Volume 16 Supplement 1

Lupus 2014: New Targets, New Approaches

Meeting abstracts

Edited by John Esdaile, Paul R Fortin, Matthew Liang, Peter Lipsky and Daniel Wallace

Publication charges for this supplement were funded by the conference.

Lupus 2014: New Targets, New Approaches.

Quebec City, Canada18-20 September 2014

Page 1 of 2

Moving lupus epidemiology forward: returning to the basics

Authors: Julia F Simard

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A1

Content type: Meeting abstract Published on: 18 September 2014
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Is prevention of systemic lupus erythematosus a goal?

Authors: Nancy J Olsen and David R Karp

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A2

Content type: Meeting abstract Published on: 18 September 2014
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Are patient ratings of interactions with providers and health plans associated with technical quality of care in systemic lupus erythematosus?

Authors: Edward Yelin, Laura Trupin and Jinoos Yazdany

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A3

Content type: Meeting abstract Published on: 18 September 2014
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Targeted delivery of PGE₂ ameliorates autoimmune nephritis

Authors: Nino Kvirkvelia, Maggie McMenaminn and Michael P Madaio

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A4

Content type: Meeting abstract Published on: 18 September 2014
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Lupus skin disease

Authors: Victoria P Werth

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A5

Content type: Meeting abstract Published on: 18 September 2014
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Modeling the stochastic behavior of lupus

Authors: Derry C Roopenian, Elisabeth B Adkins, Giljun Park, Herbert C Morse III and Gregory W Carter

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A6

Content type: Meeting abstract Published on: 18 September 2014
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DNA repair in lupus

Authors: Jiadi Xu, Zubin Patel, Leah Kottyan, Richard A Gatti, Deborah K McCurdy, Kenneth M Kaufman and John B Harley

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A7

Content type: Meeting abstract Published on: 18 September 2014
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Impact of genetic variants on B-cell development and function in systemic lupus erythematosus

Authors: Karen Cerosaletti, Tania Habib, Richard James, Janice Chen, Melissa Pickett, Andrew Funk, Shan Wei and Jane H Buckner

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A8

Content type: Meeting abstract Published on: 18 September 2014
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Differential methylation of interferon-related genes is associated with autoantibody production in systemic lupus erythematosus

Authors: Sharon A Chung, Joanne Nititham, Emon Elboudwarej, Hong L Quach, Kimberly E Taylor, Lisa F Barcellos and Lindsey A Criswell

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A9

Content type: Meeting abstract Published on: 18 September 2014
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Subphenotype mapping in systemic lupus erythematosus identifies multiple novel loci associated with circulating interferon alpha

Authors: Silvia N Kariuki, Yogita Ghodke-Puranik, Jessica M Dorschner, Beverly S Chrabot, Jennifer A Kelly, Betty P Tsao, Robert P Kimberly, Marta E Alarcón-Riquelme, Chaim O Jacob, Lindsey A Criswell, Kathy L Sivils, Carl D Langefeld, John B Harley, Andrew D Skol and Timothy B Niewold

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A10

Content type: Meeting abstract Published on: 18 September 2014
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Fine mapping and functional study of the systemic lupus erythematosus-associated NMNAT2/SMG7 locus

Authors: Jian Zhao, Yun Deng, Jennifer M Grossman and Betty P Tsao

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A11

Content type: Meeting abstract Published on: 18 September 2014
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Impact of provider specialty on the diagnosis and management of systemic lupus erythematosus in the American Indian/Alaska Native population

Authors: John A McDougall, Charles G Helmick, S Sam Lim, Caroline Gordon and Elizabeth D Ferucci

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A12

Content type: Meeting abstract Published on: 18 September 2014
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Racial discrimination and disease damage among African American women with systemic lupus erythematosus

Authors: David H Chae, Christina M Drenkard, Tené T Lewis and S Sam Lim

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A13

Content type: Meeting abstract Published on: 18 September 2014
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The Scleroderma Patient-centered Intervention Network for conducting large-scale international trials of nonpharmacological interventions in scleroderma: a way ahead for lupus?

Authors: Brett D Thombs

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A14

Content type: Meeting abstract Published on: 18 September 2014
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Linking anti-Ro antibodies to fibrosis in congenital heart block: translation to a clinical trial

Authors: Jill P Buyon, Peter Izmirly, Deborah Friedman and Joshua Copel

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A15

Content type: Meeting abstract Published on: 18 September 2014
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Targeting IRF5 inhibition in human B cells: identification of new functional roles that implicate IRF5 in systemic lupus erythematosus B-cell pathology

Authors: Saurav De, Di Feng, Alisha Valdez, Amy Pitler and Betsy J Barnes

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A16

Content type: Meeting abstract Published on: 18 September 2014
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Platelet-derived microparticles serve as an important source of autoantigens and discriminate between levels of disease activity in systemic lupus erythematosus

Authors: Eric Boilard, Vincent Bissonnette, Valérie Garceau, Ellie Aghdassi, Nathalie Cloutier, Claudia Beaudoin, Davy Eng, Stacey Morrison and Paul R Fortin

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A17

Content type: Meeting abstract Published on: 18 September 2014
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Vimentin is a dominant target of in situ humoral immunity in human lupus tubulointerstitial nephritis

Authors: Marcus R Clark, Anthony Chang, Kichul Ko, Carole J Henry Dunand, Scott Henderson, Dan Brandt, Natalya Kaverina, Vladimir Liarski, Patrick C Wilson and Andrew J Kinloch

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A18

Content type: Meeting abstract Published on: 18 September 2014
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Aggregation of MAVS antiviral protein suggests a mechanism for increased type I interferon production in SLE

Authors: Wen-Hai Shao, Brendan A Hilliard, Daniel H Shu, Stephen O Priest and Philip L Cohen

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A19

Content type: Meeting abstract Published on: 18 September 2014
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Aberrant expansion of CXCR5⁺ memory CD4 T cells in patients with systemic lupus erythematosus

Authors: Jin-Young Choi, Sang Taek Kim, Insoo Kang and Joe Craft

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A20

Content type: Meeting abstract Published on: 18 September 2014
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Identification of stage-specific genes associated with lupus nephritis and response to remission induction in NZB/W and NZM2410 mice

Authors: Ramalingam Bethunaickan, Celine C Berthier, Weijia Zhang, Ridvan Eksi, Hong-Dong Li, Yuanfang Guan, Matthias Kretzler and Anne Davidson

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A21

Content type: Meeting abstract Published on: 18 September 2014
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Blimp-1 and systemic lupus erythematosus

Authors: Betty Diamond, Sun Jung Kim, Sebastian Schaetzle and George Georgiou

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A22

Content type: Meeting abstract Published on: 18 September 2014
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A role for cutaneous gamma delta T cells in the development of systemic lupus erythematosus

Authors: Mehran Ghoreishi and Jan P Dutz

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A23

Content type: Meeting abstract Published on: 18 September 2014
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Neutrophils - a complex story in the pathogenesis of systemic lupus erythematosus

Authors: Christian Lood and Keith Elkon

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A24

Content type: Meeting abstract Published on: 18 September 2014
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mTOR activation triggers proinflammatory expansion of IL-4-producing and necrosis-prone double-negative T cells, precedes flares, and serves as target for treatment in patients with systemic lupus erythematosus

Authors: Zhi-Wei Lai, Rebecca Borsuk, Ashwini Shadakshari, Jianghong Yu, Maha Dawood, Ricardo Garcia, Lisa Francis, Hajra Tily, Adam Bartos, Stephen V Faraone, Paul Phillips and Andras Perl

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A25

Content type: Meeting abstract Published on: 18 September 2014
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Elucidating the role of TNF-like weak inducer of apoptosis in the pathogenesis of cutaneous lupus

Authors: Jessica Doerner, Jing Wen, Yumin Xia, Adam Friedman, Jennifer Michaelson, Linda Burkly, Lan Wu and Chaim Putterman

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A26

Content type: Meeting abstract Published on: 18 September 2014
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Phenotypic consequences of TLR7-driven interferon and proinflammatory cytokine production in lupus

Authors: Westley H Reeves, Haoyang Zhuang, Yuan Xu, Shuhong Han, Hai Wang and Lijun Yang

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A27

Content type: Meeting abstract Published on: 18 September 2014
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Interferon-alpha and angiogenic dysregulation in pregnant lupus patients destined for preeclampsia

Authors: Danieli Andrade, Mimi Kim, Luz P Blanco, S Ananth Karumanchi, Gloria C Koo, Patricia Redecha, Kyriakos Kirou, Angela M Alvarez, Melissa J Mulla, Mary K Crow, Vikki M Abrahams, Mariana J Kaplan and Jane E Salmon

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A28

Content type: Meeting abstract Published on: 18 September 2014
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Protective natural autoantibodies and lupus pathogenesis

Authors: Gregg J Silverman

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A29

Content type: Meeting abstract Published on: 18 September 2014
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A serine/threonine phosphatase, PP2A, controls autoimmunity

Authors: George C Tsokos

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A30

Content type: Meeting abstract Published on: 18 September 2014
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The opportunity and imperative for point-of-care diagnostics in systemic lupus erythematosus

Authors: Marvin J Fritzler

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A31

Content type: Meeting abstract Published on: 18 September 2014
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Molecular characterization of proliferative lupus nephritis

Authors: Samir V Parikh, Huijuan Song, Jay Vance, Jianying Zing, Lianbo Yu, Ana Malvar and Brad H Rovin

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A32

Content type: Meeting abstract Published on: 18 September 2014
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Disease features and outcomes among US lupus patients of Hispanic origin and their Mestizo counterpart in Latina America

Authors: Manuel Ugarte-Gil, Guillermo J Pons-Estel, Daniel Wojdyla, Gerald McGwin Jr, Bernardo A Pons-Estel and Graciela S Alarcón

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A33

Content type: Meeting abstract Published on: 18 September 2014
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Elevated risk of chronic obstructive pulmonary disease in systemic lupus erythematosus: a population-based study

Authors: Antonio Avina-Zubieta, Mohsen Sadatsafavi, Eric C Sayre and John Esdaile

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A34

Content type: Meeting abstract Published on: 18 September 2014
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Cancer risk factors in systemic lupus erythematosus: multivariate regression analysis in 16,409 patients

Authors: Sasha Bernatsky, Rosalind Ramsey-Goldman, Jean-François Boivin, Lawrence Joseph, Michelle A Petri, Asad Zoma, Susan Manzi, Murray B Urowitz, Dafna D Gladman, Paul R Fortin, Ellen M Ginzler, Edward Yelin, Sang-Cheol Bae, Daniel J Wallace, Steven M Edworthy, Soren Jacobsen…

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A35

Content type: Meeting abstract Published on: 18 September 2014
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Serological features of systemic lupus erythematosus diagnosed after referral through a rheumatology triage system because of positive antinuclear antibodies

Authors: Marvin J Fritzler, Whitney Steber, Terri Lupton, Christie Fitch-Rogalsky, Liam Martin, Susan G Barr and Ann Clarke

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A36

Content type: Meeting abstract Published on: 18 September 2014
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Sociodemographics and epidemiology of serious infections requiring hospitalization among adults with systemic lupus erythematosus and lupus nephritis, 2000 to 2006

Authors: Candace H Feldman, Linda T Hiraki, Wolfgang Winkelmayer, Francisco M Marty, Jessica M Franklin, Daniel H Solomon, Seoyoung C Kim and Karen H Costenbader

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A37

Content type: Meeting abstract Published on: 18 September 2014
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Preliminary population-based incidence and prevalence estimates of systemic lupus erythematosus: the California Lupus Surveillance Project

Authors: Maria C Dall'Era, Kurt Snipes, Miriam Cisternas, Caroline Gordon and Charles G Helmick

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A38

Content type: Meeting abstract Published on: 18 September 2014
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Serious infection incidence rates in pediatric systemic lupus erythematosus according to medication use

Authors: Linda T Hiraki, Candace H Feldman, Mary Beth Son, Jessica M Franklin, Michael A Fischer, Daniel H Solomon, Seoyoung C Kim, Wolfgang C Winkelmayer and Karen H Costenbader

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A39

Content type: Meeting abstract Published on: 18 September 2014
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Smoking and secondhand smoke among patients with systemic lupus erythematosus and controls: associations with disease and disease damage

Authors: Samantha J Minkin, Stephanie N Slan, Gary S Gilkeson and Diane L Kamen

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A40

Content type: Meeting abstract Published on: 18 September 2014
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High mortality in North American Natives with systemic lupus erythematosus

Authors: Christine A Peschken, Ripneet Puar and Carol A Hitchon

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A41

Content type: Meeting abstract Published on: 18 September 2014
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Optimal determination of Physician Global Assessment of lupus disease activity: a pilot study

Authors: Cynthia Aranow

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A42

Content type: Meeting abstract Published on: 18 September 2014
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Outcome measures in systemic lupus erythematosus: constructing a meaningful response index from existing clinical trial data

Authors: Lindsy Forbess, Daniel Wallace, Mariko Ishimori and Michael Weisman

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A43

Content type: Meeting abstract Published on: 18 September 2014
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Significance of cerebrovascular reactivity in patients with systemic lupus erythematosus

Authors: Jason Lazar, Louis Salciciolli, Elina Malamed and Ellen M Ginzler

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A44

Content type: Meeting abstract Published on: 18 September 2014
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'Lupus headache': results from a prospective, international, inception cohort study

Authors: John G Hanly

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A45

Content type: Meeting abstract Published on: 18 September 2014
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Adverse pregnancy outcomes and subsequent risk of cardiovascular disease in women with systemic lupus erythematosus

Authors: Pin Lin, Elisa Rhew, Roberta B Ness, Alan Peaceman, Alan Dyer, David McPherson, George T Kondos, Daniel Edmundowicz, Kim Sutton-Tyrrell, Trina Thompson and Rosalind Ramsey-Goldman

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A46

Content type: Meeting abstract Published on: 18 September 2014
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Methodological quality of studies of end-stage renal disease risks in lupus nephritis

Authors: Maria Tektonidou, Abhijit Dasgupta and Michael Ward

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A47

Content type: Meeting abstract Published on: 18 September 2014
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Patient-Centered Outcomes Research Institute (PCORI) multisite project to develop treatment decision aids for racial/ethnic minorities with lupus nephritis

Authors: Jinoos Yazdany, Maria Dall'Era and Jasvinder Singh

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A48

Content type: Meeting abstract Published on: 18 September 2014
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Clinical response to belimumab in academic clinical practices

Authors: Arthi Reddy, XiaoQing Li, Jill P Buyon, Andrew G Franks, Richard A Furie, Diane L Kamen, Susan Manzi, Michelle Petri, Rosalind Ramsey-Goldman, Chung-E Tseng, Ronald F van Vollenhoven, Daniel J Wallace and Anca D Askanase

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A49

Content type: Meeting abstract Published on: 18 September 2014
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Eculizumab in recalcitrant antiphospholipid antibody syndrome

Authors: Ekaterini Zapantis, Richard Furie and Diane Horowitz

Citation: Arthritis Research & Therapy 2014 16(Suppl 1):A50

Content type: Meeting abstract Published on: 18 September 2014
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