidence is emerging that pain in rheumatoid arthritis (RA) exists without underlying inflammation. Our objective was to evaluate the prognostic value of pain classification at treatment initiation using the p...

    Authors: Signe Rifbjerg-Madsen, Anton Wulf Christensen, Mikael Boesen, Robin Christensen, Bente Danneskiold-Samsøe, Henning Bliddal, Lene Dreyer, Henning Locht and Kirstine Amris
    Citation: Arthritis Research & Therapy 2018 20:105
    Content type: Research article Published on:

  46. Meniscal calcification is considered to play a relevant role in the pathogenesis of osteoarthritis of the knee. Little is known about the biology of acetabular labral disease and its importance in hip patholog...

    Authors: Thelonius Hawellek, Jan Hubert, Sandra Hischke, Matthias Krause, Jessica Bertrand, Burkhard C. Schmidt, Andreas Kronz, Klaus Püschel, Wolfgang Rüther and Andreas Niemeier
    Citation: Arthritis Research & Therapy 2018 20:104
    Content type: Research article Published on:

  49. Systemic lupus erythematosus (SLE) is a common systemic autoimmune disease with a complex genetic inheritance. Genome-wide association studies (GWAS) have significantly increased the number of significant loci...

    Authors: Antonio Julià, Francisco Javier López-Longo, José J. Pérez Venegas, Silvia Bonàs-Guarch, Àlex Olivé, José Luís Andreu, Mª. Ángeles Aguirre-Zamorano, Paloma Vela, Joan M. Nolla, José Luís Marenco de la Fuente, Antonio Zea, José María Pego-Reigosa, Mercedes Freire, Elvira Díez, Esther Rodríguez-Almaraz, Patricia Carreira…
    Citation: Arthritis Research & Therapy 2018 20:100
    Content type: Research article Published on:

  50. The term systemic juvenile idiopathic arthritis (sJIA) describes an autoinflammatory condition characterized by arthritis and severe systemic inflammation, which in later stages can transform into interleukin ...

    Authors: Boris Hügle, Anastasia Schippers, Nadine Fischer, Kim Ohl, Bernd Denecke, Fabio Ticconi, Bas Vastert, Ivan G. Costa, Johannes-Peter Haas and Klaus Tenbrock
    Citation: Arthritis Research & Therapy 2018 20:98
    Content type: Research article Published on:
  • Logo
Submit manuscript

Follow

Annual Journal Metrics

  • Citation Impact 2023
    Journal Impact Factor: 4.4
    5-year Journal Impact Factor: 4.9
    Source Normalized Impact per Paper (SNIP): 1.294
    SCImago Journal Rank (SJR): 1.518

    Speed 2023
    Submission to first editorial decision (median days): 9
    Submission to acceptance (median days): 111

    Usage 2023
    Downloads: 3,331,819
    Altmetric mentions: 1,885

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us