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  1. Approximately 100 loci have been definitively associated with rheumatoid arthritis (RA) susceptibility. However, they explain only a fraction of RA heritability. Interactions between polymorphisms could explai...

    Authors: Aida Ferreiro-Iglesias, Manuel Calaza, Eva Perez-Pampin, Francisco J Lopez Longo, Jose L Marenco, Francisco J Blanco, Javier Narvaez, Federico Navarro, Juan D Cañete, Arturo R de la Serna, Isidoro Gonzalez-Alvaro, Gabriel Herrero-Beaumont, Jose L Pablos, Alejandro Balsa, Benjamin Fernandez-Gutierrez, Rafael Caliz…
    Citation: Arthritis Research & Therapy 2014 16:436
    Content type: Research article Published on:

  2. CD4+CD25low/-GITR+ T lymphocytes expressing forkhead box protein P3 (FoxP3) and showing regulatory activity have been recently described in healthy donors. The objective of the study was to evaluate the proportio...

    Authors: Giuseppe Nocentini, Alessia Alunno, Maria Grazia Petrillo, Onelia Bistoni, Elena Bartoloni, Sara Caterbi, Simona Ronchetti, Graziella Migliorati, Carlo Riccardi and Roberto Gerli
    Citation: Arthritis Research & Therapy 2014 16:444
    Content type: Research article Published on:

  3. To compare statin initiation and treatment non-adherence following a first acute myocardial infarction (MI) in patients with inflammatory rheumatic disease ( IRD) and the general population.

    Authors: Megan Bohensky, Mark Tacey, Caroline Brand, Vijaya Sundararajan, Ian Wicks and Sharon Van Doornum
    Citation: Arthritis Research & Therapy 2014 16:443
    Content type: Research article Published on:

  4. This study aimed to evaluate whether profiles of several soluble mediators in synovial fluid and cartilage tissue are pathology-dependent and how their production is related to in vitro tissue formation by chondr...

    Authors: Anika I Tsuchida, Michiel Beekhuizen, Marieke C `t Hart, Timothy RDJ Radstake, Wouter JA Dhert, Daniel BF Saris, Gerjo JVM van Osch and Laura B Creemers
    Citation: Arthritis Research & Therapy 2014 16:441
    Content type: Research article Published on:

  6. Articular cartilage has a limited capacity to repair following injury. Early intervention is required to prevent progression of focal traumatic chondral and osteochondral defects to advanced cartilage degenera...

    Authors: Troy D Bornes, Adetola B Adesida and Nadr M Jomha
    Citation: Arthritis Research & Therapy 2014 16:432
    Content type: Review Published on:

  7. Arthritis is a multifactorial disease for which current therapeutic intervention with high efficacy remains challenging. Arthritis predominately affects articular joints, and cartilage deterioration and inflam...

    Authors: Carolyn M Dancevic and Daniel R McCulloch
    Citation: Arthritis Research & Therapy 2014 16:429
    Content type: Review Published on:

  8. Rheumatoid arthritis (RA) is a chronic inflammatory disease with striking heterogeneity in (i) clinical presentation, (ii) autoantibody profiles and (iii) responses to treatment suggesting that distinct molecu...

    Authors: Susan A Olalekan, Yanxia Cao and Alison Finnegan
    Citation: Arthritis Research & Therapy 2014 16:440
    Content type: Research article Published on:

  10. Personalized medicine is the holy grail of medicine. The EULAR recommendations for the management of rheumatoid arthritis (RA) support differential treatment between patients with baseline characteristics sugg...

    Authors: Iris M Markusse, Jeska K de Vries-Bouwstra, K Huub Han, Peter AHM van der Lubbe, Anne A Schouffoer, Pit JSM Kerstens, Willem F Lems, Tom WJ Huizinga and Cornelia F Allaart
    Citation: Arthritis Research & Therapy 2014 16:430
    Content type: Research article Published on:

  11. Biological drugs are effective in patients with rheumatoid arthritis (RA), but increase severe infections. The CC chemokine receptor (CCR) 9 antagonist was effective for Crohn’s disease without critical advers...

    Authors: Waka Yokoyama, Hitoshi Kohsaka, Kayoko Kaneko, Matthew Walters, Aiko Takayasu, Shin Fukuda, Chie Miyabe, Yoshishige Miyabe, Paul E Love, Nobuhiro Nakamoto, Takanori Kanai, Kaori Watanabe-Imai, Trevor T Charvat, Mark ET Penfold, Juan Jaen, Thomas J Schall…
    Citation: Arthritis Research & Therapy 2014 16:445
    Content type: Research article Published on:

  12. To assess if an impaired cross-talk between endothelial cells (ECs) and perivascular/multipotent mesenchymal stem cells (MSCs) might induce a perturbation of vascular repair and leading to a phenotypic switch ...

    Authors: Paola Cipriani, Paola Di Benedetto, Piero Ruscitti, Antonio Francesco Campese, Vasiliki Liakouli, Francesco Carubbi, Ilenia Pantano, Onorina Berardicurt, Isabella Screpanti and Roberto Giacomelli
    Citation: Arthritis Research & Therapy 2014 16:442
    Content type: Research article Published on:

  13. A key phenomenon in rheumatoid arthritis is the formation of lymphoid follicles in the inflamed synovial membrane. C-X-C motif chemokine 13 (CXCL13) is central in this process as it attracts C-X-C chemokine re...

    Authors: Stinne Ravn Greisen, Karen Kræmmer Schelde, Tue Kruse Rasmussen, Tue Wenzel Kragstrup, Kristian Stengaard-Pedersen, Merete Lund Hetland, Kim Hørslev-Petersen, Peter Junker, Mikkel Østergaard, Bent Deleuran and Malene Hvid
    Citation: Arthritis Research & Therapy 2014 16:434
    Content type: Research article Published on:

  18. Authors: Pin Lin, Elisa Rhew, Roberta B Ness, Alan Peaceman, Alan Dyer, David McPherson, George T Kondos, Daniel Edmundowicz, Kim Sutton-Tyrrell, Trina Thompson and Rosalind Ramsey-Goldman
    Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A46
    Content type: Meeting abstract Published on:

    This article is part of a Supplement: Volume 16 Supplement 1

  37. Authors: Eric Boilard, Vincent Bissonnette, Valérie Garceau, Ellie Aghdassi, Nathalie Cloutier, Claudia Beaudoin, Davy Eng, Stacey Morrison and Paul R Fortin
    Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A17
    Content type: Meeting abstract Published on:

    This article is part of a Supplement: Volume 16 Supplement 1

  46. Authors: Jiadi Xu, Zubin Patel, Leah Kottyan, Richard A Gatti, Deborah K McCurdy, Kenneth M Kaufman and John B Harley
    Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A7
    Content type: Meeting abstract Published on:

    This article is part of a Supplement: Volume 16 Supplement 1

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Arthritis Research & Therapy

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